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  • Buch 15 von 69: Statistics for Biology and Health

    Gregory R. Grant

    Sprache: Englisch

    Verlag: Springer US, Springer New York Dez 2004, 2004

    ISBN 10: 0387400826 ISBN 13: 9780387400822

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    Buch. Zustand: Neu. Neuware -Advances in computers and biotechnology have had a profound impact on biomedical research, and as a result complex data sets can now be generated to address extremely complex biological questions. Correspondingly, advances in the statistical methods necessary to analyze such data are following closely behind the advances in data generation methods. The statistical methods required by bioinformatics present many new and difficult problems for the research community.This book provides an introduction to some of these new methods. The main biological topics treated include sequence analysis, BLAST, microarray analysis, gene finding, and the analysis of evolutionary processes. The main statistical techniques covered include hypothesis testing and estimation, Poisson processes, Markov models and Hidden Markov models, and multiple testing methods.The second edition features new chapters on microarray analysis and on statistical inference, including a discussion of ANOVA, and discussions of the statistical theory of motifs and methods based on the hypergeometric distribution. Much material has been clarified and reorganized.The book is written so as to appeal to biologists and computer scientists who wish to know more about the statistical methods of the field, as well as to trained statisticians who wish to become involved with bioinformatics. The earlier chapters introduce the concepts of probability and statistics at an elementary level, but with an emphasis on material relevant to later chapters and often not covered in standard introductory texts. Later chapters should be immediately accessible to the trained statistician. Sufficient mathematical background consists of introductory courses in calculus and linear algebra. The basic biological concepts that are used are explained, or can be understood from the context, and standard mathematical concepts are summarized in an Appendix. Problems are provided at the end of each chapter allowing the reader to develop aspects of the theory outlined in the main text.Warren J. Ewens holds the Christopher H. Brown Distinguished Professorship at the University of Pennsylvania. He is the author of two books, Population Genetics and Mathematical Population Genetics. He is a senior editor of Annals of Human Genetics and has served on the editorial boards of Theoretical Population Biology, GENETICS, Proceedings of the Royal Society B and SIAM Journal in Mathematical Biology. He is a fellow of the Royal Society and the Australian Academy of Science.Gregory R. Grant is a senior bioinformatics researcher in the University of Pennsylvania Computational Biology and Informatics Laboratory. He obtained his Ph.D. in number theory from the University of Maryland in 1995 and his Masters in Computer Science from the University of Pennsylvania in 1999.Comments on the first edition:'This book would be an ideal text for a postgraduate course¿[and] is equally well suited to individual study¿. I would recommend the book highly.' (Biometrics)'Ewens and Grant have given us a very welcome introduction to what is behind those pretty [graphical user] interfaces.' (Naturwissenschaften)'The authors do an excellent job of presenting the essence of the material without getting bogged down in mathematical details.' (Journal American Statistical Association)'The authors have restructured classical material to a great extent and the new organization of the different topics is one of the outstanding services of the book.' (Metrika)Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 620 pp. Englisch.

  • Bernd Sturmfels

    Sprache: Englisch

    Verlag: Springer New York, Springer US Dez 2004, 2004

    ISBN 10: 0387223568 ISBN 13: 9780387223568

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    Buch. Zustand: Neu. Neuware -Combinatorial commutative algebra is an active area of research with thriving connections to other fields of pure and applied mathematics. This book provides a self-contained introduction to the subject, with an emphasis on combinatorial techniques for multigraded polynomial rings, semigroup algebras, and determinantal rings. The eighteen chapters cover a broad spectrum of topics, ranging from homological invariants of monomial ideals and their polyhedral resolutions, to hands-on tools for studying algebraic varieties with group actions, such as toric varieties, flag varieties, quiver loci, and Hilbert schemes. Over 100 figures, 250 exercises, and pointers to the literature make this book appealing to both graduate students and researchers.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 436 pp. Englisch.

  • Narottam P. Bansal

    Sprache: Englisch

    Verlag: Springer US, Springer New York Dez 2004, 2004

    ISBN 10: 1402081332 ISBN 13: 9781402081330

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    Buch. Zustand: Neu. Neuware -Ceramic matrix composites (CMCs) are at the forefront of advanced materials technology because of their light weight, high strength and toughness, high temperature capabilities, and graceful failure under loading. During the last 25 years, tremendous progress has been made in the development and advancement of CMCs under various research programs funded by the U.S. Government agencies: National Aeronautics and Space Administration (NASA), Department of Defense (DoD), and Department of Energy (DOE).Ceramic composites are considered as enabling technology for advanced aeropropulsion, space propulsion, space power, aerospace vehicles, and space structures. CMCs would also find applications in advanced aerojet engines, stationary gas turbines for electrical power generation, heat exchangers, hot gas filters, radiant burners, heat treatment and materials growth furnaces, nuclear fusion reactors, automobiles, biological implants, etc. Other applications of CMCs are as machinery wear parts, cutting and forming tools, valve seals, high precision ball bearings for corrosive environments, and plungers for chemical pumps. Potential applications of various ceramic composites are described in individual chapters of the present handbook.Handbook of Ceramic Composites is different from the other books available on this topic. Here, a ceramic composite system or a class of composites has been covered in a separate chapter, presenting a detailed description of processing, properties, and applications. Each chapter is written by internationally renowned researchers in the field. The handbook is organized into five sections: Ceramic Fibers, Non-oxide/Non-oxide Composites, Non-oxide/Oxide Composites, Oxide/Oxide Composites, and Glass and Glass-Ceramic Composites.This handbook should be a valuable source of information for scientists, engineers, and technicians working in the field of CMCs, and also for designers to design parts and components for advanced engines, and various other industrial applications.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 568 pp. Englisch.

  • Howard Kunreuther

    Sprache: Englisch

    Verlag: Springer US, Springer New York Dez 2004, 2004

    ISBN 10: 0387230823 ISBN 13: 9780387230825

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    Buch. Zustand: Neu. Neuware -Catastrophe Modeling: A New Approach to Managing Risk is the first book that systematically analyzes how catastrophe models can be used for assessing and managing risks of extreme events. It focuses on natural disaster risk, but also discusses the management of terrorism risk. A unique feature of this book is the involvement of three leading catastrophe modeling firms, AIR Worldwide, EQECAT, and Risk Management Solutions, who examine the role of catastrophe modeling in rate setting, portfolio management and risk financing.Using data from three model cities (Oakland, CA, Long Beach, CA and Miami/Dade County, FLA), experts from the Wharton School of the University of Pennsylvania examine the role of catastrophe modeling to develop risk management strategies for reducing and spreading the losses from future disasters. Given the uncertainties associated with terrorism the book points out the opportunities for utilizing catastrophe models to set insurance rates and to examine public-private partnerships for providing financial assistance in the event of a terrorist attack.'This book fills a critical need in setting forth the role of modern risk analysis in managing catastrophe risk. There is no comparable reference work for this important subject area. The book is well written and well organized. It contains contributions from many of the most distinguished experts in the fields of risk analysis and risk management. It strikes a good balance between the technical aspects of the subject and the practical aspects of decision making.''This book is strongly recommended for individuals who must make decisions regarding the management of impacts of catastrophe risks including those in both the public and private sector.'Wilfred D. IwanProfessor of Applied Mechanics, EmeritusDirector, Earthquake Engineering Research LaboratoryCalifornia Institute of Technology'The authors have captured the essence of catastrophe modeling: its value, its utility and its limitations. Every practitioner in the catastrophe risk field should read this book.'Franklin W. Nutter, PresidentReinsurance Association of AmericaSpringer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 268 pp. Englisch.

  • Richard A. Hopkins

    Sprache: Englisch

    Verlag: Springer New York, Springer US Dez 2004, 2004

    ISBN 10: 0387949623 ISBN 13: 9780387949628

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    Buch. Zustand: Neu. Xenakis, T. (illustrator). Neuware -Cryopreserved allograft tissues are now standard materials for the reconstructive cardiac surgeon. Since publication of the first edition ('Cardiac Reconstructions with Allograft Valves') in 1989, the field has progressed dramatically with increased clinical use of cardiovascular allograft tissues, with the development of new surgical techniques, and with advances in the understanding of the fundamentals of valve transplantation biology and cryopreservation. As a result, over two-thirds of the present volume represents new material. Fifty-six authors bring their expertise to thirteen comprehensive, lavishly illustrated sections which discuss the principles of the use of homograft valves, major clinical series of homograft valves for both left and right ventricular outflow tracts, cryopreserved allograft tissue for cardiac reconstruction, cell biology of heart valve leaflets, cryobiology of heart valve preservation, morphological, biochemical, and explant pathology studies of allograft heart valves, allograft valve banking, as well as detailed explanation of surgical techniques for valve and root methods for left and right ventricular outflow tract reconstructions, the Ross operation and variants, and complex reconstructions. A final section presents potential future directions for the field. Over 400 illustrations, created expressly for this book, depict the surgical techniques from the perspective of the surgeon standing at the operating table. All surgeons performing pediatric and/or adult valve replacements and reconstructive cardiac surgeries will benefit from the described methods. Cardiothoracic residents and cardiologists will also find the text useful. It will provide the surgeon with an enhanced understanding of the biological and material properties of allografts and increased familiarity with the range of surgical techniques applicable for the use of these valves, particularly in the successful management of challenging cardiac reconstructions.>Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 684 pp. Englisch.

  • Michael A. Crew

    Sprache: Englisch

    Verlag: Springer US, Springer New York Dez 2004, 2004

    ISBN 10: 1402079729 ISBN 13: 9781402079726

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Buch. Zustand: Neu. Neuware -Worldwide, there is considerable interest in postal and delivery economics. Governments, particularly in the European Union, are examining closely the roles of the two systems and how best to regulate them. This volume brings together 20 essays originally presented at the 12th Conference on Postal and Delivery Economics held in Cork, Ireland in June 2004. Contributors include researchers, practitioners, and senior managers from throughout the world.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 432 pp. Englisch.

  • Steven T. Cundiff

    Sprache: Englisch

    Verlag: Springer US, Springer New York Dez 2004, 2004

    ISBN 10: 0387237909 ISBN 13: 9780387237909

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    Buch. Zustand: Neu. Neuware -Over the last few years, there has been a convergence between the fields of ultrafast science, nonlinear optics, optical frequency metrology, and precision laser spectroscopy. These fields have been developing largely independently since the birth of the laser, reaching remarkable levels of performance. On the ultrafast frontier, pulses of only a few cycles long have been produced, while in optical spectroscopy, the precision and resolution have reached one part in Although these two achievements appear to be completely disconnected, advances in nonlinear optics provided the essential link between them. The resulting convergence has enabled unprecedented advances in the control of the electric field of the pulses produced by femtosecond mode-locked lasers. The corresponding spectrum consists of a comb of sharp spectral lines with well-defined frequencies. These new techniques and capabilities are generally known as ¿femtosecond comb technology. ¿ They have had dramatic impact on the diverse fields of precision measurement and extreme nonlinear optical physics. The historical background for these developments is provided in the Foreword by two of the pioneers of laser spectroscopy, John Hall and Theodor Hänsch. Indeed the developments described in this book were foreshadowed by Hänsch¿s early work in the 1970s when he used picosecond pulses to demonstrate the connection between the time and frequency domains in laser spectroscopy. This work complemented the advances in precision laser stabilization developed by Hall.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 376 pp. Englisch.

  • Eiji Arai

    Sprache: Englisch

    Verlag: Springer US, Springer New York Dez 2004, 2004

    ISBN 10: 0387238514 ISBN 13: 9780387238517

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    Buch. Zustand: Neu. Neuware -Since the first DIISM conference, which took place 9 years ago, the world has seen drastic changes, including the transformation of manufacturing and engineering software, and the information and communication technologies deployed. The conditions for manufacturing and engineering have changed on a large scale, in terms of technology-enabled collaboration among the fields of design, engineering, production, usage, maintenance and recyclingldisposal. These changes can be observed in rapidly-growing fields such as supply chain management. As for production technologies at factory floors, new visions on human-machine co-existing systems involve both knowledge management and multi-media technologies. Therefore, because of these changes, the importance of information infrastructure for manufacturing has increased, stunningly. Information infrastructure plays a key role in integrating diverse fields of manufacturing, engineering and management. This, in addition to its basic role, as the information and communication platform for the production systems. Eventually, it should also serve the synthetic function of knowledge management, during the life cycles of both the production systems and their products, and for all stakeholders.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 392 pp. Englisch.

  • Paul Pop

    Sprache: Englisch

    Verlag: Springer US, Springer New York Dez 2004, 2004

    ISBN 10: 1402028725 ISBN 13: 9781402028724

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    Buch. Zustand: Neu. Neuware -Embedded computer systems are now everywhere: from alarm clocks to PDAs, from mobile phones to cars, almost all the devices we use are controlled by embedded computers. An important class of embedded computer systems is that of hard real-time systems, which have to fulfill strict timing requirements. As real-time systems become more complex, they are often implemented using distributed heterogeneous architectures.Analysis and Synthesis of Distributed Real-Time Embedded Systems addresses the design of real-time applications implemented using distributed heterogeneous architectures. The systems are heterogeneous not only in terms of hardware components, but also in terms of communication protocols and scheduling policies. Regarding this last aspect, time-driven and event-driven systems, as well as a combination of the two, are considered. Such systems are used in many application areas like automotive electronics, real-time multimedia, avionics, medical equipment, and factory systems. The proposed analysis and synthesis techniques derive optimized implementations that fulfill the imposed design constraints. An important part of the implementation process is the synthesis of the communication infrastructure, which has a significant impact on the overall system performance and cost.Analysis and Synthesis of Distributed Real-Time Embedded Systems considers the mapping and scheduling tasks within an incremental design process. To reduce the time-to-market of products, the design of real-time systems seldom starts from scratch. Typically, designers start from an already existing system, running certain applications, and the design problem is to implement new functionality on top of this system. Supporting such an incremental design process provides a high degree of flexibility, and can result in important reductions of design costs.Analysis and Synthesis of Distributed Real-Time Embedded Systems will be of interest to advanced undergraduates, graduate students, researchers and designers involved in the field of embedded systems.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 352 pp. Englisch.

  • Buch 38 von 54: Advanced Studies in Theoretical and Applied Econometrics

    Peter Tryfos

    Sprache: Englisch

    Verlag: Springer US, Springer New York Dez 2004, 2004

    ISBN 10: 1402028385 ISBN 13: 9781402028380

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    Buch. Zustand: Neu. Neuware -Astranger in academia cannot but be impressed by the apparent uniformity and precision of the methodology currently applied to the measurement of economic relationships. In scores of journal articles and other studies, a theoretical argument is typically presented to justify the position that a certain variable is related to certain other, possibly causal, variables. Regression or a related method is applied to a set of observations on these variables, and the conclusion often emerges that the causa,l variables are indeed 'significant' at a certain 'level,' thereby lending support to the theoretical argument-an argument presumably formulated independently of the observations. A variable may be declared significant (and few doubt that this does not mean important) at, say, the 0. 05 level, but not the 0. 01. The effects of the variables are calculated to many significant digits, and are often accompanied by intervals and forecasts of not quite obvious meaning but certainly of reassuring 'confidence. ' The uniformity is also evident in the many mathematically advanced text books of statistics and econometrics, and in their less rigorous introductory versions for students in economics or business. It is reflected in the tools of the profession: computer programs, from the generaiones addressed to the incidental researcher to the dedicated and sophisticated programs used by the experts, display the same terms and implement the same methodology. In short, there appears no visible alternative to the established methodol ogy and no sign of reservat ions concerning its validity.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 164 pp. Englisch.

  • Buch 69 von 260: The Springer International Series in Engineering and Computer Science

    Philip Robinson

    Sprache: Englisch

    Verlag: Springer US, Springer New York Dez 2004, 2004

    ISBN 10: 0387234616 ISBN 13: 9780387234618

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    Buch. Zustand: Neu. Neuware -Privacy, Security and Trust within the Context of Pervasive Computing is an edited volume based on a post workshop at the second international conference on Pervasive Computing. The workshop was held April18-23, 2004, in Vienna, Austria.The goal of the workshop was not to focus on specific, even novel mechanisms, but rather on the interfaces between mechanisms in different technical and social problem spaces. An investigation of the interfaces between the notions of context, privacy, security, and trust will result in a deeper understanding of the 'atomic' problems, leading to a more complete understanding of the social and technical issues in pervasive computing.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 184 pp. Englisch.

  • Buch 3 von 16: Monographs in Computer Science

    Mark Burgin

    Sprache: Englisch

    Verlag: Springer New York, Springer US Dez 2004, 2004

    ISBN 10: 0387955690 ISBN 13: 9780387955698

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    Buch. Zustand: Neu. Neuware -Super-Recursive Algorithms provides an accessible, focused examination of the theory of super-recursive algorithms and its ramifications for the computer industry, networks, artificial intelligence, embedded systems, and the Internet. The book demonstrates how these algorithms are more appropriate as mathematical models for modern computers, and how these algorithms present a better framework for computing methods in such areas as numerical analysis, array searching, and controlling and monitoring systems. In addition, a new practically-oriented perspective on the theory of algorithms, computation, and automata, as a whole, is developed. Problems of efficiency, software development, parallel and distributed processing, pervasive and emerging computation, computer architecture, machine learning, brain modeling, knowledge discovery, and intelligent systems are addressed. This clear exposition, motivated by numerous examples and illustrations, serves researchers and advanced students interested in theory of computation and algorithms.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 320 pp. Englisch.

  • Mike Ludwig

    Sprache: Englisch

    Verlag: Springer US, Springer New York Dez 2004, 2004

    ISBN 10: 0387229337 ISBN 13: 9780387229331

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    Buch. Zustand: Neu. Neuware -The transmission of the nervous impulse is always from the dendritic branches and the cell body to the axon or functional process. Every neuron, then, possesses a receptor apparatus, the body and the dendritic prolongations, an apparatus of emission, the axon, and the apparatus of distribution, the terminal arborization of the nerve fibers. I designated the foregoing principle: the theory of dynamic polarization (Cajal 1923). Ever since the beautiful drawings from Golgi and Cajal, we have been familiar with the organisation of neurones into dendritic, somatic and axonal compartments. Cajal proposed that these cellular compartments were specialised, resulting in his concept of ^dynamic polarisation'. He considered dendrites to be passive elements that simply transferred information from inputs to the soma. Since the discovery that dendrites of many neural populations release neuroactive substances and in doing so, alter neuronal output, it is now apparent that this theory requires qualification. This book presents recent developments in the neurophysiology of dendritic release of several chemical classes of transmitters in a number of different areas of the mammalian central nervous system. Once released from a neuron, these substances can act as neurotransmitters and/or neuromodulators, to autoregulate the original neuron, its synaptic inputs, and adjacent cells or, by volume transmission, to affect distant cells. In some systems, dendritic transmitter release is part independent of secretion from axon terminal signifying a selective control of the dendritic compartment.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 364 pp. Englisch.

  • Gianfranco Gambarelli

    Sprache: Englisch

    Verlag: Springer US, Springer New York Dez 2004, 2004

    ISBN 10: 1402029357 ISBN 13: 9781402029356

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    Buch. Zustand: Neu. Neuware -Essays on Cooperative Games collates selected contributions on Cooperative Games. The papers cover both theoretical aspects (Coalition Formation, Values, Simple Games and Dynamic Games) and applied aspects (in Finance, Production, Transportation and Market Games). A contribution on Minimax Theorem (by Ken Binmore) and a brief history of early Game Theory (by Gianfranco Gambarelli and Guillermo Owen) are also enclosed.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 252 pp. Englisch.

  • John Edgar Park

    Sprache: Englisch

    Verlag: Springer New York, Springer US Dez 2004, 2004

    ISBN 10: 038700176X ISBN 13: 9780387001760

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    Taschenbuch. Zustand: Neu. Neuware -Many animators and designers would like to supplement their Mayalearning with a less-technical, more helpful book. This self-study manual is both a general guide for understanding 3-D computer graphics and a specific guide for learning the fundamentals of Maya: workspace, modeling, animation, shading, lighting, and rendering.Understanding 3-D Animation Using Maya covers these fundamentals in each chapter so that readers gain increasingly detailed knowledge. After an initial 'concepts' section launches each chapter, hands-on tutorials are provided, as well as a chapter project that progressively adds newly learned material and culminates in the final animated short. This is the first book on Maya that teaches the subject using a sensible, proven methodology for both novices and intermediate users.Topics and features: Proven method that emphasizespreliminaries toevery chapter Integrates the 'why' concepts of 3-D simultaneously with the 'how-to' techniques Skills reinforced with tutorials and chapter projects Real-world experience distilled into helpful hints and step-by-step guides for common tasksSpringer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 344 pp. Englisch.

  • Jiming Liu

    Sprache: Englisch

    Verlag: Springer US, Springer New York Dez 2004, 2004

    ISBN 10: 1402081219 ISBN 13: 9781402081217

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    Buch. Zustand: Neu. Neuware -Autonomy Oriented Computing is a comprehensive reference for scientists, engineers, and other professionals concerned with this promising development in computer science. It can also be used as a text in graduate/undergraduate programs in a broad range of computer-related disciplines, including Robotics and Automation, Amorphous Computing, Image Processing, Programming Paradigms, Computational Biology, etc.Part One describes the basic concepts and characteristics of an AOC system and enumerates the critical design and engineering issues faced in AOC system development. Part Two gives detailed analyses of methodologies and case studies to evaluate AOC used in problem solving and complex system modeling. The final chapter outlines possibilities for future research and development.Numerous illustrative examples, experimental case studies, and exercises at the end of each chapter of Autonomy Oriented Computing help particularize and consolidate the methodologies and theories presented.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 252 pp. Englisch.