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Taschenbuch. Zustand: Neu. Neuware - The Screen Design Manual provides designers of interactive media with a practical working guide for preparing and presenting information that is suitable for both their target groups and the media they are using. It highlights background information and relationships, clarifying them with exa…mples, and encourages the further development of the language of digital media. In addition to the basics of perception and learning psychology, ergonomics, communication theory, imagery research, and aesthetics, the book also considers design navigation and orientation elements. Guidelines and checklists, along with the comprehensive design of the book, support the transfer of information into practice.

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Taschenbuch. Zustand: Neu. Neuware - The present fifth conference in this series - counting the 1956 conference in Mainz the same way as the 'zeroth' symphonies of Beethoven and Bruckner - was held in conjunction with the centennial of the 'Convention du Metre' which was signed May 20, 1875 in Paris, Because of this occasion, an… extensive honorary committee was appointed: Honorary Committee; Chairman A. Kastler R. C. Barber(M) W. H. Johnson(M) K. Ogata(M) u. Bonse E. R. Cohen(M) Y. Sakurai A. H. Cook J. H. Sanders(M) P, Dean H. H. Staub(M) R. D, Deslattes U. Stille(M) J. V. Dunworth J, Terrien(M) V. I. Goldanskii(M) M. A. Thompson P. Grivet A. H. Wapstra(M) The members (marked M) of the Commission on Atomic Masses and Fundamental Constants of the International Union of Pure and Applied Physics belonged ex officio to this Committee, The Organizing Committee; chairman A, Horsfield H. Capptuller J . E. Faller J . L. Hall B. W. Petley B. N. Taylor was helped by the following two committees: v vi PREFACE Program Committee; chairman A. H. Wapstra c. Audoin W. H. Johnson W. Benenson R. Klapisch E. R. Cohen A. Rytz P. Giacomo J. H. Sanders Local Committee; chairman P. Grivet c. Audoin R. Klapisch N. Elnekave Y. Le Gallic s. Gerstenkorn P. Petit F. Hartmann M.

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Taschenbuch. Zustand: Neu. Neuware.

Sprache: Englisch
Verlag: Springer Nature B.V. Jan 2013, 2013
Serie: Buch 80 von 292 - IFIP Advances in Information and Communication Technology
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Taschenbuch. Zustand: Neu. Neuware.

Sprache: Englisch
Verlag: Springer Nature B.V. Jan 2013, 2013
Serie: Buch 82 von 292 - IFIP Advances in Information and Communication Technology
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Sprache: Englisch
Verlag: Springer Nature B.V. Jan 2013, 2013
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Taschenbuch. Zustand: Neu. Neuware - Included in this volume is a broad range of topics. Immunology is such a diverse field that many of the subspecialties overlap, and one finds it convenient and necessary to integrate information from several of them. We try to focus on the molecular aspects of immunology as much as is reasona…ble, but some con tributions consist of ablend of molecular and cellular immunology and even immunopathology. This is as it should be, since information at the molecular level often provides an explanation of phenomena observed at other levels. Myelin basic protein holds the interest of immunologists because it is impli cated in the induction of the autoimmune disease called experimental allergie encephalomyelitis (EAE). Although much biochemical and immunological information about this protein has been uncovered, it is not understood how such an inaccessible self-antigen can serve as the focal point in the central ner vous system for myelin basic protein-specific EAE-inducing T cells. Day dis cusses the problem by first reviewing the sequences of the proteins from several species and the antigenicity of the proteins and peptides derived from them. The reader is then led into a thorough discussion of the immunological relation ships that do and do not influence development of the encephalitis. From this discussion, the author promulgates the bystander model as the best overall mechanism to explain why different fragments of the highly conserved protein are needed by various species to give rise to the same type of localized central nervous system disease.

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Taschenbuch. Zustand: Neu. Neuware - Since the discovery that neuronal transmission can be chemically mediated, a large number of compounds have been found in the mammalian central nervous system which appear to function as neurotransmitter agents. Recently, electrophysiological and biochemical methods have been developed which…have enabled neuroscientists to classify better the myriad of neurotransmitter receptor sites in brain and to study their properties in finer detail. As a result of these investigations, a significant number of new discoveries have been made about the mechanisms involved in neurotransmitter receptor interactions, the role neurotransmitters play in the actions of pharmacological agents and in the pathogenesis of various neuropsychiatric disorders. The present two volume text was compiled to summarize the information relating to the physiological, biochemical, pharmacological and functional characteristics of neurotransmitter receptor sites. While emphasis is placed on neurotransmitter receptors in the mammalian central nervous system, the characteristics of these receptors in other species, both vertebrate and invertebrate, are also discussed where appropriate. While these books cover the major classes of putative neurotransmitters - amino acids, peptides and biogenic amines - and are therefore broad in scope, each is discussed in a concise fashion to highlight the major points of historical and contemporary interest. In addition to outlining data, each chapter addresses current theories relating to the various aspects of receptor properties and function in an attempt to reveal the directions of future research and as a stimulus for other workers in the field.

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Taschenbuch. Zustand: Neu. Neuware -1 The Fundamental Constants and Metrology.- 2 Gamma rays.- 3 Alpha and Beta Decays.- 4 Nuclear Reactions.- 5 Mass Spectrometry.- 6 Theory of Nuclear Binding Energies.- 7 Atomic Mass Formulae.- 8 Time and Frequency Measurements and the Speed of Light.- 9 Wavelength Comparison.- 10 The Josephson… Effects and 2e/h.- 11 Magnetic Moments.- 12 Miscellaneous Constants.- 13 Relativity, Time Variation of the Constants, and Philosophical Considerations.- 14 Evaluation.- 15 Conference Summary. 720 pp. Englisch.

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Taschenbuch. Zustand: Neu. Neuware - For many healthcare professionals, musculoskeletal diseases represent the 'bread and butter' topic after graduation. Therefore, radiological education in respect of the musculoskeletal system is vital in ensuring adequate patient management and cost-effective use of healthcare financial resou…rces. This book illustrates the clinical anatomy of the musculoskeletal system by means of images obtained using commercially available imaging equipment and the three main imaging techniques employed today - magnetic resonance imaging, computed tomography, and ultrasound. Based on an integrated multimodality approach, each anatomical region is presented with a special focus on clinically relevant anatomical details and the characteristic findings observed in patients referred by physicians. With almost 450 images and illustrations, A Radiologically Guided Approach to Musculoskeletal Anatomy is intended as a bridge from a standard anatomical atlas to diagnostic imaging. It will assist in the everyday interpretation of imaging studies of the musculoskeletal system, providing prompt answers to frequently encountered questions. Clinical notes and self-assessment modules are also provided. All who wish to learn more about the role of diagnostic imaging of the musculoskeletal system will find this book to be of great value. It will benefit not only medical students and residents but also radiology technologists and professionals in other fields of health care, including orthopaedists, rheumatologists, and rehabilitation specialists.

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Buch. Zustand: Neu. Neuware - From the contents: C. Brater and M. D. Murray: The effects of NSAIDs on the kidney G. Edwards and A. H. Weston: Latest developments in potassium channel modulator drugs M.R. Juchau and Y. Huang: Chemical teratogenesis in humans: Biochemical and molecular mechanisms S.P. Gupta: Studies on cardiovascu…lar drugs G. Polak: Antifungal chemotherapy: An everlasting battle O. Valdenaire: New insights into the bioamine receptor family.

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Taschenbuch. Zustand: Neu. Neuware - In their classic paper in 1929, Drury and Szent-Gyorgyi described a number of the important cardiovascular actions of adenosine. Another thirty years were to pass before the possible physiological role of adenosine in coronary vasodilation was studied by Berne and others. Since then, there ha…s been a tremendous increase in research into the actions of adenosine. Workers from many disciplines have employed a wide variety of techniques, since adenosine is a product of and a substrate for a number of metabolic pathways, is transported into cells, and acts at discrete receptor sites to modulate the activity of adenylate cyclase and to produce important actions on many cells and tissues including platelets, adipo cytes, heart, blood vessels, and other smooth muscles. International symposia on the actions of adenosine were held in 1978, 1981, and 1982, and the proceedings of these symposia have been published (Baer and Drummond, 1979; Daly et at., 1983; Berne et at., 1983). Since it is not the primary purpose of the present volume to review our current understanding of the nu merous actions of adenosine, these volumes should be consulted for such details. Rather, the present volume has been planned to provide both graduate students and investigators in pharmacology and related disciplines with a summary of some of the methods now available for the study of the actions of adenosine and, in particular, to highlight their possible uses and limitations.

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Taschenbuch. Zustand: Neu. Neuware - The Cell Biology of Fibroblast Cyclooxygenase.- Arachidonic Acid Metabolism During Interactions Between Glomerular and Bone Marrow-derived Cells.- Lipoxygenase Products and Their Functions in Glomeruli.- The Development of New Antileukotriene Drugs: Specific Leukotriene D4 Antagonists and 5-L…ipoxygenase Inhibitors.- The Renal Cytochrome P450 System Generates Novel Arachidonic Acid Metabolites.- The Biosynthesis and Actions of Prostaglandins in the Renal Collecting Tubule and Thick Ascending Limb.- Peptide Hormones, Cytosolic Calcium and Renal Epithelial Response.- Prostaglandins, Thromboxane and Leukotrienes in the Control of Mesangial Function.- Interactions of Platelet Activating Factor and Prostaglandins in the Glomerulus and in Mesangial Cells.- Eicosanoids and Platelet Activating Factor as Possible Mediators of Injury in Experimental Nephropathies.- Eicosanoids: Role in Experimental Renal Disease.- Abnormalities of Glomerular Eicosanoid Metabolism in States of Glomerular Hyperfiltration.- Diabetic Nephropathy: Pathophysiology, Clinical Course and Susceptibility.- The Molecular, Biochemical and Human Pharmacology of Thromboxane A2 in Renal Disease.- Studies of Renal Eicosanoid Synthesis In Vivo and In Vitro.- The Role of Eicosanoids in Human Glomerular Disease.

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Taschenbuch. Zustand: Neu. Neuware - It is now well known that the concept of drifting continents became an estab lished theory during the 1960s. Not long after this 'revolution in the earth sciences,' researchers began applying the continental drift model to problems in historical biogeography. One such problem was the origin a…nd dispersal of the New World monkeys, the Platyrrhini. Our interests in this subject began in the late 1960s on different conti nents quite independent of one another in the cities of Florence, Italy, and Berkeley, California. In Florence in 1968, A. B. Chiarelli, through stimulating discussions with R. von Koenigswald and B. de Boer, became intrigued with the possibility that a repositioning of the continents of Africa and South America in the early Cenozoic might alter previous traditional conceptions of a North American origin of the Platyrrhini. During the early 1970s this con cept was expanded and pursued by him through discussions with students while serving as visiting professor at the University of Toronto. By this time, publication of the Journal of Human Evolution was well underway, and Dr. Chiarelli as editor encouraged a dialogue emphasizing continental drift models of primate origins which culminated in a series of articles published in that journal during 1974-75. In early 1970, while attending the University of California at Berkeley, R. L. Ciochon was introduced to the concept of continental drift and plate tectonics and their concomitant applications to vertebrate evolution through talks with paleontologist W. A. Clemens and anthropologist S. L. Washburn.

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Taschenbuch. Zustand: Neu. Neuware - More than for any other volume of the Handbook of Neurochemistry, the chap ters in this volume on Pathological Neurochemistry deal with the interface of the laboratory bench with the patient's bedside. Most of the chapters reflect the confluence of basic scientists, clinical investigators, an…d physicians. Con sidered here are many of the more important disorders that afflict the nerves, muscles, spinal cord, and/or brain of mankind throughout the world. There are well over 500 such disorders. And our understanding of their nature and of measures for effective prevention or treatment depends significantly on appli cation of the biochemical disciplines that characterize neurochemistry. Before World War II, any attempt to compile a volume on pathological neurochemistry would have been largely descriptive and very rudimentary, as such 'handbooks' by Hans Winterstein (1929), Irvine Page (1937), and others demonstrate. But thanks to the many major advances in research and tech nology in the postwar decades, we now stand at the threshold of understanding how to manage many of the major neurological disorders, and we may expect more such delineations in the immediate decades ahead. Neurochemistry, de fined broadly, has played a central role in this extraordinary turn of events, progressing from what J. L. W, Thudichum in 1884 called objects of anxious empiricism to his anticipation of the proud exercise of chemical precision.