Rsc publishing sep 2003 (4 Ergebnisse)

Taschenbuch. Zustand: Neu. Neuware - Natural products are compounds that are produced by living systems and the secondary metabolites are those which give particular species their characteristic features. These natural products include polyketides, terpenoids, phenylpropanoids, alkaloids and antibiotics. The study of these natural products has played a major part in the development of organic and medicinal chemistry and we are now starting to understand the important ecological role that these compounds have. The aim of this book is to describe the major features of these compounds and the way in which chemical and physical methods have been used to establish their structures and then to show how these structures can be rationalised in biosynthetic terms. The first chapter describes the classes of natural product, their biological activity and isolation. Subsequent chapters attempt to link chemical and spectroscopic strategies in structure elucidation, contrasting the classical chemical strategies that were used in the past with modern spectroscopic methods. The final chapter describes the biosynthesis of natural products. The elucidation of the structures of natural products brings together many elements taught in courses on functional group chemistry, stereochemistry and elementary spectroscopy. This book will therefore be welcomed by lecturers and students of second-year chemistry courses. Ideal for the needs of undergraduate chemistry students, Tutorial Chemistry Texts is a major series consisting of short, single topic or modular texts concentrating on the fundamental areas of chemistry taught in undergraduate science courses. Each book provides a concise account of the basic principles underlying a given subject, embodying an independent-learning philosophy and including worked examples.…

Taschenbuch. Zustand: Neu. Neuware - Introducing the application of free energy correlations to elucidating the mechanisms of organic and bio-organic reactions, this book provides a new and illuminating way of approaching a potentially complex topic. The idea of how free energy correlations derive from polar substituent change is introduced, and common pitfalls encountered in the application of free energy relationships are described, along with the use of these anomalies in mechanistic studies. The concept of effective charge is described in detail, with examples of its application. Throughout, worked answers are provided for the problems posed. Databases of parameters, an extensive bibliography and comprehensive lists of further reading are also included. The text provides an invaluable source of information to senior undergraduates, postgraduates and to industrial researchers with an interest in mechanistic studies. It is the first such book in more than thirty years.…

Taschenbuch. Zustand: Neu. Neuware - Statistical methods are essential tools for analysts, particularly those working in Quality Control Laboratories. This book provides a sound introduction to their use in analytical chemistry, without requiring a strong mathematical background. It emphasises simple graphical methods of data analysis, such as control charts, which are also a fundamental requirement in laboratory accreditation. A large part of the book is concerned with the design and analysis of laboratory experiments, including sample size determination. Practical case studies and many real databases from both QC laboratories and the research literature, are used to illustrate the ideas in action.The aim of Statistics for the Quality Control Chemistry Laboratory is to give the reader a strong grasp of the concept of statistical variation in laboratory data and of the value of simple statistical ideas ad methods in thinking about and manipulation such data, It will be invaluable to analysts working in QC laboratories in industry, hospitals and public health, and will also be welcomed as a textbook for aspiring analysts in colleges and universities.…

Buch. Zustand: Neu. Neuware - Nutritional Aspects of Bone Health provides an in-depth review of the role of diet in the development and maintenance of bone health throughout the lifecycle, and prevention of osteoporosis in later life. The book is multi-authored by the world's leading researchers in this area, who have come together to formulate the first ever textbook on nutritional aspects of bone health, and includes the current and cutting edge science underpinning the prevention of bone disease. The book is structured such that, in the first section, an overview is provided on what is meant by the terms bone health and osteoporosis and includes key areas such as epidemiology, genetics and the impact of non-nutritional exogenous factors influencing the skeleton. The second section details the established nutritional factors affecting bone health, namely calcium and vitamin D. Section three focuses on the role of macronutrients and macrominerals in bone health, namely protein, phosphorus, sodium and potassium, including the criticality of acid-base homeostasis to skeletal integrity. Section four addresses the effects of microminerals, trace elements, vitamin K, vitamin A and isoflavones on bone. Section five focuses attention on key issues connected with the influence of diet and anorexia and bulimia on bone health including nutrition and bone growth; nutrient: gene interactions; nutrient: drug interactions; and the final section discusses the effect of diet on reduction of fracture risk; the cost-effectiveness of nutritional supplements; and nutritional strategies for prevention and treatment of osteoporosis. The book is targeted at a number of key audiences. Whilst there is a focus on the academic research world and those principally involved in education, at both undergraduate and postgraduate levels, the book will also be of considerable interest to those participating in the treatment and prevention of osteoporosis, namely those working in the medical and health promotion fields. Furthermore, Nutritional Aspects of Bone Health will be of particular interest to the food industry as the popularity of foods designed to target specific health issues increases, and nutritional therapy has a critical role to play in this major public health problem.…