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Taschenbuch. Zustand: Neu. Neuware - 'Neuromuscular Quick Pocket Reference' provides easy and efficient access to common physical examination techniques and other neurological tests performed in a broad range of specialties. Mainly composed of tables, charts, and photographs, this handy reference puts together and organizes the information that clinicians use on a daily basis. The first part of the book covers musculoskeletal physical exam by region. Each entry is formatted and includes test name(s), purpose, techniques, clinical findings for positive test, sensitivity, specificity, and sources. Photographsshowing proper placement and action accompany most entries and provide a visual blueprint for successfully replicating tests in the exam room. The second part of the book is devoted to common neurological tests and scales for onthe-go reference, including muscles, motor points, dermatomes and myotomes, spasticity findings, radiculopathies, traumatic brain injury assessment, stroke scales, pressure ulcers, and much more.

Buch. Zustand: Neu. Neuware - The center of our Solar System is a star, one among billions of stars in our own galaxy. This star, which we call the Sun, gives rise to all life on Earth, is the driver of the photosynthesis in plants, and is the source of all food, energy, and fossil fuels on Earth.For us humans, the Sun as seen with the naked eye appears as a static and quiet yellow disk in the sky. However, it is in fact a stormy and variable star and contributes much more than only light and heat. It is the source of the beautiful northern and southern lights and can affect our technology-based society in many ways.The Sun is, like astronomy in general, a good entrance to natural science, since it affects us in so many ways and connects us to many other fields of science, such as physics, chemistry, biology, and meteorology.The book includes additional material on Springer Extras, a large number of animations and video material. A PowerPoint presentation of the book is also included there as a useful resource for teachers.

Taschenbuch. Zustand: Neu. Neuware - During the last annual meeting of the Austrian Society for Electron Microscopy it was decided to organize scientific symposia dealing with basic problems of cytology. If possible such symposia should be arranged in cooperation with other scientific societies. We intended to arrange symposia on special fields, to be presented on several aspects by excellent scientists invited. 'Neural Transmission' was chosen as a central topic for this first symposium. The subject represents a most rapidly expanding field of research and is of particular interest to morphologists, physiologists, pharmacologists, biochemists and clinicians. We are indebted to all the invited speakers for contributing their interesting papers. I feel bound to thank once more the firm of Bender, a subsidiary company of Boehringer Ingelheim and of Arzneimittelforschung Ges. m. b. H. Wien, for the generous financial support which made possible to realize the symposium. The publication of this volume, representing the papers and discussions originally read at the symposium and elaborated by the authors in detail and more extensively, was only made possible by the generous cooperation of the Springer-Verlag Vienna.

Taschenbuch. Zustand: Neu. Neuware - The design and analysis of data structures and efficient algorithms has gained considerable importance in recent years. The concept of 'algorithm' is central in computer science, and 'efficiency' is central in the world of money. I have organized the material in three volumes and nine chapters. Vol. 1: Sorting and Searching (chapters I to III) Vol. 2: Graph Algorithms and NP-completeness (chapters IV to VI) Vol. 3: Multi-dimensional Searching and Computational G- metry (chapters VII and VIII) Volumes 2 and 3 have volume 1 as a common basis but are indepen dent from each other. Most of volumes 2 and 3 can be understood without knowing volume 1 in detail. A general kowledge of algorith mic principles as laid out in chapter 1 or in many other books on algorithms and data structures suffices for most parts of volumes 2 and 3. The specific prerequisites for volumes 2 and 3 are listed in the prefaces to these volumes. In all three volumes we present and analyse many important efficient algorithms for the fundamental computa tional problems in the area. Efficiency is measured by the running time on a realistic model of a computing machine which we present in chapter I. Most of the algorithms presented are very recent inven tions; after all computer science is a very young field. There are hardly any theorems in this book which are older than 20 years and at least fifty percent of the material is younger than 10 years.

Buch. Zustand: Neu. Neuware - Art, or Science Which of these is the right way to think of the field of visualization This is not an easy question to answer, even for those who have many years experience in making graphical depictions of data with a view to help people understand it and take action. In this book, Graham Wills bridges the gap between the art and the science of visually representing data. He does not simply give rules and advice, but bases these on general principles and provide a clear path between them This book is concerned with the graphical representation of time data and is written to cover a range of different users. A visualization expert designing tools for displaying time will find it valuable, but so also should a financier assembling a report in a spreadsheet, or a medical researcher trying to display gene sequences using a commercial statistical package.

Taschenbuch. Zustand: Neu. Neuware - The Bloomsbury Series in Clinical Science is growing and changing. Its Editorial Board and contributors were all originally selected from, or had links with, the University College and Middlesex School of Medicine. Now, as the Series develops, board members and con tributors alike identify with the wider reaches of Bloomsbury and Islington. The aims of the Series remain, however, to highlight, to review and to record significant areas of research and development in the field of clinical science. All contributors are experts in their particular field and monographs may be the work of a single author or several, guided by individual editors. Diseases in the Homosexual Male is the third monograph in the Series. Edited by Michael Adler, Professor of Genito-Urinary Medicine at the University College and Middlesex School of Medicine, it presents contributions from a number of distinguished workers with special expertise. AIDS has perhaps highlighted the problem but this monograph illustrates the wider profile and gives wit ness to the multidisciplinary nature of clinical science.

Taschenbuch. Zustand: Neu. Neuware - The development of immunization has been one of the most striking features in the control of infectious disease in the twentieth century. This book takes into account the need for a simple, concise account of immunization procedures not only in the UK and USA but also in other countries, and to this end a special chapter on immunization in developing countries has been included. Following two introductory chapters, there are nine chapters on various diseases and the vaccines that have been developed to combat them. In each of these chapters, a short discussion of the epidemiology of the disease and the history of immunization against it is followed by a description of the vaccine, its efficacy, contraindications to its use and future developments. These are followed by four general chapters on vaccines for travel, vaccines for selective use, passive immunization and immunization in tropical environments and the book concludes with a chapter on the smallpox vaccination and one on new vaccines. The demand for this book follows the popularity of a series of articles on immunization which appeared in Update. These have been expanded and largely rewritten. I have drawn on many expert sources and have made an effort to provide a balanced and non-controversial opinion with a discussion of alternative procedures where indicated.

Taschenbuch. Zustand: Neu. Neuware - Atrial fibrillation is a common and important arrythmiawhich affects nearly5% of peopple over 70. This synthesisof current knowledge which is based onmuch original work bythe author brings togeher for the first time the many areasof advance in recent years and will help to make expertsfrom the highly specialised fields within cardiology awareof the developments withinothers.

Taschenbuch. Zustand: Neu. Neuware - This volume is on 'modem geometric computing for visualization' which is at the forefront of multi-disciplinary advanced research areas. This area is attracting intensive research interest across many application fields: singularity in cosmology, turbulence in ocean engineering, high energy physics, molecular dynamics, environmental problems, modem mathe matics, computer graphics, and pattern recognition. Visualization re quires the computation of displayable shapes which are becoming more and more complex in proportion to the complexity of the objects and phenomena visualized. Fast computation requires information locality. Attaining information locality is achieved through characterizing the shapes in geometry and topology, and the large amount of computation required through the use of supercomputers. This volume contains the initial results of our efforts to satisfy these re quirements by inviting experts and selecting new research works through review processes. To be more specific, this book presents the proceedings of the International Workshop on Modem Geometric Computing for Visualization held at Kogakuin University, Tokyo, Japan, June 29-30, 1992 organized by the Computer Graphics Society, Japan Personal Com puter Software Association, Kogakuin University, and the Department of Information Science, Faculty of Science, The University of Tokyo. We received extremely high-quality papers for review from five different countries, one from Australia, one from Italy, four from Japan, one from Singapore and three from the United States, and we accepted eight papers and rejected two.

Taschenbuch. Zustand: Neu. Neuware - Ischemic colitis is becoming increasingly one of the most important conditions involving the colon. This is due to a combination of multiple factors: (1) increasing age of the world population due to improved public health conditions and advances in medicine; (2) diagnostic advances in recognizing the condition; and, (3) education of physicians who suspect the disease in elderly individuals with colonic symptoms. The disease is a great masquerader of other conditions and can be mistaken for ulcerative colitis, Crohn's disease or almost any other inflammatory disease of the large bowel. It can have shallow ulcers, deep ulcers, filiform polyps, and pseudomembrane. It can produce fistulae or toxic megacolon. The thumb printing and other acute findings are not always seen and the site of involvement may be atypical. It is therefore so important to have a book dealing with this condition extensively and in detail. This scholarly presentation based on large clinical experience significantly contributes to the knowledge of this important disease that will assume even more importance as other conditions involving the colon are successfully treated. As physicians, radiologists and even pathologists have difficulty in diagnosing this condition that appears under multiple guises the information contained here should be invaluable. Alexander R. Margulis, M. D. March 1984, San Francisco PREFACE First of all, I would like to congratulate the authors on their successful publication of this monograph with many diagnostic radiographs of new touch taken by the modern technique.

Taschenbuch. Zustand: Neu. Neuware - This volume gathers the invited talks of the XIII International Work shop on Condensed Matter Theories which took place in Campos do Jordao near Sao Paulo, Brazil, August 6-12, 1989. It contains contributions in a wide variety of fields including neutral quantum and classical fluids, electronic systems, composite materials, plasmas, atoms, molecules and nuclei, and as this year's workshop reflected the natural preoccupation in materials science with its spectacular prospect for mankind, room tempera ture super-conductivity. All topics are treated from a common viewpoint: that of many-body physics, whether theoretical or simu1ational. Since the very first workshop, held at the prestigious Instituto de Fisica Teorica in Sao Paulo, and organized by the same organizer of the 1989 workshop, Professor Valdir Casaca Aguilera-Navarro, the meeting has taken place annually six times in Latin America, four in Europe and three in the United States. Its principal objective has been to innitiate and nurture collaborative research networks of scientists interested in the IDultidisciplinary aspects of many-body theory applied to problems in con densed-matter physics. Financial as well as moral support is gratefully appreciated by all: of the CLAF in Rio, the CNPq in Brasilia, the FAPESP and the FUNDUNESP in Sao Paulo, and the U.S. Army Research Office in Durham, NC, USA.

Taschenbuch. Zustand: Neu. Neuware - The International Astronautical Federation is the only professional society in the field of aerospace engineering and Sciences which brings together specialists of all countries interested in the exploration and peaceful exploitation of space. At its annual Congresses a large number of invited and/or carefully selected con tributed papers are presented which cover a wide variety of topics and are distributed over a number of sessions, each one being organized by two leading scientists who later chair the session itself. Each year the selection of specific topics to be dealt with. is dictated either by significant new progress achieved in some sectors or by new developments and trends which are liable to influence substantially the objectives toward which space research and/or application of space technology will be oriented in the immediate future. A second rigorous screening, performed with the help of the Session Chairmen and carried out according to the same criteria identifies finally the papers which are published in the Proceedings. The outcome of all this is reliable and authoritative information as to the actual status and future trends of space activities, both from the research point of view and from the point of view of u~ilization and/or application.

Taschenbuch. Zustand: Neu. Neuware - The Drugs Handbook 2012-2013 is a reader-friendly text perfect for nursing, health and prescribing courses. Fully updated, it is a concise guide to the mechanism of action, therapeutic indications and chief unwanted effects of medicines available in the United Kingdom, including registered herbal medicines.

Taschenbuch. Zustand: Neu. Neuware - Living with serious illness can have profound emotional effects both on patients themselves and on those close to them. With clarity and compassion, this text explores the difficulties and dilemmas those who are ill and their families face, offering specific guidelines for the professionals who work with them.Building on its successful first edition, this text draws on recent developments in research and clinical practice in providing a theoretical and practical framework for working with illness. Thoroughly revised in its second edition, this book:. Features new chapters on the cultural constructs of illness, working with migrant families, illness in later life, death and palliative care and supervision. Explores issues of working with diversity, covering gender, class, race and sexuality. Discusses the impact of working with those facing serious illness on health care professionals, offering strategies for reducing the risks of burnout, compassion fatigue and secondary traumatisation Written by a recognized expert in the field, this innovative and challenging book provides essential insights for professionals working or training to work with those facing illness and death, including doctors, nurses, counsellors, psychologists, psychotherapists and social workers.

Taschenbuch. Zustand: Neu. Neuware - Overactive Bladder in Clinical Practice provides a timely and comprehensive update on the overactive bladder (OAB) syndrome. The symptoms of urgency, with or without urge incontinence, usually with frequency or nocturia, now defined as the overactive bladder syndrome, have become a hot topic in urology, gynecology and urogynecology. Epidemiological data show very high disease prevalence (19%), particularly when compared with other chronic conditions such as diabetes (2%) and asthma (7%). OAB symptoms impact severely on patient's quality of life, causing significant impairment of patient vitality and limiting their physical role, similar to diabetes. The OAB syndrome involves all age groups, both sexes and is frequently found in neurogenic patients. This book will cover all aspects of OAB epidemiology, economics, pathophysiology, conservative, pharmaceutical and surgical and will be invaluable reading for residents and trainees in urology, gynecology and urogynecology.

Taschenbuch. Zustand: Neu. Neuware - That residues of pesticide and other contaminants in the total environ ment are of concern to everyone everywhere is attested by the reception accorded previous volumes of 'Residue Reviews' and by the gratifying enthusiasm, sincerity, and efforts shown by all the individuals from whom manuscripts have been solicited. Despite much propaganda to the con trary, there can never be any serious question that pest-control chemicals and food-additive chemicals are essential to adequate food production, manufacture, marketing, and storage, yet without continuing surveillance and intelligent control some of those that persist in our foodstuffs could at times conceivably endanger the public health. Ensuring safety-in-use of these many chemicals is a dynamic challenge, for established ones are continually being displaced by newly developed ones more acceptable to food technologists, pharmacologists, toxicologists, and changing pest control requirements in progressive food-producing economies. These matters are of gennine concern to increasing numbers of gov ernmental agencies and legislative bodies around the world, for some of these chemicals have resulted in a few mishaps from improper use. Ade quate safety-in-use evaluations of any of these chemicals persisting into our foodstuffs are not simple matters, and they incorporate the considered judgments of many individuals highly trained in a variety of complex biological, chemical, food technological, medical, pharmacological, and toxicological disciplines.

Taschenbuch. Zustand: Neu. Neuware - In this study we are concerned with Vibration Theory and the Problem of Dynamics during the half century that followed the publication of Newton's Principia. The relationship that existed between these subject!! is obscured in retrospection for it is now almost impossible not to view (linear) Vibration Theory as linearized Dynamics. But during the half century in question a theory of Dynamics did not exist; while Vibration Theory comprised a good deal of acoustical information, posed definite problems and obtained specific results. In fact, it was through problems posed by Vibration Theory that a general theory of Dynamics was motivated and discovered. Believing that the emergence of Dynamics is a critically important link in the history of mathematical science, we present this study with the primary goal of providing a guide to the relevant works in the aforemen tioned period. We try above all to make the contents of the works readily accessible and we try to make clear the historical connections among many of the pertinent ideas, especially those pertaining to Dynamics in many degrees of freedom. But along the way we discuss other ideas on emerging subjects such as Calculus, Linear Analysis, Differential Equations, Special Functions, and Elasticity Theory, with which Vibration Theory is deeply interwound. Many of these ideas are elementary but they appear in a surprising context: For example the eigenvalue problem does not arise in the context of special solutions to linear problems-it appears as a condition for isochronous vibrations.

Taschenbuch. Zustand: Neu. Neuware - In 1979 the International Rel'iel1' of Education celebrated its twenty-fifth anniversary. This book which now reproduces the two Jubilee issues of that Review has been published for a number of reasons. One is the importance of the topics dealt with. The last twenty-five years have seen unprecedented developments in education right across the world, in industrialised countries no less than in those which are still approaching that phase. From time to time it is essential to look back over the past and take stock of how the present situation has come about, to disentangle the trends and sort out from the welter of ideas those which turned out to be non-starters, those which died in their tracks, and those which came to stay. This is only possible after a certain passage of time has set events in proportion and in perspective. The twenty-five years which have elapsed since the IRE was started ten years after the ending of World War II would seem to be just long enough to make this possible, though when the IRE celebrates its fiftieth Jubilee in the year 2004 some of the trends which now seem so definite may themselves have died away to be replaced by others which can now be only dimly conceived. Another reason for this publication is the quality and standing in the world of education and scholarship of the two editors and their contributors.

Taschenbuch. Zustand: Neu. Neuware - That residues of pesticide and other contaminants in the total environ ment are of concern to everyone everywhere is attested by the reception accorded previous volumes of 'Residue Reviews' and by the gratifying enthusiasm, sincerity, and efforts shown by all the individuals from whom manuscripts have been solicited. Despite much propaganda to the con trary, there can never be any serious question that pest-control chemicals and food-additive chemicals are essential to adequate food production, manufacture, marketing, and storage, yet without continuing surveillance and intelligent control some of those that persist in our foodstuffs could at times conceivably endanger the public health. Ensuring safety-in-use of these many chemicals is a dynamic challenge, for established ones are continually being displaced by newly developed ones more acceptable to food technologists, pharmacologists, toxicologists, and changing pest control requirements in progressive food-producing economies. These matters are of genuine concern to increasing numbers of gov ernmental agencies and legislative bodies around the world, for some of these chemicals have resulted in a few mishaps from improper use. Ade quate safety-in-use evaluations of any of these chemicals persisting into our foodstuffs are not simple matters, and they incorporate the considered judgments of many individuals highly trained in a variety of complex biological, chemical, food technological, medical, pharmacological, and toxicological disciplines.

Taschenbuch. Zustand: Neu. Neuware - That residues of pesticide and other contaminants in the total environment are of concern to everyone everywhere is attested by the reception accorded previous volumes of 'Residue Reviews' and by the gratifying enthusiasm, sincerity, and efforts shown by all the in dividuals from whom manuscripts have been solicited. Despite much propaganda to the contrary, there can never be any serious question that pest-control chemicals and food-additive chemicals are essential to adequate food production, manufacture, marketing, and storage, yet without continuing surveillance and intelligent control some of those that persist in our foodstuffs could at times conceivably endanger the public health. Ensuring safety-in-use of these many chemicals is a dynamic challenge, for established ones are continually being dis placed by newly developed ones more acceptable to food tech nologists, pharmacologists, toxicologists, and changing pest-control requirements in progressive food-producing economies. These matters are of genuine concern to increasing numbers of governmental agencies and legislative bodies around the world, for some of these chemicals have resulted in a few mishaps from improper use. Adequate safety-in-use evaluations of any of these chemicals per sisting into our foodstuffs are not simple matters, and they incorporate the considered judgments of many individuals highly trained in a variety of complex biological, chemical, food technological, medical, pharmacological, and toxicologial disciplines.

Taschenbuch. Zustand: Neu. Neuware - 'Sumithion' is the tradename owned by Sumitomo Chemical Co., Ltd., Japan, and given to O,O-dimethyl O-(3-methyl-4-nitrophenyl) phos phorothioate while its generic name registered at ISO and BSI is 'feni trothion.' It is an organophosphorous insecticide having a broad range of insecti cidal spectrum comparable to that of methyl parathion, and its toxicity to mammals and fish is low enough to make its handling of less concern. In 1959 the pesticide research group of Sumitomo Chemical Co., Ltd. was successful in synthesizing Sumithion, which had been code-numbered S-l102-A. Since then, the pesticide staffs of the company have been using their constant efforts in evaluation and practical development of the insecticide in various fields of application under different conditions of the world. Today, Sumithion is an insecticide most extensively used in Japan, being indispensable for field crops, industrial crops, and forestry protec tion besides public health purposes. In many other countries of the world, usage of Sumithion is now so extended that it has come to be known as a typical organophosphorus insecticide together with methyl parathion and malathion. Much of the information accumulated on Sumithion is here published by the members of Sumitomo engaged in the research and development of the compound.

Taschenbuch. Zustand: Neu. Neuware - In recent years, the techniques of electron microscopy have developed so widely and rapidly that they now cover the fields of research once the unique ll:panage of sister research techniques such as biochemistry, physiology, immunology, X-ray diffraction, etc. It is now possible to reach molecular and submolecular levels, making this technique indispensable in every type of research. Electron microscopy alone often provides enough information to solve given problems. In the field of the connective tissue matrix, knowledge of the molecular structure of collagen, pro teoglycans and elastin and their interaction has been to a large extent elucidated by electron microscopy. The field over which electron microscopy ranges in the investigation of the connective tissue matrix is so wide that the aim of this volume is to collect the main ultrastructural acquisitions disseminated in various journals and monographs in one book. The intent ofthis volume is to: (a) integrate different and new microscopic methods and review the results of such an integrative approach; (b) present a comprehensive ultrastructural account of selected aspects of the field; (c) point out gaps or controversial topics in our knowledge; (d) outline pertinent future research and expansion of the subject.

Taschenbuch. Zustand: Neu. Neuware - Worldwide concern in scientific, industrial, and governmental com munities over traces of toxic chemicals in foodstuffs and in both abiotic and biotic environments has justified the present triumvirate of specialized publications in this field: comprehensive reviews, rapidly published progress reports, and archival documentations. These three publications are integrated and scheduled to provide in international communication the coherency essential for nonduplicative and current progress in a field as dynamic and complex as environmental contamination and toxicology. Until now there has been no journal or other publication series reserved exclusively for the diversified literature on 'toxic' chemicals in our foods, our feeds, our geographical surroundings, our domestic animals, our wild life, and ourselves. Around the world immense efforts and many talents have been mobilized to technical and other evaluations of natures, locales, magnitudes, fates, and toxicology of the persisting residues of these chemicals loosed upon the world. Among the sequelae of this broad new emphasis has been an inescapable need for an articulated set of authorita tive publications where one could expect to find the latest important world literature produced by this emerging area of science together with documentation of pertinent ancillary legislation.

Taschenbuch. Zustand: Neu. Neuware - Worldwide concern in scientific, industrial, and governmental com munities over traces of toxic chemicals in foodstuffs and in both abiotic and biotic environments has justified the present triumvirate of specialized publications in this field: comprehensive reviews, rapidly published progress reports, and archival documentations. These three publications are integrated and scheduled to provide in international communication the coherency essential for nonduplicative and current progress in a field as dynamic and complex as environmental contami nation and toxicology. Until now there has been no journal or other publication series reserved exclUSively for the diversified literature on 'toxic' chemicals in our foods, our feeds, our geographical surround ings, our domestic animals, our wildlife, and ourselves. Around the world immense efforts and many talents have been mobilized to tech nical and other evaluations of natures, locales, magnitudes, fates, and toxicology of the persisting residues of these chemicals loosed upon the world. Among the sequelae of this broad new emphasis has been an inescapable need for an articulated set of authoritative publications where one could expect to find the latest important world literature produced by this emerging area of science together with documenta tion of pertinent ancillary legislation.

Taschenbuch. Zustand: Neu. Neuware - That residues of pesticide and other contaminants in the total environ ment are of concern to everyone everywhere is attested by the reception accorded previous volumes of 'Residue Reviews' and by the gratifying enthusiasm, sincerity, and efforts shown by all the individuals from whom manuscripts have been solicited. Despite much propaganda to the con trary, there can never be any serious question that pest-control chemicals and food-additive chemicals are essential to adequate food production, manufacture, marketing, and storage, yet without continuing surveillance and intelligent control some of those that persist in our foodstuffs could at times conceivably endanger the public health. Ensuring safety-in-use of these many chemicals is a dynamic challenge, for established ones are continually being displaced by newly developed ones more acceptable to food technologists, pharmacologists, tOxicologists, and changing pest control requirements in progressive food-producing economies. These matters arc of genuine concern to increasing numbers of gov ernmental agencies and legislative bodies around the world, for some of these chemicals have resulted in a few mishaps from improper use. Ade quate safety-in-use evaluations of any of these chemicals persisting into our foodstuffs are not simple matters, and they incorporate the considered judgments of many individuals highly trained in a variety of complex biological, chemical, food technological, medical, pharmacological, and toxicological disciplines.

Taschenbuch. Zustand: Neu. Neuware - For some time now, the study of cognitive development has been far and away the most active discipline within developmental psychology. Although there would be much disagreement as to the exact proportion of papers published in develop mental journals that could be considered cognitive, 50% seems like a conservative estimate. Hence, a series of scholarly books devoted to work in cognitive devel opment is especially appropriate at this time. The Springer Series in Cognitive Development contains two basic types of books, namely, edited collections of original chapters by several authors, and original volumes written by one author or a small group of authors. The flagship for the Springer Series is a serial publication of the 'advances' type, carrying the subtitle Progress in Cognitive Development Research. Each volume in the Progress sequence is strongly thematic, in that it is limited to some well-defined domain of cognitive developmental research (e.g., logical and mathematical development, development of learning). All Progress volumes will be edited collections. Editors of such collections, upon consultation with the Series Editor, may elect to have their books published either as contributions to the Progress sequence or as separate volumes. All books written by one author or a small group of authors are being published as separate volumes within the series.

Taschenbuch. Zustand: Neu. Neuware - The rapid and continuous upsurge of interesting data in the subject of tumor immunology necessitates the publication of an annual series to furnish the updated materials to the students, researchers, and clinicians in this rapidly advancing field. Concepts and methodologies are ever changing. Also, current research in tumor immunology promises to offer breakthroughs in the future. Important is the need to communicate to the right people the exact role of immunodiagnostic methods and immunological intervention in cancer preven tion and treatment. The role of immunotherapy in combination with conven tional modalities of treatment needs to be understood in its proper perspective. Oncogene, interferon, lymphokines, monoclonal antibodies, natural killer cells, platelet-mediated cytotoxicity of antibody-coated target cells, suppressor cells, platelet-derived factors, plasma-blocking factors, control of suppressor cell func tion, abrogation of plasma-blocking factors, and so forth, are some of the areas that are continually advancing. Progress in these areas will have implication in cancer therapy. Further, it is already understood that if immunocompetence of the host can be maintained at a reasonably good level, there exists the potential to increase the therapeutic indexes of conventional modalities of treatment. This series will attempt to present updated information in all these areas based on con tributed and solicited articles.

Taschenbuch. Zustand: Neu. Neuware - We are again proud to present an excellent volume of contemporary topics in NMR and EPR to the biological community. The philosophy behind the volume and the presentation of each chapter remains at the high level reflected in our earlier volumes: to be current, pedagogical, and critical. The first chapters, as always, address a subject related to in-vivo biology. Gabby Elgavish addresses NMR spectroscopy of the intact heart. lain Campbell and colleagues present a state-of-the-art description of NMR methods for probing enzyme kinetics in intact cells and tissues. Klaus Mobius and Wolfgang Lubitz have produced a thorough review of the principles and applications of ENDOR spectroscopy in photobiology and biochemistry including discussions of liquid and solid state ENDOR as well as CIDEP-enhanced ENDOR. The final chapter by Hans Vogel and Sture Forsen addresses a contemporary problem in inorganic biochemistry, namely cation binding to calcium binding proteins. We are pleased to announce that a special forthcoming volume will be devoted entirely to the subject of 'Spin Labeling: Theory and Applications (3rd compendium).' A substantial degree of progress has occurred in this important area of ESR in biology since the last treatise on the subject in 1979. Lastly, we acknowledge our colleagues in the field who continue to support this excellent series both as subscribers and contributors. We pledge to continue servicing the community as long as the need exists.

Taschenbuch. Zustand: Neu. Neuware - There is much evidence to suggest that prostaglandins may have a physiological role to play in the control of thyroid gland metabolism, although the precise nature of this role remains to be defined. Prostaglandins have been found in normal thyroid tissue, and there is evidence of increased levels in some, but not all, cases of medullary carcinoma of the thyroid. which may account for the associated diarrhea. Exogenous prostaglandins, like TSH, bind to thyroid plasma mem branes, stimulate the adenylate cyclase-cyclic AMP system, thyroid hormone secretion, iodide organification, colloid droplet formation, glucose oxidation, and 32p incorporation into phospholipids. Prosta glandins of the E series are the most potent, although their maximal effects are generally less than the maximal effects of TSH. The interrelationships existing between TSH and prostaglandins have been the subject of intensive investigation, but as yet no one uni fying concept has emerged. TSH and prostaglandins have been shown to occupy different receptors on the thyroid plasma membrane. Al though TSH can increase intracellular prostaglandin levels, probably as a result of increased synthesis, prostaglandins do not appear to be essential intermediates in TSH action on adenylate cyclase. The pos sibility that prostaglandins are part of a negative feedback system con trolling TSH action is, as yet, a tentative hypothesis, and further work will be required to unravel the interrelationships between these sub stances that now appear to be far more complex than has been envisaged thus far.

Taschenbuch. Zustand: Neu. Neuware - The use of ultrasound for various diagnostic techniques in medicine continues to increase in popularity and complexity. It seems possible that the prediction of the National Science Foun dation that ultrasonic techniques may be used as frequently as X-ray techniques by the end of the decade may indeed be fulfilled. The annual scientific meeting of the American Institute of Ultra sound in Medicine is the only meeting held regularly on the North American continent and devoted solely to the diagnostic use of ultrasound. Under these circumstances it is not surprising to find that both the attendance at these meetings and the number of papers submitted for presentation, are increasing markedly each year. The papers presented at these meetings probably reflect the 'state-of-the-Art' reasonably accurately. The Proceedings of these annual meetings are therefore a valuable record of the current state of ultrasonic diagnostic techniques in the U.S.A. Even though it is not possible to print in extenso every paper presented at the meeting, an attempt has been made with this volume, by increasing the length of the papers printed in abstract form, to enable the reader to obtain an overall view of current developments and research on this continent in all fields of ultrasonic medical diagnostic technology. Speed of publication is essential if this volume is to contain current information.