springer us springer new york okt 2008 (37 Ergebnisse)

Buch. Zustand: Neu. Neuware -A path player game is a new innovative type of game which considers network flow problems from the viewpoint of network owners. This strategy enables modeling real-world problems and has many practical applications.Key features:\* Presents a rigorous exposition of the theoretical foundations of the concept of a path player game;\* Suggests 18 practical open problems for future research in such areas as traffic planning, computation of equilibria, and optimization;\* Examines potentials for games on polyhedra as well as integer versions of generalized Nash equilibria.Written clearly, with well-presented mathematics, this book is intended for graduate students, mathematicians, engineers, and computer scientists.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 184 pp. Englisch.

Buch. Zustand: Neu. Neuware -Bioinformatics is an evolving field that is gaining popularity due to genomics, proteomics and other high-throughput biological methods. The function of bioinformatic scientists includes biological data storage, retrieval and in silico analysis of the results from large-scale experiments. This requires a grasp of knowledge mining algorithms, a thorough understanding of biological knowledge base, and the logical relationship of entities that describe a process or the system. Bioinformatics researchers are required to be trained in multidisciplinary fields of biology, mathematics and computer science. Currently the requirements are satisfied by ad hoc researchers who have specific skills in biology or mathematics/computer science. But the learning curve is steep and the time required to communicate using domain specific terms is becoming a major bottle neck in scientific productivity. This workbook provides hands-on experience which has been lacking for qualified bioinformatics researchers.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 204 pp. Englisch.

Buch. Zustand: Neu. Neuware -School activities alone are not always sufficient to ensure children¿s academic progress or socio-emotional development and well-being. And the time when many children typically have the least adult supervision ¿ immediately after school ¿ is also the time that they are at the highest risk to act as perpetrators or become victims of antisocial behavior.Throughout A Blueprint for Promoting Academic and Social Competence in After-School Programs, which focuses on children in grades 1 through 6, noted experts identify the best practices of effective programs and pinpoint methods for enhancing school-based skills and making them portable to home and neighborhood settings. This volume: (1) Analyzes the concepts central to effective after-school programs. (2) Offers developmental, cognitive, and social ecology perspectives on how children learn. (3) Features more than 100 exercises that develop young people¿s capabilities for academic, social, moral, and emotional learning ¿ These exercises are ready to use or can be adapted to students¿ unique needs. (4) Emphasizes young people¿s development as students and as productive members of society during middle to late childhood and early adolescence. (5) Presents explicit theory and evidence that can be used to explain the value of after-school programs for budget proposals.This important book will find an appreciative, ready audience among the program directors who design after-school curricula, the educators who implement them, the mental health and social work professionals who help staff them, and the current crop of graduate students who will create the next generation of programs.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 256 pp. Englisch.

Buch. Zustand: Neu. Neuware -Dramatic cases of child abuse and neglect are featured with tragic regularity in the news. The stories vividly demonstrate both the urgent need for improved child protection services and the unwieldiness and ineffectiveness of the systems charged with the task. To complicate matters further, the original intent of child welfare policy is becoming increasingly obscured as legal responses to child maltreatment become more complex, intrusive, and even contradictory.Fueled by a consistent narrative and a lucid ethical stance, Child Maltreatment and the Law analyzes the increasing role legal systems play in family life and traces rapidly evolving legal concepts as they apply to child protection. This unique volume helps readers: (1) Navigate the various layers of legal regulation ¿ federal and state ¿ involved in child protection and family life. (2) Identify variations and discrepancies in definitions of maltreatment and legal responses. (3) Critique the relationships and boundary disputes between the criminal and civil justice systems and agencies dedicated to children¿s welfare. (4) Analyze controversies (e.g., removing children from maltreating families) and other prime areas for possible reform.Child Maltreatment and the Law is a must-read for psychologists, developmentalists, sociologists, social workers, criminologists, and researchers focusing on family life as well as policymakers and advocates working within the legal system. The book is particularly useful for courses relating to child welfare law or child abuse and neglect.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 228 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -The study of the human-made world, whether it is called artifacts, material culture, or technology, has burgeoned across the academy. Archaeologists have for cen- ries led the way, and today offer investigators myriad programs and conceptual frameworks for engaging the things, ordinary and extraordinary, of everyday life. This book is an attempt by practitioners of one program ¿ Behavioral Archaeology ¿ to furnish between two covers some of our basic principles, heuristic tools, and illustrative case studies. Our greater purpose, however, is to engage the ideas of two competing programs ¿ agency/practice and evolution ¿ in hopes of initiating a dialog. We are convinced that there is enough overlap in goals, interests, and conceptions among these programs to warrant guarded optimism that a more encompassing, more coherent framework for studying the material world can result from a concerted effort to forge a higher-level synthesis. However, in engaging agency/ practice and evolution in Chap. 2, we are not reticent to point out conflicts between Behavioral Archaeology and these programs. This book will appeal to archaeologists and anthropologists as well as historians, sociologists, and philosophers of technology. Those who study science¿technology¿ society interactions may also encounter useful ideas. Finally, this book is suitable for upper-division and graduate courses on anthropological theory, archaeological theory, and the study of technology.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 188 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -This introductory text deals with the physical systems and biological processes that intervene in what we broadly call ¿music. ¿ We shall analyze what obj- tive, physical properties of sound patterns are associated with what subjective, psychological sensations of music. We shall describe how these sound patterns are actually produced in musical instruments, how they propagate through the environment, and how they are detected by the ear and interpreted in the brain. We shall do all this by using the physicist¿s language and his method of thought and analysis¿without, however, using complicated mathematics. Although no previous knowledge of physics, physiology, and neurobiology is required, it is assumedthatthereaderpossesseshigh-schooleducationandisfamiliarwit hbasic aspects of music, in particular with musical notation, scales and intervals, musical instruments and typical musical ¿sensations. ¿ Books are readily available on the fundamentals of physics of music (e. g. , Benade, 1990; Pierce, 1983; Fletcher and Rossing, 1998; Johnston, 2003) and psychoacoustics, music psychology and perception (e. g. , Plomp, 1976; Deutsch, 1982a; Zatorre and Peretz, 2001; Hartmann, 2005). An excellent text on musical acoustics is that of Sundberg (1991), still most useful 17 years later; comp- hensive discussions of recent researches on pitch perception and related au- tory mechanisms can be found in Plack et al. (2005). The purpose of the present volume is not to duplicate but to synthesize and complement existing literature.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 244 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -There has been a long history of interaction between mathematics and physiology. This book looks in detail at a wide selection of mathematical models in physiology, showing how physiological problems can be formulated and studied mathematically, and how such models give rise to interesting and challenging mathematical questions. With its coverage of many recent models it gives an overview of the field, while many older models are also discussed, to put the modern work in context.In this second edition the coverage of basic principles has been expanded to include such topics as stochastic differential equations, Markov models and Gibbs free energy, and the selection of models has also been expanded to include some of the basic models of fluid transport, respiration/perfusion, blood diseases, molecular motors, smooth muscle, neuroendrocine cells, the baroreceptor loop, turboglomerular oscillations, blood clotting and the retina.Owing to this extensive coverage, the seond edition is published in two volumes. This first volume deals with the fundamental principles of cell physiology and the second with the physiology of systems.The book includes detailed illustrations and numerous excercises with selected solutions. The emphasis throughout is on the applications; because of this interdisciplinary approach, this book will be of interest to students and researchers, not only in mathematics, but also in bioengineering, physics, chemistry, biology, statistics and medicine.James Keener is a Distinguished Professor of Mathematics at the University of Utah.James Sneyd is the Professor of Applied Mathematics at the University of Auckland, New Zealand. He is best known for his work on the dynamics of intracellular calcium.Reviews of the first edition:.probably the best book ever written on the interdisciplinary field of mathematical physiology. Mathematical Reviews, 2000In addition to being good reading, excellent pedagogy, and appealing science, the exposition is lucid and clear, and there are many good problem sets to choose from. Highly recommended. Mathematical Biosciences, 1999Both authors are seasoned experts in the field of mathematical physiology and particularly in the field of excitability, calcium dynamics and spiral waves. It directs students to become not merely skilled technicians in biological research but masters of the science. SIAM, 2004The first edition was the winner of the prize for The Best Mathematics book of 1998 from the American Association of Publishers.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 608 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -Intended to follow the usual introductory physics courses, this book has the unique feature of addressing the mathematical needs of sophomores and juniors in physics, engineering and other related fields. Many original, lucid, and relevant examples from the physical sciences, problems at the ends of chapters, and boxes to emphasize important concepts help guide the student through the material.Beginning with reviews of vector algebra and differential and integral calculus, the book continues with infinite series, vector analysis, complex algebra and analysis, ordinary and partial differential equations. Discussions of numerical analysis, nonlinear dynamics and chaos, and the Dirac delta function provide an introduction to modern topics in mathematical physics.This new edition has been made more user-friendly through organization into convenient, shorter chapters. Also, it includes an entirely new section on Probability and plenty of new material on tensors and integral transforms.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 860 pp. Englisch.

Buch. Zustand: Neu. Neuware -Divided into two volumes, the book begins with a pedagogical presentation of some of the basic theory, with chapters on biochemical reactions, diffusion, excitability, wave propagation and cellular homeostasis. The second, more extensive part discusses particular physiological systems, with chapters on calcium dynamics, bursting oscillations and secretion, cardiac cells, muscles, intercellular communication, the circulatory system, the immune system, wound healing, the respiratory system, the visual system, hormone physiology, renal physiology, digestion, the visual system and hearing.New chapters on Calcium Dynamics, Neuroendocrine Cells and Regulation of Cell Function have been included.Reviews from first edition:Keener and Sneyd's Mathematical Physiology is the first comprehensive text of its kind that deals exclusively with the interplay between mathematics and physiology. Writing a book like this is an audacious act!Society of Mathematical BiologyKeener and Sneyd's is unique in that it attempts to present one of the most important subfields of biology and medicine, physiology, in terms of mathematical 'language', rather than organizing materials around mathematical methodology.SIAM reviewSpringer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 576 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -Box 9E. 1 Continued FIGURE 2. The C¿S¿R triangle model (Grime 1979). The strategies at the three corners are C, competiti- winning species; S, stress-tolerating s- cies; R,ruderalspecies. Particular species can engage in any mixture of these three primary strategies, and the m- ture is described by their position within the triangle. comment briefly on some other dimensions that Grime¿s (1977) triangle (Fig. 2) (see also Sects. 6. 1 are not yet so well understood. and 6. 3 of Chapter 7 on growth and allocation) is a two-dimensional scheme. A C¿S axis (Com- tition-winning species to Stress-tolerating spe- Leaf Economics Spectrum cies) reflects adaptation to favorable vs. unfavorable sites for plant growth, and an R- Five traits that are coordinated across species are axis (Ruderal species) reflects adaptation to leaf mass per area (LMA), leaf life-span, leaf N disturbance. concentration, and potential photosynthesis and dark respiration on a mass basis. In the five-trait Trait-Dimensions space,79%ofallvariation worldwideliesalonga single main axis (Fig. 33 of Chapter 2A on photo- A recent trend in plant strategy thinking has synthesis; Wright et al. 2004). Species with low been trait-dimensions, that is, spectra of varia- LMA tend to have short leaf life-spans, high leaf tion with respect to measurable traits. Compared nutrient concentrations, and high potential rates of mass-based photosynthesis. These species with category schemes, such as Raunkiaer¿s, trait occur at the ¿¿quick-return¿¿ end of the leaf e- dimensions have the merit of capturing cont- nomics spectrum.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 636 pp. Englisch.

Buch. Zustand: Neu. Neuware -Academic research on developed countries has scientifically evaluated the role of entrepreneurship on economic growth, market expansion, commercializing innovation, and reducing unemployment. In this research, regions or industries with higher rates of entrepreneurship show higher levels of innovation and economic growth. The literature on entrepreneurship and innovation has largely ignored developing countries, despite the positive results from new venture investments in India, China, and elsewhere. This volume bridges this gap by bringing together research by scholars in Germany and India, whose analysis of entrepreneurship, innovation, and economic development in their respective countries reveals commonalities. Covering such timely issues as R&D and labor policies and including case examples from the chemical, biotech, and IT industries, the authors offer insight into the entrepreneurial process. The volume concludes with a discussion of the global implications for entrepreneurship research and policy.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 236 pp. Englisch.

Buch. Zustand: Neu. Neuware -The extreme exibility of recon gurable architectures and their performance pot- tial have made them a vehicle of choice in a wide range of computing domains, from rapid circuit prototyping to high-performance computing. The increasing availab- ity of transistors on a die has allowed the emergence of recon gurable architectures with a large number of computing resources and interconnection topologies. To - ploit the potential of these recon gurable architectures, programmers are forced to map their applications, typically written in high-level imperative programming l- guages, such as C or MATLAB, to hardware-oriented languages such as VHDL or Verilog. In this process, they must assume the role of hardware designers and software programmers and navigate a maze of program transformations, mapping, and synthesis steps to produce ef cient recon gurable computing implementations. The richness and sophistication of any of these application mapping steps make the mapping of computations to these architectures an increasingly daunting process. It is thus widely believed that automatic compilation from high-level programming languages is the key to the success of recon gurable computing. This book describes a wide range of code transformations and mapping te- niques for programs described in high-level programming languages, most - tably imperative languages, to recon gurable architectures.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 236 pp. Englisch.

Buch. Zustand: Neu. Neuware -The subject for this book is my life work on the enterprise modeling and integration by a stochastic/queuing form, and the book plan was conceived before my stay in the USA in 1996¿97 as a visiting scholar. The rst title was ¿Stochastic Management and Design of Manufacturing Systems.¿ The rst version was attempted in 2001; however, this version was inappropriate and was not revised till now. It is 40 years since I attempted a stochastic approach to manufacturing and management due to the limitations of statistical approaches. The century in which industrial engineering and management rose to the forefront was one in which a static/statistical approach was applied to the development of classical models and general/average theory. This book presents a stochastic management approach to the manufacturing and service enterprise with risks by a game/strategic view, and is based on many papers in production/queueing studies that have appeared in famous journals. The book¿s objective is to discuss and show the goals and constraints on manufacturing and service enterprises, and to provide a strategic/collaborative solution for management with risks in heterogeneity. This book mainly focuses on the three manufacturing classes: continuous, poi- wise, and exible stream types under risks. These manufacturing streams are rst studied using the respective stochastic processes, and are characterized and dev- oped as a queueing/strategic control problem of look-ahead/buffer, selection/swit- over, and arrangement/routings. Moreover, the behaviors of some design/control variables are shown and useful theories for design are established.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 296 pp. Englisch.

Buch. Zustand: Neu. Neuware -Putting Crime in its Place: Units of Analysis in Geographic Criminology focuses on the units of analysis used in geographic criminology. While crime and place studies have been a part of criminology from the early 19th century, growing interest in crime places over the last two decades demands critical reflection on the units of analysis that should form the focus of geographic analysis of crime. Should the focus be on very small units such as street addresses or street segments, or on larger aggregates such as census tracts or communities Academic researchers, as well as practical crime analysts, are confronted routinely with the dilemma of deciding what the unit of analysis should be when reporting on trends in crime, when identifying crime hot spots or when mapping crime in cities. In place-based crime prevention, the choice of the level of aggregation plays a particularly critical role. This peer reviewed collection of essays aims to contribute to crime and place studies by making explicit the problems involved in choosing units of analysis in geographic criminology. Written by renowned experts in the field, the chapters in this book address basic academic questions, and also provide real-life examples and applications of how they are resolved in cutting-edge research. Crime analysts in police and law enforcement agencies as well as academic researchers studying the spatial distributions of crime and victimization will learn from the discussions and tools presented.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 272 pp. Englisch.

Buch. Zustand: Neu. Neuware -Recent advances in both the theory and implementation of computational algebraic geometry have led to new, striking applications to a variety of fields of research. The articles in this volume highlight a range of these applications and provide introductory material for topics covered in the IMA workshops on 'Optimization and Control' and 'Applications in Biology, Dynamics, and Statistics' held during the IMA year on Applications of Algebraic Geometry. The articles related to optimization and control focus on burgeoning use of semidefinite programming and moment matrix techniques in computational real algebraic geometry. The new direction towards a systematic study of non-commutative real algebraic geometry is well represented in the volume. Other articles provide an overview of the way computational algebra is useful for analysis of contingency tables, reconstruction of phylogenetic trees, and in systems biology. The contributions collected in this volume are accessible to non-experts, self-contained and informative; they quickly move towards cutting edge research in these areas, and provide a wealth of open problems for future research.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 392 pp. Englisch.

Buch. Zustand: Neu. Neuware -Things have changed. In 1969 when the Convention for the Conservation of the Vicuña was drafted, in an attempt to save the vicuña from its tumbling decline towards extinction, both the science and the philosophy of wildlife conservation were radically different. It is thus a tribute to the prescience of those involved at the time that the rescue plan had, even through the harsh lens of hindsight, a d- tinctly Twenty First Century flavour. After all, it was predicated on the expectation that if vicuña could be saved, they would one day become a valued asset, generating revenue for the human communities that fostered their survival. Embodied in this aspiration are the main structures of modern biodiversity conservation ¿ not only is it to be underpinned by science, but that science should be of both the natural and the social genres, woven into inter-disciplinarity, and thereby taking heed of e- nomics, governance, ownership and the like, alongside biology. In addition, it should include, as a major strut, the human dimension, taking account of the affected constituencies with their varied stakes in alternative outcomes. This c- temporary framework for thinking about biodiversity conservation is inseparable from such wider, and inherently political, notions as community-based conser- tion and ultimately sustainable use.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 136 pp. Englisch.

Buch. Zustand: Neu. Neuware -Heterogeneous wireless networking, which is sometimes referred to as the fourth-generation (4G) wireless, is a new frontier in the future wireless communications technology and there has been a growing interest on this topic among researchers and engineers in both academia and industry. This book will include a set of research and survey articles featuring the recent advances in theory and applications of heterogeneous wireless networking technology for the next generation (e.g., fourth generation) wireless communications systems. With the rapid growth in the number of wireless applications, services and devices, using a single wireless technology such as a second generation (2G) and third generation (3G) wireless system would not be efficient to deliver high speed data rate and quality-of-service (QoS) support to mobile users in a seamless way. Fourth generation (4G) wireless systems are devised with the vision of heterogeneity in which a mobile user/device will be able to connect to multiple wireless networks (e.g., WLAN, cellular, WMAN) simultaneously. This book intends to provide a unified view on the state-of-the-art of protocols and architectures for heterogeneous wireless networking. The contributed articles will cover both the theoretical concepts and system-level implementation issues related to design, analysis, and optimization of architectures and protocols for heterogeneous wireless access networks.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 492 pp. Englisch.

Buch. Zustand: Neu. Neuware -One important reason for the multitude of research activities in this field is because physical inactivity and nutrition are significant risk factors for many common non-communicable diseases. During the past decades physical inactivity and high dietary fat intakes have become increasingly prevalent in people¿s daily lives in industrialised countries. To prevent and to tackle these major diseases, there is a need for a much better understanding of the basic biological and underlying patho-physiological processes, as well as more relevant baseline data describing food intakes and physical activity habits amongst the general population.Being aware of the importance of nutrition and physical activity for health status a multitude of projects with different scopes and methodologies has arisen. This variety makes it necessary to bring the results of these activities into a coordinated framework.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 604 pp. Englisch.

Buch. Zustand: Neu. Neuware -Solder Joint Reliability Prediction for Multiple Environments will provide industry engineers, graduate students and academic researchers, and reliability experts with insights and useful tools for evaluating solder joint reliability of ceramic area array electronic packages under multiple environments. The material presented here is not limited to ceramic area array packages only, it can also be used as a methodology for relating numerical simulations and experimental data into an easy-to-use equation that captures the essential information needed to predict solder joint reliability. Such a methodology is often needed to relate complex information in a simple manner to managers and non-experts in solder joint who work with computer server applications as well as for harsh environments such as those found in the defense, space, and automotive industries.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 212 pp. Englisch.

Buch. Zustand: Neu. Neuware -¿Sensors Based on Nanostructured Materials¿ presents the many different techniques and methods of fabricating materials on the nanometer scale, and, specifically, the utilization of these resources with regard to sensors. The techniques which are described are studied from an application-oriented perspective, providing the reader with a broader perspective of the types of nanostructured sensors available than other books which concentrate on theoretical situations related to specific fabrication techniques. Rather than focus on possible techniques for future fabrication, this book describes and explores well established techniques for fabricating sensors using nanostructured materials, and serves as a multidisciplinary text which considers the uses in optics, electronics, and biochemistry.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 340 pp. Englisch.

Buch. Zustand: Neu. Neuware -Solid State Gas Sensing offers insight into the principles, applications, and new trends in gas sensor technology. Developments in this field are rapidly advancing due to the recent and continuing impact of nanotechnology, and this book addresses the demand for small, reliable, inexpensive and portable systems for monitoring environmental concerns, indoor air quality, food quality, and many other specific applications. Working principles, including electrical, permittivity, field effect, electrochemical, optical, thermometric and mass (both quartz and cantilever types), are discussed, making the book valuable and accessible to a variety of researchers and engineers in the field of material science.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 356 pp. Englisch.

Buch. Zustand: Neu. Neuware -Intended to follow the usual introductory physics courses, this book has the unique feature of addressing the mathematical needs of sophomores and juniors in physics, engineering and other related fields. Many original, lucid, and relevant examples from the physical sciences, problems at the ends of chapters, and boxes to emphasize important concepts help guide the student through the material.Beginning with reviews of vector algebra and differential and integral calculus, the book continues with infinite series, vector analysis, complex algebra and analysis, ordinary and partial differential equations. Discussions of numerical analysis, nonlinear dynamics and chaos, and the Dirac delta function provide an introduction to modern topics in mathematical physics.This new edition has been made more user-friendly through organization into convenient, shorter chapters. Also, it includes an entirely new section on Probability and plenty of new material on tensors and integral transforms.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 860 pp. Englisch.

Buch. Zustand: Neu. Neuware -There has been a long history of interaction between mathematics and physiology. This book looks in detail at a wide selection of mathematical models in physiology, showing how physiological problems can be formulated and studied mathematically, and how such models give rise to interesting and challenging mathematical questions. With its coverage of many recent models it gives an overview of the field, while many older models are also discussed, to put the modern work in context.In this second edition the coverage of basic principles has been expanded to include such topics as stochastic differential equations, Markov models and Gibbs free energy, and the selection of models has also been expanded to include some of the basic models of fluid transport, respiration/perfusion, blood diseases, molecular motors, smooth muscle, neuroendrocine cells, the baroreceptor loop, turboglomerular oscillations, blood clotting and the retina.Owing to this extensive coverage, the seond edition is published in two volumes. This first volume deals with the fundamental principles of cell physiology and the second with the physiology of systems.The book includes detailed illustrations and numerous excercises with selected solutions. The emphasis throughout is on the applications; because of this interdisciplinary approach, this book will be of interest to students and researchers, not only in mathematics, but also in bioengineering, physics, chemistry, biology, statistics and medicine.James Keener is a Distinguished Professor of Mathematics at the University of Utah.James Sneyd is the Professor of Applied Mathematics at the University of Auckland, New Zealand. He is best known for his work on the dynamics of intracellular calcium.Reviews of the first edition:.probably the best book ever written on the interdisciplinary field of mathematical physiology. Mathematical Reviews, 2000In addition to being good reading, excellent pedagogy, and appealing science, the exposition is lucid and clear, and there are many good problem sets to choose from. Highly recommended. Mathematical Biosciences, 1999Both authors are seasoned experts in the field of mathematical physiology and particularly in the field of excitability, calcium dynamics and spiral waves. It directs students to become not merely skilled technicians in biological research but masters of the science. SIAM, 2004The first edition was the winner of the prize for The Best Mathematics book of 1998 from the American Association of Publishers.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 608 pp. Englisch.

Buch. Zustand: Neu. Neuware -Food safety awareness is at an all time high, new and emerging threats to the food supply are being recognized, and consumers are eating more and more meals prepared outside of the home. Accordingly, retail and foodservice establishments, as well as food producers at all levels of the food production chain, have a growing responsibility to ensure that proper food safety and sanitation practices are followed, thereby, safeguarding the health of their guests and customers.Achieving food safety success in this changing environment requires going beyond traditional training, testing, and inspectional approaches to managing risks. It requires a better understanding of organizational culture and the human dimensions of food safety. To improve the food safety performance of a retail or foodservice establishment, an organization with thousands of employees, or a local community, you must change the way people do things. You must change their behavior. In fact, simply put,food safety equals behavior. When viewed from these lenses, one of the most common contributing causes of food borne disease is unsafe behavior (such as improper hand washing, cross-contamination, or undercooking food). Thus, to improve food safety, we need to better integrate food science with behavioral science and use a systems-based approach to managing food safety risk.The importance of organizational culture, human behavior, and systems thinking is well documented in the occupational safety and health fields. However, significant contributions to the scientific literature on these topics are noticeably absent in the field of food safety.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 112 pp. Englisch.

Buch. Zustand: Neu. Neuware -A sense of belonging is basic to the human experience. But in this, humans are not unique. Essentially all life, from bacteria to humans, have ways by which it determines which members belong and which do not. This is a basic cooperative nature of life I call group membership which is examined in this book. However, cooperation of living things is not easily accounted for by current theory of evolutionary biology and yet even viruses display group membership. That viruses have this feature would likely seem coincidental or irrelevant to most scientist as having any possible relationship to human group identity. Surely such simple molecular-based relationships between viruses are unrelated to the complex cognitive and emotional nature of human group membership. Yet viruses clearly affect bacterial group membership, which are the most diverse and abundant cellular life form on Earth and from which all life has evolved. Viruses are the most ancient, numerous and adaptable biological entities we know. And we have long recognized them for the harm and disease they can cause, and they have been responsible for the greatest numbers of human deaths. However, with the sequencing of entire genomes and more recently with the shotgun sequencings of habitats, we have come to realize viruses are the black hole of biology; a giant force that has until recently been largely unseen and historically ignored by evolutionary biology. Viruses not only can cause acute disease, but also persist as stable unseen agents in their host.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 652 pp. Englisch.

Buch. Zustand: Neu. Neuware -Reviews of Environmental Contamination and Toxicology attempts to provide concise, critical reviews of timely advances, philosophy and significant areas of accomplished or needed endeavor in the total field of xenobiotics, in any segment of the environment, as well as toxicological implications.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 208 pp. Englisch.

Buch. Zustand: Neu. Neuware -Innate immunity is one the most evolutionally conserved systems, designed to protect the organism from viruses and bacterial infections, stress and many other types of attacks from the outside world. During the past decade, the capacity of molecular biology and information technology to produce and analyse data have grown exponentially, rapidly reforming many aspects of immunology research in the post-genomics era. As a result, scientific understanding of signalling networks governing the innate immunity response in human tissues and other organisms has evolved beyond recognition, compared to even just a decade ago. Many strategies have been designed over the years to identify novel proteins, which have a crucial role in innate immunity responses by regulating particular signalling pathways. These projects had many advantages, including the definition of novel drug targets, as exemplified by the recent success of anti-TNF therapy, as well as leading to a better, system-wide understanding of the molecular control of innate immunity. In the past few years, a new concept, Immunomics, has been adopted to define an emerging, multidisciplinary field of research (Schonbach, 2003). Although rapid progress has been made to identify the proteins playing pivotal roles in the innate immunity¿related signalling pathways (for example, TIR signalling pathways), the catalogue of proteins with a key regulatory function identified and studied is far from completed. Novel proteins need to be char- terised to gain a more comprehensive picture of how signalling networks are regulated.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 300 pp. Englisch.

Buch. Zustand: Neu. Neuware -A major process of rediscovery has taken place in the eld of Cellular Immunology over the past 12 years¿subsets of T lymphocytes exist that are speci cally d- icated to regulation or as it should be more appropriately termed suppression of all aspects of immune responses. It is certainly appropriate at this time to recall some of the history that lead to the development of the concept of immune r- ulation/suppression. Shortly after the term helper T cells was coined to described lymphocytes that ¿helped¿ both humoral and cell-mediated responses, studies from thelaboratoryofthe lateProfessorRichardGershondemonstratedthatundercertain conditions, antigen recognition by T lymphocytes also resulted in the development of cells that are able to suppress immune responses. Unfortunately, research in this eld rapidly shifted from studies of the function of the suppressor T cells to studies of their soluble products that were thought to be shed or secreted T cell receptors. A number of highly complex suppressor cell pathways and cell circuits were dev- opedand werethe subjectsof morethan5,000papersduringthisera. In 1983¿1984, this eld completelycollapsed as studies called into question the existence of the I-J region of the mouse major histocompatibility complex that was thought to encode one of the major chains of the suppressor T cell factors.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 624 pp. Englisch.

Buch. Zustand: Neu. Neuware -Classical circuit theory is a mathematical theory of linear, passive circuits, namely, circuits composed of resistors, capacitors and inductors. Like many a thing classical, it is old and enduring, structured and precise, simple and elegant. It is simple in that everything in it can be deduced from rst principles based on a few physical laws. It is enduring in that the things we can say about linear, passive circuits are universally true, unchanging. No matter how complex a circuit may be, as long as it consists of these three kinds of elements, its behavior must be as prescribed by the theory. The theory tells us what circuits can and cannot do. As expected of any good theory, classical circuit theory is also useful. Its ulti mate application is circuit design. The theory leads us to a design methodology that is systematic and precise. It is based on just two fundamental theorems: that the impedance function of a linear, passive circuit is a positive real function, and that the transfer function is a bounded real function, of a complex variable.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 312 pp. Englisch.

Buch. Zustand: Neu. Neuware -Humans have always been fascinated by marine life, from extremely small diatoms to the largest mammal that inhabits our planet, the blue whale. However, studying marine life in the ocean is an extremely difficult propo- tion because an ocean environment is not only vast but also opaque to most instruments and can be a hostile environment in which to perform expe- ments and research. The use of acoustics is one way to effectively study animal life in the ocean. Acoustic energy propagates in water more efficiently than almost any form of energy and can be utilized by animals for a variety of purposes and also by scientists interested in studying their behavior and natural history. However, underwater acoustics have traditionally been in the domain of physicists, engineers and mathematicians. Studying the natural history of animals is in the domain of biologists and physiologists. Und- standing behavior of animals has traditionally involved psychologists and zoologists. In short, marine bioacoustics is and will continue to be a diverse discipline involving investigators from a variety of backgrounds, with very different knowledge and skill sets. The inherent inter-disciplinary nature of marine bioacoustics presents a large challenge in writing a single text that would be meaningful to various investigators and students interested in this field. Yet we have embarked on this challenge to produce a volume that would be helpful to not only beginning investigators but to seasoned researchers.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 696 pp. Englisch.