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  • Anthony Young

    Verlag: Springer New York, Springer US Mär 2017, 2017

    ISBN 10: 1461461847 ISBN 13: 9781461461845

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Taschenbuch. Zustand: Neu. Neuware -This book focuses on the specific mission planning for lunar sample collection, the equipment used, and the analysis and findings concerning the samples at the Lunar Receiving Laboratory in Texas. Anthony Young documents the collection of Apollo samples for the first time for readers of all backgrounds, and includes interviews with many of those involved in planning and analyzing the samples.NASA contracted with the U.S. Geologic Survey to perform classroom and field training of the Apollo astronauts. NASA¿s Geology Group within the Manned Spacecraft Center in Houston, Texas, helped to establish the goals of sample collection, as well as the design of sample collection tools, bags, and storage containers.In this book, detailed descriptions are given on the design of the lunar sampling tools, the Modular Experiment Transporter used on Apollo 14, and the specific areas of the Lunar Rover vehicle used for the Apollo 15, 16, and 17 missions, which carried the sampling tools, bags, and other related equipment used in sample collection. The Lunar Receiving Laboratory, which was designed and built at the Manned Spacecraft Center in Texas for analysis and storage of the lunar samples returned from the Apollo lunar landing missions is also described in detail.There are also descriptions of astronaut mission training for sample collecting, with the focus on the specific portions of the mission EVAs devoted to this activity.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 124 pp. Englisch.

  • Amanda M. Evans

    Verlag: Springer New York, Springer US Mär 2017, 2017

    ISBN 10: 1493970348 ISBN 13: 9781493970346

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Taschenbuch. Zustand: Neu. Neuware -This volume presents multiple idiographic, archaeological studies of vernacular watercraft from North America and the Caribbean. Rather than attempt to synthesize all vernacular types, this volume focuses on ship construction data recovered through archaeological investigations that has been used to make inferences about culture. This collection of case studies, including many examples from cultural resource management and graduate student theses, presents a thematic exploration of cultural adaptation as expressed through ship construction.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 308 pp. Englisch.

  • Tasneem Abbasi

    Verlag: Springer New York, Springer US Mär 2017, 2017

    ISBN 10: 1493967088 ISBN 13: 9781493967087

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Taschenbuch. Zustand: Neu. Neuware -This book underscores the re-emergence of the ozone hole problem and deals with it in its current context of exacerbating global warming. It traces the history of the ozone hole from the stage of formation of the stratospheric ozone ¿layer¿, millions of years ago, into the late 20th century when the anthropogenic destruction of that ozone was discovered. The chapters are written to bring the the reader up to the present day. Factors that influence stratospheric ozone are discussed and the ways to halt ozone depletion are cataloged.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 152 pp. Englisch.

  • Oliver Schilling

    Verlag: Springer New York, Springer New York Mär 2017, 2017

    ISBN 10: 1493968491 ISBN 13: 9781493968497

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Buch. Zustand: Neu. Neuware -This volume presents detailed protocols for novel strategies and approaches to improve functional understanding of protein N- and C-terminal biology. Protein Terminal Profiling: Methods and Protocols addresses topics such as protease specificity profiling, N-terminal acetylation, assays to probe protease activity in cellular systems, protein N- and C-termini on a proteome-wide scale, and biochemical approaches to explain and examine extracellular protease activities. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 280 pp. Englisch.

  • Muhammad Naseem

    Verlag: Springer New York, Springer New York Mär 2017, 2017

    ISBN 10: 1493968297 ISBN 13: 9781493968299

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Buch. Zustand: Neu. Neuware -This volume focuses and describes tools, assays, and techniques used to enhance the understanding of the role of auxins and cytokinins. The chapters in this book cover topics such as: microbial manipulation of auxin and cytokinins in plants; interplay between auxin and cytokinin and its impact on MAPK; H2O2 production in Arabidopsis leaves; crosstalk between jasmonate and auxin in plant stress responses of roots; and high-throughput protoplast trans-activation (PTA) screening. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and comprehensive, Auxins and Cytokinins in Plant Biology: Methods and Protocols is a valuable resource to plant scientists, graduate and under graduate students in addressing their biological questions relevant to the functional implications of auxin and cytokinins.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 216 pp. Englisch.

  • Henry S. Perkins

    Verlag: Springer New York, Springer US Mär 2017, 2017

    ISBN 10: 1493968025 ISBN 13: 9781493968022

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Buch. Zustand: Neu. Neuware -Psychological, social, and spiritual care is as important as physical care at the end of life. Yet caregivers often feel ill-equipped to give that nonphysical care. This book shows how to do it. The book addresses all caregivers who attend dying patients: doctors, nurses, chaplains, clergy in the pastorate, social workers, clinical psychologists, family caregivers, and others. It covers such topics as the functional and emotional trajectories of dying; the varied approaches of patients and caregivers to end-of-life decisions; culturally based beliefs about dying; the differences between depression and grief; and people¿s views about the right time to die, the death experience itself, and the afterlife. For each topic the book introduces core concepts and summarizes recent research about them. The book presents much of its material in readable tables for easy reference; applies the material to real-life cases; lists the main ¿take home¿ points for each chapter; and gives references for additional reading. The book helps caregivers anticipate the reactions of patients and survivors to end-of-life traumas and suggests how caregivers can respond insightfully and compassionately. At the same time the book challenges caregivers to think through their own views about death and dying. This book, therefore, is a must-read for all caregivers¿professional and nonprofessional alike¿who strive to give their patients comprehensive, high-quality end-of-life care.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 504 pp. Englisch.

  • Viktor Stein

    Verlag: Springer New York, Springer New York Mär 2017, 2017

    ISBN 10: 1493969382 ISBN 13: 9781493969388

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Buch. Zustand: Neu. Neuware -This detailed book provides state-of-the-art protocols to facilitate the construction of synthetic protein switches for a variety of applications in biotechnology and basic research. Beginning with general strategies, the volume continues with coverage of peptide switches, fluorescent and bioluminescent sensors, ¿-lactamase sensors, proteolytic sensors, optogenetic switches, as well as cellular signaling switches. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 356 pp. Englisch.

  • Ddw Cornelison

    Verlag: Springer New York, Springer US Mär 2017, 2017

    ISBN 10: 149396769X ISBN 13: 9781493967698

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Buch. Zustand: Neu. Neuware -This volume provides leading-edge protocols in the study of the molecular and cellular biology of muscle stem cells. Chapters detail current and updated methods for muscle stem cell isolation, culture, molecular analysis, cellular analysis, and reintroduction in vivo as well as protocols for studying myogenic stem cells in non-mammalian model systems. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and cutting-edge, Muscle Stem Cells: Methods and Protocols aims to ensure successful results in the further study of this vital field.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 380 pp. Englisch.

  • Paul Wood

    Verlag: Springer New York, Springer New York Mär 2017, 2017

    ISBN 10: 1493969447 ISBN 13: 9781493969449

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Buch. Zustand: Neu. Neuware -This volume details methods for the analyses of specific lipid classes and lipidomics analyses of cells such as lymphocytes and oocytes. Lipidomics guides readers through chapters on direct-flow and chromatographic methods (SFC, UHPLC, HPTLC, ion-mobility); derivatization methods for lipids (amines, fatty aldehydes and ketones); TOF-SIMS imaging of lipids; and characterization of lipid transfer proteins. Additional chapters also provide an authoritative overview of lipidomics strategies and a detailed review of high-resolution mass spectrometric methods are included in this volume. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your own laboratory.Concise and easy-to-use, Lipidomics aims to ensure successful results in the further study of this vital field.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 260 pp. Englisch.

  • Takashi Tsuji

    Verlag: Springer New York, Springer New York Mär 2017, 2017

    ISBN 10: 1493969471 ISBN 13: 9781493969470

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Buch. Zustand: Neu. Neuware -This volume provides readers with a better understanding of organogenesis in developmental biology and next-generation organ regenerative therapy. This book focuses on recent studies of organ regeneration from stem cells using in vitro 3D cell culture and manipulation. The chapters cover topics such as generation of a 3D retinal tissue formation; functional salivary gland regeneration; liver regeneration using cultures liver bud; and in vivo model of small intestine. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Comprehensive and thorough, Organ Regeneration: 3D Stem Cell Culture and Manipulation is a valuable resource for scientists and researchers who are interested in this field.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 264 pp. Englisch.

  • Helen M. Mcgettrick

    Verlag: Springer New York, Springer New York Mär 2017, 2017

    ISBN 10: 1493969293 ISBN 13: 9781493969296

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Buch. Zustand: Neu. Neuware -This second edition provides updated and new chapters on T-Cell trafficking. In addition to detailed experimental procedures, the interested reader will find informative introductory chapters on the relevance of T-Cell trafficking in thymic population and maturation, traffic through secondary lymphoid organs during ¿physiological¿ resolving inflammation and during immune responses, as well as T-Cell trafficking in chronic inflammatory diseases. Importantly, chapters cover methods from in silico modeling of cellular interactions, in vitro adhesion assays, through ex vivo functional assays to integrated intravital modeling of T-Cell trafficking through organs. Written in the highly successful Methods in Molecular Biology series format, each methods chapter includes a short introduction to the topic, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and practical, T-Cell Trafficking: Methods and Protocols, Second Edition aims to be an essential point of reference for those new to the field of T-Cell trafficking, or to those looking to expand their technical capabilities.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 264 pp. Englisch.

  • G. Eric Schaller

    Verlag: Springer New York, Springer New York Mär 2017, 2017

    ISBN 10: 1493968521 ISBN 13: 9781493968527

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Buch. Zustand: Neu. Neuware -This volume provides a collection of protocols aimed toward the study of ethylene signaling in plants. Ethylene Signaling: Methods and Protocols is divided into three sections: ethylene biosynthesis, the signal transduction pathway, and the diverse ethylene responses of dicots and monocots. The chapters in section one discuss techniques for the measurement of activities related to the biosynthetic enzymes ACC synthase and ACC oxidase, the levels of ethylene synthesized by plants, and the treatment of plants with exogenous ethylene. Section two focuses on the analysis of the new membrane-associated proteins involved in the initial perception and transduction of the ethylene signal, such as ethylene receptors, CTR1, and EIN2. The third section covers assays applicable to dicots and monocots, including methods related to the roles of ethylene in germination, growth, abscission, abiotic stress, and defense. Section three also includes information on Arabidopsis mutantsand the variety of chemical inhibitors that affect ethylene responses. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Thorough and comprehensive, Ethylene Signaling: Methods and Protocols is a valuable resource for both experienced and beginner researchers with prior experience in the study of ethylene signaling and for those who are just entering this exciting research field.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 284 pp. Englisch.

  • Ben Prickril

    Verlag: Springer New York, Springer New York Mär 2017, 2017

    ISBN 10: 1493968467 ISBN 13: 9781493968466

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Buch. Zustand: Neu. Neuware -This volume provides comprehensive and detailed technical protocols on current biosensor and biodetection technologies and examples of their applications and capabilities. Chapters in Biosensors and Biodetection: Methods and Protocols, Volume 1: Optical-Based Detectors, Second Edition chapters focus on direct and indirect optical detectors including surface plasmon resonance, interferometric sensors, charge-coupled device (CCD) based detectors, spectrometry, and many other cutting-edge optical biosensors technologies. Written in the format of the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, tips on troubleshooting and avoiding known pitfalls, and step-by-step, readily reproducible laboratory protocols.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 480 pp. Englisch.

  • Tenneille E. Ludwig

    Verlag: Springer New York, Springer New York Mär 2017, 2017

    ISBN 10: 1493969196 ISBN 13: 9781493969197

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Buch. Zustand: Neu. Neuware -This volume covers protocols related to both pluripotent and somatic stem cells, including the ethical procurement of tissues and cells for the provision of ¿seed stock,¿ standardized methods for deriving hESCs and iPSCs, isolating mesenchymal stem cells, cell culture and cryopreservation, in addition to quality assurance and information management. Stem Cell Banking: Concepts and Protocols aims to contribute to the development of this field by providing information that is essential to establishing a bona fide stem cell bank. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and thorough, Stem Cell Banking: Concepts and Protocols is a valuable resource for stem cell scientists and novices to the field, and will help strengthen and maximize their use of existing and future stem cell resources.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 220 pp. Englisch.

  • Claudio Casoli

    Verlag: Springer New York, Springer New York Mär 2017, 2017

    ISBN 10: 149396870X ISBN 13: 9781493968701

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Buch. Zustand: Neu. Neuware -While HIV-1 continues to be well-researched, this detailed volume draws attention to other members of the Retrovirus family, namely the Human T-lymphotropic Viruses (HTLVs), featuring the most updated technical information about HTLV determination and the methods to investigate their interaction with the host immune system and interfering pathogens. The contents include essential aspects of epidemiology and virus transmission, novel and robust methodologies for studying the effects of trans-activating regulatory HTLVs¿ proteins, the latest techniques for genotyping and gene expression analysis, as well as cellular phenotype and dynamics. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 236 pp. Englisch.

  • Alexandra Lusser

    Verlag: Springer New York, Springer New York Mär 2017, 2017

    ISBN 10: 149396805X ISBN 13: 9781493968053

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Buch. Zustand: Neu. Neuware -This volume provides a comprehensive collection of current methods and protocols to study posttranscriptional base modifications in RNA with special focus on methylation. The protocols in this book discuss state-of-the-art methods for investigating aspects of RNA methylation on different types of RNA. The protocols cover topics such as wet-lab techniques for the detection of methylation, instructions for bioinformatics analyses of transcriptome-scale data, and protocols for the functional examination of RNA modifications and enzymes. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and thorough, RNA Methylation: Methods and Protocols is a valuable resource for biochemists and molecular biologists, from various fields, who wish to investigate different types of RNA methylations.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 316 pp. Englisch.

  • Marcos Alcocer

    Verlag: Springer New York, Springer New York Mär 2017, 2017

    ISBN 10: 1493969234 ISBN 13: 9781493969234

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Buch. Zustand: Neu. Neuware -This volume provides a collection of methodologies for basic research, clinical diagnosis, and treatment pertaining to food allergens, including food allergen production, purification, characterization, detection, quantification, and bioinformatics approaches to modern food allergen studies. The chapters in the book are divided into 4 parts: Part I discusses food allergen purification and production, and explores methods of producing recombinant food allergens in bacterial and yeast expression systems; Part II looks at allergen discovery, detection, and quantification covering 3 types of methods¿DNA-, protein-, and cell-based methods; Part III focuses on allergenic epitope mapping; and Part IV talks about future developments concentrated around new concepts of allergenicity as an outcome of protein and food matrix interactions. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists ofthe necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and comprehensive, Food Allergens: Methods and Protocols is a valuable resource for immunologists, biochemists, molecular biologists, and medical doctors and students working in the food allergy field. This book is also useful for people in the food industry, legislators, food standard agencies, allergologists, pediatricians, and clinicians in the allergic diseases and immunology fields.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 312 pp. Englisch.

  • Yuriy M. Usachev

    Verlag: Springer New York, Springer New York Mär 2017, 2017

    ISBN 10: 1493968882 ISBN 13: 9781493968886

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Buch. Zustand: Neu. Neuware -This volume describes a broad spectrum of experimental approaches for investigating structure, function, and transport of neuronal mitochondria in health and disease. Most of these approaches were only recently developed and range from electron tomography-based 3D reconstruction of mitochondrial cristae to patch clamp recording from mitochondria in intact neurons. The chapters in this book cover topics such as mitochondrial proteomics, fluorescence lifetime imaging, respirometry and mitophagy, as well as optical approaches based on the use of genetically engineered fluorescent sensors for monitoring synaptic ATP and axonal ROS generation, mitochondrial Ca2+ cycling and pH changes, and mitochondrial dynamics and axonal trafficking in live neurons. Each chapter also discusses difficulties, tips, tricks, and precautions to take. Neuromethods series style chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory.Cutting-edge and comprehensive, Techniques to Investigate Mitochondrial Function in Neurons is a valuable and useful resource for a broad range of investigators interested in the function of neuronal mitochondria in health and disease states.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 360 pp. Englisch.

  • Ping He

    Verlag: Springer US, Springer New York Mär 2017, 2017

    ISBN 10: 1493968580 ISBN 13: 9781493968589

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Buch. Zustand: Neu. Neuware -This volume covers protocols on techniques ranging from MAMP isolations from diverse microorganisms, PRR identifications from different plant species, MAMP-PRR binding, and a series of signaling responses and events revealed by various biochemical, cellular, genetic and bioinformatic tools. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and practical, Plant Pattern Recognition Receptors: Methods and Protocols aims to ensure successful results in the further study of this vital field.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 372 pp. Englisch.

  • Madeleine Ennis

    Verlag: Springer New York, Springer New York Mär 2017, 2017

    ISBN 10: 1493968416 ISBN 13: 9781493968411

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Buch. Zustand: Neu. Neuware -This book illustrates the current state-of-the-art in histamine research, with a focus on the appropriate methodologies to investigate the pharmacological properties and the therapeutic exploitation of HRs and their ligands. In addition, the range of techniques described provides an introduction to complementary cross-methodological disciplines beyond these fields. This multi-disciplinary approach is required to define the ¿decision gates¿ that determine the development of more effective and safer therapeutic options for many forms of highly prevalent and debilitating diseases, such as asthma, dementias, dermatitis, and arthritis. Written for the Methods in Pharmacology and Toxicology series, chapters concentrate on practical, hands-on protocols from experts in the techniques.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 536 pp. Englisch.

  • Zhou Songyang

    Verlag: Springer New York, Springer New York Mär 2017, 2017

    ISBN 10: 1493968912 ISBN 13: 9781493968916

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Buch. Zustand: Neu. Neuware -This third edition volume expands on the previous editions with new and improved assays that ask essential questions of telomere regulation in diverse model systems. The chapters in this book discuss genetic, proteomic, genomic, biochemical, and molecular approaches that provide insight into the complex protein interaction networks active in the telomere chromatin. This book also details information regarding telomere dynamics in response to stress or stimuli. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and thorough, Telomeres and Telomerase: Methods and Protocols, Third Edition is a valuable and informative resource for anyone who is interested in the developing field of telomeres and telomerase.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 232 pp. Englisch.

  • Fabiana Perocchi

    Verlag: Springer New York, Springer New York Mär 2017, 2017

    ISBN 10: 149396822X ISBN 13: 9781493968220

    Sprache: Englisch

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    Buch. Zustand: Neu. Neuware -This volume compiles a broad range of step-by-step protocols, complementary to the ones published in the first edition of this book, to study various aspects of mitochondrial structure and function in different model organisms, both in vitro and in vivo. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and practical, Mitochondria: Practical Protocols, Second Edition aims to be useful for beginners as well as for experienced researchers in the field.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 424 pp. Englisch.

  • Charles A. Galea

    Verlag: Springer New York, Springer New York Mär 2017, 2017

    ISBN 10: 1493968610 ISBN 13: 9781493968619

    Sprache: Englisch

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    Buch. Zustand: Neu. Neuware -Since the identification of the first matrix metalloprotease (insterstitial collagenase or MMP-1) more than 20 closely related and evolutionarily conserved vertebrate MMPs have been discovered. Chapters in this volume detail methods and protocols on recent advances in the expression and purification of MMPs, biophysical methods such as X-ray crystallography, NMR spectroscopy and small angle X-ray scattering, computational and experimental methods for determining MMP specificity, methods for detecting MMP activity in vitro and in vivo, and methods for the development and characterization of MMP-based inhibitors as potential therapeutics for the treatment of various diseases. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and practical, Matrix Metalloproteases: Methods and Protocols aims to ensure successful results in the further study of this vital field.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 328 pp. Englisch.

  • Sara Napoli

    Verlag: Springer New York, Springer New York Mär 2017, 2017

    ISBN 10: 1493967142 ISBN 13: 9781493967148

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Buch. Zustand: Neu. Neuware -This volume is divided in four sections; covering genome wide approaches, techniques for characterize of paRNA structural features are described, selecting pa-RNA, and paRNA therapeutic potential. Chapters describe how siRNAsdirected against paRNAs can be applied in vivo to modulate transcription of important genes controlled by paRNAs. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and cutting-edge, Promoter Associated RNA: Methods and Protocols aims to demonstrate paRNAs as new class of regulatory molecules, to further investigate and value as tools for fine transcriptional tuning.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 300 pp. Englisch.

  • David T. Stuart

    Verlag: Springer New York, Springer US Mär 2017, 2017

    ISBN 10: 1493963384 ISBN 13: 9781493963386

    Sprache: Englisch

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    Buch. Zustand: Neu. Neuware -This updated book includes meiosis methods ranging from classical genetic approaches with budding yeast to high resolution microscopy and computational methods for the analysis of recombination and modeling gene expression networks. Cutting-edge procedures for the analysis of double strand breaks at single nucleotide resolution, analysis of translation by ribosome profiling, the use of fluorescent markers to analyze recombination, and strategies for the use of conditional expression to study chromatin protein dynamics are detailed. Advanced cytology methods for live and fixed cell microscopy and image analysis for yeast, drosophila, and mouse are also included. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 348 pp. Englisch.

  • Thomas Tiller

    Verlag: Springer New York, Springer New York Mär 2017, 2017

    ISBN 10: 1493968556 ISBN 13: 9781493968558

    Sprache: Englisch

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    Buch. Zustand: Neu. Neuware -This detailed volume presents a set of protocols useful for researchers in the field of recombinant immunoglobulin and alternative scaffold engineering, aptamer development, and generation of molecularly imprinted polymers (MIPs). Part I includes methods that deal with amino-acid based synthetic antibodies. Brief protocols about the generation of antibody libraries are detailed, as well as techniques for antibody selection, characterization, and validation. This section is completed by a brief description of a bioinformatics platform that supports antibody engineering during research and development. Part II contains basic procedures about the selection and characterization of aptamer molecules, and Part III describes fundamental processes of MIP generation and application. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 436 pp. Englisch.

  • Joel Michael

    Verlag: Springer US, Springer New York Mär 2017, 2017

    ISBN 10: 1493969072 ISBN 13: 9781493969074

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Buch. Zustand: Neu. Neuware -This book offers physiology teachers a new approach to teaching their subject that will lead to increased student understanding and retention of the most important ideas. By integrating the core concepts of physiology into individual courses and across the entire curriculum, it provides students with tools that will help them learn more easily and fully understand the physiology content they are asked to learn. The authors present examples of how the core concepts can be used to teach individual topics, design learning resources, assess student understanding, and structure a physiology curriculum.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 172 pp. Englisch.

  • Michael L. Dustin

    Verlag: Springer New York, Springer New York Mär 2017, 2017

    ISBN 10: 1493968793 ISBN 13: 9781493968794

    Sprache: Englisch

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    Buch. Zustand: Neu. Neuware -This volume provides all the essential protocols that are currently used to study the immune synapse. Chapters in The Immune Synapse: Methods and Protocols cover methods for the study of the dynamics of immune synapse assembly, traffic at the immune synapse, new high resolution imaging, biophysical and computational methods for the study of the immune synapse, effector immune synapses, B cell, NK and mast cell immune synapses, and immune interactions in vivo. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and practical, The Immune Synapse: Methods and Protocols will be of interest to immunologists and, at a more general level, to cell biologists, biophysicists and computational biologists.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 604 pp. Englisch.

  • Avraham Rasooly

    Verlag: Springer New York, Springer New York Mär 2017, 2017

    ISBN 10: 1493969102 ISBN 13: 9781493969104

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Buch. Zustand: Neu. Neuware -This volume provides comprehensive and detailed technical protocols on current biosensor and biodetection technologies and examples of their applications and capabilities. Chapters in Biosensors and Biodetection: Methods and Protocols Volume 2, Electrochemical, Bioelectronic, Piezoelectric, Cellular and Molecular Biosensors, Second Edition focus on electrochemical biosensors including amperometric, impedance and voltammetric sensors, bioelectronic, piezoelectric, cellular, and molecular biosensors. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, tips on troubleshooting and avoiding known pitfalls, and step-by-step, readily reproducible laboratory protocols.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 596 pp. Englisch.

  • Kewal K. Jain

    Verlag: Springer New York, Springer US Mär 2017, 2017

    ISBN 10: 149396965X ISBN 13: 9781493969654

    Sprache: Englisch

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    Buch. Zustand: Neu. Neuware -Nanomedicine is defined as the application of nanobiotechnology in clinical medicine, which is currently being used to research the pathomechanism of disease, refine molecular diagnostics, and aid in the discovery, development, and delivery of drugs. InThe Handbook of Nanomedicine, Third Edition, Prof. Kewal K. Jain updates, reorganizes, and replaces information in the comprehensive second edition in order to capture the most recent advances in this dynamic field. Important components of nanomedicine such as drug delivery via nanobiotechnology and nanopharmaceuticals as well as nanooncology, where the greatest number of advances are occurring, are covered extensively. As this text is aimed at nonmedical scientists, pharmaceutical personnel, as well as physicians, descriptions of the technology involved and other medical terminology are kept as clear and simple as possible.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 680 pp. Englisch.