rsc publishing sep 2010 (4 Ergebnisse)

Taschenbuch. Zustand: Neu. Neuware - Over the last 150 years, the Public Analyst profession has hidden its light under a bushel, with the notable exception of Fredrick Accum, one of the first Public Analysts who published the names and addresses of food adulterers, this group of chemists has quietly protected the public from food fraud and adulteration. Using their forensic skills to find traces of poison and other deleterious materials in our food and guiding the Courts and legal profession through complex scientific evidence, it has undersold itself to the public. It is time to tell their story with this collection of memoirs from many practising and retired Public Analysts. Their accounts of samples submitted to them, how they analysed them, and the tales that unfolded, make for a fascinating insight into the field. This is a timely publication, as funding for this area continues to fall, to the concern of many not just in the UK but throughout Europe. Yet, whilst food adulteration may not be as rife as it was 150 years ago, food fraud and adulteration is now on a global scale with improved communications, the fear of adulteration is probably larger than ever. This funding position does not sit well alongside levels of public interest that have never been higher in food, science in general, and forensic science. And yet research is still needed to find future strategies to maintain a vital service to protect the public and it is important to raise the profile of the role of the Public Analyst, now more than ever, This book, which is not intended as a text book but as a light read, will achieve this aim while simply telling the stories of a collection of Public Analysts, things they have found in food and other materials and their memoirs and anecdotes. It will appeal to those who watch programmes such as Crime Scene Investigation and anyone with an interest in forensic science and science in general.

Buch. Zustand: Neu. Neuware - In September 2009, a meeting was held in Palm Cove, Australia, which brought together the world experts in the Maillard or 'browning' reaction. This reaction causes the browning of foods when they are heated and in chocolate, caramel and beer, this reaction is appetizing, contributing to aroma, taste and texture. But when these products accumulate in the body, this same process contributes to disease and ageing. The book is the proceedings of that meeting, held in response to a growing recognition of the role reactive carbonyl compounds play in food technology, nutrition and tissue ageing in biology and medicine. Reactive carbonyls now touch every aspect of food science, biology and medicine. Efforts to counteract the damage caused by these products are gaining acceptance as a basis for novel therapeutic approaches, and the fields of food technology, ageing and preventive medicine are experiencing an upsurge of interest in strategies to minimize the unwanted effects of the Maillard reaction. The meeting also fostered a balanced approach to understanding both the advantageous and deleterious properties of carbonyl compounds and their end products in food science, technology and medicine. The major audience of this book is the large body of scientists and worldwide industries with an interest in the Maillard reaction in foods and biology and medicine, with both basic and applied researchers and industry representatives from diverse fields, who have interests in: \* Chemistry of the Maillard Reaction \* Biology and the Maillard Reaction \* Enzymology, Receptors and Signal Transduction \* Bioinformatics and Systems Biology \* Physiology, Disease and Therapeutics \* Food Science and Nutrition and the Maillard Reaction.

Buch. Zustand: Neu. Neuware - Accounts in Drug Discovery describes recent case studies in medicinal chemistry with a particular emphasis on how the inevitable problems that arise during any project can be surmounted or overcome. The Editors cover a wide range of therapeutic areas and medicinal chemistry strategies, including lead optimization starting from high-throughput screening 'hits' as well as rational, structure-based design. The chapters include 'follow-ons' and 'next generation' compounds that aim to improve upon first-generation agents. This volume surveys the range of challenges commonly faced by medicinal chemistry researchers, including the optimization of metabolism and pharmacokinetics, toxicology, pharmaceutics and pharmacology, including proof-of-concept in the clinic for novel biological targets. The case studies include medicinal chemistry stories on recently approved and marketed drugs, but also chronicle 'near-misses', i.e. exemplary compounds that may have proceeded well into the clinic but for various reasons did not result in a successful registration. As the vast majority of projects fail prior to registration, much can be learned from such narratives. By sharing a wide range of drug discovery experiences and information across the community of medicinal chemists in both industry and academia, the Editors believe that these accounts will provide insights into the art of medicinal chemistry as it is currently practiced and will help to serve the needs of active medicinal chemists.

Buch. Zustand: Neu. Neuware - There is increasing recognition that low-cost, high capacity processes for the conversion of biomass into fuels and chemicals are essential for expanding the utilization of carbon neutral processes, reducing dependency on fossil fuel resources, and increasing rural income. While much attention has focused on the use of biomass to produce ethanol via fermentation, high capacity processes are also required for the production of hydrocarbon fuels and chemicals from lignocellulosic biomass. In this context, this book provides an up-to-date overview of the thermochemical methods available for biomass conversion to liquid fuels and chemicals. In addition to traditional conversion technologies such as fast pyrolysis, new developments are considered, including catalytic routes for the production of liquid fuels from carbohydrates and the use of ionic liquids for lignocellulose utilization. Written by a team of international experts this book will be an essential reference for advanced and postgraduate level students, chemical and biological engineers, energy researchers, agricultural and environmental scientists from academia, industry and government.