Springer jun 2004 (12 Ergebnisse)
- Hardcover
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Buch. Zustand: Neu. Neuware - This volume takes stock of the present state of Humanitarian Mine Action (HMA), looking at lessons that have been learned with the aim of further strengthening policies and practices in the future. It draws on the most recent findings from scholarly research and field programmes. Among the contribut…ors are academics, decision-makers and practitioners.
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Buch. Zustand: Neu. Neuware - This title is a must-read for anyone interested in deepening their understanding of the behaviours of children and adolescents. It focuses on measurement issues related to the subjective well-being of children and adolescents as opposed to current objective measurements. The volume contains eight ch…apters that represent a significant advancement in our understanding of life satisfaction in specific age groups, behavioural context, and cultures. The first chapter provides a synthesis of assessment research directed at children and youth. The subsequent chapters offer an in-depth look at subpopulations of youth and specific behaviours. Together the chapters demonstrate the importance of considering the role of life satisfaction across age groups and situations. This volume will be of interest to researchers in government and academia, social psychologists, those working in the prevention sciences, and others who focus on assessing the quality of life and well-being of children and adolescents.
- Hardcover
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Buch. Zustand: Neu. Neuware - Intracellular checkpoint controls constitute a network of signal transd- tion pathways that protect cells from external stresses and internal errors. Ext- nal stresses can be generated by the continuous assault of DNA-damaging agents, such as environmental mutagens, ultraviolet (UV) light, ionizing…radiation, or the reactive oxygen species that can arise during normal cellular metabolism. In response to any of these assaults on the integrity of the genome, the activation of the network of checkpoint control pathways can lead to diverse cellular responses, such as cell cycle arrest, DNA repair, or elimination of the cell by cell death (apoptosis) if the damage cannot be repaired. Moreover, internal errors can occur during the highly orchestrated replication of the cellular genome and its distribution into daughter cells. Here, the temporal order of these cell cycle events must be strictly enforced-for example, to ensure that DNA replication is c- plete and occurs only once before cell division, or to monitor mitotic spindle assembly, and to prevent exit from mitosis until chromosome segregation has been completed. Thus, well functioning checkpoint mechanisms are central to the maintenance of genomic integrity and the basic viability of cells and, the- fore, are essential for proper development and survival. The importance of proper functioning of checkpoints becomes plainly obvious under conditions in which this control network malfunctions and fails. Depending on the severity and timing, failure of this machinery can lead to embryonic lethality, genetic diseases, and cancer.
Sprache: Englisch
Verlag: Springer Nature B.V. Jun 2004, 2004
Serie: Buch 118 von 241 - NATO Science Series II: Mathematics, Physics and Chemistry
- Hardcover
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Buch. Zustand: Neu. Neuware - A masterly survey of the last 13 years of Very Long Baseline Interferometry, reviewed in light of the most advanced astronomical observations. Topics covered include: Nonthermal emission from extragalactic radio sources; Principles of synchrotron emission in relation to astrophysics; Theory of relat…ivistic jets; Young, powerful radio sources and their evolution; Scintillation in extragalactic radio sources; Radio and optical interferometry; Radio polarimetry; Unified schemes; Deep fields; Tropospheric and ionospheric phase calibration; Supernovae; VLBI for geodesy and geodynamics.
- Hardcover
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Buch. Zustand: Neu. Neuware - Trinucleotide repeats are relatively common in the human genome. These simple repeats have received much attention since epoch-making discoveries were made that particular trinucleotide repeats are expanded in the causal genes of human hereditary neurological disorders. For example, the CGG repeat i…s expanded in fragile X syndrome at the 5' untranslated region (UTR) of its causal gene. In myotonic dystrophy, it is the CTG repeat that is expanded at the 3' UTR of its causal gene. The CAG repeat was also found expanded in coding regions of the genes responsible for X-linked spinal and bulbar muscular atrophy, Huntington's disease, spinocerebellar ataxia, and other disorders. On the other hand, expansion of the GAA repeat was identified in the intron of the gene responsible for the Friedreich's ataxia. For these trinucleotide repeat diseases, the longer the trinucleotide expansion, the earlier the age of onset and the more severe the syndrome. Thus, these findings that showed the intriguing link between a particular trinucleotide expansion and its associated neurological disorders have led to a new field of intensive study. Active research addressing the underlying mechanisms for trinucleotide repeat diseases has employed various approaches ranging from DNA biochemistry to animal models for the diseases. In particular, animal models for the triplet repeat diseases have provided excellent resources not only for understanding the mechanisms but also for exploring therapeutic interventions.
- Hardcover
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Buch. Zustand: Neu. Neuware - In the past half century, filamentous fungi have grown in commercial importance not only in the food industry but also as sources of pharmaceutical agents for the treatment of infectious and metabolic diseases and of specialty proteins and enzymes used to process foods, fortify detergents, and perfo…rm biotransformations. The commercial impact of molds is also measured on a negative scale since some of these organisms are significant as pathogens of crop plants, agents of food spoilage, and sources of toxic and carcinogenic compounds. Recent advances in the molecular genetics of filamentous fungi are finding increased application in the pharmaceutical, agricultural, and enzyme industries, and this trend promises to continue as the genomics of fungi is explored and new techniques to speed genetic manipulation become available.This volume focuses on the filamentous fungi and highlights the advances of the past decade, both in methodology and in the understanding of genomic organization and regulation of gene and pathway expression.
- Hardcover
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Buch. Zustand: Neu. Neuware - Automatic Quantum Computer Programming provides an introduction to quantum computing for non-physicists, as well as an introduction to genetic programming for non-computer-scientists. The book explores several ways in which genetic programming can support automatic quantum computer programming and p…resents detailed descriptions of specific techniques, along with several examples of their human-competitive performance on specific problems. Source code for the author's QGAME quantum computer simulator is included as an appendix, and pointers to additional online resources furnish the reader with an array of tools for automatic quantum computer programming.
- Hardcover
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EUR 223,29
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Buch. Zustand: Neu. Neuware - The present volume contains the presentations of a NATO advanced Research Workshop (ARW) entitled 'The invasion of the Black, Mediterranean and Caspian Seas by the American Ctenophore, Mnemiopsis leidyi Agassiz: a multidisciplinary perspective and a comparison with other aquatic invasions', held on…24 - 26 June 2002 in Baku (Azerbaijan). The meeting was nanced by the NATO Division for Scienti c and Environmental Affairs (Brussels); substantial logistic support was provided by the CEP (Caspian Environmental Program) of the GEF in Baku. The Mediterranean, Black, and Caspian Seas represent three fragments of the former Tethys Sea, and are thus of great interest to understanding the evolution of the entire region where Eurasia, Africa and the Arabian Peninsula meet. While the Mediterranean is a typical marine environment, with salinity even a little above the world ocean's, the Black Sea is a brackish meromictic lake, and the Caspian is a lake with a saline gradient extending from a freshwater basin in the North to a brackish water basin in the South. Intense shing activity takes place in all three seas, while maritime traf c through the Dardanelles and Bosporus, and via the Lenin Canal (between the Don and Volga rivers) to the Caspian Sea has become greatly intensi ed in the course of the last few decades.
Sprache: Englisch
Verlag: Springer Nature B.V. Jun 2004, 2004
Serie: Buch 158 von 241 - NATO Science Series II: Mathematics, Physics and Chemistry
- Softcover
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Taschenbuch. Zustand: Neu. Neuware.
- Hardcover
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Buch. Zustand: Neu. Neuware - This book is the proceedings of the Falk Symposium No. 135 held in Prague, Czech Republic, on September 12-13, 2003, and is dedicated to the important issue of immunological aspects of diseases of the liver and gut. Without any doubt, immunological pathways are among the most important and universal… factors in the pathogenesis of all diseases. Their importance is also constantly increasing, because these principles have been adopted in clinical practice for both diagnostic and therapeutic procedures. Chapters by prominent experts will stimulate new ideas and set the scene for productive discussion on this topic.
Sprache: Englisch
Verlag: Springer Jun 2004, 2004
Serie: Buch 90 von 241 - NATO Science Series II: Mathematics, Physics and Chemistry
- Hardcover
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Buch. Zustand: Neu. Neuware - There is a growing understanding that the progress of the conventional silicon technology will reach its physical, engineering and economic limits in near future. This fact, however, does not mean that progress in computing will slow down. What will take us beyond the silicon era are new nano-techno…logies that are being pursued in university and corporate laboratories around the world. In particular, molecular switching devices and systems that will self-assemble through molecular recognition are being designed and studied. Many labora tories are now testing new types of these and other reversible switches, as well as fabricating nanowires needed to connect circuit elements together. But there are still significant opportunities and demand for invention and discovery be fore nanoelectronics will become a reality. The actual mechanisms of transport through molecular quantum dots and nanowires are of the highest current ex perimental and theoretical interest. In particular, there is growing evidence that both electron-vibron interactions and electron-electron correlations are impor tant. Further progress requires worldwide efforts of trans-disciplinary teams of physicists, quantum chemists, material and computer scientists, and engineers.
- Softcover
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Taschenbuch. Zustand: Neu. Neuware - Studi di grande interesse sperimentale e clinico sono stati condotti da numerosi ricercatori e clinici sull arresto cardiaco, tema-chiave in medicina, con l obiettivo di migliorare gli standards di prevenzione e trattamento della morte improvvisa. Tra gli studiosi di riferimento è di grande r…ilevanza il nome di Peter Safar, fondatore della Medicina del Malato Critico, recentemente scomparso e a cui la Scuola di Specializzazione in Anestesia e Rianimazione di Trieste vuole dedicare questo manuale, indirizzato a tutti gli operatori del settore.
