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Taschenbuch. Zustand: Neu. Neuware -This volume of essays grew out of a symposium organized by Judith Hoch-Smith and Anita Spring for the 1974 American Anthropological Association meetings in Mexico City. The two-part symposium was enti tled 'Women in Ritual and Symbolic Systems: I. Midwives, Madonnas, and Mediums; ll. Prostitutes, Witches, and Androgynes. ' The sym posium participants were asked to explore theological, ritual, and sym bolic aspects-both positive and negative-of the feminine cultural do main, using ethnographic materials with which they were familiar. The resulting papers have been revised, edited, and gathered together in Women in Ritual and Symbolic Roles. The theoretical importance of these papers for the study of women's participation in culture and society rests on the assumption that reli gious ideas are paramount forces in social life, that relationships be tween the sexes, the nature of female sexuality, and the social and cul tural roles of women are in large part defined by religious ideas. That this proposition remains valid long after religion itself has ceased to be a living truth in the lives of many people can be seen from the tenacious ness of Judeo-Christian ideas about women in the contemporary West ern world. Both the expansion of life options for women and the creation of more positive cultural images of the female are intimately related to changes in the my tho-symbolic portraits that people carry around in their heads. These portraits are almost exclusively constructed from mythological and religious conceptions inherent in all facets of culture.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 308 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware - Recent advances in the field of recombinant antibodies have permitted the manipulation of genes encoding specific antibodies, thus allowing their ectopic expression in a wide variety of non-lymphoid cells. This volume describes how the ectopic expression of antibodies, as secreted or as intracellularly retargeted molecules, can be exploited to block biological functions or to confer new phenotypic traits (e.g. resistance to a virus). This is the first book describing this emerging technology, which is receiving increasing attention for application in many different fields and biological systems - from human gene therapy to plant biotechnology.

Taschenbuch. Zustand: Neu. Neuware - This volume of essays grew out of a symposium organized by Judith Hoch-Smith and Anita Spring for the 1974 American Anthropological Association meetings in Mexico City. The two-part symposium was enti tled 'Women in Ritual and Symbolic Systems: I. Midwives, Madonnas, and Mediums; ll. Prostitutes, Witches, and Androgynes. ' The sym posium participants were asked to explore theological, ritual, and sym bolic aspects-both positive and negative-of the feminine cultural do main, using ethnographic materials with which they were familiar. The resulting papers have been revised, edited, and gathered together in Women in Ritual and Symbolic Roles. The theoretical importance of these papers for the study of women's participation in culture and society rests on the assumption that reli gious ideas are paramount forces in social life, that relationships be tween the sexes, the nature of female sexuality, and the social and cul tural roles of women are in large part defined by religious ideas. That this proposition remains valid long after religion itself has ceased to be a living truth in the lives of many people can be seen from the tenacious ness of Judeo-Christian ideas about women in the contemporary West ern world. Both the expansion of life options for women and the creation of more positive cultural images of the female are intimately related to changes in the my tho-symbolic portraits that people carry around in their heads. These portraits are almost exclusively constructed from mythological and religious conceptions inherent in all facets of culture.

Taschenbuch. Zustand: Neu. Neuware - This volume contains a selection of scientific papers related to the structure and dynamics of non-rigid molecules. This frontline topic was born a few decades ago, when Longuet-Higgins proposed his famous theory of Molecular Symmetry Groups (Mol. Phys. 6, (1962) 457). Unfortunately, since this early paper, very few publications have been devoted to the study of non-rigid molecules. Let us mention some books which dedicate some chapters to them: Induced Representations in Crystals and Molecules, by S. L. Altmann, Academic Publishers, 1977; Molecular Symmetry and Spectroscopy, by P. R. Bunker, Academic Publishers, 1979; and finally Large Amplitude Motion in Molecules, Vols. I and II, by several authors, Springer Verlag, 1979. More recently an International Symposium on Non-Rigid Molecules was held in Paris, France, from 1-7 July 1982, the proceedings of which were published in the volume entitled Symmetries and Properties of Non-Rigid Molecules. A Comprehensive Survey, edited by J. Maruani et al., Elsevier, 1983. Finally, we should mention the very specialized work The Permutational Approach to Dynamic Stereochemistry, by J. Brocas et al., McGraw-Hill, 1983. The purpose of this book is to fill in this information on the structure and dynamics of non-rigid systems. To this aim, we have gathered a collection of recent papers written by the most qualified specialists in the world, covering a large field from van der Waals molecules to inorganic complexes and organic polyrotor molecules, as well as considering statistical and dynamic aspects.

Taschenbuch. Zustand: Neu. Neuware - This book contains the collected papers presented at the Inter national Symposium on Polymers in Medicine, Biomedical and Pharma cological Applications, which was held at Porto Cervo, Italy, May 24-28, 1982. To the best of our knowledge, this symposium was the first to be organized in Italy entirely devoted to the several aspects of the use of synthetic and semisynthetic macromolecular materials in the field of biomedical and pharmacological applications. The inten~ tion of the Organizing Committee of the symposium was the promotion of a scientific and cultural initiative to gain the attention of various experts in line research of the potential of suitably de signed 'man-made' polymeric materials in biomedical applications. With highly qualified and worldwide attendance, the above goal was fully satisfied. Indeed the opportunity of meeting to gether in a well conceived and discreet corner of the world, scien tists with different cultural backgrounds and objectives helped ex tend the meaning of the symposium far beyond the Italian borders and the perspectives of the National Research Council of Italy (CNR) , the major sponsor of the meeting.

Taschenbuch. Zustand: Neu. Neuware - Despite an enormous investment of effort throughout the world, cancer is still a major barrier to human longevity. Cancer deaths are estimated to be more than five million globally. Currently responsible for about 20% of all deaths in developed coun tries, the burden of cancer is steadily increasing in the developing world, following the control of malnutrition and infectious and parasitic diseases. Deeply impressed by the report of the Symposium on Geographic Pathology and Demography of Cancer held at Oxford in 1950, and through his preliminary work on cancer mortality statistics in Japan, Professor M. Segi decided to devote his life to the fight against cancer by establishing worldwide comparative cancer statistics-one of the landmarks in cancer studies and in cancer prevention strategies. He and his associates published six volumes of Cancer Mortality in 24 Countries with reliable mortality statistics covering 1950-1967, using the world population which he had derived as a standard. These publications rapidly became standard works of reference on the subject throughout the world. Professor Segi was a pioneer of cancer epidemiology in Japan. He cleaved a path through the jungle of cancer using epidemiological methods. By promoting cancer studies, he overcame the poor understanding of malignant disease which existed after World War II, when cancer mortality rates were still low.

Taschenbuch. Zustand: Neu. Neuware - That residues of pesticide and other 'foreign' chemicals in foodstuffs are of concern to everyone everywhere is amply attested by the reception accorded previous volumes of 'Residue Reviews' and by the gratifying en thusiasm, sincerity, and efforts shown by all the individuals from whom manuscripts have been solicited. Despite much propaganda to the contrary, there can never be any serious question that pest-control chemicals and food additive chemicals are essential to adequate food production, manufacture, marketing, and storage, yet without continuing surveillance and intelligent control some of those thalt persist in our foodstuffs could at times conceivably endanger the public health. Ensuring safety-in-use of these many chemicals is a dynamic challenge, for established ones are continually being displaced by newly developed ones more acceptable to food technologists, pharma cologists, toxicologists, and changing pest-control requirements in progressive food-producing economies. These matters are also of genuine concern to increasing numbers of governmental agencies and legislative bodies around the world, for some of these chemicals have resulted in a few mishaps from improper use. Adequate safety-in-use evaluations of any of these chemicals persisting into our food stuffs are not simple matters, and they incorporate the considered judgments of many individuals highly trained in a variety of complex biological, chemi cal, food technological, medical, pharmacological, and toxicological disciplines.

Taschenbuch. Zustand: Neu. Neuware - Advances in Microbial Ecology was established by the International Commis sion on Microbial Ecology to provide a vehicle for in-depth, critical, and, it is hoped, provocative reviews on aspects of both applied and basic microbial ecol ogy. In the five years of its existence, Advances has achieved recognition as a major source of information and inspiration both for practicing and f.

Taschenbuch. Zustand: Neu. Neuware - That residues of pesticide and other contaminants in the total environment are of concern to everyone everywhere is attested by the reception accorded previous volumes of 'Residue Reviews' and by the gratifying enthusiasm, Sincerity, and efforts shown by all the in dividuals from whom manuscripts have been solicited. Despite much propaganda to the contrary, there can never be any serious question that pest-control chemicals and food-additive chemicals are essential to adequate food production, manufacture, marketing, and storage, yet without continuing surveillance and intelligent control some of those that persist in our foodstuffs could at times conceivably endanger the public health. Ensuring safety-in-use of these many chemicals is a dynamic challenge, for established ones are continually being dis placed by newly developed ones more acceptable to food tech nologists, pharmacologists, toxicologists, and changing pest-control requirements in progressive food-producing economies. These matters are of genuine concern to increasing numbers of governmental agencies and legislative bodies around the world, for some of these chemicals have resulted in a few mishaps from improper use. Adequate safety-in-use evaluations of any of these chemicals per sisting into our foodstuffs are not simple matters, and they incorporate the considered judgments of many individuals highly trained in a variety of complex biolOgical, chemical, food technological, medical, pharmacological, and toxicological disciplines.

Taschenbuch. Zustand: Neu. Neuware - 1 The Chondrodystrophies.- Classification of the Chondrodystrophies.- Evaluation of the Dwarfed Patient.- Clinical, Radiographic, Genetic, and Pathological Features of the Chondrodystrophies.- Animal Models of the Chondrodystrophies.- Future Trends in Chondrodystrophy Research.- 2 New Techniques in the Study of Human Chromosomes: Methods and Applications.- Fluorescence Microscopy.- Giemsa Staining.- The Usage of Banding Techniques.- Abnormalities Detected by Banding Analysis.- Chemical Properties of the Bands.- Technical Appendix.- 3 The Thalassemias: Models for Analysis of Quantitative Gene Control.- History.- Definition.- Organization of Globin Genes.- Ontogeny of Hemoglobin Production.- Inheritance of Thalassemia.- Frequency of Thalassemia.- Regulation of Hemoglobin Synthesis and Turnover.- Transcription of Hemoglobin Genes.- Intranuclear Processing of the Primary Gene Product.- Transport of Messenger RNA to the Cytoplasm.- Cytoplasmic Metabolism of Messenger RNA.- Balance of Hemin and Globin (Protein) Synthesis in Reticulocytes.- Other Steps in Hemoglobin Synthesis and Degradation.- Pathophysiology of the Thalassemias.- Directions in Therapy.- Note Added in Proof.- 4 Spontaneous Mutation in Man.- 'Classical' Mutation Rates.- Molecular Aspects of Human Mutation.- Spontaneous Mutation in Other Organisms and Its Significance for the Understanding of Human Mutations.- 5 Genetic Screening Legislation.- The Public Health Power.- Legislation Mandating Detection of Genetic Disease.- Legislation Mandating Screening for Genetic Traits.- Future of State-Supported Genetic Screening.

Taschenbuch. Zustand: Neu. Neuware - Three articles make up Volume 10 of Methods in Membrane Biology. In the first of these, Papahadjopoulos, Poste, and Vail extensively review much of the available data on the fusion of natural membranes, model membranes (liposomes), and natural membranes with liposomes. The authors are led by their review of the experimental methods and their interpretations of the results obtained to a general theory of membrane fusion which they believe is applicable to all systems that have been studied. Arguing that although protein and carbohydrate may serve, in some cases, to bring membranes into sufficiently close proximity for fusion to occur and, in other cases, to remove peripheral and integral proteins from the regions that are to undergo fusion, the authors conclude that membrane fusion per se is solely a property of the lipid bilayer. In their view, all the experimental observations to date can be subsumed under a unifying hypothesis in which membrane fusion is the result of a phase separation in one-half of the membrane bilayer brought about by the interaction - of calcium ions with acidic phospholipids, mostly phosphatidylserine. Where half-membranes already contain sufficient acidic phospholipids, a local increase in calcium ion concentration may suffice to induce fusion (examples might include exocytosis and fusion of intracellular membrane systems). In other cases, natural or experimentally induced events preceding fusion might be necessary to increase the local concentration of the acidic phospholipids in the half-membrane (virus-or fusogenic agent-induced cell-to-cell fusion, or endocytosis, for example).

Taschenbuch. Zustand: Neu. Neuware - This is the third volume in the series of books based on the Annual Merseyside Course in Clinical Psychology. In common with its predecessors its aim is to present a number of topics of interest to practitioners, researchers, trainers and trainees in the field, with the intent not only to inform but variously also to question and to guide further enquiry. Selection for this volume has taken a somewhat different stance to the previous two. Whereas in former volumes an attempt has been made to cover standard areas of general and scientific interest to psychologists and others in related professions, such as anorexia nervosa, forensic issues, long term care, mental handicap, community psychology, anxiety and de pression, in this one issues which are of equal relevance but not necessarily of equal prominence in psychological texts, are included. We have not, however, neglected those areas more readily recognized as of major clinical import which are being progressively covered in this series. This year we have the section 'Bereavement and the Care of the Dying'. Although for many this may not be a main focus, it is a subject that few helpers do not encounter either directly or indirectly with their clients. It would be impossible for this subject to not reflect the most human side of the caring professions, and it is perhaps in this field that the objective/subjective dilemma of the clinician can be seen in its most acute form.

Taschenbuch. Zustand: Neu. Neuware - Advances in Clinical Child Psychology is. a serial publication designed to bring together original summaries of the most important new develop ments in the field of clinical child psychology and its related disciplines. Each chapter is written by a key figure in an innovative area of research or by an individual who is particularly well qualified to comment on a topic of major contemporary importance. These chapters provide con venient, concise explorations of empirical and clinical advances in the field. In Volume 6, the chapters reflect the changing nature of research on the disorders of children. Since the beginning of this series, increasing amounts of innovative and promising research have focused on the classification, etiology, and development of childhood psychopathol ogy. This volume contains chapters on the classification of autism, the nature of sexual abuse, the development of social deficiencies and affec tion, and the important variables of maternal depression, infant-child interactions, sibling interactions, and early temperament. This volume also highlights another significant trend in clinical child psychology-its increasing rapprochement with developmental psychology. A chapter on the importance of cognitive development in dictating child interview strategies is an important example of this trend. We appreciate the roles played by the advisory editors in suggesting excellent topics and thoughtfully editing the chapters. As always, our strongest thanks go to the volume's authors for their outstanding contributions.

Taschenbuch. Zustand: Neu. Neuware - Volume 9 of Developments in Applied Spectroscopy pr e sents a collection of tventy-three selected papers presented during the 21st Mid-America Symposium on Spectroscopy, held in Chicago, June 2-5, 1970, In general. these papers are those of the symposium type and not papers pertaining to a specific research topic that one voul~ expect to find in the journals. The 21st Mid-America Symposium vas sponsored by the Chicago Section in cooperation vith Cincinnati, Cleveland, Indiana, Nev England, Nev York, Niagara Frontier and Ohio Vall ey Sections of the Society of Applied Spectroscopy, and the Chicago Gas Chromatography Group. Although the Mid America is stiIl occasionally thought of as a regional meet ing, its attendees and authors come from all parts of the United States and Canada as vell as other countries outside North America. Both theoretieal and applied principles vere presented in sessions on emission, molecular and atomic absorption, x-ray, mass, nuclear, electron, and nuclear magnetic and electron spin resonanee spectroscopy; air and Water pOllution analyses; biomedical technology; polymers and elastomeric materials; and computer applications. The chairmen of the Symposium Committees, Mr. E. Baclavski. Dr. W. K. Baer, Mr. J. E. Burroughs, Dr. C. R. Brundle, Mr. C. Hastings, Mr. J. B. Himes, Mr. R. Isaac, Dr. R. J. Jakobsen, Mr. J. Kinder, Dr. J. L. Koenig, Mr. W. A. Loseke, Dr. R. Mattoon, Miss V. McMahon, Dr. C.E. Moore, Mr. C. S. Naiman, Dr. M. J. Oestmann, Mr. C. R.

Taschenbuch. Zustand: Neu. Neuware - The Laser Raman Workshop on the r'eas urement of Gas Properti es i sone of aseries of occasional meetings organized in an informal workshop format through the stimulation of Project SQUID, Office of Naval Research. This workshop is the second to be organized on gas-phase applications of Raman scattering. Both Raman workshops were supported by Project SQUID, ONR, and the Air Force Aero Propulsion Laboratory, Wright-Patterson Air Force Base. The first Raman Workshop was held at the AVCO Everett Research Laboratory, Everett, Massachusetts, with their co-sponsorship in January 1972 under the chairmanship of D. A. Leonard. The present meeting was co-sponsored by the General Electric Research and Development Center, and held at their facility in Schenectady, New York. We are grateful to Project SQUID, AFAPL, and GE for their generous financial support of this Workshop, and to Project SQUID for underwriting the publication costs of the Proceedings. As is always the case for successful meetings, many people contributed substantially to the organization and execution of this workshop. Professor Robert Goulard supported, aided, and encouraged us in the most helpful ways, and we are indebted to him. We received further valuable support and assistance from Dr. Ralph Roberts, Director, and Mr. James R. Patton, Jr., of the Power Branch, Office of Naval Research; from Dr. William H. Heiser, Chief Scientist of the Aero Propulsion Laboratory; and from Dr. James M.

Taschenbuch. Zustand: Neu. Neuware - The contemporary economic landscape features the prevalence of the service sector in economic systems, the pervasive servitisation of manufacturing, innovations in traditional business models and new value creation models, thanks to the new possibilities offered by the web, ICT and other enabling technologies. In this evolving context, this book provides qualified contributions on the topic of service science from a managerial perspective. A multidisciplinary perspective is adopted, dealing with both the structural-technological and dynamic-relational aspects of managing complexity. In addressing the contribution that service science can make to business value creation, this book covers relevant issues such as product servitisation, business modelling, value cocreation with customers, performance measures and the role of ICT. It also presents some innovative experiences of management models in service organisations operating in the environmental, energy and health-care sectors. This book aims to enhance the value of the results of research intertwined with the development of a new training curriculum started four years ago at the Scuola Superiore Sant'Anna of Pisa (Italy) with the evolution of the 'Master in Management of Innovation' into the new 'Master in Management, Innovation and Service Engineering' (MAINS).

Taschenbuch. Zustand: Neu. Neuware - Young People's Human Rights and The Politics of Voting Age explores the broader societal implications of voting age eligibility requirements and the legislative bar against youth voting in North America and in Commonwealth countries (where 'youth' is defined as persons 16 and over but under age 18). The issue is raised as to whether the denial of the youth vote undermines democratic principles and values and ultimately the human dignity of youth. This is the first book to address the topic of the youth vote in-depth as a fundamental human rights concern relating to the entitlement in a democracy to societal participation and inclusion in influencing policy and law which profoundly affects one's life. Also examined are international perspectives on the issue of voting age eligibility. The book would be extremely valuable for instructional purposes as one of the primary texts in undergraduate or graduate courses on children's human rights, political psychology, political science , sociology of law or society and as a supplementary text for courses on human rights or constitutional law and would be of interest also to members of the general public concerned with children's human rights issues.

Taschenbuch. Zustand: Neu. Neuware -This volume of essays grew out of a symposium organized by Judith Hoch-Smith and Anita Spring for the 1974 American Anthropological Association meetings in Mexico City. The two-part symposium was enti tled 'Women in Ritual and Symbolic Systems: I. Midwives, Madonnas, and Mediums; ll. Prostitutes, Witches, and Androgynes. ' The sym posium participants were asked to explore theological, ritual, and sym bolic aspects-both positive and negative-of the feminine cultural do main, using ethnographic materials with which they were familiar. The resulting papers have been revised, edited, and gathered together in Women in Ritual and Symbolic Roles. The theoretical importance of these papers for the study of women's participation in culture and society rests on the assumption that reli gious ideas are paramount forces in social life, that relationships be tween the sexes, the nature of female sexuality, and the social and cul tural roles of women are in large part defined by religious ideas. That this proposition remains valid long after religion itself has ceased to be a living truth in the lives of many people can be seen from the tenacious ness of Judeo-Christian ideas about women in the contemporary West ern world. Both the expansion of life options for women and the creation of more positive cultural images of the female are intimately related to changes in the my tho-symbolic portraits that people carry around in their heads. These portraits are almost exclusively constructed from mythological and religious conceptions inherent in all facets of culture. 308 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -This book contains the collected papers presented at the Inter national Symposium on Polymers in Medicine, Biomedical and Pharma cological Applications, which was held at Porto Cervo, Italy, May 24-28, 1982. To the best of our knowledge, this symposium was the first to be organized in Italy entirely devoted to the several aspects of the use of synthetic and semisynthetic macromolecular materials in the field of biomedical and pharmacological applications. The inten~ tion of the Organizing Committee of the symposium was the promotion of a scientific and cultural initiative to gain the attention of various experts in line research of the potential of suitably de signed 'man-made' polymeric materials in biomedical applications. With highly qualified and worldwide attendance, the above goal was fully satisfied. Indeed the opportunity of meeting to gether in a well conceived and discreet corner of the world, scien tists with different cultural backgrounds and objectives helped ex tend the meaning of the symposium far beyond the Italian borders and the perspectives of the National Research Council of Italy (CNR) , the major sponsor of the meeting. 432 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -Despite an enormous investment of effort throughout the world, cancer is still a major barrier to human longevity. Cancer deaths are estimated to be more than five million globally. Currently responsible for about 20% of all deaths in developed coun tries, the burden of cancer is steadily increasing in the developing world, following the control of malnutrition and infectious and parasitic diseases. Deeply impressed by the report of the Symposium on Geographic Pathology and Demography of Cancer held at Oxford in 1950, and through his preliminary work on cancer mortality statistics in Japan, Professor M. Segi decided to devote his life to the fight against cancer by establishing worldwide comparative cancer statistics-one of the landmarks in cancer studies and in cancer prevention strategies. He and his associates published six volumes of Cancer Mortality in 24 Countries with reliable mortality statistics covering 1950-1967, using the world population which he had derived as a standard. These publications rapidly became standard works of reference on the subject throughout the world. Professor Segi was a pioneer of cancer epidemiology in Japan. He cleaved a path through the jungle of cancer using epidemiological methods. By promoting cancer studies, he overcame the poor understanding of malignant disease which existed after World War II, when cancer mortality rates were still low. 240 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware - J VERKAUFSKATEGORIE 0 e This text offers a clear, efficient exposition of Galois Theory with exercises and complete proofs. Topics include: Cardano's formulas; the Fundamental Theorem; Galois' Great Theorem (solvability for radicals of a polynomial is equivalent to solvability of its Galois Group); and computation of Galois group of cubics and quartics. There are appendices on group theory and on ruler-compass constructions. Developed on the basis of a second-semester graduate algebra course, following a course on group theory, this book will provide a concise introduction to Galois Theory suitable for graduate students, either as a text for a course or for study outside the classroom.

Taschenbuch. Zustand: Neu. Neuware - It is an honor and pleasure for me to write the foreword of this book comprising the of Forest Resources for proceedings of the Fourth Symposium on the Improvement Recyclable Forest Products. The symposium was organized by Dr. Toshihiro Ona, Associate Professor at the Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, Japan, as part of the 'Development of Forest Resources with High Performance for Paper Recycling' research project. This was supported by the Core Research for Evolutional Science and Technology (CREST) team at the Japan Science and Technology Agency Foundation (lST) and by Kyushu University. As a colleague of Dr. Ona, I commend his efforts in organizing the symposium and editing this book. In the forest, there is a multitude of resources, including trees, herbal plants, fruits, fungi, mammals, birds, insects, fishes, reptiles, water, landscapes, and tourist attractions. Nowadays, even the environment is regarded as a kind of forest resource. These resources can provide a diversity of forest products, such as timber for buildings, pulp and paper, charcoal, herbal medicines, wild vegetables, animal protein, edible mushrooms, and nonwoody fibers. From these resources, major forest products are produced using various species of trees. For example, softwood is suitable as building material, while hardwood is suitable for furniture production; pulp and paper are produced from both softwood and hardwood. Therefore, forest locations and forest management methods should vary according to the tree species used for production of different forest products.

Taschenbuch. Zustand: Neu. Neuware - Sociobiology is the play of the season. Its success is mellsured by its immense popularity and perhaps by the controversy it has generated as well. Unfortunately, neither its popularity nor the resulting controversy seems likely to assure progress toward understanding sociobiological issues. The play has too many actors and, it seems, the casting has been poor; the players are unable to maintain their roles. At center stage, of course, is E. O. Wilson and his monumental opus Sociobiology. 1 In the wings, and making periodic entrances, are an assort ment of brilliant, committed, and aggressive adversaries. On cue, one of them steps out and decries the self-fulfilling nature of sociobiological prophesies. The arguments of the adversaries are varied. They warn that if all nonhuman primate societies tolerate aggression and man is also a pri mate, then aggression may come to be considered 'normal' and therefore acceptable. Their dire warnings may also have real impact on policy, alter ing, for example, a research program intended to examine longitudinally the relation between a supernumerary chromosome and certain behavioral disorders. The rationale is that since the afflicted infants would have to be identified and the study obviously does assume that psychopathology is linked to the chromosome aberration, the attitudes of the child's parents could well contribute to abnormal behavior that might otherwise not appear.

Taschenbuch. Zustand: Neu. Neuware - The proceedings of a workshop conference are presented in this volume entitled Hypothalamic Peptide Hormones and Pituitary Regulation. The workshop was held in Wilson Hall on the campus of the National Institutes of Health, Bethesda, Maryland, during the days of November 1-2, 1976, and is the most recent of three symposia on neuroendocrinology that have been sponsored by the National Institutes of Health. The first one was held on December 6 - 8, 1961, in the New Everglades Hotel at Miami, Florida. During the first meeting, much emphasis was given to the anatomical and physiological basis for the fledgling science of neuroendocrinology. The proceedings of that symposium were published under the title of Advances in Neuroendocrinology, A. V. Nalbandov (ed. ), University of Illinois Press, Urbana, Illinois, 1963. The second workshop was held on January 8 -11, 1969, in the Arizona Inn at Tucson, Arizona, and was unique in several respects. It was evident to the participants that definitive identification and the determination of the chemical structure of at least one hypothalamic releasing factor was at hand (see Workshop Conference on Bioassay and Chemistry of the Hypophysio tropic Hormones of the Hypothalamus: ~Critical Evaluatioi'i':-J. Meites, ed. , The Williams and Wilkins Co. , Baltimore, Maryland, 1970). Much of what was presented at the second workshop was dedicated to methods of bioassay of the various releasing factors.

Taschenbuch. Zustand: Neu. Neuware.

Taschenbuch. Zustand: Neu. Neuware - This volume contains the edited transcript of an interdisci plinary colloquium held at Totts Gap Medical Research Laboratories, Bangor, Pennsylvania on October 12-14, 1983 under the sponsorship of the Muscular Dystrophy Association. The aim was to illuminate the pathogenic mechanism of Duchenne Muscular Dystrophy through a synthesis of available data on gene expression in muscle. In the informal give and take ot the collo quium, the participants found themselves engaged in mutual education and enlightenment as they attempted to put together what is known and to highlight what is not known about the subject. Significant research into muscle as a tissue and muscle disease began only about 50 years ago although the description of muscular dystrophy by Guillaume Benjamin Amand Duchenne de Boulogne had been published in 1862. By 1943 it was clear that Duchenne muscular dystrophy was an X-linked genetic disorder. Up to the present, however, the offending gene has not been identified although its location on the short arm of the X chromosome has been approximately determined. The gene product associated with the initial disturbance in skeletal muscle has also remained elusive up to now. Moreover, investigations into the mechanisms of the muscle degeneration have been hampered by ignorance of the fundamental phenotypic expression of the genetic disorder.

Taschenbuch. Zustand: Neu. Neuware - course, also aware that many who use this volume One in every three slides examined by a general diagnostic pathologist in the United Kingdom, and will be well familiar with the classical, or 'textbook', in most other countries, comes from a gynaecological appearances of most of the more common conditions patient. Few pathologists can hope, therefore, to and have therefore often chosen an example which, escape a constant exposure to gynaecological path whilst being typical, is not necessarily classical. ology, and it is the aim of this atlas to lessen the We have deliberately chosen not to include any difficulties of this diagnostic burden by acting as an illustrations of gross specimens. This is partly because illustrated guide to the histological diagnosis of of ou r view that such illustrations are of I ittle real value female genital tract abnormalities. to any but the least experienced of pathologists, and Gynaecological pathology does, however, pose a partly because their inclusion would have narrowed number of specific problems: the range and scope of still further our selection of histological figures.

Taschenbuch. Zustand: Neu. Neuware - This is not a textbook nor an encyclopedia; rather, it is a collection of papers representing a variety of points of view on contemporary is sues, controversies, and questions about female sexual development. The editor has a point of view, not a point of view as to which of the various authors' positions presented in this book is correct, or even the most useful, but a point of view about the format of such a book; namely, that the definitive answers, and the experts who will provide them, are not yet identified. Therefore, many voices should be heard from different areas of expertise, training, experience, and back ground. Inevitably there are contradictions and disagreements. There should be. Several authors who were asked to provide short discus sions for papers found themselves unable to answer in less than an ad ditional paper. The editor welcomed this response. This is an area full of ancient myths, new discoveries, and alternate perspectives. It is hoped that the book reflects these ambiguities and controversies and that it will stimulate as many questions as it provides answers. You will find represented in this volume, and its forthcoming companion volume on women's sexual experience, authors not gener ally found together between the covers. When useful and where pos sible, a discussion or an addendum to a paper has been included by an author who approaches the subject from a different base of infor mation or experience.

Taschenbuch. Zustand: Neu. Neuware - We are pleased to present Volume 9 of our highly successful series, which now celebrates 12 years of providing the magnetic resonance community with topical, authoritative chapters on new aspects of biological magnetic resonance. As always, we try to present a diversity of topic coverage in each volume, ranging from applications of in vivo magnetic resonance to more fundamental aspects of electron spin resonance and nuclear magnetic resonance. Philip Yeagle presents an eagerly awaited chapter on 31p NMR studies of membranes and membrane protein interactions. Alan Marshall has con tributed two chapters to the volume: one, with Jiejun Wu, describes magnetic resonance studies of 5S-RNA as probes of its structure and conformation; the secon.

Taschenbuch. Zustand: Neu. Neuware - Volume 4 of Advances in Nutritional Research reflects the increased importance that recently has been attached to nutrition in many fields of clinical medicine. This heightened interest in nutrition stems from the demonstration that the intake of specific nutrients may have far-reaching consequences, not only for normal metabolism, but also for metabolic processes affecting clinical or subclinical disease. Conversely, many disease states have been shown to have previously unrecognized effects on nutrient function and metabolism. In addition to topics of obvious relevance to human clinical nutrition, this volume contains chapters dealing with the nutrition of cells grown in culture and of species that may provide insights into nutritional disorders of man. To gether with its predecessors, Volume 4 provides graduate students and estab lished investigators with authoritative accounts of the status of research on a range of topics of current interest in experimental and clinical nutrition. vii Contents Chapter 1. Vitamin-Responsive Genetic Abnormalities . . S. Harvey Mudd 1. Introduction. 1 2. Historical Perspective . 2 3. Genetic Abnormalities Currently Known to Be Vitamin Responsive. 3 4. Mechanisms Underlying Vitamin Responsiveness. . . . . . . . . . . . . . . . 7 4.1. Defects in the Processing of a Vitamin Prior to Its Interaction in Cofactor Form with a Particular Apoenzyme . 7 4.2. Defects in Particular Apoenzymes that Interact with the Cofactor Forms of Vitamins. . . . . . . . . . . . . . . . . . 16 . . . . . .