Springer us jul 2005 (12 Ergebnisse)

Buch. Zustand: Neu. Neuware - Nanotechnology has received tremendous interest over the last decade, not only from the scientific community but also from a business perspective and from the general public. Although nanotechnology is still at the largely unexplored frontier of science, it has the potential for extremely exciting technological innovations that will have an enormous impact on areas as diverse as information technology, medicine, energy supply and probably many others. The miniturization of devices and structures will impact the speed of devices and information storage capacity. More importantly, though, nanotechnology should lead to completely new functional devices as nanostructures have fundamentally different physical properties that are governed by quantum effects. When nanometer sized features are fabricated in materials that are currently used in electronic, magnetic, and optical applications, quantum behavior will lead to a set of unprecedented properties. The interactions of nanostructures with biological materials are largely unexplored. Future work in this direction should yield enabling technologies that allows the study and direct manipulation of biological processes at the (sub) cellular level.…

Buch. Zustand: Neu. Neuware - As the drug abuse epidemic evolves, so do the tools needed to understand and treat it. Accordingly, Epidemiology of Drug Abuse takes the long view, cogently outlining what the book calls 'the natural history of drug abuse' and redefining its complex phenomena to reflect our present-day knowledge. Twenty-six eminent contributors discuss the state and future of the field, balancing the practical concerns involved in gathering drug abuse data with the ethics of using the information.- Current thinking on pathways and etiology, as well as medical, psychological, and social sequelae of drug abuse- Proven, up-to-date methodologies for assessment- Challenges of gathering data from high-risk and other user populations- Sampling and application issues- Uses, sources, and limitations of treatment data- Analytical papers applying the methodologies to specific and global studies - The role of epidemiology studies in developing prevention strategiesWith this multifaceted approach to the subject, Epidemiology of Drug Abuse provides researchers and educators with a reference that sheds significant light on infrequently covered areas. In addition, its breadth and accessibility of coverage make it a teaching text suitable to courses in epidemiology, public health, and drug abuse.…

Buch. Zustand: Neu. Neuware - It is widely acknowledged that the cost of validation and testing comprises a s- nificant percentage of the overall development costs for electronic systems today, and is expected to escalate sharply in the future. Many studies have shown that up to 70% of the design development time and resources are spent on functional verification. Functional errors manifest themselves very early in the design flow, and unless they are detected up front, they can result in severe consequence- both financially and from a safety viewpoint. Indeed, several recent instances of high-profile functional errors (e. g. , the Pentium FDIV bug) have resulted in - creased attention paid to verifying the functional correctness of designs. Recent efforts have proposed augmenting the traditional RTL simulation-based validation methodology with formal techniques in an attempt to uncover hard-to-find c- ner cases, with the goal of trying to reach RTL functional verification closure. However, what is often not highlighted is the fact that in spite of the tremendous time and effort put into such efforts at the RTL and lower levels of abstraction, the complexity of contemporary embedded systems makes it difficult to guarantee functional correctness at the system level under all possible operational scenarios. The problem is exacerbated in current System-on-Chip (SOC) design meth- ologies that employ Intellectual Property (IP) blocks composed of processor cores, coprocessors, and memory subsystems. Functional verification becomes one of the major bottlenecks in the design of such systems.…

Buch. Zustand: Neu. Neuware - This book records one of the continuous attempts of the IFIP Working Group 8. 2, studying the interaction of information systems and the organization, to explore and understand the shifting boundaries and dependencies between organizational activities and their computer support. The book marks the result of the IFIP WG 8. 2 conference on 'Designing Ubiquitous Information Environments: Socio-Technical Issues and Challenges. ' Since its inception in the late 1970s, IFIP WG 8. 2 has sought to understand how computer-based information systems interact and must be designed as an integrated part of the organizational design. At that time, information systems handled repetitive and remote back-office functions and the main concern was work task design for repetitive input tasks and the potential impact of improved information support on organizational decision-making and structure. The focus of the information system design shifted in the 1980s when computers became part of the furniture and moved into the office. Reflecting this significant change, IFIP WG 8. 2 in 1989 organized a conference dedicated to the design and impact of desktop technology in order to examine how organizational processes and the locus of action changed when the computer was moved into the office. Sixteen years later, we are experiencing another significant change. Computers are now becoming part of our body and sensory system and will move out of the traditional office locations and into the wilderness. Again, IFIP WG 8.…

Buch. Zustand: Neu. Neuware - This unique book, drawing on the author's lifetime experience, critically evaluates the extensive literature on the field of Metal-Catalysed Reactions of Hydrocarbons. Emphasis is placed on reaction mechanisms involving hydrogenation, hydrogenolysis, skeletal and positional isomerisation, and exchange reactions. The motivation for fundamental research in heterogeneous catalysis is to identify the physicochemical characteristics of active centres for the reaction being studied, to learn how these may be modified or manipulated to improve the desired behavior of the catalyst, and to recognize and control those aspects of the catalyst's structure that limit its overall performance. By restricting the subject of the book to hydrocarbons, Bond has progressively developed the subject matter to include areas of importance both to researchers and to those working in the industry.…

Buch. Zustand: Neu. Neuware - Oxides form a broad subject area of research and technology development which encompasses different disciplines such as materials science, solid state chemistry, physics etc. The aim of this book is to demonstrate the interplay of these fields and to provide an introduction to the techniques and methodologies involving film growth, characterization and device processing. The literature in this field is thus fairly scattered in different research journals covering one or the other aspect of the specific activity. This situation calls for a book that will consolidate this information and thus enable a beginner as well as an expert to get an overall perspective of the field, its foundations, and its projected progress.…

Buch. Zustand: Neu. Neuware - Knowledge Management and Data Mining in Biomedicine covers the basic foundations of the area while extending the foundational material to include the recent leading-edge research in the field. The newer concepts, techniques, and practices of biomedical knowledge management and data mining are introduced and examined in detail. It is the research and applications in these areas that are raising the technical horizons and expanding the utility of informatics to an increasing number of biomedical professionals and researchers. These concepts and techniques are illustrated with detailed case studies.…

Buch. Zustand: Neu. Neuware - This book brings together authors with expertise in a wide range of fields to provide an up to the minute overview of the most important problems relating to mercury in the environment. The book reflects growing concern over the likelihood of harmful effects to human health and sensitive ecosystems posed by mercury in the light of increasing fossil fuel combustion, mercury use in a range of manufactured goods, and the lack of emission control policies. Concern has been expressed at local, national, and international levels; in the last three years both the European Commission and UNEP have published reports on mercury in the environment. Growing concern has led to an increased effort to understand the fate of mercury in the environment, including primary production and trade in mercury, emissions from manufacturing and power generation, natural emissions and re-emission, atmospheric transport and transformation, deposition patterns, uptake by biota, and eventual health impacts on living organisms. The increasing specialisation, and amount of research in the numerous scientific fields associated with the study of the fate of mercury in the environment, make the publication of this book both necessary and timely. For experts, and non-experts, who require both the broader picture, as well as an awareness of the latest progress in the fields relevant to mercury research, this book provides the most comprehensive and up to date overview available. The book has five sections.…

Buch. Zustand: Neu. Neuware - An increasing number of system designers are using ASIP s rather than ASIC s to implement their system solutions. Building ASIPs: The Mescal Methodology gives a simple but comprehensive methodology for the design of these application-specific instruction processors (ASIPs).The key elements of this methodology are:Judiciously using benchmarkingInclusively identifying the architectural spaceEfficiently describing and evaluating the ASIPsComprehensively exploring the design spaceSuccessfully deploying the ASIPThis book includes demonstrations of applications of the methodologies using the Tipi research framework as well as state-of-the-art commercial toolsets from CoWare and Tensilica.…

Buch. Zustand: Neu. Neuware - Epithelial phenotype is a dynamic stage of differentiation that can be modulated during several physiological or pathological events. The rapid conversion to a mesenchymal-like phenotype is called an epithelial-mesenchymal transition (EMT). The Rise and Fall of Epithelial Phenotype is the first book to comprehensively introduce the concept of EMT. The first part of this volume describes main examples and models and explains their physiological relevance. These examples include hydra morphogenesis, gastrulation in mouse, drosophila and sea urchin, as well as neural crest cell migration and heart morphogenesis in vertebrates. Part two reviews in detail, specific EMT molecular pathways covering extracellular induction, transduction and transcription response and modulation of cell-cell adhesion structures. It emphasizes new specific pathways with potential medical applications. EMTs can also be linked to pathological events such as wound healing and cancer progression, as detailed in this section of the book.…

Buch. Zustand: Neu. Neuware - This volume is comprised of the proceedings of the 13th International Conference on Information Systems Development held August 26th-28th, 2004, at Vilnius Gediminas Technical University, Vilnius, Lithuania. The aim of this volume is to provide a forum for the research and practices addressing current issues associated with Information Systems Development (ISD). Every day, new technologies, applications, and methods raise the standards for the quality of systems expected by organizations as well as end users. All are becoming dependent on systems reliability, scalability, and performance. Thus, it is crucial to exchange ideas and experiences, and to stimulate exploration of new solutions. This proceedings provides a forum for both technical and organizational issues.…

Buch. Zustand: Neu. Neuware - Hot Topics in Infection and Immunity II provides a current view from leading experts concerning the hottest topics of concern to clinicians caring for children with infections. The book brings together a collection of manuscripts from a faculty of authors of international standing who contributed to a course in Paediatric Infection and Immunity in Oxford, UK in June 2004.…