springer basel springer basel nov 2013 (8 Ergebnisse)

Buch. Zustand: Neu. Neuware -The book deals with continuous piecewise linear differential systems in the plane with three pieces separated by a pair of parallel straight lines. Moreover, these differential systems are symmetric with respect to the origin of coordinates. This class of systems driven by concrete applications is of interest in engineering, in particular in control theory and the design of electric circuits. By studying these particular differential systems we will introduce the basic tools of the qualitative theory of ordinary differential equations, which allow us to describe the global dynamics of these systems including the infinity. The behavior of their solutions, their parametric stability or instability and their bifurcations are described. The book is very appropriate for a first course in the qualitative theory of differential equations or dynamical systems, mainly forengineers, mathematicians, andphysicists.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 304 pp. Englisch.

Buch. Zustand: Neu. Neuware -This volume comprises the proceedings of the Conference on Operator Theory and its Applications held in Gothenburg, Sweden, April 26-29, 2011. The conference was held in honour of Professor Victor Shulman on the occasion of his 65th birthday. The papers included in the volume covera large variety of topics, among them the theory of operator ideals, linear preservers, C\*-algebras, invariant subspaces, non-commutative harmonic analysis, and quantum groups, andreflect recent developments in these areas. The book consists of bothoriginal research papers and high quality survey articles, allofwhich werecarefully refereed. ¿Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 304 pp. Englisch.

Buch. Zustand: Neu. Neuware -Chronic obstructive pulmonary disease (COPD) is a multi-component condition that results in increasingly limited airflow, usually associated with an abnormal inflammatory response of the lung. It constitutes a major public health burden worldwide, while only very few effective therapies are available.This book provides a comprehensive overview of the development of Onbrez Breezhaler, a newly approved once-daily inhaled ¿2 agonist for the treatment of COPD. It reviews the current pharmacotherapy for COPD and discusses topics such as the chemical design and the pre-clinical pharmacology of the molecule, the early clinical development, the INHANCE study (which provides a successful example of the use of an adaptive design in the confirmatory setting) and the Phase III clinical efficacy study, as well as the history and performance of the Breezhaler device. Finally, a list of emerging targets is included that could well offer future treatment options for COPD.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 156 pp. Englisch.

Buch. Zustand: Neu. Neuware -This book contains a collection of research articles and surveys on recent developments on operator theory as well as its applications covered in the IWOTA 2011 conference held at Sevilla University in the summer of 2011. The topics includespectral theory, differential operators, integral operators, composition operators, Toeplitz operators, andmore.The book also presents a largenumber of techniques in operator theory.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 560 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -InhaltsangabePart I: Stochastic Analysis.- Dirichlet forms for Poisson measures and Lévy processes: the lent particle method.- Backward stochastic difference equations with finite states.- On a forward-backward stochastic system associated to the Burgers equation.- Quantifying model uncertainties in complex systems.- On the estimate for commutators in DiPerna-Lions theory.- Approximation theorem for stochastic differential equations driven by G-Brownian motion.- Stochastic flows for nonlinear SPDEs driven by linear multiplicative space-time white noises.- Optimal stopping problem associated with jump-diffusion processes.- A review of recent results on approximation of solutions of stochastic differential equations.- Strong consistency of Bayesian estimator under discrete observations and unknown transition density.- Stability of a nonlinear equation related to a spatially-inhomogeneous branching process.- Exponentially stable stationary solutions for delay stochastic evolution equations.- Robust stochastic control and equivalent martingale measures.- Multivalued stochastic differential questions driven by point processes.- Logarithmic derivatives of densities for jump processes.- Part II: Financial Applications.- Convertible bonds in a defaultable diffusion model.- A geometric approach to option pricing with transaction costs in discrete models.- Completeness and hedging in a Lévy bond market.- Asymptotically efficient discrete hedging.- Estimating joint default probability by efficient importance sampling with applications from bottom up.- Market models of forward CDS spreads.- Optimal threshold dividend strategies under the compound Poisson model with regime switching.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 440 pp. Englisch.

Buch. Zustand: Neu. Neuware -This book summarizes the state-of-the art in the development of T cell-based in vitro assays, which offer useful tools for hazard identification, risk assessment and improvement of diagnostics. It will be of interest to scientists, the chemical and pharmaceutical industry, and regulators involved in the replacement of animal testing methods.The identification of hazardous chemicals and drugs is essential to ensuring human health. The ban on animal testing for the cosmetics industry since 2009 and international efforts to reduce and replace animal testing in research and immunotoxicology call for alternative in vitro methods. The most specific immune response to chemicals and drugs that cause allergic contact dermatitis, respiratory disease and adverse drug reactions is the highly antigen-specific T lymphocyte response. Therefore the use of T cells as tools for identifying contact allergens and drugs that may cause health problems is of great interest.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 192 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -This book is an introduction to the subject of mean curvature flow of hypersurfaces with special emphasis on the analysis of singularities. This flow occurs in the description of the evolution of numerous physical models where the energy is given by the area of the interfaces. These notes provide a detailed discussion of the classical parametric approach (mainly developed by R. Hamilton and G. Huisken). They are well suited for a course at PhD/PostDoc level and can be useful for any researcher interested in a solid introduction to the technical issues of the field. All the proofs are carefully written, often simplified, and contain several comments. Moreover, the author revisited and organized a large amount of material scattered around in literature in the last 25 years.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 180 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -The inflammasome was first described in 2002 as a molecular complex activating proinflammatory caspases and therefore regulating the maturation and biological activities of cytokines such as IL-1¿ and IL-18. This finding was substantiated by the identification of several mutations in the cias1 gene, encoding the human NLRP3 protein, responsible for several autoinflammatory disorders such as the Muckle Wells syndrome. Since, the interest for this complex has constantly increased and several inflammasome complexes with different specificities have been described. These inflammasomes sense a wide variety of pathogens and danger signals and are key players in the inflammatory response. With the contributions of leading international experts in the field, this book provides an extensive overview of the current knowledge of inflammasome biology and their role in health and disease.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 240 pp. Englisch.