Springer jun 2005 (17 Ergebnisse)

Buch. Zustand: Neu. Neuware - Many current texts in the area are just cookbooks and, as a result, students do not know why they perform the methods they are taught, or why the methods work. The strength of this book is that it readdresses these shortcomings; by using examples, often from real life and using real data, the authors show how the fundamentals of probabilistic and statistical theories arise intuitively.A Modern Introduction to Probability and Statistics has numerous quick exercises to give direct feedback to students. In addition there are over 350 exercises, half of which have answers, of which half have full solutions. A website gives access to the data files used in the text, and, for instructors, the remaining solutions. The only pre-requisite is a first course in calculus; the text covers standard statistics and probability material, and develops beyond traditional parametric models to the Poisson process, and on to modern methods such as the bootstrap.…

Taschenbuch. Zustand: Neu. Neuware - Testing is the primary hardware and software verification technique used by industry today. Usually, it is ad hoc, error prone, and very expensive. In recent years, however, many attempts have been made to develop more sophisticated formal testing methods. This coherent book provides an in-depth assessment of this emerging field, focusing on formal testing of reactive systems.This book is based on a seminar held in Dagstuhl Castle, Germany, in January 2004. It presents 19 carefully reviewed and revised lectures given at the seminar in a well-balanced way ensuring competent complementary coverage of all relevant aspects. An appendix provides a glossary for model-based testing and basics on finite state machines and on labelled transition systems. The lectures are presented in topical sections on testing of finite state machines, testing of labelled transition systems, model-based test case generation, tools and case studies, standardized test notation and execution architectures, and beyond testing.…

Taschenbuch. Zustand: Neu. Neuware - MARSWALK ONE: First Steps on a New Planet addresses the question of why we should embark on a journey to Mars, documenting what the first human crew will do when they place their feet in the red dust of the planet. The book also addresses why we need to carry out these tasks and, more importantly, what a human crew could achieve that an automated mission could not. Understanding the clear benefits of sending a human crew to the surface of Mars, and how these benefits can be seen back on Earth, is the key to sustained long-term public and political support for the programme in terms of cash and commitment.The book accepts that the journey will be made, but does not specify precisely when. Flight time, and how to get to and from the planet are discussed briefly, to understand why the suggested duration spent at Mars is reasonable.The main objective of the work is to look at what science will be done on the surface - supported by orbital operations - and what hardware and technology will be employed to achieve the mission objectives. This analysis is drawn from previous experiences in manned and unmanned space programmes, including Apollo, Skylab, Salyut/Mir, Shuttle and ISS, Viking, Luna/Lunokhod, and recent Mars missions such as Pathfinder and Global Surveyor.In addition, new interviews with key personalities involved in planning Martian exploration, and discussions about current thoughts on what we need to accomplish on Mars when we get there, will provide a lively and thought provoking account that could generate fresh debate.When the decision is finally made to go to Mars, it will be made in the knowledge that most of the world knows why we are going and what benefits mankind will see for the effort. The authors' primary objective is to begin this understanding.…

Taschenbuch. Zustand: Neu. Neuware - As everyone knows, intuition is warm and fuzzy, qualitative, not measurable. Economics, on the other hand, is quantitative, and if it is not a hard science, at least it is the 'queen of the social sciences.' It is, therefore, intuitively obvious, that intuition and economics are as if oil and water. The problem is, what is intuitively obvious is not always correct. And, there are two major reasons why intuition and economics are not like oil and water. First, economics concerns itself with decision making, and decisions are made in the brain. The human brain is the size of a grapefruit, weighing three pounds with approximately 180 billion neurons, each physically independent but interacting with the other neurons. What we call intuition is, like decision making, a natural information processing function of the brain. Second, despite the current emphasis on quantitative analysis and deductive logic there is a rich history of economists speaking about intuition. First, the human brain, specifically the neocortex, has a left and right hemisphere. The specialized analytical style of the left hemisphere and the specialized intuitive style of the right hemispheres complement each other.…

Buch. Zustand: Neu. Neuware - A collection of readily reproducible methods for the design, preparation, and use of RNAs for silencing gene expression in cells and organisms. The techniques range widely and include methods addressing the biochemical aspects of the silencing machinery, RNA silencing in non-mammalian organisms, and the in vivo delivery of siRNAs and silencing vectors. There are also techniques for designing, preparing, and using RNAs to silence gene expression, for fine-tuning regulation by targeting specific isoforms of a given gene, and for the study and use of microRNAs. The protocols follow the successful Methods in Molecular Biology(TM) series format, each offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.…

Buch. Zustand: Neu. Neuware - The idea of preparing a new critical edition of Elisha Bartlett's Essay on the Philosophy of Medical Science was suggested to me several years ago by Dr. H. Tristram Engelhardt, Jr. Since that time it has been a pleasure to get to know the life and work of Elisha Bartlett. I am pleased to be completing this book in the bicentennial year of Bartlett's birth. Bartlett was born in 1804 in Smithfield, Rhode Island, less than twenty-five miles from Worcester, Massachusetts, my present home-a short journey even in Bartlett's day. I have been able to walk at some of the sites to which Bartlett continually returned during his life. Visiting Bartlett's grave in the Slatersville cemetery has been an inspiration for the preparation of this book. Proximity to several institutions with rich holdings in Bartlett's works and in nineteenth-century American history of medicine greatly facilitated my research. First, though, I want to acknowledge the College of the Holy Cross for supporting my sabbatical leave for the academic year 2003-2004. The American Antiquarian Society, in Worcester, Massachusetts, was generous in giving me access to its remarkable resources. I was able to find many of Bartlett's published works and other nineteenth-century medical literature there, and the entire library staff provided quick and able research assistance.…

Buch. Zustand: Neu. Neuware - Around the world there is an increasing interest in issues of small business and entrepreneurship. In a time with a lot of myths and opinions of the role of entrepreneurs and small business it is vital for a book like this to encapsulate the knowledge that can be gained from the most significant research contributions in the field. Such knowledge is often build upon empirical oriented methods providing policy relevant results for small business owners and entrepreneurs.The aim of Pioneers in Entrepreneurship and Small Business Research is first to provide a historical-doctrinal review of the development of entrepreneurship and small business research and, second, to present some of the key pioneers that have shaped the research field during the past three decades. The book focuses on the first recipients of the FSF-NUTEK International Award for Small Business Research including David Birch, Arnold Cooper, David Storey, Ian MacMillan, Howard Aldrich, Zoltan Acs, David Audretsch, and Giacomo Becattini.…

Buch. Zustand: Neu. Neuware - Several years ago, when the discovery of catalytic RNA was recognized in a public manner,many people asked if new elds of therapy would soon be available. Although some tentative positive answers were given,nobody would say with certainty that RNA of various kinds was a truly promising means of altering gene expression. In fact,over the past decade,both our knowledge of RNAs with different functions and the utility of RNA in the inhibition or enhancement of gene expression have occurred with great drama. We proceeded in terms of possible therapeutic tools from RNase P and group I introns through hammerhead RNA enzymes, antisense technology, and more recently, to RNAi and its derivatives. A useful practical method of RNA delivery in animals will complete the picture. The diversity of RNA and the varied role of it inside cells and in therapy should be a tremendous challenge for young molecular biologists. This volume will make their task easier. Sidney Altman Sterling Professor of Molecular,Cellular & Devel- mental Biology,Nobel Laureate Department of Molecular,Cellular and Developm- tal Biology Yale University V NGTPR 4/23/05 1:00 PM Page VI VI Foreword Delivery of nucleic acids to cells in an animal remains a challenging problem. It is the major obstacle to success of therapeutic approaches using genes and oli- nucleotides,including siRNAs. Solutions found so far by chemists are satisfactory only for transfection of cells in culture.…

Taschenbuch. Zustand: Neu. Neuware -Analysis III. Applications, and IV. Contest: Social Milieus in Dortmund.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 704 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware - This volume contains revised versions of selected papers presented during the 28th Annual Conference of the Gesellschaft fur Klassi kation (GfKl), the German Classi cation Society. The conference was held at the Universit at Dortmund in Dortmund, Germany, in March 2004. Wolfgang Gaul chaired the program committee, Claus Weihs and Ernst-Erich Doberkat were the local organizers. Patrick Groenen, Iven van Mechelen, and their colleagues of the Vereniging voor Ordinatie en Classi catie (VOC), the Dutch-Flemish Classi cation Society, organized special VOC sessions. The programcommittee recruited17 notable and internationallyreno- ed invited speakers for plenary and semi-plenary talks on their current - search work regarding classi cation and data analysis methods as well as - plications.Inaddition,172invitedandcontributedpapersbyauthorsfrom18 countrieswerepresentedatthe conferencein 52parallelsessionsrepresenting the whole eld addressed by the title of the conference Classi cation: The Ubiquitous Challenge . Among these 52 sessions the VOC organizedsessions on Mixture Modelling, Optimal Scaling, Multiway Methods, and Psychom- ricswith18papers.Overall,theconference,whichistraditionallydesignedas an interdisciplinary event, again provided an attractive forum for discussions and mutual exchange of knowledge. Besides the results obtained in the fundamental subjects Classi cation and Data Analysis, the talks in the applied areas focused on various app- cation topics. Moreover, along with the conference a competition on Social Milieus in Dortmund , co-organized by the city of Dortmund, took place. Hence the presentation of the papers in this volume is arranged in the f- lowing parts: I. (Semi-)Plenary Presentations II. Classi cation and Data Analysis III. Applications, and IV. Contest: Social Milieus in Dortmund.…

Buch. Zustand: Neu. Neuware - Samuel A. Tisherman, MD', Fritz Sterz, MD~ '~niversit~ of Pittsburgh, Pittsburgh, PA, USA 2~edical University of Vienna, Vienna, Austria The use of hypothermia for a variety of therapeutic purposes has a long and erratic history. Hippocrates recommended the use of topical cooling to stop bleeding. Fay used cooling of the extremities for patients with tumors in the 1930s. It wasn't until the 1950s, when the effects of hypothermia on systemic oxygen metabolism became better defined, that systemic hypothermia became a commonly used modality, particularly for cardiac surgery. Hypothermia was used for protection (treatment before the insult) and preservation (treatment during the insult) of the heart and entire organism during planned operative ischemia. Shortly thereafter, attempts were made to use hypothermia for resuscitation (treatment after the insult) from cardiac arrest and for management of head trauma. At that time, it was felt that moderate hypothermia (28-32OC) was needed. This was difficult to achieve and manage. Multiple complications were noted. Consequently, therapeutic, resuscitative hypothermia lay dormant for many years while mild (32-35°C) to moderate hypothermia became common for many cardiothoracic and neurosurgical procedures. In the early 1990s, it was found that mild hypothermia, even after cardiac arrest, had benefit for the brain. Similar results were found with head trauma. This lead to a burst of enthusiasm for research into resuscitative hypothermia for a variety of insults, most of which have tissue ischemia as a major component.…

Buch. Zustand: Neu. Neuware - Information Processing and Security Systems is a collection of forty papers that were originally presented at an international multi-conference on Advanced Computer Systems (ACS) and Computer Information Systems and Industrial Management Applications (CISIM) held in Elk, Poland. This volume describes the latest developments in advanced computer systems and their applications within artificial intelligence, biometrics and information technology security. The volume also includes contributions on computational methods, algorithms and applications, computational science, education and industrial management applications.…

Buch. Zustand: Neu. Neuware - The majority of studies on the quality of life have been conducted in Western contexts and are based on Western participants. Comparatively speaking, there are only a few studies that have been conducted in different Chinese contexts. Also, there are fewer QOL studies based on children and adolescents, or studies that examine the relationship between QOL and economic disadvantage. In addition, more research is needed to address the methodological issues related to the assessment of quality of life.This volume is a constructive response to the challenges described above. It is the first book to cover research in Chinese, Western and global contexts in a single volume. It is a ground-breaking volume in which Chinese studies on the quality of life are collected. The book includes papers addressing family QOL, quality of life in adolescents experiencing economic disadvantage, and methodological issues in the assessment of QOL. It is written by researchers working in a variety of disciplines.…

Buch. Zustand: Neu. Neuware - The application of fractals in the engineering sciences is evolving swiftly and the editors have turned to Springer for the third time to bring you the latest research emerging from the rapid growth in techniques available for the employment of the ideas of fractals and complexity to a variety of disciplines in and associated with the engineering field. The strong potential of this research can be seen in real industrial situations with recent progress being made in areas such as chemical engineering, internet traffic, physics and finance. Image processing continues to be a major field of application for fractal analysis and is well-represented here.It is important to note that the applications models are presented with a firm basis in theoretical argument, the qualitative observation of fractal phenomena no longer being sufficient.Consisting of papers written by a world-wide pool of experts, the multidisciplinary approach of this third volume will be of particular interest to industrial researchers and practitioners as well as to academics from many backgrounds.Fractals in Engineering: New Trends in Theory and Applications continues the publication of engineering-related research in fractal techniques begun in Fractals in Engineering and Fractals: Theory and Applications in Engineering (Springer London 1997 and 1999).…

Buch. Zustand: Neu. Neuware - The morphology that results during the growth of a material on the substrate of a different material is central to the fabrication of all quantum heterostructures. This morphology is determined by several factors, including the manner in which strain is accommodated if the materials have different lattice constants. One of the most topical manifestations of lattice mis t is the formation of coherent thr- dimensional(3D)islandsduringtheStranski Krastanovgrowthofahighly-strained system. The prototypical cases are InAs on GaAs(001) and Ge on Si(001), though other materials combinations also exhibit this phenomenon. When the 3D islands are embedded within epitaxiallayers of a material that has a wider band gap,the carriers within the islands are con ned by the potential barriers that surround each island, forming an array of quantum dots (QDs). Such structures have been produced for both basic physics studies and device fab- cation, including QD lasers and light-emitting diodes (LEDs) operating at the c- mercially important wavelengths of 1.3 µ m and 1.55 µ m. On a more speculative level, QD ensembles have been suggested as a possible pathway for the solid-state implementation of a quantum computer. Although some of the principles of qu- tum computing have been veri ed by other means, the practical utilization of this new computingparadigmmay warrant some sort of solid state architecture. QDs are seen as possible components of such a computer, as evidenced by a number of papersappearingintheliteratureproposingQD-basedarchitecturesandworkshops that are being organized to explore these possibilities.…

Buch. Zustand: Neu. Neuware - Substantialfundamental workhas been undertaken inthe different aspects of impact biomechanics over the past three decades. Much of this has been motivated and undertaken bythe automotive industry intheirefforts to improve transport safety. More recently, however, it has become app- ent that themultidisciplinary synergies which are realisedby interactions between engineers, scientists and clinical practitioners will ultimately lead to a greater understanding of the complex interacting phenomena withinthe human bodyafter it has sustained an impact. In turn, this greater depth of knowledge will provide more fundamentalinsights into the analysis, d- gnosis, treatment and prevention ofimpact injuries across a broader sp- trum of accident environments. Thescienti c focus of this IUTAM symposium istoaddress those t- ics that are centrally important to the biomechanics ofimpact. These can be groupedinto those that are concerned with the different causes of - cidents (e. g. , transport, occupational and sports injuries), themechanics - volvedinaccident analysis (e. g. , accident investigation, computational m- elling techniques), the different types of resulting traumatic injuries (incl- ing musculoskeletal, organ, spinal and head injuries), methods of asse- ing the extent of injury (e. g. , injury assessment, injury criteria, constitutive laws for human tissue), and providing protection during an impact (e. g. , injury prevention, energy absorption materials, and safety devices).…

Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Psychopathie ist eine Persönlichkeitsstörung, die durch eine ausgeprägte Kombination von Verhaltensweisen und daraus gefolgerten Charaktereigenschaften definiert wird. Die meisten dieser Eigenschaften werden von der Gesellschaft als negativ angesehen; daher ist es keine Bagatelle, jemanden als Psychopathen zu diagnostizieren. Wie bei jeder psychiatrischen Störung basiert die Diagnose auf zusammengetragenen Indizien dafür, dass eine Person zumindest die Minimalkriterien der Persönlichkeitsstörung erfüllt. Bei Fällen aus meinen eigenen Akten sind die jeweiligen Personen sorgfältig auf der Basis umfangreicher Informationen aus Interviews und den Akten diagnostiziert worden. Allerdings habe ich diese Personen durch die Veränderung von Einzelheiten und das Entfernen von Identifikationsmerkmalen unkenntlich gemacht, ohne jedoch die zu treffende Aussage zu verfälschen. Wenn auch das Thema dieses Buches Psychopathie ist, so sind doch nicht alle hier beschriebenen Personen Psychopathen. Viele der verwendeten Beispiele stammen aus öffentlich zugänglichen Berichten, den Nachrichtenmedien und persönlichen Gesprächen, und ich kann nicht sicher sein, dass die jeweils in Frage stehenden Personen Psychopathen sind, selbst wenn sie von anderen so bezeichnet worden sind. In jedem Falle stehen aber die belegten Aussagen über einen Verhaltensaspekt der jeweiligen Person mit dem Konzept der Psychopathie in Einklang, oder sie illustrieren einen für die Persönlichkeitsstörung zentralen Charakterzug oder ein typisches Verhalten. Solche Personen könnten Psychopathen sein oder auch nicht. Aber die Berichte über ihr Verhalten sind ein nützliches Vehikel, um die verschiedenen Eigenschaften und Verhaltensweisen zu erörtern, die Psychopathie definieren.…