springer jun 1991 (16 Ergebnisse)

Taschenbuch. Zustand: Neu. Neuware - General Practice is undergoing the most major series of changes since the introduction of the National Health Service in 1948. They concern both concepts of care and practical details of the way care is delivered. In spite of the hostility generated by the changes most of the broad general concepts have been accepted. The principle of patients having more choice is widely supported, the inclusion of preventive medicine and anticipatory care in the responsibilities of practice has few opponents, the introduction of audit as a way of improving performance has been generally welcomed. Even the idea of putting GPs in better financial management of patients and drug budgets has had supporters in principle. The antipathy has generally related to the method of introduction of these changes. One important concern has been the time requirements of the New Contract and the feeling that these will erode the real nature of our work: the close personal relationship with patients. If we improve the quality of our management this is less likely to happen. We shall be able to work within the New Contract and retain the quality of service we pro vide. If we improve the understanding of our staff of what we are trying to achieve we are more likely to reach the targets that we set whilst keeping people happy. vii This book sets out to explain the New Contract.

Taschenbuch. Zustand: Neu. Neuware - Europe faces a challenge: how to apply information and communication technologies to health care. One problem is the widening gap between the expectations of citizens and the limited resources available to provide health services. It is here that advanced technology can serve as an important tool to find innovative and more efficient ways of delivering health services. This book reports the summary of a study performed under contract by a team of consultants for Directorate-General XIII of the Commission of the European Communities. It analyses the key factors governing the evolution of advanced information systems for health care and medicine in Europe and provides guidelines for placing current and future work within the framework of the Community research and development programmes.

Buch. Zustand: Neu. Neuware - 1 Why use histochemistry for a better understanding of pharmacology and toxicology .- 2 Whole-body autoradiography of pharmaceuticals and chemicals.- 3 Image analysis, fluorescence and laser microscopy.- 4 The measurement of free calcium to assess cellular function and injury using digital imaging fluorescence microscopy.- 5 Flow cytometry to characterize normal and abnormal cell function.- 6 Quantitative histochemical and cytochemical assays.- 7 Fixation of tissue for histochemistry.- 8 Immunochemical methods to assess cellular malfunction.- 9 Cell markers and processes related to chemically induced carcinogenesis.- 10 The mechanistic basis of chemical- and drug-induced nephrotoxicity.- 11 Pollutant-induced toxicity in the marine environment.

Buch. Zustand: Neu. Neuware - Advan ces in production technology.- System analysis of yield trials can raise efficiency of breeding for yield.- Research needs in the production of high quality seeds.- Breeding for quality and resistance to fusarial wilt in gladiolus.- Reproductive biology of potato: Basis for true seed production.- Resistance breeding under coordinated programme.- Quality improvement of Punjab grapes.- Exploitation of allien genes for yellow vein mosaic resistance in okra.- Use of vesicular-arbuscular mycorrhiza (VAM) as biofertilizer for horticultural plants in developing countries.- Foliar feeding of zinc and iron in peach.- Conservation of wild plants of horticultural importance from Tumkur district, Karnataka.- Potential of seed storage at ambient temperature using organic liquids to avoid refrigeration.- Chemical weeding as a labour saving device in management of fruit nurseries.- Role of germplasm in Citrus rootstock improvement.- Comparative efficacy of single and split applied nitrogen on yield and quality of 'Perlette' grapes.- Induced mutations recovered in M2 and subsequent generations in three varieties of okra (Abelmoschus esculentus (L.) Moench).- Plant genetic manipulation.- Role of viruses in plant biotechnology.- Microbial populations, host-specific virulence & plant resistance genes.- Genetically engineered resistance in plants against viral infection.- Genetic engineering and transformation of monocots for crop improvement.- Agrobacterium-mediated gene transfer in Citrus reticulata Blanco.- Regeneration and genetic transformation studies in watermelon (Citrullus vulgaris L. cv. Melitopolski).- Molecular aspects of cytokinin's stymied action on auxin-mediated new root formation in the hypocotyls of Phaseolus vulgaris L.- Plant cell and tissue culture.- Commercial aspects of micropropagation.- Large scale micropropagation: it's strategic use in horticulture.- Micropropagation of bulb crops.- Current status of forest biotechnology.- Large scale secondary metabolite production: the sanguinarine story.- Current research on micropropagation of Sulcorebutia alba Rausch, Syringa vulgaris L., Hip-peastrum hybrids and Tulipa hybrids.- Plant cell culture and food biotechnology: current trends and future prospects.- Tissue culture propagation: problems and potentials.- Micropropagation and plant conformity in Anthurium andreanum.- Rapid in vitro propagation of virus-indexed Freesia.- Effect of culture media and growth regulators on in vitro propagation of rose.- Shoot tip culture method for rapid clonal propagation of pomegranate (Punica granatum L.).- Tissue culture strategies for banana.- Gynogenic plants from ovary cultures of Mulberry (Morus indica).- Induction of high frequency somatic embryogenesis and plant regeneration in mandarins.- Tissue culture of medicinal plants: morphogenesis, direct regeneration and somatic embryogenesis.- Production of important phytochemicals through plant cell cultures and scale-up operations: limitations and prospects.- Establishment of somatic cell culture and plant regeneration in grapes (Vitis vinifera L.).- In-ovulo embryo culture in seedless grapes (Vitis vinifera L.).- Micropropagation of Davana (Artemisia pallens Wall.) by tissue culture.- Clonal propagation of bamboo, coffee and mimosa.- Greenhouse technology.- Greenhouse environmental control for Indian conditions.- New seed-grown cut flowers for floriculture industry.- Cut flowers in the Western Hemisphere.- Decision support for integrated greenhouse production systems.- Greenhouse pot plant production in the United States.- Robotics applications to transplanting of plug seedlings.- Plant health and crop protection.- Immunological and molecular approaches to the diagnosis of viruses infecting horticultural crops.- Viruses of ornamentals - identification and diagnosis.- Protein-A supplemented immune electron microscopy for diagnosis of potato viruses X, S, Y and leafroll.- Production of virus-tested seed potatoes.- Pesticide deconta.

Buch. Zustand: Neu. Neuware - Biophysics and Psychophysics of Photoreceptors.- Visual Pigments and Colour Vision in Primates.- The Cost of Trichromaticity for Spatial Vision.- Variability in Cone Populations and Implications.- Discussion: Biophysics and Psychophysics of Photoreceptor.- Transition from Photopic to Scotopic Light Assessments and Possible Underlying Processes.- Dual Rod Pathways.- Wavelength-Discrimination with Only Rods and Blue Cones.- Density of Bipolar Cells in the Macaque Monkey Retina.- Discussion: Rod Vision.- Parvocellular and Magnocellular Pathways and Psychophysics.- Which Cells Code for Color .- Receptive Field Structure of P and M Cells in the Monkey Retina.- On the Relation between Cellular Sensitivity and Psychophysical Detection.- P and M Pathway Specialization in the Macaque.- The Color-Opponent and Broad-band Channels of the Primate Visual System.- Discussion: P- and M-Pathways I.- Temporal Characteristics of Colour Vision: VEP and Psychophysical Measurements.- The Contribution of Colour to Motion.- Functional Classification of Parallel Pathways.- The Responses of Macaque Retinal Ganglion Cells to Complex Temporal Waveforms.- Remote Surrounds and the Sensitivity of Primate P-Cells.- On Neurophysiological Correlates of Simultaneous Colour and Brightness Contrast as Demonstrated in P-LGN-Cells of the Macaque.- Development of Infant Contrast Sensitivity and Acuity for Coloured Patterns.- Psychophysical Evidence of two Gradients of Neural Sampling in Peripheral Vision.- Discussion: P- and M-Pathways II.- Visual Evoked Potentials.- On the Nature of Visual Evoked Potentials, Unit Responses and Psychophysics.- Localization of the Electromagnetic Sources of the Pattern Onset Response in Man.- Discussion: Evoked Potentials.- Cortical Processing and Psychophysical Measurement.- Probing the Primate Visual Cortex: Pathways and Perspectives.- Lateral Interactions in Visual Cortex.- The Perceptual Significance of Cortical Organization.- Orientation and Spatial Frequency Selectivity: Properties and Modular Organization.- Orientation and Color Columns in Monkey Striate Cortex.- Discussion: Cortical Processing.- Psychophysical Studies and Post-Receptoral Processes.- Visual Photometry: Relating Psychophysics to some Aspects of Neurophysiology.- Sensory and Perceptual Processes in Seeing Brightness and Lightness.- Assimilation Versus Contrast.- On Achromatic Colors.- Color Opponency from Eye to Brain.- Chromatic Mechanisms beyond Linear Opponency.- Discussion: Psychophysics and Post-Receptoral Processes I.- Adaptation Mechanisms in Color and Brightness.- Testing the Contrast Explanation of Color Constancy.- Adaptation and Color Discrimination.- Studies on Colour Constancy in Man Using a 'Checkerboard - Mondrian'.- Discussion: Post-Receptoral Processes II.- Models, Neural Processes and Psychophysics.- Origin of Perceptually Measured Phase Shifts in the Visual System.- Psychophysical Correlates of Parvo Channel Function.- On the Physiological Basis of Higher Colour Metrics.- Neural Decoding.- Effects of Phase Shifts between Cone Inputs on Responses of Chromatically Opponent Cells.- Different Neural Codes for Spatial Frequency and Contrast.- Displacement Estimation, Stereo Matching and 'Object' Recognition: A Computer Simulation Approach Working with Real World Imagery.- Scaling and Thresholds of Color and Light Described by an Opponent Model of Color Vision Based on Psychophysical Data.- Discussion: Models and Neural Nets.- General Discussion.- Participants.

Buch. Zustand: Neu. Neuware - References . . . . . . . . . . . . . . . . . . . . . . . . . . . . 82 9 QUADRATIC 0-1 PROGRAMMING 8S 9. 1 Energy Minimization 86 9. 2 Notation and Tenninology . . . . . . . . . . . . . . . . . 87 9. 3 Minimization Technique . . . . . . . . . . . . . . . . . . 88 9. 4 An Example . . . . . . . . . . . . . . . . . . . . . . . . 92 9. 5 Accelerated Energy Minimization. . . . . . . . . . . . . 94 9. 5. 1 Transitive Oosure . . . . . . . . . . . . . . . . . 94 9. 5. 2 Additional Pairwise Relationships 96 9. 5. 3 Path Sensitization . . . . . . . . . . . . . . . . . 97 9. 6 Experimental Results 98 9. 7 Summary. . . . . . . . . . . . . . . . . . . . . . . . . . 100 References . . . . . . . . . . . . . . . . . . . . . . . . . . . . 100 10 TRANSITIVE CLOSURE AND TESTING 103 10. 1 Background . . . . . . . . . . . . . . . . . . . . . . . . 104 10. 2 Transitive Oosure Definition 105 10. 3 Implication Graphs 106 10. 4 A Test Generation Algorithm 107 10. 5 Identifying Necessary Assignments 112 10. 5. 1 Implicit Implication and Justification 113 10. 5. 2 Transitive Oosure Does More Than Implication and Justification 115 10. 5. 3 Implicit Sensitization of Dominators 116 10. 5. 4 Redundancy Identification 117 10. 6 Summary 119 References . . . . . . . . . . . . . . . . . . . . . . . . . . . . 119 11 POLYNOMIAL-TIME TESTABILITY 123 11. 1 Background 124 11. 1. 1 Fujiwara's Result 125 11. 1. 2 Contribution of the Present Work . . . . . . . . . 126 11. 2 Notation and Tenninology 127 11. 3 A Polynomial TlDle Algorithm 128 11. 3. 1 Primary Output Fault 129 11. 3. 2 Arbitrary Single Fault 135 11. 3. 3 Multiple Faults. . . . . . . . . . . . . . . . . . . 137 11. 4 Summary. . . . . . . . . . . . . . . . . . . . . . . . . . 139 References . . . . . . . . . . . . . . . . . . . . . . . . . . . . 139 ix 12 SPECIAL CASES OF HARD PROBLEMS 141 12. 1 Problem Statement 142 12. 2 Logic Simulation 143 12. 3 Logic Circuit Modeling . 146 12. 3. 1 Modelfor a Boolean Gate . . . . . . . . . . . . . 147 12. 3. 2 Circuit Modeling 148 12.

Buch. Zustand: Neu. Neuware - 1 Structures of and Bonding in Electronic Materials.- 1. Introduction.- 2. The Structure of the Group IV Elements and of III-V and II-VI Semiconductors.- 3. Bonding in and Relationships Between Zinc Blende and Wurtzite-Type Compounds.- 4. Other Structure Types.- References.- 2 Electron Energy Bands.- 1. Introduction.- 2. Models.- 2.1. The Nearly Free Electron Model.- 2.2. The Tight-Binding Model.- 2.3. The Relationship Between the Results of the Two Models.- 2.4. The Relationship Between Maximum Energy and k.- 2.5. Three-Dimensional Effects.- 2.6. Real Materials.- 3. Effective Mass.- 4. Positive Holes.- 5. Methods of Computing Band Structure.- 6. Conductance, the Octet Rule, and Bands.- 7. Postscript: The Kronig-Penney Model.- References.- 3 Electrical Properties of Semiconductors.- 1. Introduction.- 2. Intrinsic Semiconductors.- 3. Extrinsic Semiconductors.- 4. Scattering and Mobility of Charge Carriers.- 5. High-Field Effects.- 4 Optical Properties.- 1. Introduction.- 2. The Classical Approach.- 2.1. Relation to Conductivity.- 2.2. Optical Constants and Relative Permittivity.- 2.3. Resonance.- 3. Absorption Mechanisms.- 3.1. Fundamental Absorption.- 3.2. Other Mechanisms.- 4. Photoconductivity.- 5. Emission.- 5.1. Spontaneous Emission.- 5.2. Stimulated Emission.- 5.3. Nonradiative Recombination.- 6. Anisotropic Materials.- 7. Polarized Light.- 8. Thin-Film Systems.- 5 Interfaces and Low-Dimensional Structures.- 1. Introduction.- 2. Band Structure at a Heterojunction Interface.- 3. Low-Dimensional Effects.- 4. New Effects in Low-Dimensional Structures.- 5. Materials Growth.- 6. Other Low-Dimensional Structures.- 7. Applications.- 8. Conclusions.- References.- 6 Key Electrical Devices.- 1. Introduction.- 2. Basic Semiconductor Diodes.- 2.1. The p-n Junction Diode.- 2.2. The Metal-Semiconductor or Schottky Diode.- 2.3. Ohmic Contacts.- 3. Bipolar Junction Transisistors.- 4. Field Effect Transistors.- 4.1. MOSFETs.- 4.2. JFETs and MESFETs.- 5. Materials for Electronic Devices: The Significance of Silicon.- 6. Gallium-Arsenide-Based Transistors.- 6.1. The GaAs MESFET.- 6.2. Heterojunction-Based Devices.- 7. Other Materials.- 8. Conclusions and Future Prospects.- References.- 7 Key Optoelectronic Devices.- 1. Introduction.- 2. Materials Technologies.- 2.1. Important Optoelectronic Materials.- 2.2. Epitaxy.- 3. Light-Emitting Devices.- 3.1. Basic Principles.- 3.2. Light-Emitting Diodes (LEDs).- 3.3. Semiconductor Lasers.- 4. Optical Detectors.- 5. Waveguide Components.- 6. Optoelectronic Integrated Circuits.- 7. Conclusions.- 8 Thermodynamics and Defect Chemistry of Compound Semiconductors.- 1. Introduction.- 2. Elements of Multicomponent Phase Equilibria.- 2.1. Gibbs's Phase Rule.- 2.2. Pressure-Temperature Equilibrium.- 2.3. Solid-Liquid Equilibria in Multicomponent Systems.- 2.4. Representation of the Activity Coefficients.- 3. Solid-Liquid Phase Equilibria in Ternary III-V Compounds.- 4. Solid-Gas Phase Equilibria in Multicomponent III-V compounds.- 5. Native Point Defects in Compound Semiconductors.- 6. The Incorporation of Solute (Dopant) Atoms.- 7. Summary and Conclusions.- References.- 9 Single Crystal Growth I: Melt Growth.- 1. Introduction: General Principles.- 2. Role of Melt Growth.- 3. Constraints to Melt Growth.- 3.1. Chemical Reactivity.- 3.2. Vapor Pressure.- 3.3. Mechanical.- 3.4. Fundamental.- 4. Techniques of Melt Growth.- 4.1. Vertical Pulling or Czochralski Growth.- 4.2. Float Zone.- 4.3. Horizontal Bridgman.- 4.4 Liquid Encapsulation.- 5. Fundamentals.- References.- 10 Single Crystal Growth II: Epitaxial Growth.- 1. Introduction: General Principles.- 2. Role of Epitaxy.- 3. Constraints to Epitaxial Growth.- 3.1. Liquid Phase Epitaxy (LPE).- 3.2. Vapor Phase Epitaxy (VPE).- 4. Techniques of Epitaxial Growth.- 4.1. Liquid Phase Epitaxy.- 4.2. Vapor Phase Epitaxy: Conventional Inorganic Epitaxy.- 4.3. Molecular Beam Epitaxy (MBE): Metalorganic Molecular Beam Epitaxy (MOMBE).- 4.4. Metalorganic Vapor Phase Ep.

Buch. Zustand: Neu. Neuware - Thousands of articles and many books have been published on the acquired immunodeficiency syndrome (AIDS). There are, however, no studies or case reports and only several articles published on the anesthetic considerations for a person with AIDS or in pain with AIDS. There is no literature on the pain management of AIDS patients. Writing on this subject must be considered trailblazing. The reason anesthesiologists should know about AIDS has rapidly extended from concern over transmission of infection to anesthetic and analgesic considerations. The anesthesiologist may also be part of a pain management team on either an acute or a chronic pain service. The requirement may be to treat an HIV -positive or AIDS patient acutely postoperatively or in consult to a psychiatric, medical, or surgical service. In a pain clinic setting, the anesthesiologist may be concerned with diagnosis, treatment, or referral for other multidisciplinary consultation. The earlier question of central nervous system involvement in AIDS is now moot, rapidly replaced with the knowledge that the eNS, if not primarily infected, is so shortly thereafter. Protected by the blood-brain barrier, the eNS becomes both a sanctuary and reservoir for HIV. Because neurologic complications of HIV are common, and since knowledge of the nervous system is essential for anesthetic and pain management, it is important to review HIV infection of the nervous system.

Buch. Zustand: Neu. Neuware - Describing and designing complex electronic systems has become an overwhelming activit)' for which VHDL is showing increasingly useful and promising support. Although created as a description language. VHDL is being increasingly used as a simulatable and synthcsizablcdcsign language. For the first time, here is abook which describesa number of unique and powerful ways VHDL can be used to solve typical design problems in systems ones which must be designed correctly in vcry short periodsoflime. Typically useful lcchniquessuch as switch-level modeling, mixed analog and digital modelling, and advanced synthesis for which VHDL showsgrealpromisearefully presented. Thesemeth ods are bOlh immedial.ely applicable. and indicale lIle potential of VHDL in efficiently modelling Ihe real worldofelectronic systems. Sinceitsinception.there hasbeen adesireforananalogdescription languageconsistent with (and integrated with) VHDL. Until recently. VHDL could onl)' be applied to digital circuits.ootlhedreamofdescribingandsimulatingmixedanalogand digitalcircuitsis now a reality as described herein. Describing the functionality of analog circuits including intetoperability with digital circuits using the VHDL paradigm is surprisingly easy and powerful. The approach outlined by the authors presages a significant advance in the simulation of mixed systems.

Buch. Zustand: Neu. Neuware - International comparisons of economic institutions and government poli cies are fraught with difficulties. After1he selective barriers of language and culture are overcome, differences in programs and outcomes are far more subtle than those that can be revealed by highly aggregated national data. Rela tively 'soft' comparisons are the norm in international comparative research. This is particularly true in comparative analyses of housing and the operation of housing markets. Housing markets are local or regional in character, and the effects of government programs on market outcomes depend upon important economic characteristics of the local environment. Moreover, the institutions that influence the production, distribution, and consumption of housing differ enormously across nations. The distribution of housing and the role of the market in provision depend upon historical and social factors as well. Aggregate national data are unlikely to allow for much depth in comparisons across societies. Yet in the absence of such comparisons, the very visibility of housing may lead to inadequate or erroneous generalizations. Photographs emphasing the aesthetics of ''well planned' housing agglomorations or urban slums are compelling. Documen tation that middle-class households must wait in a queue for a decade to be housed is notably less graphic.

Buch. Zustand: Neu. Neuware - Guest Editor: JOSEF A. NOSSEK This is a special issue of the Journal of VLSI Signal Processing comprising eight contributions invited for publica tion on the basis of novel work presented in a special session on 'Parallel Processing on VLSI Arrays' at the International Symposium on Circuits and Systems (ISCAS) held in New Orleans in May 1990. Massive parallelism to cope with high-speed requirements stemming from real-time applications and the restrictions in architectural and circuit design, such as regularity and local connectedness, brought about by the VLSI technology are the key questions addressed in these eight papers. They can be grouped into three subsections elaborating on: ¿ Simulation of continuous physical systems, i. e. , numerically solving partial differential equations. ¿ Neural architectures for image processing and pattern recognition. ¿ Systolic architectures for implementing regular and irregular algorithms in VLSI technology. The paper by A. Fettweis and O. Nitsche advocates a signal processing approach for the numerical integration of partial differential equations (PD Es). It is based on the principles of multidimensional wave digital filters (MDWDFs) thereby preserving the passivity of energy dissipating physical systems. It is particularly suited for systems ofPDEs involving time and finite propagation speed. The basic ideas are explained using Maxwell's equa tions as a vehicle for the derivation of a multidimensional equivalent circuit representing the spatially infinitely extended arrangement with only very few circuit elements.

Buch. Zustand: Neu. Neuware - Bound and Referential Pronouns.- Logical Form and Barriers in Navajo.- Towards a Modular Theory of Coreference.- Head Government in LF-Representations.- Logical Structure in Syntactic Structure: The Case of Hungarian.- In Defense of the Correspondence Hypothesis: Island Effects and Parasitic Constructions in Logical Form.- Construing WH.- Two Properties of Clitics in Clitic-Doubled Constructions.- LF Movement in Iraqi Arabic.- List of Contributors.

Buch. Zustand: Neu. Neuware - A manipulator, or 'robot', consists of a series of bodies (links) connected by joints to form a spatial mechanism. Usually the links are connected serially to form an open chain. The joints are either revolute (rotary) or prismatic (telescopic), various combinations of the two giving a wide va riety of possible configurations. Motive power is provided by pneumatic, hydraulic or electrical actuation of the joints. The robot arm is distinguished from other active spatial mechanisms by its reprogrammability. Therefore, the controller is integral to any de scription of the arm. In contrast with many other controlled processes (e. g. batch reactors), it is possible to model the dynamics of a ma nipulator very accurately. Unfortunately, for practical arm designs, the resulting models are complex and a considerable amount of research ef fort has gone into improving their numerical efficiency with a view to real time solution [32,41,51,61,77,87,91]. In recent years, improvements in electric motor technology coupled with new designs, such as direct-drive arms, have led to a rapid increase in the speed and load-carrying capabilities of manipulators. However, this has meant that the flexibility of the nominally rigid links has become increasingly significant. Present generation manipulators are limited to a load-carrying capacity of typically 5-10% of their own weight by the requirement of rigidity. For example, the Cincinatti-Milicron T3R3 robot weighs more than 1800 kg but has a maximum payload capacity of 23 kg.

Buch. Zustand: Neu. Neuware - 'Now, however, weface an Age of Discontinuity in world economy and tech nology. We might succeed in making it an age of great economic growth as weil. But the one thing that is certain so far is that it will be a period of change-in technology and in economic policy, in industry structures and in economic theo ry, in the knowledge needed to govern and manage, and in economic issues. While we have been busy finishing the great nineteenth-century economic ed ijice, the foundations have shifted beneath our feet.' Peter F. Drucker, 1968 The A~e Qf DiscQntinuity, p. 10 This project has had a lQng gestatiQn period, probably ultimately dating to a YQuthful QbsessiQn with watershed divides and bQundaries. My awareness Qf the problem Qf discQntinuity in eCQnQmics dates tQ my first enCQunter with the capi tal theQry paradQxes in the late 1960s, the fruits Qf which can be seen in Chapter 8 Qf this book. This awareness led tQ a frostratiQn Qver the apparent lack Qf a mathematics Qf discQntinuity, a lack that was in the process of rapidly being QverCQme at that time.

Buch. Zustand: Neu. Neuware - Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy The few general oncology textbooks are generally out of date. Single papers in specialized journals are informative, but seldom comprehensive; these are more often preliminary reports on a very limited number of patients. Certain general journals frequently publish good in-depth reviews of cancer topics, and published symposium lectures are often the best overviews available. Unfor tunately, these reviews and supplements appear sporadically, and the reader can never be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes that aim to meet this need. It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, which is revised frequently to keep the coverage up to date, and which is easily available on a single library shelf or by a single personal subscription. We have approached the problem in the following fashion: first, by dividing the oncology literature into specific subdivisions, such as lung can cer, genitourinary cancer, pediatric oncology, etc.; and second, by asking eminent authorities in each of these areas to edit a volume on the specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current diag nosis, staging, markers, all forms of treatment modalities, basic biology, and more.

Buch. Zustand: Neu. Neuware - 'Overall, this volume should be useful to those wanting to update their knowledge of hepatic metabolism and transport of bile salts, and of phase II drug metabolism, and, in particular, glucuronidation. In addition, many of the chapters are well written and should be easily accessible to workers in all fields of hepatology, providing interesting new perspectives on several aspects of hepatic metabolism.' Alternatives for Laboratory 20 1992 'A must for anyone working in or interested in this field.' Unlisted Drugs Feb 1993.