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  • Juli Peretó

    Verlag: Springer Netherlands, Springer Netherlands Sep 2014, 2014

    ISBN 10: 9401793816 ISBN 13: 9789401793810

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Taschenbuch. Zustand: Neu. Neuware -Synthetic Biology (SB) is a revolutionary discipline with a vast range of practical applications, but is SB research really based on engineering principles Does it contributing to the artificial synthesis of life or does it utilise approaches sufficiently advanced to fall outside the scope of biotechnology or metabolic engineering This volume reviews the development of SB and includes the major milestones of the discipline, the ¿top-down¿ and ¿bottom-up¿ approaches towards the construction of an artificial cell and the development of the ¿iGEM¿ competition. We conclude that SB is an emerging field with extraordinary technological potential, but that most research projects actually are an extension of metabolic engineering since the complexity of living organisms, their tight dependence on evolution and our limited knowledge of the interactions between the molecules, actually make life difficult to engineer.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 92 pp. Englisch.

  • H. Wittenberg

    Verlag: Springer Netherlands, Springer Netherlands Sep 2014, 2014

    ISBN 10: 9400790600 ISBN 13: 9789400790605

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Taschenbuch. Zustand: Neu. Neuware -Knowledge is not merely everything we have come to know, but also ideas we have pondered long enough to know in which way they are related, and 1 how these ideas can be put to practical use. Modern aviation has been made possible as a result of much scienti c - search. However, the very rst useful results of this research became ava- able a considerable length of time after the aviation pioneers had made their rst ights. Apparently, researchers were not able to nd an adequate exp- nation for the occurrence of lift until the beginning of the 21st century. Also, for the fundamentals of stability and control, there was no theory available that the pioneers could rely on. Only after the rst motorized ights had been successfully made did researchers become more interested in the science of aviation, which from then on began to take shape. In modern day life, many millions of passengers are transported every year by air. People in the western societies take to the skies, on average, severaltimes a year. Especially in areas surrounding busy airports, travel by plane has been on the rise since the end of the Second World War. Despite becoming familiar with the sight of a jumbo jet commencing its ight once or twice a day, many nd it astonishing that such a colossus with a mass of several hundred thousands of kilograms can actually lift off from the ground.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 552 pp. Englisch.

  • Marina Fischer-Kowalski

    Verlag: Springer Netherlands, Springer Netherlands Sep 2014, 2014

    ISBN 10: 9401786771 ISBN 13: 9789401786775

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Buch. Zustand: Neu. Neuware -Arising from a scientific conference marking the 100th anniversary of her birth, this book honors the life and work of the social scientist and diplomat Ester Boserup, who blazed new trails in her interdisciplinary approach to development and sustainability.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 296 pp. Englisch.

  • Michel Bourdeau

    Verlag: Springer Netherlands, Springer Netherlands Sep 2014, 2014

    ISBN 10: 940179216X ISBN 13: 9789401792165

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Buch. Zustand: Neu. Neuware -Ranging from Alan Turing¿s seminal 1936 paper to the latest work on Kolmogorov complexity and linear logic, this comprehensive new work clarifies the relationship between computability on the one hand and constructivity on the other. The authors argue that even though constructivists have largely shed Brouwer¿s solipsistic attitude to logic, there remain points of disagreement to this day.Focusing on the growing pains computability experienced as it was forced to address the demands of rapidly expanding applications, the content maps the developments following Turing¿s ground-breaking linkage of computation and the machine, the resulting birth of complexity theory, the innovations of Kolmogorov complexity and resolving the dissonances between proof theoretical semantics and canonical proof feasibility. Finally, it explores one of the most fundamental questions concerning the interface between constructivity and computability: whether the theory of recursive functions is needed for a rigorous development of constructive mathematics.This volume contributes to the unity of science by overcoming disunities rather than offering an overarching framework. It posits that computability¿s adoption of a classical, ontological point of view kept these imperatives separated. In studying the relationship between the two, it is a vital step forward in overcoming the disagreements and misunderstandings which stand in the way of a unifying view of logic.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 228 pp. Englisch.

  • Mariana G. Hewson

    Verlag: Springer Netherlands, Springer Netherlands Sep 2014, 2014

    ISBN 10: 9401792992 ISBN 13: 9789401792998

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Buch. Zustand: Neu. Neuware -The focus of the book is on different ways of knowing: the western scientific way (reductionist, dualistic and materialist) versus the indigenous approach (holistic, non-dualistic, and spiritual). It discusses both science and medicine in the context of the challenges experienced in introducing science and medicine into Africa through imperialism, colonization, and globalization. It looks at selected indigenous African paradigms, the dominant western paradigms, and the practitioners that represent these practices. The book deals with questions concerning compatibility and incompatibility of different ways of knowing and delves into epistemological stances, and the assumptions underlying these epistemologies. The volume investigates whether, and how a person can accommodate different epistemologies, and the nature of such accommodations.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 172 pp. Englisch.

  • Marcel Lesieur

    Verlag: Springer Netherlands, Springer Netherlands Sep 2014, 2014

    ISBN 10: 9401781303 ISBN 13: 9789401781305

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Taschenbuch. Zustand: Neu. Neuware -Turbulence is a dangerous topic which is often at the origin of serious ghts in the scienti c meetings devoted to it since it represents extremely di erent points of view, all of which have in common their complexity, as well as an inability to solve the problem. It is even di cult to agree on what exactly is the problem to be solved. Extremely schematically, two opposing points of view had been adv- ated during these last thirty years: the rst one was ¿statistical¿, and tried to model the evolution of averaged quantities of the ow. This community, which had followed the glorious trail of Taylor and Kolmogorov, believed in the phenomenology of cascades, and strongly disputed the possibility of any coherence or order associated to turbulence. On the other bank of the river standed the ¿coherence among chaos¿ community, which considered turbulence from a purely deterministic point of view, by studying either the behaviour of dynamical systems, or the stability of ows in various situations. To this community were also associated the experimentalists and computer simulators who sought to identify coherent vortices in ows. Situation is more complex now, and the existence of these two camps is less clear. In fact a third point of view pushed by people from the physics community has emerged, with the concepts of renormalization group theory, multifractality, mixing, and Lagrangian approaches.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 604 pp. Englisch.

  • Ove Stephansson

    Verlag: Springer Netherlands, Springer Netherlands Sep 2014, 2014

    ISBN 10: 9400795157 ISBN 13: 9789400795150

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Taschenbuch. Zustand: Neu. Neuware -Stress Field of the Earth¿s Crust is based on lecture notes prepared for a course offered to graduate students in the Earth sciences and engineering at University of Potsdam. In my opinion, it will undoubtedly also become a standard reference book on the desk of most scientists working with rocks, such as geophysicists, structural geologists, rock mechanics experts, as well as geotechnical and petroleum en- neers. That is because this book is concerned with what is probably the most pe- liar characteristic of rock ¿ its initial stress condition. Rock is always under a natural state of stress, primarily a result of the gravitational and tectonic forces to which it is subjected. Crustal stresses can vary regionally and locally and can reach in places considerable magnitudes, leading to natural or man-made mechanical failure. P- existing stress distinguishes rock from most other materials and is at the core of the discipline of ¿Rock Mechanics¿, which has been developed over the last century. Knowledge of rock stress is fundamental to understanding faulting mechanisms and earthquake triggering, to designing stable underground caverns and prod- tive oil fields, and to improving mining methods and geothermal energy extraction, among others. Several books have been written on the subject, but none has atte- ted to be as all-encompassing as the one by Zang and Stephansson.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 344 pp. Englisch.

  • Arnold L. Demain

    Verlag: Springer Netherlands, Springer Netherlands Sep 2014, 2014

    ISBN 10: 9401783209 ISBN 13: 9789401783200

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Taschenbuch. Zustand: Neu. Neuware -Protein hydrolysates, otherwise commonly known as peptones or peptides, are used in a wide variety of products in fermentation and biotechnology industries. The term ¿peptone¿ was first introduced in 1880 by Nagelli for growing bacterial cultures. However, later it was discovered that peptones derived from the partial digestion of proteins would furnish organic nitrogen in readily available form. Ever since, p- tones, which are commonly known as protein hydrolysates, have been used not only for growth of microbial cultures, but also as nitrogen source in commercial fermen- tions using animal cells and recombinant microorganisms for the production of value added products such as therapeutic proteins, hormones, vaccines, etc. Today, the characterization, screening and manufacturing of protein hyd- lysates has become more sophisticated, with the introduction of reliable analytical instrumentation, high throughput screening techniques coupled with statistical design approaches, novel enzymes and efficient downstream processing equipment. This has enabled the introduction of custom-built products for specialized appli- tions in diverse fields of fermentation and biotechnology, such as the following. 1. Protein hydrolysates are used as much more than a simple nitrogen source. For example, the productivities of several therapeutic drugs made by animal cells and recombinant microorganisms have been markedly increased by use of p- tein hydrolysates. This is extremely important when capacities are limited. 2. Protein hydrolysates are employed in the manufacturing of vaccines by ferm- tation processes and also used as vaccine stabilizers.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 244 pp. Englisch.

  • Carlos María Romeo Casabona

    Verlag: Springer Netherlands, Springer Netherlands Sep 2014, 2014

    ISBN 10: 9401791953 ISBN 13: 9789401791953

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Buch. Zustand: Neu. Neuware -Since 2010, the Inter-university chair in law and the Human Genome has been involved in an EU 7th Framework Programme funded Project called Sybhel, leading work package 5. The aim of this work package was to face the issues related to synthetic biology and intellectual property rights. In these years, the Chair organized two international workshops devoted to this topic, collecting a number of high level unpublished papers redacted by some of the most prominent experts in this field worldwide, including Stephen Maurer, Joachim Henkel, Ingrid Schneider, etc. We consider that it would be extremely interesting to have them all gathered in a unique contributed volume, which would be the first book exclusively dedicated to analyze the implications that Synbio may involve in what refers to the currently existing intellectual property rights system.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 240 pp. Englisch.

  • Ellen Karoline Henriksen

    Verlag: Springer Netherlands, Springer Netherlands Sep 2014, 2014

    ISBN 10: 9400777922 ISBN 13: 9789400777927

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Buch. Zustand: Neu. Neuware -Drawing on data generated by the EU¿s Interests and Recruitment in Science (IRIS) project, this volume examines the issue of young people¿s participation in science, technology, engineering and mathematics education. With an especial focus on female participation, the chapters offer analysis deploying varied theoretical frameworks, including sociology, social psychology and gender studies. The material also includes reviews of relevant research in science education and summaries of empirical data concerning student choices in STEM disciplines in five European countries.Featuring both quantitative and qualitative analyses, the book makes a substantial contribution to the developing theoretical agenda in STEM education. It augments available empirical data and identifies strategies in policy-making that could lead to improved participation¿and gender balance¿in STEM disciplines. The majority of the chapter authors are IRIS project members, with additional chapters written by specially invited contributors. The book provides researchers and policy makers alike with a comprehensive and authoritative exploration of the core issues in STEM educational participation.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 428 pp. Englisch.

  • John Allen Tucker

    Verlag: Springer Netherlands, Springer Netherlands Sep 2014, 2014

    ISBN 10: 9048129206 ISBN 13: 9789048129201

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Buch. Zustand: Neu. Neuware -The Dao Companion to Japanese Confucian Philosophy will be part of the handbook series Dao Companion to Chinese Philosophy, published by Springer. This series is being edited by Professor Huang Yong, Professor of Philosophy at Kutztown University and Editor of Dao: A Journal of Comparative Philosophy. This volume includes original essays by scholars from the U.S., Europe, Japan, and China, discussing important philosophical writings by Japanese Confucian philosophers. The main focus, historically, will be the early-modern period (1600-1868), when much original Confucian philosophizing occurred, and Confucianism in modern Japan.The Dao Companion to Japanese Confucian Philosophy makes a significant contribution to the Dao handbook series, and equally to the field of Japanese philosophy. This new volume including original philosophical studies will be a major contribution to the study of Confucianism generally and Japanese philosophy in particular.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 444 pp. Englisch.

  • Elin McCready

    Verlag: Springer Netherlands, Springer Netherlands Sep 2014, 2014

    ISBN 10: 940178812X ISBN 13: 9789401788120

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Buch. Zustand: Neu. Neuware -This volume presents an exploration of a wide variety of new formal methods from computer science, biology and economics that have been applied to problems in semantics and pragmatics in recent years. Many of the contributions included focus on data from East Asian languages, particularly Japanese and Korean. The collection reflects on a range of new empirical issues that have arisen, including issues related to preference, evidentiality and attention. Separated into several sections, the book presents discussions on: information structure, speech acts and decisions, philosophical themes in semantics and new formal approaches to semantic and pragmatic theory. Its overarching theme is the relation between different kinds of content, from a variety of perspectives. The discussions presented are both theoretically innovative and empirically motivated.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 388 pp. Englisch.

  • Sukhbir Sandhu

    Verlag: Springer Netherlands, Springer Netherlands Sep 2014, 2014

    ISBN 10: 9401790078 ISBN 13: 9789401790079

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Buch. Zustand: Neu. Neuware -The book takes a holistic approach to sustainability. Acknowledging the Brundtland definition, that sustainable development meets the needs of the present without compromising the ability of future generations to meet their own needs, the book is specifically concerned with the ethics of contemporary social and environmental sustainability activity and thinking. It is concerned with the role of institutions¿both local and global in achieving sustainability initiatives. All twelve chapters extend sustainability¿conceptually, empirically and theoretically, and in doing so provide insights into linking local and global sustainability. The book refocuses sustainability as a series of interwoven and dynamic relationships, backed by just ethical decision-making, which begin locally, and reach out to impact the global level.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 244 pp. Englisch.

  • Marja Elsinga

    Verlag: Springer Netherlands, Springer Netherlands Sep 2014, 2014

    ISBN 10: 9400795726 ISBN 13: 9789400795723

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Taschenbuch. Zustand: Neu. Neuware -Across the EU, populations are shrinking and ageing. An increasing burden is being placed on a smaller working population to generate the taxes required for pensions and care costs. Welfare states are weakening in many countries and across Europe, households are being increasingly expected to plan for their retirement and future care needs within this risky environment. At the same time, the proportion of people buying their own home in most countries has risen, so that some two-thirds of European households now own their homes. Housing equity now considerably exceeds total European GDP.This book discusses questions like: to what extent might home ownership provide a potential cure for some of the consequences of ageing populations by realizing housing equity in order to meet the consumption needs of older people What does this mean for patterns of inheritance and longer-term inequalities across Europe And to what extent are governments banking on their citizens utilising their housing wealth now and in the future Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 180 pp. Englisch.

  • Yiannos Manoli

    Verlag: Springer Netherlands, Springer Netherlands Sep 2014, 2014

    ISBN 10: 9401792712 ISBN 13: 9789401792714

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Buch. Zustand: Neu. Neuware -Chip-integrated power management solutions are a must for ultra-low power systems. This enables not only the optimization of innovative sensor applications. It is also essential for integration and miniaturization of energy harvesting supply strategies of portable and autonomous monitoring systems.The book particularly addresses interfaces for energy harvesting, which are the key element to connect micro transducers to energy storage elements. Main features of the book are: A comprehensive technology and application review, basics on transducer mechanics, fundamental circuit and control design, prototyping and testing, up to sensor system supply and applications. Novel interfacing concepts - including active rectifiers, MPPT methods for efficient tracking of DC as well as AC sources, and a fully-integrated charge pump for efficient maximum AC power tracking at sub-100µW ultra-low power levels. The chips achieve one of widest presented operational voltage range in standard CMOS technology: 0.44V to over 4.1V. Two special chapters on analog circuit design ¿ it studies benefits and obstacles on implemented chip prototypes with three goals: ultra- low power, wide supply voltage range, and integration with standard technologies. Alternative design approaches are pursued using bulk-input transistor stages in forward-bias operation for amplifiers, modulators, and references. Comprehensive Appendix ¿ with additional fundamental analysis, design and scaling guidelines, circuit implementation tables and dimensions, schematics, source code listings, bill of material, etc.The discussed prototypes and given design guidelines are tested with real vibration transducer devices. The intended readership is graduate students in advanced courses, academics and lecturers, R&D engineers.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 324 pp. Englisch.

  • Neal S. Gupta

    Verlag: Springer Netherlands, Springer Netherlands Sep 2014, 2014

    ISBN 10: 9400779356 ISBN 13: 9789400779358

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Buch. Zustand: Neu. Neuware -This book provides an overview, research compendium and an introduction to the science of molecular paleontology, including literature overview for non-geochemists. Analytical methods employed are included as a part of each chapter that underpin this branch of paleontology and indeed geochemistry. The primary usefulness of this volume is for organic geochemists, molecular palaeontologists, and molecular archeologists. Researchers, graduate students and academics interested in astrobiology from a paleontological perspective may also find this to be valuable.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 200 pp. Englisch.

  • Jari Nurmi

    Verlag: Springer Netherlands, Springer Netherlands Sep 2014, 2014

    ISBN 10: 9400718292 ISBN 13: 9789400718296

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Buch. Zustand: Neu. Neuware -This book covers multi-band Galileo receivers (especially E1-E5 bands of Galileo) and addresses all receiver building blocks, from the antenna and front end, through details of the baseband receiver processing blocks, up to the navigation processing, including the Galileo message structure and Position, Velocity, Time (PVT) computation. Moreover, hybridization solutions with communications systems for improved localization are discussed and an open-source GNSS receiver platform (available for download) developed at Tampere University of Technology (TUT) is addressed in detail.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 420 pp. Englisch.

  • Jose G Pereira

    Verlag: Springer Netherlands, Springer Netherlands Sep 2014, 2014

    ISBN 10: 9400796722 ISBN 13: 9789400796720

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Taschenbuch. Zustand: Neu. Neuware -Teleparallel Gravity (TG) is an alternative theory for gravitation, which is equivalent to General Relativity (GR). However, it is conceptually different. For example in GR geometry replaces the concept of force, and the trajectories are determined by geodesics. TG attributes gravitation to torsion, which accounts for gravitation by acting as a force.TG has already solved some old problems of gravitation (like the energy-momentum density of the gravitational field). The interest in TG has grown in the last few years.The book here proposed will be the first one dedicated exclusively to TG, and will include the foundations of the theory, as well as applications to specific problems to illustrate how the theory works.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 228 pp. Englisch.

  • Øyvind Bjøntegaard

    Verlag: Springer Netherlands, Springer Netherlands Sep 2014, 2014

    ISBN 10: 9401792658 ISBN 13: 9789401792653

    Sprache: Englisch

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    Buch. Zustand: Neu. Neuware -This report presents the Round-Robin (RR) program and test results including a statistical evaluation of the RILEM TC195-DTD committee named ¿Recommendation for test methods for autogenous deformation (AD) and thermal dilation (TD) of early age concrete¿. The task of the committee was to investigate the linear test set-up for AD and TD measurements (Dilation Rigs) in the period from setting to the end of the hardening phase some weeks after. These are the stress-inducing deformations in a hardening concrete structure subjected to restraint conditions.The main task was to carry out an RR program on testing of AD of one concrete at 20 °C isothermal conditions in Dilation Rigs. The concrete part materials were distributed to 10 laboratories (Canada, Denmark, France, Germany, Japan, The Netherlands, Norway, Sweden and USA), andin total 30 tests on AD were carried out. Some supporting tests were also performed, as well as a smaller RR on cement paste. The committee has worked out a test procedure recommendation which is reported separately and submitted acceptance as a RILEM method.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 112 pp. Englisch.

  • M. A. Hayat

    Verlag: Springer Netherlands, Springer Netherlands Sep 2014, 2014

    ISBN 10: 9401793247 ISBN 13: 9789401793247

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Buch. Zustand: Neu. Neuware -This third volume in the series Tumor Dormancy, Quiescence, and Senescence discusses the role of tumor dormancy and senescence in a number of diseases, including breast cancer, ovarian cancer and leukemia. The contents are organized under five subheadings: General Applications, Role in Breast Cancer, Role in Ovarian Cancer, Role in Leukemia and Role in Cardiovascular Disease. The first section includes basic information on the definition of dormancy, how cells become senescent and what they do, along with an appraisal of the current state of research on dormancy. Section Two explores dormancy in breast cancer, including the progression of hormone-dependent mammary tumors after dormancy. Section Three details the resistance of Type II ovarian tumors, in which the resistant tumor cell population persists after chemotherapy in a state of dormancy, with recurrent tumors arising upon transformation of such dormant cells back to malignant growth. This section explains how lineage, histological subtypes and grade influence the differential response of ovarian cancer resistance to platinum drugs. The fourth section explores leukemia, discussing regulation of the promyelocytic leukemia protein and its role in premature senescence. The final section explores the role of senescence and autophagy in age-related cardiovascular diseases and the observation that autophagy seems to retard cardiac senescence. Like the two preceding volumes in the series, Volume 3 stands out for its comprehensive approach, its roster of some 26 expert contributors representing seven different countries and its up-to-date review of leading-edge technology and methods.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 172 pp. Englisch.

  • Meral Özgüç

    Verlag: Springer Netherlands, Springer Netherlands Sep 2014, 2014

    ISBN 10: 9401792135 ISBN 13: 9789401792134

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Buch. Zustand: Neu. Neuware -This book focuses on predictive, preventative and personalized medicine (PPPM) and how it is related to the healthcare of rare diseases. Readers will discover how advanced rare diseases healthcare provides an excellent ¿proof-of-principles¿ for the personalisation of healthcare systems on a global scale. Chapters look at national plans for rare disease, at biobanking, gene identification, rare cancers, virus gene therapy , induced pluripotency for cell therapy amongst other topics. There is a chapter dedicated to personalized medicine for hereditary deafness and another exploring the complexity of genotype-phenotype correlations. Specific diseases such as Fabry's, Gauchers and mitochondrial cytopathies are highlighted and we look at enzyme replacement therapy in lysosomal storage diseases. This work is part of a series, produced with the involvement of the European Association for Predictive, Preventive and Personalised Medicine. The series focusses on the concept of an integrative medical approach by PPPM. This volume is dedicated to all aspects related to the prediction, prevention and personalised treatments of rare diseases, and in doing so it explores developments relevant to all medical branches. The authors cover ethical considerations, the creation of a robust platform for professional communication, synergies with patient organisations, ¿doctor-patient¿ collaboration and a new philosophy of integrative medicine by PPPM. This volume serves as a reference source for scientific and medical centres in the field and can be used both at medical curricula and graduate level in the life sciences. Those who place a special emphasis on healthcare promotion and innovations intended to combat rare diseases, save the affected lives and enhance life quality will all find this book of great value.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 228 pp. Englisch.

  • Gulzhian I. Dzhardimalieva

    Verlag: Springer Netherlands, Springer Netherlands Sep 2014, 2014

    ISBN 10: 9048125642 ISBN 13: 9789048125647

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Buch. Zustand: Neu. Neuware -The book is devoted to novel nanostructured materials and nanotechnology. A comprehensive analysis of the condensing methods of preparation of novel nanostructured materials is given. The methodology of power-consuming preparation of nanostructured materials is discussed, including thermolysis, photo- and radiolytic, electrochemical and mechanochemical methods. The peculiarities of chemical transformations in organic and inorganic matrices are compared. Special attention is given to kinetics and mechanism of the formation of nanocomposites. The structure and properties of such nanostructured materialsare analysed.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 480 pp. Englisch.

  • Yu Mei

    Verlag: Springer Netherlands, Springer Netherlands Sep 2014, 2014

    ISBN 10: 9401793727 ISBN 13: 9789401793728

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Buch. Zustand: Neu. Neuware -The functional characterization of a key enzyme in the phosphatidylinositol (PI) signaling pathway in the model plant Arabidopsis thaliana is the focus of the research summarised in this thesis. Moreover, a particular focus is the exploration of the biological functions of Arabidopsis phophatidylinositol monophosphate 5-kinase 2 (PIP5K2) which catalyzes the synthesis of phophatidylinositol (4,5) bisphosphate, the precursor of two important second messengers (inositol 1,4,5-trisphosphate and diacylglycerol). Through molecular and genetic approaches, the author isolated and characterized the expression pattern, physiological functions and the underlying mechanism of Arabidopsis PIP5K2. It is found that PIP5K2 is involved in regulating lateral root formation and root gravity response through modulating auxin accumulation and polar auxin transport and also plays a critical role in salt tolerance. These findings shed new light on the crosstalk between PI signaling and auxin response, both of which have crucial regulatory roles in plant development.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 100 pp. Englisch.

  • A. Stewart Truswell

    Verlag: Springer Netherlands, Springer Netherlands Sep 2014, 2014

    ISBN 10: 9400799772 ISBN 13: 9789400799776

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Taschenbuch. Zustand: Neu. Neuware -¿Only once in a great while does a book come along that really does the job in addressing a major medical issue. When this happens, all can be joyful¿ Readers will find ALL their favorite dietary puzzlements dealt with¿ With consummate scholarship, clarity and brevity, Truswell sifts out the chaff and identifies the critical questions, the responsible investigators, and the key studies.¿So says Emeritus Professor Henry Blackburn from the University of Minnesota in the foreword to this remarkable concise book on the history of research on diet and heart disease. This was a theme of scientific, medical and public interest in the 20th Century, a century marked by the rise and fall of coronary heart disease as the major cause of death in the first world, followed by the rise of this cause of death in the developing world.There is obviously much to learn, and this book is an excellent starting point, tracing dietary factors and their role in heart disease one by one: fats, sugar, salt, alcohol, coffee, trans-fats, etc. Without an understanding of the role of diet and the changes that have been seen in the North American and NW European diet, the story of the decline in the heart disease death rate may have been very different.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 244 pp. Englisch.

  • David Jou

    Verlag: Springer Netherlands, Springer Netherlands Sep 2014, 2014

    ISBN 10: 9400790236 ISBN 13: 9789400790230

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Erstausgabe

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    Taschenbuch. Zustand: Neu. Neuware -This is the second edition of the book ¿Thermodynamics of Fluids under Flow,¿ which was published in 2000 and has now been corrected, expanded and updated. This is a companion book to our other title Extended irreversible thermodynamics (D. Jou, J. Casas-Vázquez and G. Lebon, Springer, 4th edition 2010), and of the textbook Understanding non-equilibrium thermodynamics (G. Lebon, D. Jou and J. Casas-Vázquez, Springer, 2008. The present book is more specialized than its counterpart, as it focuses its attention on the non-equilibrium thermodynamics of flowing fluids, incorporating non-trivial thermodynamic contributions of the flow, going beyond local equilibrium theories, i.e., including the effects of internal variables and of external forcing due to the flow. Whereas the book's first edition was much more focused on polymer solutions, with brief glimpses into ideal and real gases, the present edition covers a much wider variety of systems, such as: diluted and concentrated polymer solutions, polymer blends, laminar and turbulent superfluids, phonon hydrodynamics and heat transport in nanosystems,nuclear collisions, far-from-equilibrium ideal gases, and molecular solutions. It also deals with a variety of situations, emphasizing the non-equilibrium flow contribution: temperature and entropy in flowing ideal gases, shear-induced effects on phase transitions in real gases and on polymer solutions, stress-induced migration and its application to flow chromatography, Taylor dispersion, anomalous diffusion in flowing systems, the influence of the flow on chemical reactions, and polymer degradation. The new edition is not only broader in scope, but more educational in character, and with more emphasis on applications, in keeping with our times. It provides many examples of how a deeper theoretical understanding may bring new and more efficient applications, forging links between theoretical progress and practical aims. Thisupdated version expands on the trusted content of its predecessor, making it more interesting and useful for a larger audience.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 320 pp. Englisch.

  • Zoubeida R. Dagher

    Verlag: Springer Netherlands, Springer Netherlands Sep 2014, 2014

    ISBN 10: 9401790566 ISBN 13: 9789401790567

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Buch. Zustand: Neu. Neuware -Prompted by the ongoing debate among science educators over ¿nature of science¿, and its importance in school and university curricula, this book is a clarion call for a broad re-conceptualizing of nature of science in science education. The authors draw on the ¿family resemblance¿ approach popularized by Wittgenstein, defining science as a cognitive-epistemic and social-institutional system whose heterogeneous characteristics and influences should be more thoroughly reflected in science education. They seek wherever possible to clarify their developing thesis with visual tools that illustrate how their ideas can be practically applied in science education.The volume¿s holistic representation of science, which includes the aims and values, knowledge, practices, techniques, and methodological rules (as well as science¿s social and institutional contexts), mirrors its core aim to synthesize perspectives from the fields of philosophy of science and science education. The authorsbelieve that this more integrated conception of nature of science in science education is both innovative and beneficial. They discuss in detail the implications for curriculum content, pedagogy, and learning outcomes, deploy numerous real-life examples, and detail the links between their ideas and curriculum policy more generally.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 212 pp. Englisch.

  • Wolff-Michael Roth

    Verlag: Springer Netherlands, Springer Netherlands Sep 2014, 2014

    ISBN 10: 9400770081 ISBN 13: 9789400770089

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Buch. Zustand: Neu. Neuware -This book deals with uncertainty and graphing in scientific discovery work from a social practice perspective. It is based on a 5-year ethnographic study in an advanced experimental biology laboratory. The book shows how, in discovery work where scientists do not initially know what to make of graphs, there is a great deal of uncertainty and scientists struggle in trying to make sense of what to make of graphs. Contrary to the belief that scientists have no problem ¿interpreting¿ graphs, the chapters in this book make clear that uncertainty about their research object is tied to uncertainty of the graphs. It may take scientists several years of struggle in their workplace before they find out just what their graphs are evidence of. Graphs turn out to stand to the entire research in a part/whole relation, where scientists not only need to be highly familiar with the context from which their data are extracted but also with the entire process by means of which the natural world comes to be transformed and represented in the graph. This has considerable implications for science, technology, engineering, and mathematics education at the secondary and tertiary level, as well as in vocational training. This book discusses and elaborates these implications.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 472 pp. Englisch.

  • Ulrich Teichler

    Verlag: Springer Netherlands, Springer Netherlands Sep 2014, 2014

    ISBN 10: 9400794983 ISBN 13: 9789400794986

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Taschenbuch. Zustand: Neu. Neuware -This book is the first of several with the results of a collaborative European project supported by the European Science Foundation on changes in the academic profession in Europe (EUROAC). It provides a short description of the ESF EUROHESC programme and the particular forms of international collaborative research projects which are funded under the umbrella of this programme. It then outlines the EUROAC project. This project has chosen three foci (governance, professionalisation, academic careers) to analyse changes in the work of the academic profession. The first results in the form of in-depth literature reviews constitute the content of the book. These eight literature reviews about the state of the art of existing research feature the various dimensions of the overall theme. A particular emphasis is put on factors leading to changes in the work tasks of the academic profession in Europe and how the academic profession is coping with these new challenges.Thus, the book provides a state of the art account of existing research about the following themes: main results of previous studies on the academic profession; the academic profession and their interaction with new higher education professionals; professional identities in higher education; extending work tasks: civic mission and sustainable development; academic careers in academic markets; the changing role of academics in the face of rising managerialism; the influence of quality assurance, governance, and relevance on the satisfaction of the academic profession.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 220 pp. Englisch.

  • Ortrun Zuber-Skerritt

    Verlag: Springer Netherlands, Springer Netherlands Sep 2014, 2014

    ISBN 10: 9400796110 ISBN 13: 9789400796119

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Taschenbuch. Zustand: Neu. Neuware -Action leadership is a creative, innovative, collaborative and self-developed way to lead. It eschews the hierarchical structure usually associated with leadership and is based instead on the democratic values of freedom, equality, inclusion and self-realization. It take responsibility for, not control over, people through networking and orchestrating human energy towards a holistic outcome that benefits the common interest. Action leaders are passionate people who abide by the motto that ¿Learning does not mean to fill a barrel but rather to ignite a flame¿ in others. And in this time of rapid economic, political, technological, social and ecological changes, action leadership and action leaders are precisely what¿s needed to improve how people and organizations engage constructively to address the myriad complex issues challenging society at all levels.Action Leadership: Towards a Participatory Paradigm explains and illustrates how action leadership can be developed through participatory action learning and action research (PALAR). It addresses real-life issues by people who choose to work collaboratively towards shared goals while developing their learning, insights, knowledge, people skills and personal relationships through involvement in a PALAR project. The book provides a conceptual framework for action leadership and for the integrative, practical theory of PALAR; and examples of applications in higher education, management education for organization development, and community development. Readers are encouraged to adopt, adapt and further develop the evolving concepts of action leadership and PALAR in a participatory paradigm of learning, research and development.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 288 pp. Englisch.

  • Donald B. Brinkman

    Verlag: Springer Netherlands, Springer Netherlands Sep 2014, 2014

    ISBN 10: 9401781516 ISBN 13: 9789401781510

    Sprache: Englisch

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Taschenbuch. Zustand: Neu. Neuware -This volume celebrates the contributions of Dr. Eugene Gaffney to the study of turtles, through a diverse and complementary collection of papers that showcases the latest research on one of the most intriguing groups of reptiles. A mix of focused and review papers deals with numerous aspects of the evolutionary history of turtles, including embryonic development, origins, early diversification, phylogenetic relationships, and biogeography. Moreover it includes reports on important but poorly understood fossil turtle assemblages, provides historical perspectives on turtle research, and documents disease and variation in turtles. With its broad scope, which includes descriptions of material and new taxa from Australia, Asia, and Europe, as well as North and South America, this work will be an essential resource for anyone interested in the morphology and evolution of turtles. ¿This volume¿s breadth of time, geography, and taxonomic coverage makes it a major contribution to the field and a ¿must have¿ for all vertebrate paleontologists.¿, James F. Parham, California State University, CA, USA ¿A comprehensive and sweeping overview of turtle evolution by the top experts in the field that will interest everyone curious about these unique reptiles.¿ Jason S. Anderson, University of Calgary, Canada ¿An invaluable addition to the literature that covers the full spectrum of approaches toward understanding the evolution of these noble creatures.¿ Ann C. Burke, Wesleyan University, CT , USA ¿A truly comprehensive volume that both the student of fossil turtles, as well as the general reader interested in these enigmatic creatures, will find fascinating.¿ Tyler Lyson, Yale University, CT, USA¿Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 600 pp. Englisch.