rsc publishing aug 2019 (11 Ergebnisse)

Buch. Zustand: Neu. Neuware - Energy is an important area of contemporary research, with clear societal benefits. It is a fast-developing and application-driven research area, with chemistry leading the discovery of new solids, which are then studied by physicists and materials scientists.

Buch. Zustand: Neu. Neuware - The development of novel materials whose structure, properties or function are inspired by nature or living matter is a wide and dynamically evolving field. There is virtually no field of scientific endeavour that has not felt the touch of the 'bioinspired' ethos.

Buch. Zustand: Neu. Neuware - Forensic analysis relates to the development of analytical methods from laboratory applications to in-field and in situ applications to resolve criminal cases. There has been a rapid expansion in the past few years in this area, which has led to an increase in the output of literature. This is the first book that brings together the understanding of the analytical techniques and how these influence the outcome of a forensic investigation.

Buch. Zustand: Neu. Neuware - Nanoparticles have numerous biomedical applications including drug delivery, bone implants and imaging. A protein corona is formed when proteins existing in a biological system cover the nanoparticle surface. The formation of a nanoparticle-protein corona, changes the behaviour of the nanoparticle, resulting in new biological characteristics and influencing the circulation lifetime, accumulation, toxicity, cellular uptake and agglomeration.

Buch. Zustand: Neu. Neuware - Immunosensors are widely used and are particularly important for fast diagnosis of diseases in remote environments as well as point-of-care devices. In this book, expert scientists are covering a selection of high quality representative examples from the past five years explaining how this area has developed. It is a compilation of recent advances in several areas of immunosensors for multiple target analysis using laboratory based or point-of-care set-up, for example graphene-, ISFET- and nanostructure-based immunosensors, electrochemical magneto immunosensors and nanoimprinted immunosensors.

Buch. Zustand: Neu. Neuware - Since the introduction of FT-NMR spectroscopy around five decades ago, NMR has achieved significant advances in hardware and methodologies, accompanied with the enhancement of spectral resolution and signal sensitivity. Rapid developments in the polymers field mean that accurate and quantitative characterization of polymer structures and dynamics is the keystone for precisely regulating and controlling the physical and chemical properties of the polymer. This book specifically focuses on NMR investigation of complex polymers for the polymer community as well as NMR spectroscopists, and will push the development of both fields. It covers the latest advances, for example high field DNP and ultrafast MAS methodologies, and show how these novel NMR methods characterize various synthetic and natural polymers.

Buch. Zustand: Neu. Neuware - Peptide therapy has become a key strategy in innovative drug development, however, one of the potential barriers for the development of novel peptide drugs in the clinic is their deficiencies in clearly defined chemistry, manufacturing and controls (CMC) strategy from clinical development to commercialization. CMC can often become a rate-limiting step due to lack of knowledge and lack of a formal policy or guidelines on CMC for peptide-based drugs. Regulators use a risk-based approach, reviewing applications on a case-by-case basis.Peptide Therapeutics: Strategy and Tactics for Chemistry, Manufacturing, and Controls covers efficient manufacturing of peptide drug substances, a review of the process for submitting applications to the regulatory authority for drug approval, a holistic approach for quality attributes and quality control from a regulatory perspective, emerging analytical tools for the characterisation of impurities, and the assessment of stability.This book is an essential reference work for students and researchers, in both academia and industry, with an interest in learning about CMC, and facilitating development and manufacture of peptide-based drugs.

Buch. Zustand: Neu. Neuware - Photoaging, like other diseases that affect older people disproportionately, is a growing area of research due to increasingly aging populations in many parts of the world. This book will provide a comprehensive account of the field covering topics such as control and structural analysis and the different approaches to utilizing light as a source for materials science. The core chapters focus on the current understanding of the biochemical mechanisms of photoageing and lead on to aspects of photoprotection and photomedicine to provide a complete picture of the current field and a context for the importance of the basic mechanistic understanding. With an international team of renowned contributors, this book is an ideal reference volume for dermatologists, photobiologists, physicians and students.

Buch. Zustand: Neu. Neuware - With the need to combat emerging infectious diseases, research around antimicrobial biomaterials and their applications is booming. This book provides the field with a much-needed fundamental overview of the science, addressing the chemistry of a broad range of biomaterial types, and their applications in the biomedical industry.

Buch. Zustand: Neu. Neuware - Structure determination of molecules contained within unresolved complex mixtures represents an unsolved question that continues to challenge physical and analytical chemistry. Most naturally occurring systems can be characterised as complex mixtures. These can be broadly divided according to the molecular sizes of their constituents, into mixtures of small or large molecules; the focus of this volume is on the former. While large molecules such as biomacromolecules, industrial polymers, or solid matrices are outside of the scope of this volume, the processes that are used in analysing the data originating from these studies may be of interest.

Buch. Zustand: Neu. Neuware - Gaseous ion spectroscopy generally couples mass spectrometry with a class of high-resolution laser spectroscopy, providing a route for studying the intrinsic chemical and physical properties of isolated ions. The isolation of the molecular ion of interest from its native environment is important to decouple the influence of the surroundings from the intrinsic properties. The effect of the environment can then be incrementally re-introduced through studies of sequentially solvated clusters, which allow the interaction with solvent molecules with the ion to be studied on the molecular level.