Springer us dez 2013 (9 Ergebnisse)
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Taschenbuch. Zustand: Neu. Neuware - Inverse and crack identification problems are of paramount importance for health monitoring and quality control purposes arising in critical applications in civil, aeronautical, nuclear, and general mechanical engineering. Mathematical modeling and the numerical study of these problems requir…e high competence in computational mechanics and applied optimization. This is the first monograph which provides the reader with all the necessary information. Delicate computational mechanics modeling, including nonsmooth unilateral contact effects, is done using boundary element techniques, which have a certain advantage for the construction of parametrized mechanical models. Both elastostatic and harmonic or transient dynamic problems are considered. The inverse problems are formulated as output error minimization problems and they are theoretically studied as a bilevel optimization problem, also known as a mathematical problem with equilibrium constraints. Beyond classical numerical optimization, soft computing tools (neural networks and genetic algorithms) and filter algorithms are used for the numerical solution. The book provides all the required material for the mathematical and numerical modeling of crack identification testing procedures in statics and dynamics and includes several thoroughly discussed applications, for example, the impact-echo nondestructive evaluation technique. Audience: The book will be of interest to structural and mechanical engineers involved in nondestructive testing and quality control projects as well as to research engineers and applied mathematicians who study and solve related inverse problems. People working on applied optimization and soft computing will find interesting problems to apply to their methods and all necessary material to continue research in this field.
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Taschenbuch. Zustand: Neu. Neuware - We are pleased to be able to honor Arthur J. Bronstein with this volume of essays. We are all the more pleased because the volume has consider able intrinsic merit, but neither the reader nor Arthur should have any doubts about our primary purpose in assembling this book. That the col lection… is intrinsically valuable is, in itself, a tribute to the man whom it honors: The contributing authors are all colleagues, students, and friends of Arthur. Readers who are acquainted with Arthur will not be surprised by the broad range of academic expertise which has been brought to bear on the subject of language in this book. They will recognize that Arthur's own range of expertise and interest is only barely matched by the contents of the essays and the backgrounds of their authors. On the other hand, those who know little about Arthur may have thought of him primarily in narrow association with phonetics and lin guistics, most likely as the author of The Pronunciation of American English, surely the most influential of American phonetics texts during the last quarter of a century. Although such an association is in many respects appropriate, it is altogether too limited, but this will not deter us from using it as the basis for a relevant and, we hope, revealing metaphor about Arthur J.
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Taschenbuch. Zustand: Neu. Neuware - Demontrating that the scope of clinincal psychology is much broader than had been previously thought, this new volume illustrates recent achievements in the field and outlines perspectives for futher applications in research and treatment.
Sprache: Englisch
Verlag: Springer Us Dez 2013 2013
Serie: Current Issues in Autism, Buch 8 von 8. Buch 8 von 8 - Current Issues in Autism
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Taschenbuch. Zustand: Neu. Neuware - As a division of the School of Medicine at the University of North Carolina at ChapeI Hili, TEACCH has always been involved in the latest biological research on autism and related developmental disabilities. However, until now there has not been sufficient information to justify aseparate vol…ume on this most important topic. Recent advances both in our under standing of the brain and in the technology to facilitate the measurement of neurological functioning have stimulated significant growth, which is reflected in this volume. As with the preceding books in this series, Current Issues in Autism, this volume is based on one of the annual TEACCH conferences held in ChapeI Hili each May. The books are not simply published proceedings of the conference papers, however. lnstead, conference participants are asked to develop chapters around their presentations, and other international experts whose work is beyond the scope of the conference, but related to the major theme, are asked to contribute as weil. These volumes are intended to provide the most current knowledge and professional practice available to us concerning major issues in autism.
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Taschenbuch. Zustand: Neu. Neuware - Six years ago when the first edition of this volume appeared as the first of the series, questions were posed in its preface that are as valid today as they were then. In that preface, I proposed the following challenges: (1) We must identify carcinogenic agents, and by an analysis of their '…nature,' e. g. , structure and physical characteristics, we may better understand their mechanism of action. (2) We must identify crucial interactions between these carcinogens and impor tant macromolecules within the cell, distinguishing those which relate to carcinogenesis from those which are extraneous. (3) We must examine the alterations of cell function induced by these reactions, for it is with an understanding of phenotypic variation that we may know why malignant cells escape from normal homeostatic control. (4) Last, and perhaps of greatest importance, we must define malignancy--define those charac teristics of cellular activity that permit the malignant cell to compete so effectively with the normal constituent, which ultimately Ieads to such destructive events. Although great strides have been made toward those goals, as evidenced by a number of new chapters and the new information gathered into others, and although the achievement of those goals sometimes appears but a tantalizing experiment away, none have been achieved. For example, several chapters indude descriptions of the progress that has been made toward the development of 'quick assays.
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Taschenbuch. Zustand: Neu. Neuware - This volume contains contributions that are interdisciplinary and inter national. The editors believe this is an especially timely and promising enterprise, for both sources of diversity are needed for improving our abilities to identify the young child at risk and to prevent disability. In t…erms of diSciplines, the volume brings together papers by health care providers (such as pediatricians and public health nurses) as well as educators and psychologists. Each of these groups works in dissimilar settings and faces dissimilar problems: Health care providers seek sim ple identification procedures for use in busy primary care settings; psy chologists emphasize well-constructed research designs; and educators reflect the need for early identification and education. Each of these spe cialist groups has something to offer the other, but too often each tends to limit its publications and readings to its own discipline, thus failing to capitalize on a wider scope. of knowledge and practice. We hope that this selection of papers will allow all readers addressing the early iden tification of children at risk to generate a more integrated interdiscipli nary perspective. We also hope this volume reflects the sense of excitement that we feel from a sharing of international perspectives. There is no single ap proach to the early identification of children at risk that is universally applicable to all countries. In addition, approaches within each country vary because of availability of financial and human resources and dif fering expectations of local communities.
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Taschenbuch. Zustand: Neu. Neuware - Atomic transport in solids is a field of growing importance in solid state physics and chemistry, and one which, moreover, has important implications in several areas of materials science. This growth is due first to an increase in the understanding of the fund amentals of transport processes… in solids. Of equal importance, however, have been the improvements in the last decade in the experi mental techniques available for the investigation of transport phenomena. The advances in technique have stimulated studies of a wider range of materials; and expansion of the field has been strong ly encouraged by the increasing range of applied areas where transport processes play an essential role. For example, mass transport phenomena play a critical role in the technology of fabrication of components in the electronics industry. Transport processes are involved both during the fabrication and operation of devices and with the growing trend to miniaturisation there are increasing demands on accurate control of diffusion processes. The present book (which is based on a NATO sponsored Advanced Study Institute held in 1981 at Lannion, France) aims to present a general survey of the subject, highlighting those areas where work has been especially active in recent years.
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Taschenbuch. Zustand: Neu. Neuware - Proceedings of a NATO ASI held in Les Arcs, France, April 2--13, 1990.
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Taschenbuch. Zustand: Neu. Neuware - V Pentostam, an uncharacterized complex of Sb and carbohydrate derived from gluconic acid, is concentrated by Leishmania amastigotes via protein binding. Biochemical consequences of the interaction of amastigotes with Pentostam are inhibition of parasite bioenergetics and inhibition of ATP sy…nthesis. REFERENCES 1. J.C. Mottram and G.H. Coombs. Enzyme activities of amastigotes and promastigotes and their inhibition by antimonials and arsenicqls. Exper. Parasitol. 59:151 (1985). 125 2. S.L. Croft, K.D. Neame and C.A. Homewood. Accumulation of [ Sb] sodium stibogluconate by Leishmania mexicana amazonensis and Leishmania donovani in vitro. Compo Biochem. Physiol. 68c:95 (1981). 3. J.D. Berman, J.V. Gallalee, and B.D. Hansen. Leishmania mexicana: uptake of sodium stibogluconate (Pentostam) and pentamidine by parasite and macrophages. Exper. Parasitol. 64:127 (1987). 4. J.D. Berman, D. Waddell and B.D. Hanson. Biochemical meChanisms of the antileishmanial activity of sodium stibogluconate. Antimicrobial Agents Chemotherapy. 27:916 (1985). 5. J.D. Berman, J.V. Gallalee, and J.M. Best. Sodium stibogluconate (Pentostam) inhibition of glucose catabolism via the glycolytic pathway, and fatty acid B-oxidation in Leishmania mexicana amastigotes. Biochem. Pharmacol. 36:197 (1987). 6. D.T. Hart and G.H. Coombs. Leishmania mexicana: Energy metabolism of amastigotes and promastigotes. Exper. Parasitol. 54:397 (1982). 478 EFFECTS OF SINEFUNGIN ON CELLULAR AND BIOCHEMICAL EVENTS IN PROMASTIGOTES OF LEISHMANIA d. donovani Fran~oise Lawrence, and MaIka Robert-Cero Institut de Chimie des Substances Naturelles C.N.R.S.
