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Taschenbuch. Zustand: Neu. Neuware -This volume of essays grew out of a symposium organized by Judith Hoch-Smith and Anita Spring for the 1974 American Anthropological Association meetings in Mexico City. The two-part symposium was enti tled 'Women in Ritual and Symbolic Systems: I. Midwives, Madonnas, and Mediums; ll. Prostitutes, Witches, and Androgynes. ' The sym posium participants were asked to explore theological, ritual, and sym bolic aspects-both positive and negative-of the feminine cultural do main, using ethnographic materials with which they were familiar. The resulting papers have been revised, edited, and gathered together in Women in Ritual and Symbolic Roles. The theoretical importance of these papers for the study of women's participation in culture and society rests on the assumption that reli gious ideas are paramount forces in social life, that relationships be tween the sexes, the nature of female sexuality, and the social and cul tural roles of women are in large part defined by religious ideas. That this proposition remains valid long after religion itself has ceased to be a living truth in the lives of many people can be seen from the tenacious ness of Judeo-Christian ideas about women in the contemporary West ern world. Both the expansion of life options for women and the creation of more positive cultural images of the female are intimately related to changes in the my tho-symbolic portraits that people carry around in their heads. These portraits are almost exclusively constructed from mythological and religious conceptions inherent in all facets of culture.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 308 pp. Englisch. …

Taschenbuch. Zustand: Neu. Neuware - 1 The Chondrodystrophies.- Classification of the Chondrodystrophies.- Evaluation of the Dwarfed Patient.- Clinical, Radiographic, Genetic, and Pathological Features of the Chondrodystrophies.- Animal Models of the Chondrodystrophies.- Future Trends in Chondrodystrophy Research.- 2 New Techniques in the Study of Human Chromosomes: Methods and Applications.- Fluorescence Microscopy.- Giemsa Staining.- The Usage of Banding Techniques.- Abnormalities Detected by Banding Analysis.- Chemical Properties of the Bands.- Technical Appendix.- 3 The Thalassemias: Models for Analysis of Quantitative Gene Control.- History.- Definition.- Organization of Globin Genes.- Ontogeny of Hemoglobin Production.- Inheritance of Thalassemia.- Frequency of Thalassemia.- Regulation of Hemoglobin Synthesis and Turnover.- Transcription of Hemoglobin Genes.- Intranuclear Processing of the Primary Gene Product.- Transport of Messenger RNA to the Cytoplasm.- Cytoplasmic Metabolism of Messenger RNA.- Balance of Hemin and Globin (Protein) Synthesis in Reticulocytes.- Other Steps in Hemoglobin Synthesis and Degradation.- Pathophysiology of the Thalassemias.- Directions in Therapy.- Note Added in Proof.- 4 Spontaneous Mutation in Man.- 'Classical' Mutation Rates.- Molecular Aspects of Human Mutation.- Spontaneous Mutation in Other Organisms and Its Significance for the Understanding of Human Mutations.- 5 Genetic Screening Legislation.- The Public Health Power.- Legislation Mandating Detection of Genetic Disease.- Legislation Mandating Screening for Genetic Traits.- Future of State-Supported Genetic Screening.…

Taschenbuch. Zustand: Neu. Neuware - Volume 9 of Developments in Applied Spectroscopy pr e sents a collection of tventy-three selected papers presented during the 21st Mid-America Symposium on Spectroscopy, held in Chicago, June 2-5, 1970, In general. these papers are those of the symposium type and not papers pertaining to a specific research topic that one voul~ expect to find in the journals. The 21st Mid-America Symposium vas sponsored by the Chicago Section in cooperation vith Cincinnati, Cleveland, Indiana, Nev England, Nev York, Niagara Frontier and Ohio Vall ey Sections of the Society of Applied Spectroscopy, and the Chicago Gas Chromatography Group. Although the Mid America is stiIl occasionally thought of as a regional meet ing, its attendees and authors come from all parts of the United States and Canada as vell as other countries outside North America. Both theoretieal and applied principles vere presented in sessions on emission, molecular and atomic absorption, x-ray, mass, nuclear, electron, and nuclear magnetic and electron spin resonanee spectroscopy; air and Water pOllution analyses; biomedical technology; polymers and elastomeric materials; and computer applications. The chairmen of the Symposium Committees, Mr. E. Baclavski. Dr. W. K. Baer, Mr. J. E. Burroughs, Dr. C. R. Brundle, Mr. C. Hastings, Mr. J. B. Himes, Mr. R. Isaac, Dr. R. J. Jakobsen, Mr. J. Kinder, Dr. J. L. Koenig, Mr. W. A. Loseke, Dr. R. Mattoon, Miss V. McMahon, Dr. C.E. Moore, Mr. C. S. Naiman, Dr. M. J. Oestmann, Mr. C. R.…

Taschenbuch. Zustand: Neu. Neuware - Advances in Microbial Ecology was established by the International Commis sion on Microbial Ecology to provide a vehicle for in-depth, critical, and, it is hoped, provocative reviews on aspects of both applied and basic microbial ecol ogy. In the five years of its existence, Advances has achieved recognition as a major source of information and inspiration both for practicing and f.…

Taschenbuch. Zustand: Neu. Neuware - Each of the four authors of this book has a particular interest in disorders of porphyrin metabolism and special experience in their management. Their individual involvement in the field varies from 12 to 52 years and, combined, represents more than a century of personal experience. Since it has been written by both basic scientists and practicing physicians, the book is intended to be of value to all those involved in porphyrin metab olism and the porphyrias. It is hoped that the fascination of porphyrin metabolism and the clinical challenge of the porphyrias experienced by each of the authors will be conveyed to the readers. Michael R. Moore Kenneth E. L. McColl Claude Rimington Abraham Goldberg vii CONTENTS Color Plates . xvii 1. The History, Classification, and Incidence of the Porphyrias 1 1.1. History . 1 1.1.1. Early Chemistry . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 1.1.2. Early Descriptions of Porphyria . 4 1.1.3. Biochemical Developments . 4 1.1.4. Acute Porphyria . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 1.1.5. A Complete Pathway . 8 1.2. Classification of the Porphyrias . . . . . . . . . . . . . . . . . . . . . 9 1.2.1. The Current Classification. . . . . . . . . . . . . . . 12 . . . .…

Taschenbuch. Zustand: Neu. Neuware - Sociobiology is the play of the season. Its success is mellsured by its immense popularity and perhaps by the controversy it has generated as well. Unfortunately, neither its popularity nor the resulting controversy seems likely to assure progress toward understanding sociobiological issues. The play has too many actors and, it seems, the casting has been poor; the players are unable to maintain their roles. At center stage, of course, is E. O. Wilson and his monumental opus Sociobiology. 1 In the wings, and making periodic entrances, are an assort ment of brilliant, committed, and aggressive adversaries. On cue, one of them steps out and decries the self-fulfilling nature of sociobiological prophesies. The arguments of the adversaries are varied. They warn that if all nonhuman primate societies tolerate aggression and man is also a pri mate, then aggression may come to be considered 'normal' and therefore acceptable. Their dire warnings may also have real impact on policy, alter ing, for example, a research program intended to examine longitudinally the relation between a supernumerary chromosome and certain behavioral disorders. The rationale is that since the afflicted infants would have to be identified and the study obviously does assume that psychopathology is linked to the chromosome aberration, the attitudes of the child's parents could well contribute to abnormal behavior that might otherwise not appear.…

Taschenbuch. Zustand: Neu. Neuware - This book includes the proceedings of a NATO Advanced Study Institute held at Washington State University, Pullman, Washington from July 26 until August 6, 1982. Although genetic engineering in eukaryotes is best developed in yeast and mammalian cells, the reader will find that some emphasis has been put on plant systems. Indeed, it was our position that the development of plant cell genetic transformation would benefit from the interactions between a comparatively smaller number of fungal and animal cell experts and a larger number of plant cell specialists representing various aspects of plant molecular genetic research. On the other hand, it is clear that the ultimate achievements of plant genetic engineering will have a tremendous ~pact on, among other things, food production without generating the problems of ethics encountered when one contempla-tes the genetic modification of human beings. Therefore, this slight bias in favor of the plant kingdom simply reflects our belief that a 'second green revolution' will benefit mankind to a greater extent than any other kind of genetic engine ering. The keynote lecture of the Institute was delivered by Dr. John Slaughter, Director of the National Science Foundation, whom we deeply thank for his words of encouragement and commitment to the genetic manipulation of plants.…

Taschenbuch. Zustand: Neu. Neuware.

Taschenbuch. Zustand: Neu. Neuware - Volume 4 of Advances in Nutritional Research reflects the increased importance that recently has been attached to nutrition in many fields of clinical medicine. This heightened interest in nutrition stems from the demonstration that the intake of specific nutrients may have far-reaching consequences, not only for normal metabolism, but also for metabolic processes affecting clinical or subclinical disease. Conversely, many disease states have been shown to have previously unrecognized effects on nutrient function and metabolism. In addition to topics of obvious relevance to human clinical nutrition, this volume contains chapters dealing with the nutrition of cells grown in culture and of species that may provide insights into nutritional disorders of man. To gether with its predecessors, Volume 4 provides graduate students and estab lished investigators with authoritative accounts of the status of research on a range of topics of current interest in experimental and clinical nutrition. vii Contents Chapter 1. Vitamin-Responsive Genetic Abnormalities . . S. Harvey Mudd 1. Introduction. 1 2. Historical Perspective . 2 3. Genetic Abnormalities Currently Known to Be Vitamin Responsive. 3 4. Mechanisms Underlying Vitamin Responsiveness. . . . . . . . . . . . . . . . 7 4.1. Defects in the Processing of a Vitamin Prior to Its Interaction in Cofactor Form with a Particular Apoenzyme . 7 4.2. Defects in Particular Apoenzymes that Interact with the Cofactor Forms of Vitamins. . . . . . . . . . . . . . . . . . 16 . . . . . .…

Taschenbuch. Zustand: Neu. Neuware - Transposon tagging can work. Even though most of our understand ing about the factors that contribute to a successful tagging experiment has been accumulated from a limited number of experiments using different transposable elements in different genetic backgrounds, it is still possible to draw some conclusions regarding the best experimental strategies for gene tagging. In our experience, Spm has proved to be a good element for transposon tagging. The frequency of recovering mutable alleles in duced by Spm is not significantly different from that for Ac-Ds or for Mu 6 (summarized in Ref. 22) and varies from about 10- to 10=zr:-8pm has the unique advantage, however, in that all of the members of thiSfumily that have been examined thus far are homologous to each other at the DNA level. Therefore, by combining molecular analysis with genetic segre gation, it is possible to identify and isolate alleles that are due to insertions of either autonomous or nonautonomous Spm elements. There are definite steps one can take to increase the chances of de tecting a transposition into the gene of interest. The most important step is to select a genetic background in which the desired phenotype will be easy to screen. If the phenotype is not likely to be mutable, then tester lines should be constructed so as to contain flanking markers that can aid in subsequent segregation analyses.…

Taschenbuch. Zustand: Neu. Neuware - A satellite symposium entitled 'Myelination and Demyelination: Recent Chemical Advances' was held in Helsinki from August 29 to 31, 1977, after the Sixth International Meeting of the International Society for Neurochemistry (ISN) in Copenhagen. Myelin is a nervous tissue structure that is most suitable as a subject of biochemical investigation. It is easy to isolate in a highly purified form, is rather stable even after death, and is af fected by a variety of neurological and other diseases. Its lesions are particularly important in the study of multiple sclerosis, a disease which is relatively prevalent in Finland and has therefore been of interest to a great many Finnish scientists. The first half of this book is concerned with the biochemical composition and molecular organization of myelin, the second half with the experimental and clinical aspects of demyelination. The comments given after each of the presentations at the symposium were not recorded as such, but each author was requested to modify his or her paper accordingly. The editing and publication of this book would not have been possible without the excellent efforts and co-operation of my wife, Mrs. L.-M. Palo, acting as general secretary and later as editorial secretary of the symposium. As Organizing Committee Chairman, I would also like to thank the members of the Committee: Dr. M. Haltia, Dr. E. Kivalo, Dr. T. Kosunen, Dr. M. Panelius, and especially Dr.…

Taschenbuch. Zustand: Neu. Neuware - Since 1966, at ro~ghly three-yearly intervals, an internation al group of immunologists has met somewhere in Europe to discuss the latest developments in our understanding of the mechanisms governing the functioning of the immune system in vivo. These meetings have become known as the International C,mferences on Lymphatic Tissues and Germinal Centers in Immune Reactions, or for the regular devotees, simply as the Germinal Cent'~r Conferences (GCC). This volume represents the proceedings of the 8th GCC, which was held in Babraham, near Cambridge, UK, between the 14th and 17th August, 1984. When one considers how cellular immunology has become increas ingly dominated by in vitro methodology over the past twenty years, it may seem remarkable that these conferences hav~ survived at all, let alone prospered. However, I for one do not find this surprising, since I suspect that the exquisitely :omplex architect ure and microenvironments of the lymphoid system will never be fully understood through in vitro studies. If 'tae proper study of mankind is ~an', then surely ultimately the proper study of all the interacting elements which comprise the immune system has to be in vivo. This belief is shared by a substantial number of immunol ogists, as the contents of this volume will attest. Although the GCC were originally devoted to unravelling the mysteries of the germinal center response (and these are still not fully resolved), over the years the scope of the meetings has inevitably broadened.…

Taschenbuch. Zustand: Neu. Neuware - Neural Network Parallel Computing is the first book available to the professional market on neural network computing for optimization problems. This introductory book is not only for the novice reader, but for experts in a variety of areas including parallel computing, neural network computing, computer science, communications, graph theory, computer aided design for VLSI circuits, molecular biology, management science, and operations research. The goal of the book is to facilitate an understanding as to the uses of neural network models in real-world applications. Neural Network Parallel Computing presents a major breakthrough in science and a variety of engineering fields. The computational power of neural network computing is demonstrated by solving numerous problems such as N-queen, crossbar switch scheduling, four-coloring and k-colorability, graph planarization and channel routing, RNA secondary structure prediction, knight's tour, spare allocation, sorting and searching, and tiling. Neural Network Parallel Computing is an excellent reference for researchers in all areas covered by the book. Furthermore, the text may be used in a senior or graduate level course on the topic.…