springer springer jun 2005 (54 Ergebnisse)

Buch. Zustand: Neu. Neuware - Many current texts in the area are just cookbooks and, as a result, students do not know why they perform the methods they are taught, or why the methods work. The strength of this book is that it readdresses these shortcomings; by using examples, often from real life and using real data, the authors show how the fundamentals of probabilistic and statistical theories arise intuitively.A Modern Introduction to Probability and Statistics has numerous quick exercises to give direct feedback to students. In addition there are over 350 exercises, half of which have answers, of which half have full solutions. A website gives access to the data files used in the text, and, for instructors, the remaining solutions. The only pre-requisite is a first course in calculus; the text covers standard statistics and probability material, and develops beyond traditional parametric models to the Poisson process, and on to modern methods such as the bootstrap.

Taschenbuch. Zustand: Neu. Neuware - Testing is the primary hardware and software verification technique used by industry today. Usually, it is ad hoc, error prone, and very expensive. In recent years, however, many attempts have been made to develop more sophisticated formal testing methods. This coherent book provides an in-depth assessment of this emerging field, focusing on formal testing of reactive systems.This book is based on a seminar held in Dagstuhl Castle, Germany, in January 2004. It presents 19 carefully reviewed and revised lectures given at the seminar in a well-balanced way ensuring competent complementary coverage of all relevant aspects. An appendix provides a glossary for model-based testing and basics on finite state machines and on labelled transition systems. The lectures are presented in topical sections on testing of finite state machines, testing of labelled transition systems, model-based test case generation, tools and case studies, standardized test notation and execution architectures, and beyond testing.

Taschenbuch. Zustand: Neu. Neuware - MARSWALK ONE: First Steps on a New Planet addresses the question of why we should embark on a journey to Mars, documenting what the first human crew will do when they place their feet in the red dust of the planet. The book also addresses why we need to carry out these tasks and, more importantly, what a human crew could achieve that an automated mission could not. Understanding the clear benefits of sending a human crew to the surface of Mars, and how these benefits can be seen back on Earth, is the key to sustained long-term public and political support for the programme in terms of cash and commitment.The book accepts that the journey will be made, but does not specify precisely when. Flight time, and how to get to and from the planet are discussed briefly, to understand why the suggested duration spent at Mars is reasonable.The main objective of the work is to look at what science will be done on the surface - supported by orbital operations - and what hardware and technology will be employed to achieve the mission objectives. This analysis is drawn from previous experiences in manned and unmanned space programmes, including Apollo, Skylab, Salyut/Mir, Shuttle and ISS, Viking, Luna/Lunokhod, and recent Mars missions such as Pathfinder and Global Surveyor.In addition, new interviews with key personalities involved in planning Martian exploration, and discussions about current thoughts on what we need to accomplish on Mars when we get there, will provide a lively and thought provoking account that could generate fresh debate.When the decision is finally made to go to Mars, it will be made in the knowledge that most of the world knows why we are going and what benefits mankind will see for the effort. The authors' primary objective is to begin this understanding.

Taschenbuch. Zustand: Neu. Neuware - Entrepreneurship is a phenomenon of tremendous societal importance. It is also an elusive phenomenon, and researching entrepreneurship is therefore fun, fascinating and frustrating at times. In Researching Entrepreneurship, Per Davidsson, one of the most highly recognized entrepreneurship scholars shares in a personal and readable way his rich experience and ideas on how entrepreneurship can or should be researched. After a comprehensive treatment of entrepreneurship as societal phenomenon and scholarly domain, the core chapters of the book discuss design, sampling, operationalization and analysis issues on several levels of analysis: individual, venture, firm, industry, region and nation. The book is targeted at doctoral students and other relative newcomers to the field of entrepreneurship research. However, taking a fresh, reflective perspective and looking beyond research conventions, it should provide potential for inspiration and food for thought also for experienced entrepreneurship researchers.

Buch. Zustand: Neu. Neuware - A symptom-based version of the critically-acclaimed Norton/Surgery: Basic Science and Clinical Evidence, Learning Surgery provides a ready reference to those in third and fourth year residencies. Essential algorithms and case presentations meet with clerkship learning objectives as outlined by the Association of Surgical Education in their ASE Manual. Two sections include Introduction to Clinical Surgery in the Surgical Clerkship Setting and Management of Surgical Diseases During the Clerkship. Chapters include: Stroke, Hypertension, Abdominal Masses, Head Injuries, and Burns. Written by leading clinicians and educators, both surgery residents and medical students will find LEARNING SURGERY indispensible in their rotations and clerkships. Surgeons who train residents will also find the text a valuable ajunct to their teaching.

Taschenbuch. Zustand: Neu. Neuware - Combinatorial commutative algebra is an active area of research with thriving connections to other fields of pure and applied mathematics. This book provides a self-contained introduction to the subject, with an emphasis on combinatorial techniques for multigraded polynomial rings, semigroup algebras, and determinantal rings. The eighteen chapters cover a broad spectrum of topics, ranging from homological invariants of monomial ideals and their polyhedral resolutions, to hands-on tools for studying algebraic varieties with group actions, such as toric varieties, flag varieties, quiver loci, and Hilbert schemes. Over 100 figures, 250 exercises, and pointers to the literature make this book appealing to both graduate students and researchers.

Buch. Zustand: Neu. Neuware - Perturbation theory, one of the most intriguing and essential topics in mathematics, and its applications to the natural and engineering sciences is the main focus of this workbook. In a systematic introductory manner, this unique book deliniates boundary layer theory for ordinary and partial differential equations, multi-timescale phenomena for nonlinear oscillations, diffusion and nonlinear wave equations. The book provides analysis of simple examples in the context of the general theory, as well as a final discussion of the more advanced problems. Precise estimates and excursions into the theoretical background makes this workbook valuable to both the applied sciences and mathematics fields. As a bonus in its last chapter the book includes a collection of rare and useful pieces of literature, such as the summary of the Perturbation theory of Matrices.Detailed illustrations, stimulating examples and exercises as well as a clear explanation of the underlying theory makes this workbook ideal for senior undergraduate and beginning graduate students in applied mathematics as well as science and engineering fields.

Taschenbuch. Zustand: Neu. Neuware - Receding Horizon Control (RHC) introduces the essentials of a successful feedback strategy that has emerged in many industrial fields. RHC has several advantages over other types of control: greater adaptability to parametric changes than infinite horizon control; better tracking than PID and good constraint handling among others.The text builds understanding starting with optimal controls for simple linear systems and working through constrained systems to nonlinear cases. RHC is applied to discrete-time systems for easier computer application and its techniques are unified using the state-space framework. Examples and exercises allow you to practise as you go with MATLAB files for the solution of selected examples.Students following masters and doctoral courses in control will find this book an excellent companion to tuition and research. Tutors and academics researching predictive control can use it not only as a scholarly textbook but as a co-ordinated reference for its wide range of RHC schemes.

Taschenbuch. Zustand: Neu. Neuware -This book evolved from the first ten years of the Carnegie Mellon professional Master's program in Computational Finance. The contents of the book have been used successfully with students whose mathematics background consists of calculus and calculus-based probability. The author does not assume familiarity with advanced mathematical concepts from measure-theoretic probability, but rather develops the necessary tools from this subject informally within the text. Many classroom-tested examples, exercises, and intuitive arguments are presented throughout the book. 208 pp. Englisch.

Buch. Zustand: Neu. Neuware - Variational arguments are classical techniques whose use can be traced back to the early development of the calculus of variations and further. Rooted in the physical principle of least action they have wide applications in diverse fields. This book provides a concise account of the essential tools of infinite-dimensional first-order variational analysis. These tools are illustrated by applications in many different parts of analysis, optimization and approximation, dynamical systems, mathematical economics and elsewhere.Much of the material in the book grows out of talks and short lecture series given by the authors in the past several years. Thus, chapters in this book can easily be arranged to form material for a graduate level topics course. A sizeable collection of suitable exercises is provided for this purpose. In addition, this book is also a useful reference for researchers who use variational techniques---or just think they might like to.

Taschenbuch. Zustand: Neu. Neuware - Tutors can design entry-level courses in robotics with a strong orientation to the fundamental discipline of manipulator controlpdf solutions manualOverheads will save a great deal of time with class preparation and will give students a low-effort basis for more detailed class notesCourses for senior undergraduates can be designed around Parts I III; these can be augmented for masters courses using Part IV.

Buch. Zustand: Neu. Neuware - This book brings together for the first time the Kenneth May Lectures that were given at the annual meetings of the Canadian Society for History and Philosophy of Mathematics. All contributions are of high scholarly value, yet accessible to an audience with a wide range of interests. They provide a historian's perspective on mathematical developments and deal with a variety of topics covering Greek applied mathematics, the mathematics and science of Leonhard Euler, mathematical modeling and phenomena in ancient astronomy, Turing and the origins of artificial intelligence to name only a few.

Buch. Zustand: Neu. Neuware - Environmental impact assessments are required for a wide-range of projects throughout the world. These assessments have increasing involved complex, political decision-making and incorporated values and beliefs of both stakeholders and interested parties. However, the results are often ineffective because values and beliefs are not easily quantifiable, and decisions are considered subjective. This analysis recognizes these problems and proposes practical methods based on fuzzy logic that will enable people preparing assessments to define terms and quantify opinions and input so that they are agreed upon by all involved parties. Fuzzy logic also quantifies the complex environmental, economic and social conditions that are present and are predicted by project alternatives. The author places special emphasis on the types of issues that frequently arise in NEPA environmental assessments and environmental impact statements and in similar regulations that are used in jurisdictions regionally and internationally. The new methods are intended to reduce the time and cost of assessments, while producing justifiable results.First, issues related to current environmental impact assessment methods are discussed. Then the book discusses how lessons learned from computational intelligence can address these problems. It describes how a systematic, logical approach to environmental assessment can be applied to a variety of complex situations. Finally, the design and implementation of a more objective and powerful assessment is demonstrated through a worked example. Explanations of computational intelligence techniques and discussions of helpful software are intended to benefit those people actually preparing and using environmental assessments--in language that makes the process transparent and transferable to all types of systems.

Buch. Zustand: Neu. Neuware - This textbook and reference fills a critical gap in literature on the comprehensive environmental impacts of industrial organizations. Nineteen chapters examine individual industrial sectors inherent 'potential to pollute.' The text goes on to analyze new technologies and practices for transforming environmentally degrading effects of industry, and shows how managers can navigate these changes and move their organizations towards long-term environmental sustainability.

Taschenbuch. Zustand: Neu. Neuware - As everyone knows, intuition is warm and fuzzy, qualitative, not measurable. Economics, on the other hand, is quantitative, and if it is not a hard science, at least it is the 'queen of the social sciences.' It is, therefore, intuitively obvious, that intuition and economics are as if oil and water. The problem is, what is intuitively obvious is not always correct. And, there are two major reasons why intuition and economics are not like oil and water. First, economics concerns itself with decision making, and decisions are made in the brain. The human brain is the size of a grapefruit, weighing three pounds with approximately 180 billion neurons, each physically independent but interacting with the other neurons. What we call intuition is, like decision making, a natural information processing function of the brain. Second, despite the current emphasis on quantitative analysis and deductive logic there is a rich history of economists speaking about intuition. First, the human brain, specifically the neocortex, has a left and right hemisphere. The specialized analytical style of the left hemisphere and the specialized intuitive style of the right hemispheres complement each other.

Buch. Zustand: Neu. Neuware - Nuclear physics began one century ago during the 'miraculous decade' - tween 1895 and 1905 when the foundations of practically all modern physics were established. The period started with two unexpected spino s of the Crooke's vacuum tube: Roentgen's X-rays (1895) and Thomson's electron (1897), the rst elementary particle to be discovered. Lorentz and Zeemann developed the the theory of the electron and the in uence of magnetism on radiation. Quantum phenomenology began in December, 1900 with the - pearance of Planck's constant followed by Einstein's 1905 proposal of what is now called the photon. In 1905, Einstein also published the theories of relativity and of Brownian motion, the ultimate triumph of Boltzman's s- tistical theory, a year before his tragic death. For nuclear physics, the critical discovery was that of radioactivity by Becquerel in 1896. By analyzing the history of science, one can be convinced that there is some rationale in the fact that all of these discoveries came nearly sim- taneously, after the scienti cally triumphant 19th century. The exception is radioactivity, an unexpected baby whose discovery could have happened s- eral decades earlier. Talentedscientists,theCuries,Rutherford,andmanyothers,tookthe- servationofradioactivityandconstructedtheideasthatarethesubje ctofthis book. Of course, the discovery of radioactivity and nuclear physics is of much broader importance. It lead directly to quantum mechanics via Rutherford's planetary atomic model and Bohr's interpretation of the hydrogen spectrum. This in turn led to atomic physics, solid state physics, and material science.

Taschenbuch. Zustand: Neu. Neuware - Multiplicative noise appears in systems where the process or measurement noise levels depend on the system state vector. Such systems are relevant, for example, in radar measurements where larger ranges involve higher noise level.This monograph embodies a comprehensive survey of the relevant literature with basic problems being formulated and solved by applying various techniques including game theory, linear matrix inequalities and Lyapunov parameter-dependent functions.Topics covered include: convex H2 and H-infinity norms analysis of systems with multiplicative noise; state feedback control and state estimation of systems with multiplicative noise; dynamic and static output feedback of stochastic bilinear systems; tracking controllers for stochastic bilinear systems utilizing preview information. Various examples which demonstrate the applicability of the theory to practical control engineering problems are considered; two such examples are taken from the aerospace and guidance control areas.

Buch. Zustand: Neu. Neuware - Longitudinal data are ubiquitous across Medicine, Public Health, Public Policy, Psychology, Political Science, Biology, Sociology and Education, yet many longitudinal data sets remain improperly analyzed. This book teaches the art and statistical science of modern longitudinal data analysis. The author emphasizes specifying, understanding, and interpreting longitudinal data models. He inspects the longitudinal data graphically, analyzes the time trend and covariates, models the covariance matrix, and then draws conclusions.Covariance models covered include random effects, autoregressive, autoregressive moving average, antedependence, factor analytic, and completely unstructured models among others. Longer expositions explore: an introduction to and critique of simple non-longitudinal analyses of longitudinal data, missing data concepts, diagnostics, and simultaneous modeling of two longitudinal variables. Applications and issues for random effects models cover estimation, shrinkage, clustered data, models for binary and count data and residuals and residual plots. Shorter sections include a general discussion of how computational algorithms work, handling transformed data, and basic design issues.This book requires a solid regression course as background and is particularly intended for the final year of a Biostatistics or Statistics Masters degree curriculum. The mathematical prerequisite is generally low, mainly assuming familiarity with regression analysis in matrix form. Doctoral students in Biostatistics or Statistics, applied researchers and quantitative doctoral students in disciplines such as Medicine, Public Health, Public Policy, Psychology, Political Science, Biology, Sociology and Education will find this book invaluable. The book has many figures and tables illustrating longitudinal data and numerous homework problems. The associated web site contains many longitudinal data sets, examples of computer code, and labs to re-enforce thematerial. From the reviews: '.This book is extremely well presented and it has been written in a style that makes its reading really pleasant and enjoyable.I highly recommend Modeling Longitudinal Data as a good reference book for anyone interested in looking into the art and statistical science of modern longitudinal data analysis.' Journal of Applied Statistics, December 2005'The book is clearly written and well presented. The author's accumulated experience in presenting the material comes over. On balance, this is one of the books which anyone about to teach a practical course in longitudinal data analysis should consider adopting as the course text.' Short Book Reviews of the ISI, June 2006'.Modeling Longitudinal Data is a welcome addition to the vast literature on longitudinal data analysis. The book requires little in terms of prerequisites but offers a great deal.' Zhigang Zhang for the Journal of the American Statistical Association, December 2006'Overall, Robert Weiss's book can be used as an excellent textbook for a first master-level course in longitudinal data analysis in a statistics or biostatistics program, or as a self-study book for applied researchers interested in this area.The style is very clear, concepts are explained in an engaging way and amply illustrated, and the chapters on covariate selection and modeling the variance-covariance matrix are definite assets.' Ralitza Gueorgueiva for Biostatistics, September 2006.

Taschenbuch. Zustand: Neu. Neuware -Analysis III. Applications, and IV. Contest: Social Milieus in Dortmund.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 704 pp. Englisch.

Buch. Zustand: Neu. Neuware - Several years ago, when the discovery of catalytic RNA was recognized in a public manner,many people asked if new elds of therapy would soon be available. Although some tentative positive answers were given,nobody would say with certainty that RNA of various kinds was a truly promising means of altering gene expression. In fact,over the past decade,both our knowledge of RNAs with different functions and the utility of RNA in the inhibition or enhancement of gene expression have occurred with great drama. We proceeded in terms of possible therapeutic tools from RNase P and group I introns through hammerhead RNA enzymes, antisense technology, and more recently, to RNAi and its derivatives. A useful practical method of RNA delivery in animals will complete the picture. The diversity of RNA and the varied role of it inside cells and in therapy should be a tremendous challenge for young molecular biologists. This volume will make their task easier. Sidney Altman Sterling Professor of Molecular,Cellular & Devel- mental Biology,Nobel Laureate Department of Molecular,Cellular and Developm- tal Biology Yale University V NGTPR 4/23/05 1:00 PM Page VI VI Foreword Delivery of nucleic acids to cells in an animal remains a challenging problem. It is the major obstacle to success of therapeutic approaches using genes and oli- nucleotides,including siRNAs. Solutions found so far by chemists are satisfactory only for transfection of cells in culture.

Taschenbuch. Zustand: Neu. Neuware - This volume contains revised versions of selected papers presented during the 28th Annual Conference of the Gesellschaft fur Klassi kation (GfKl), the German Classi cation Society. The conference was held at the Universit at Dortmund in Dortmund, Germany, in March 2004. Wolfgang Gaul chaired the program committee, Claus Weihs and Ernst-Erich Doberkat were the local organizers. Patrick Groenen, Iven van Mechelen, and their colleagues of the Vereniging voor Ordinatie en Classi catie (VOC), the Dutch-Flemish Classi cation Society, organized special VOC sessions. The programcommittee recruited17 notable and internationallyreno- ed invited speakers for plenary and semi-plenary talks on their current - search work regarding classi cation and data analysis methods as well as - plications.Inaddition,172invitedandcontributedpapersbyauthorsfrom18 countrieswerepresentedatthe conferencein 52parallelsessionsrepresenting the whole eld addressed by the title of the conference Classi cation: The Ubiquitous Challenge . Among these 52 sessions the VOC organizedsessions on Mixture Modelling, Optimal Scaling, Multiway Methods, and Psychom- ricswith18papers.Overall,theconference,whichistraditionallydesignedas an interdisciplinary event, again provided an attractive forum for discussions and mutual exchange of knowledge. Besides the results obtained in the fundamental subjects Classi cation and Data Analysis, the talks in the applied areas focused on various app- cation topics. Moreover, along with the conference a competition on Social Milieus in Dortmund , co-organized by the city of Dortmund, took place. Hence the presentation of the papers in this volume is arranged in the f- lowing parts: I. (Semi-)Plenary Presentations II. Classi cation and Data Analysis III. Applications, and IV. Contest: Social Milieus in Dortmund.

Buch. Zustand: Neu. Neuware - Modelling and Control of Mini-Flying Machinesis an exposition of models developed to assist in the motion control of various types of mini-aircraft:- Planar Vertical Take-off and Landing aircraft;- helicopters; - quadrotor mini-rotorcraft; - other fixed-wing aircraft; - blimps. For each of these it propounds: - detailed models derived from Euler-Lagrange methods; - appropriate nonlinear control strategies and convergence properties;- real-time experimental comparisons of the performance of control algorithms;- review of the principal sensors, on-board electronics, real-time architecture and communications systems for mini-flying machine control, including discussion of their performance;- detailed explanation of the use of the Kalman filter to flying machine localization.To researchers and students in nonlinear control and its applications Modelling and Control of Mini-Flying Machines provides valuable insights to the application of real-time nonlinear techniques in an always challenging area.

Buch. Zustand: Neu. Neuware - The idea of preparing a new critical edition of Elisha Bartlett's Essay on the Philosophy of Medical Science was suggested to me several years ago by Dr. H. Tristram Engelhardt, Jr. Since that time it has been a pleasure to get to know the life and work of Elisha Bartlett. I am pleased to be completing this book in the bicentennial year of Bartlett's birth. Bartlett was born in 1804 in Smithfield, Rhode Island, less than twenty-five miles from Worcester, Massachusetts, my present home-a short journey even in Bartlett's day. I have been able to walk at some of the sites to which Bartlett continually returned during his life. Visiting Bartlett's grave in the Slatersville cemetery has been an inspiration for the preparation of this book. Proximity to several institutions with rich holdings in Bartlett's works and in nineteenth-century American history of medicine greatly facilitated my research. First, though, I want to acknowledge the College of the Holy Cross for supporting my sabbatical leave for the academic year 2003-2004. The American Antiquarian Society, in Worcester, Massachusetts, was generous in giving me access to its remarkable resources. I was able to find many of Bartlett's published works and other nineteenth-century medical literature there, and the entire library staff provided quick and able research assistance.

Taschenbuch. Zustand: Neu. Neuware - An in-depth introduction to subspace methods for system identification in discrete-time linear systems thoroughly augmented with advanced and novel results, this text is structured into three parts.Part I deals with the mathematical preliminaries: numerical linear algebra; system theory; stochastic processes; and Kalman filtering. Part II explains realization theory as applied to subspace identification. Stochastic realization results based on spectral factorization and Riccati equations, and on canonical correlation analysis for stationary processes are included. Part III demonstrates the closed-loop application of subspace identification methods.Subspace Methods for System Identification is an excellent reference for researchers and a useful text for tutors and graduate students involved in control and signal processing courses. It can be used for self-study and will be of interest to applied scientists or engineers wishing to use advanced methods in modeling and identification of complex systems.

Buch. Zustand: Neu. Neuware - As more people worldwide live in cities, increasingly we need to understand how cities and city living affect population health. Does city living negatively affect health Conversely, can city living enhance population health and well-being Over forty experts from around the world bring a depth of ideas to the Handbook of Urban Health, making the Handbook a focused resource for a range of health disciplines. The Handbook presents: (1) A discussion of the health of specific urban populations, among them immigrants, children, the elderly, racial and sexual minorities, the homeless, and the poor. (2) Methods relevant to the study of urban health including epidemiology, research methods, funding and policy issues, urban planning. (3) Practical issues for developing healthy cities including interventions, preventive strategies, providing health services, and teaching urban health. (4) International perspectives from developing countries and the World Health Organization. (5) Integrative chapters that conclude each of the book's sections, bringing together theoretical models with the big picture.A unique professional idea book, research resource, and teaching text, the Handbook of Urban Health challenges readers to consider the role that cities play in shaping population health and to generate solutions that can make cities healthier places for all those who live there.

Buch. Zustand: Neu. Neuware - Knowledge Management and Data Mining in Biomedicine covers the basic foundations of the area while extending the foundational material to include the recent leading-edge research in the field. The newer concepts, techniques, and practices of biomedical knowledge management and data mining are introduced and examined in detail. It is the research and applications in these areas that are raising the technical horizons and expanding the utility of informatics to an increasing number of biomedical professionals and researchers. These concepts and techniques are illustrated with detailed case studies.

Buch. Zustand: Neu. Neuware - On April 29, 2003, the Zicklin School of Business hosted a trading conference titled, Coping With Institutional Order Flow. This conference was electronically recorded and later transcribed for this book. The text includes the edited transcript of the panel discussions and separate presentations by two major industry executives, Richard Ketchum' and Robert Mc Sweeney. As with the other volumes in this popular series, this book is not simply intended to be an historical record of the conference. We have edited the manuscript for clarity, perspective and context. New material was gathered in subsequent interviews with many of the panelists. Consequently, some remarks and passages in the text were altered and expanded and many footnotes were introduced. Our goal was to flesh out the dialogue and presentations and to keep the material as contemporary as possible. In doing so, we went to great lengths to preserve the essential nature of the original debate. We worked closely with the panelists in the editing process and took pains not to distort the meaning of their remarks. They have all approved the final draft of the manuscript. We thank them for their assistance and patience.my opening remarks at the conference, I suggested that effective handling of institutional order flow is one of the most important and difficult At the time of the conference, Richard Ketchum was President and Deputy Chairman at The Nasdaq Stock Market, Inc. Preface xiv challenges facing our equity markets today.

Buch. Zustand: Neu. Neuware - This book nds new things to do with an old idea. The proofs-as-programs paradigm constitutes a set of approaches to developing programs from proofs in constructive logic. It has been over thirty years since the paradigm was rst conceived. At that time, there was a belief that proofs-as-programs had the - tential for practical application to semi-automated software development. I- tial applications were mostly concerned with ne-grain, mathematical program synthesis. For various reasons, research interest in the area eventually tended toward more theoretic issues of constructive logic and type theory. However, in recent years, the situation has become more balanced, and there is increasingly active research in applying constructive techniques to industrial-scale, complex software engineering problems. Thismonographdetailsseveralimportantadvancesinthisdirectionofpr- tical proofs-as-programs. One of the central themes of the book is a general, abstract framework for developing new systems of program synthesis by adapting proofs-as-programs to new contexts. Framework-oriented approaches that facilitate analogous - proaches to building systems for solving particular problems have been popular and successful. Thesemethodsarehelpful asthey providea formal toolbox that enablesa'roll-your-own'approachtodevelopingsolutions.Itishopedthatour framework will have a similar impact. The framework is demonstrated by example. We will give two novel - plications of proofs-as-programs to large-scale, coarse-grain software engine- ing problems: contractual imperative program synthesis and structured p- gram synthesis. These applications constitute an exemplary justi cation of the framework. Also, in and of themselves, these approaches to synthesis should be interesting forresearchers working in the target problem domains.

Buch. Zustand: Neu. Neuware - Humans contain more than 20 Rho type GTPases. This volume not only presents a detailed phylogenetic analysis of Rho proteins, but also discusses the possible origins of the human members. Such an analysis of human Rho GTPases has not previously been attempted.The book includes an overview of how Rho GTPases become activated which is complemented by an extensive Chapter by Darerca Owen and Helen Mott who unravel the beautiful molecular details given to us by the many structural studies of Rho GTPases.The key areas currently being investigated in relation to these ubiquitous proteins are described for both in vitro and in vivo systems. These are presented in a format that ensures the reader can approach the topic with minimal background knowledge, while ultimately bringing the subject to the level of an expert. Timely and highly authoritative, this volume illuminates newer findings, particularly as they relate to Rho proteins in vertebrate biology.

Buch. Zustand: Neu. Neuware - Modern society depends critically on computers that control and manage the systems on which we depend in many aspects of our daily lives. While this provides conveniences of a level unimaginable just a few years ago, it also leaves us vulnerable to attacks on the computers managing these systems. In recent times the explosion in cyber attacks, including viruses, worms, and intrusions, has turned this vulnerability into a clear and visible threat. Due to the escalating number and increased sophistication of cyber attacks, it has become important to develop a broad range of techniques, which can ensure that the information infrastructure continues to operate smoothly, even in the presence of dire and continuous threats.This book brings together the latest techniques for managing cyber threats, developed by some of the world s leading experts in the area. The book includes broad surveys on a number of topics, as well as specific techniques. It provides an excellent reference point for researchers and practitioners in the government, academic, and industrial communities who want to understand the issues and challenges in this area of growing worldwide importance.