Springer us sep 2012 (6 Ergebnisse)

Taschenbuch. Zustand: Neu. Neuware - With great pleasure I welcome you to the City of Groningen. In more than one way there is cause for celebration. Today marks the third lustrum of the annual international sympo sium on blood transfusion, organized by the Rode Kruis Bloedbank Groningen-Drenthe. In my opinion it has been a remarkable initiative of the Bloedbank, to start organizing a scientific conference, as it did, in 1976. It meant, among others, that in case of success the initiative would grow to be an annual item on the international congress calen der. It also meant that a possible third lustrum would coincide with the celebration of the 950th anniversary of the City of Groningen. I am happy to note that the initiative has been successful: over the past fourteen years the Rode Kruis Bloedbank Groningen-Drenthe has succeeded in organizing an annual symposium on blood transfusion, with a different theme each year, and with an average attendance of 250 participants from some 26 countries world-wide. The platform created with the special formula of the symposium, for science and industry, has been well balanced and beneficial to both. Mr. Chairman, ladies and gentlemen, I like to compliment the organizers with the success that they have attained. Allow me to men tion the name of just one person, in whom I like to thank everyone who has been involved in creating the annual Bloedbank-symposia: my warm congratulations to Dr. Smit Sibinga and his staff.…

Taschenbuch. Zustand: Neu. Neuware - Rapid advances in neural sciences and VLSI design technologies have provided an excellent means to boost the computational capability and efficiency of data and signal processing tasks by several orders of magnitude. With massively parallel processing capabilities, artificial neural networks can be used to solve many engineering and scientific problems. Due to the optimized data communication structure for artificial intelligence applications, a neurocomputer is considered as the most promising sixth-generation computing machine. Typical applica tions of artificial neural networks include associative memory, pattern classification, early vision processing, speech recognition, image data compression, and intelligent robot control. VLSI neural circuits play an important role in exploring and exploiting the rich properties of artificial neural networks by using pro grammable synapses and gain-adjustable neurons. Basic building blocks of the analog VLSI neural networks consist of operational amplifiers as electronic neurons and synthesized resistors as electronic synapses. The synapse weight information can be stored in the dynamically refreshed capacitors for medium-term storage or in the floating-gate of an EEPROM cell for long-term storage. The feedback path in the amplifier can continuously change the output neuron operation from the unity-gain configuration to a high-gain configuration. The adjustability of the vol tage gain in the output neurons allows the implementation of hardware annealing in analog VLSI neural chips to find optimal solutions very efficiently. Both supervised learning and unsupervised learning can be implemented by using the programmable neural chips.…

Taschenbuch. Zustand: Neu. Neuware - As MOS devices are scaled to meet increasingly demanding circuit specifications, process variations have a greater effect on the reliability of circuit performance. For this reason, statistical techniques are required to design integrated circuits with maximum yield. Statistical Modeling for Computer-Aided Design of MOS VLSI Circuits describes a statistical circuit simulation and optimization environment for VLSI circuit designers. The first step toward accomplishing statistical circuit design and optimization is the development of an accurate CAD tool capable of performing statistical simulation. This tool must be based on a statistical model which comprehends the effect of device and circuit characteristics, such as device size, bias, and circuit layout, which are under the control of the circuit designer on the variability of circuit performance. The distinctive feature of the CAD tool described in this book is its ability to accurately model and simulate the effect in both intra- and inter-die process variability on analog/digital circuits, accounting for the effects of the aforementioned device and circuit characteristics. Statistical Modeling for Computer-Aided Design of MOS VLSI Circuits serves as an excellent reference for those working in the field, and may be used as the text for an advanced course on the subject.…

Taschenbuch. Zustand: Neu. Neuware - This volume is intended to present an eclectic selection of informative reviews on aspects of the malignant lymphomas, including Hodgkin's disease. The choice of suitable review topics in this field is made hazardous by several facts. First, the growth of insight into basic mechanisms of lymphomagenesis is explosive, as is the expansion of our understanding of the need for precise morphologic classification of these diseases. Second, new therapeutic agents, cytotoxic and biologic, as well as new drug delivery strategies, are appearing with remarkable frequency. Finally, old 'standard' approaches, such as the staging laparotomy for Hodgkin's disease, are being reconsidered and deserve attention in an up-to-date collection of papers. The 10 reviews presented here fall generally into three categories. First, the optimal diagnostic and therapeutic approaches to Hodgkin's disease are considered by Mark Leibenhaut, who reviews the status of the diagnostic staging laparotomy, and by Philip Bierman, who discusses his thoughts on the timing of high-dose treatment with bone marrow transplantation for this disease. There follow four reviews of current management of specific histologic subtypes of malignant lymphoma. First, Velasquez reviews prognostic factors in both intermediate and high grade lymphomas. Miller and Dahlberg review and update the Southwest Oncology Group experience in developing curative cytotoxic combination therapies for diffuse large-cell lymphomas. Lastly, optimal therapy for two kinds of high grade lymphoma are presented. Butler and Hainsworth describe the Vanderbilt experience with diffuse small noncleaved cell lymphoma and Picozzi reviews lymphoblastic lymphoma.…

Taschenbuch. Zustand: Neu. Neuware - Digital BiCMOS Integrated Circuit Design is the first book devoted entirely to the analysis and design of digital BiCMOS integrated circuits. BiCMOS Integrated Circuit Design also reviews CMOS and CML integrated circuit design. The application of BiCMOS in the design of digital subsystems, e.g. adders, multipliers, RAMs and PLAs is addressed. The book also introduces the reader to IC process technology: CMOS, bipolar and BiCMOS. The modeling of both the bipolar and MOS devices are covered. Many process/device/circuit design issues are discussed. Digital BiCMOS Integrated Circuit Design can be used by engineers, researchers, graduate and senior undergraduate students working in the area of digital integrated circuits, digital circuits and system design, BiCMOS process and device modeling.…

Taschenbuch. Zustand: Neu. Neuware - In our environmentally conscious society, reports of an increase in the risk of developing several cancers - including melanoma, lymphoma and lung cancer - have excited great controversy. Of these tumors, melanoma has demonstrated the most spectacular increase, generating a considerable body of research. The justification for this volume is found in the need for an up-to-date review of this research. The book represents a comprehensive review of both current research and clinical management of melanoma, arranged in such a way as to be maximally user-friendly to both the basic scientst and the clinician interested in this fascinating disease. …