infinite science publishing (89 Ergebnisse)

Zustand: Good. Most items will be dispatched the same or the next working day. A copy that has been read but remains in clean condition. All of the pages are intact and the cover is intact and the spine may show signs of wear. The book may have minor markings which are not specifically mentioned.

Taschenbuch. Zustand: Neu. Neuware -Magnetic Particle Imaging (MPI) is a novel imaging modality that uses various static and oscillating magnetic fields to image the spatial distribution of superparamagnetic iron oxide nanoparticles (SPIOs) with high sensitivity, no tissue background, and no ionizing radiation. The method exploits the non-linear magnetization behavior of the SPIOs, and has shown great potential to surpass current in vivo imaging modalities in terms of sensitivity, safety, quantitation, and spatio-temporal resolution. MPI is well suited for clinical applications such as angiography, cancer imaging, and inflammation imaging; as well as research applications such as stem cell imaging and small animal imaging. Since the first workshop in 2010, the International Workshop on MPI (IWMPI) has been the premier forum for researchers working in the MPI field. The workshop aims at covering the status and recent developments of both the instrumentation and the tracer material, as they are equally important in designing a well performing MPI system. The main topics presented at the workshop include hardware developments, image reconstruction and systems theory, nanoparticle physics and theory, nanoparticle synthesis, spectroscopy, patient safety, and medical/research applications of MPI.BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt 200 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -In the research of neuronal diseases, a comparison of magnetic resonance imaging (MRI) and histology sections is indispensable. While histology provides information about microscopic structures and chemical composition of brain tissue, in-vivo high-contrast MRI is a powerful tool for detecting pathologic structures in living animals. In clinic practice, the histology-MRI correspondence is often determined visually by experienced neuroscientists. This is a time-consuming and laborious procedure. In this Book an imaging pipeline in described that automatically aligns histology sections to the anatomically corresponding position in the MRI. In order to evaluate the underlying methodology, corresponding anatomical landmarks in MRI and histology were selected by experts. The accuracy achieved by the reconstruction and registration pipeline enables a precise analysis of microstructural features seen in the histology sections and superimposed on the MRI. This in turn is extremely valuable for studying the cellular mechanisms that are responsible for signal changes in MRI.BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt 76 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -Table of Contents ¿ 1. Biomedical Optics: E.g. Flow velocity measurements using Doppler optical coherence tomography; Characterization of a micro machined deformable membrane mirror using optical coherence tomography; Laser Ray Tracing Setup for Measuring the Refractive Index Changes in Bovine Lenses; Optically Monitored Selective Laser Trabeculoplasty; 2. Biochemical Physics: E.g. LED-based Illumination Set-up for In Vitro Photodynamic Therapy; Construction and implementation of a simple stopped-flow apparatus for the investigation of rapid kinetics using confocal fluorescence microscopy; Fluorescence Properties and Cytotoxicity of Nanoparticle-based Ratiometric Fluorescent Thermometer on RPE Cells; 3. Biomedical Engineering: Dispension of a bead suspension into small vessels; Simulation of torque acting on the joint of an exoskeleton for stroke rehabilitation; Determination of Measurement Characteristics of a Sensor for Blood Leakage in Hemodialysis; Checking the usability of a valve system to control a pressure controlled valve from a breathing machine; 4. Safety and Quality: Investigation of the APICA ASCTM access and closure device for the delivery of mitral valve therapies; Technical Reequipment and Restructuring of Endoscopic Department at Demmin Hospital; Developing a procedure to test the compatibility of flexible endoscopes with an Endo-Thermo-Disinfector (ETD); 5. Medical Imaging: Novel Method to Measure Migration of Percutaneous Nerve Evaluation Leads; The measurement of the peak kilovoltage across microfocus X-ray tubes by using K-shell radiation and K-shell absorption; Analyzing the Impact of Different Path Termination Conditions in a Probabilistic Fiber Tracking Algorithm; 6. Signal Processing: Single-trial variability of non-invasively recorded high-frequency somatosensory evoked potentials; Evaluation of a Skin-to-Electrode Impedance Measuring System; Quantitative evaluation of online signal processing for fMRI-based neurofeedback; Receive Chain Noise Matching For Magnetic Particle Imaging; 7. Image Processing: Experimental Evaluation of Different Weighting Schemes in Magnetic Particle Imaging Reconstruction; Comparison and Performance Evaluation of Indoor Localization Algorithms based on an Error Mode for an Optical System; Fully Automated Camera Calibration for X-ray Inspection and Computed Tomography Systems;BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt 240 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -A new tomographic imaging modality called magnetic particle imaging (MPI) has been proposed in 2005. Using the non-linear magnetization curve of specific nanoparticles, a detectable signal proportional to the concentration of these particles can be generated. For medical imaging the tracer material can be injected into the blood system. Due to fast image acquisition, not only morphological, but also functional imaging is possible. The feasibility of medical imaging with this technique could be demonstrated at real time imaging of a beating mouse heart. Spatial encoding is provided by superimposing dedicated external magnetic fields. For the resulting shape of this field a field free line has been proposed. This work presents the implementation of the MPI system with a discretely rotatable and dynamically translatable field free line.BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt 84 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -This Book of Abstracts is a collection of contributions to the first symposium on functional autoantibodies targeting G-protein-coupled receptors (GPCRs) in Lübeck. GPCRs are involved in a variety of physiological and pathophysiological processes. So far, much effort has been made on anti-GPCR drug discovery with a focus on the development of small molecules and monoclonal antibodies for the treatment of cancer, infection, metabolic disorders or inflammatory diseases. Recently, functional autoantibodies against GPCRs were identified in various diseases associated with pathogenesis, uncovering a potential new field of therapeutic intervention. Thus, the aim of this symposium is to combine the current knowledge about the role of GPCRs in different pathologies, their mode of action and state-of-the-art research techniques to identify common fundamental pathways that can be transferred to other disease entities with similar manifestations.BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt 76 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -Magnetic Particle Imaging (MPI) is a recently introduced medical imaging modality that promises high sensitivity, high resolution and real-time ability by imaging the spatial distribution of super-paramagnetic iron-oxide nanoparticles. The reconstruction techniques can be categorized into frequency and x-space reconstruction. In this book, a comparison between both techniques is made based on a simulation study. The x-space reconstruction technique using the Lissajous trajectories is presented for various parameters of an ideal scanner. Furthermore, the deconvolution process for the x-space reconstruction is performed with two techniques, the Tikhonov and the Wiener deconvolution. Frequency reconstruction and x-space reconstruction are compared in terms of different setups regarding the density of the trajectory, gradient strength and sampling frequency for an ideal scanner and a realistic scanner with classical coil geometry. The advantages and disadvantages of both reconstruction techniques are analyzed in detail.BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt 96 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -Magnetic Particle Imaging is a functional imaging technique used to visualize the distribution of superparamagnetic iron oxide nanoparticles by using magnetic fields. These fields are generated by current carrying coils specifically arranged in different scanner topologies. Up to now, the established geometries of a coil have been either circular shaped or rectangular shaped. The aim of this work is to evaluate the application of approximated elliptical coils. Based on the clinical practice, it is conceivable to integrate a circular single-sided scanner, for example, into a patient table. In order to achieve an optimally adapted result to the medical application, a tradeoff between size, field of view and patient access must be made. The new coil geometry is designed to increase the field of view, without exceeding the width of the patient table and therefore ensure good access to the patient. Besides the integration of this new coil geometry into an existing simulation framework, the simulation is validated by comparing the results to a self-built coil and an already established coil geometry. In addition to this, the application of the coil in different scanner topologies is evaluated.BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt 104 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -Magnetic Particle Imaging (MPI) is a novel medical imaging technology that is able to acquire the distribution of superparamagnetic iron oxide nanoparticles in real-time with high spatial and temporal resolution. Spatial encoding is realized by a magnetic field configuration generating a field-free point (FFP). Therefore, the FFP is moved through the field of view (FOV). However, at low particle concentrations the signal-to-noise ratio (SNR) decreases and therefore image quality worsens. An enhanced encoding scheme uses instead of the FFP the concept of a field-free line (FFL), whereby a gain of sensitivity of one order of magnitude can be realized. Simulation studies approximate power consumption to a minimum and improve field homogeneity with the result that fast Radon-based reconstruction techniques are feasible. On the basis of these studies, this book describes the manufacturing of an optimized scanner topology realizing an excellent field quality with the help of customized curved rectangular coils. Furthermore, the power loss is efficiently minimized.BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt 80 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -The air flow to the lungs is disturbed by a partial or complete collapse of the upper airways of patients suffering from Obstructive Sleep Apnea. Numerical simulations on patient specific models may be used to extract pathophysiological parameters like flow velocity and pressure distribution in the human pharynx and can evaluate the severity of the disease and the success of a therapy. In this work, Computational Fluid Dynamics are used to simulate the air flow in the natural pharyngeal geometry of a patient as well as in the deformed pharyngeal geometry of the same patient treated with a dental appliance. The simulations are performed with two different types of boundary conditions. It is found that a realistic choice of a pressure drop boundary condition shows a significant change in the pressure distribution for the different geometries. In using an inflow velocity as boundary condition a change in the dimensionless Reynolds number based on the flow velocity can be observed. However, a comparison of two different turbulence models showed no significant differences in the flow predictions.BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt 112 pp. Englisch.

Zustand: good. Befriedigend/Good: Durchschnittlich erhaltenes Buch bzw. Schutzumschlag mit Gebrauchsspuren, aber vollständigen Seiten. / Describes the average WORN book or dust jacket that has all the pages present.

Taschenbuch. Zustand: Neu. Neuware -Magnetic particle imaging (MPI) estimates the spatial distribution of super-paramagnetic iron-oxide nanoparticles (SPIOs) via the magnetization response of the particles subjected to static and ocillatory magnetic fields. This book focuses on the physics of the SPIOs with emphasis to the application in MPI and gives a brief introduction to the related particle physics. Stochastical Langevin equations are used to simulate the magnetization response. The stochastic differential equations, which incorporate the Néel and the Brown relaxation processes, are derived in detail and solved numerically. The solutions are validated with respect to the related Fokker-Planck equation. Subsequently, simulation studies are carried out to compare different particle parameters like the hydrodynamic diameter or the particle anisotropy with respect to the frequency of the magnetic excitation fields. In addition, a less complex particle model based on ordinary differential equations is presented to fit measurement data of a magnetic particle spectrometer. This optimization task is carried out by a new 2-dimensional continuous genetic algorithm.BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt 128 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -Magnetic Particle Imaging (MPI) is a novel imaging modality that uses various static and oscillating magnetic fields to image the spatial distribution of superparamagnetic iron oxide nanoparticles (SPIOs) with high sensitivity, no tissue background, and no ionizing radiation. The method exploits the non-linear magnetization behavior of the SPIOs, and has shown great potential to surpass current in vivo imaging modalities in terms of sensitivity, safety, quantitation, and spatio-temporal resolution. MPI is well suited for clinical applications such as angiography, cancer imaging, and inflammation imaging; as well as research applications such as stem cell imaging and small animal imaging.BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt 188 pp. Englisch.

Zustand: Hervorragend. Zustand: Hervorragend | Sprache: Englisch | Produktart: Bücher.

Zustand: Hervorragend. Zustand: Hervorragend | Sprache: Englisch | Produktart: Bücher.

Zustand: Hervorragend. Zustand: Hervorragend | Sprache: Englisch | Produktart: Bücher.

Taschenbuch. Zustand: Neu. Neuware -The 9th International Workshop on Magnetic Particle Imaging took place in New York, March 2019. Since the first workshop in 2010, the International Workshop on MPI (IWMPI) has been the premier forum for researchers working in the MPI field. The workshop aims at covering the status and recent developments of both the instrumentation and the tracer material, as they are equally important in designing a well performing MPI system. The main topics presented at the workshop include hardware developments, image reconstruction and systems theory, nanoparticle physics and theory, nanoparticle synthesis, spectroscopy, patient safety, and medical/research applications of MPI: iwmpi.org.BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt 276 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -This book concludes the results of the 2nd symposium on functional or regulatory autoantibodies targeting G-protein-coupled receptors (GPCRs) in Lübeck in 2018.GPCRs are involved in a variety of physiological and pathophysiological processes. So far, much effort has been made on anti-GPCR drug discovery with a focus on the development of small molecules for the treatment of cancer, infection, metabolic disorders or inflammatory diseases.Recently, functional autoantibodies against GPCRs were identified in healthy donors and were found to be dysregulated in various diseases. They are associated with pathogenesis, uncovering a potential new field of therapeutic intervention.Thus, the aim of the symposium in 2018 was to combine the current knowledge about the role of anti-GPCR ab in different pathologies, their mode of action and state-of-the-art research techniques to identify common fundamental pathways that can be transferred to other disease entities with similar manifestations.BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt 120 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -The contributions to this proceedings book show how new approaches and methods in medical engineering and medical informatics can advance medicine, health and health care. The papers focus on the following topics: Biomedical Optics, Biochemical Physics, Biomedical Engineering, Safety and Quality, E-Health, Signal Processing, Medical Imaging, and Image Processing.BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt 296 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -This volume shows how new approaches and methods in medical engineering and medical informatics can advance medicine, health, and health care. The Student Conference is an annual event at the BioMedTec Science Campus Lübeck. The Congress is organized by the Universität zu Lübeck and the University of Applied Science Lübeck. Master students of programs related to medical engineering science, medical informatics, biomedical engineering, and auditory technology present results of their recent research projects. 392 pp. Englisch.

Zustand: Hervorragend. Zustand: Hervorragend | Sprache: Englisch | Produktart: Bücher.

Buch. Zustand: Neu. Neuware -In this book, a functional contrast of the human neurons in the retina based on the phase information of the optical coherence tomography (OCT) signal is presented. To gain access to the phase information, data is recorded with a full-field swept-source OCT. By axial and lateral parallelization of the data acquisition, the influence of motion artifacts on the phase can be minimized, so that the phase information is available for an analysis of the physiological changes of the sample.In this book, the technical implementation of full-field imaging, the algorithms necessary for the phase analysis, such as registration, segmentation, numerical aberration and dispersion correction, and the phase analysis itself are presented. This recording technology, combined with the numerical processing, was then used to detect functional changes in the neurons of the retina. Functional changes in both the photoreceptors and the inner plexiform layer (IPL) were detected and the functional contributions of different cell types to the phase change were differentiated. 192 pp. Englisch.

Buch. Zustand: Neu. Neuware -Patient-specific finite element modelling of bone is a promising method for surgical planning, implant design and the prediction of bone remodelling or fracture risks, yet the assignment of material properties is challenging. Bone is a complicated structure with direction-dependent, inhomogeneous material properties, influenced by compositional, geometrical and architectural aspects. This volume focuses on a density-based assignment of orthotropic bone properties. Elasticity-density relationships in homogenized femoral zones were examined to evaluate the orthotropic density-dependence of the nine elastic material constants locally. Cortical bone samples were tested in compression and torsion tests using videoextensometry to determine the elastic constants. The elastic properties of cancellous bone were predicted by micro finite element analysis. All determined constants were correlated to the radiological bone mineral density of each sample, which was determined by quantitative computed tomography. The trabecular eigensystem was investigated for each cancellous zone to assign the mean directionality of trabecular fabric. The results can be beneficial for density-based orthotropic material assignment in femoral patient-specific finite element models.BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt 240 pp. Englisch.

Zustand: Sehr gut. Zustand: Sehr gut | Sprache: Englisch | Produktart: Bücher.

Buch. Zustand: Neu. Neuware -This congress volume compiles the contributions of the Bone Innovation Summit as well as an overview of current research results in the field of orthopedics and traumatology from the last three years.The Northopedics, BONEBANK and BFCC projects, launched three years ago, focus on improving fracture treatment in northern Germany, the Danish-German border region and the Baltic Sea countries. The projects address the different perspectives of patients, physicians, clinics, researchers, industry and regulatory authorities on improving fracture care.The overall aim of the projects is to foster innovation through register research and to improve the funding conditions for research projects. In addition, a number of approaches for the harvesting of stem cells for therapies were evaluated and concepts for new medical devices were developed.BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt 176 pp. Englisch.

Buch. Zustand: Neu. Neuware -In the context of individualized medicine and in the age of 4D imaging, current research covers the plausible personalized, visuo-haptic Virtual Reality (VR) immersion for training and planning of puncture interventions. In this book, this subject is first overviewed and presented regarding the technical details by selected English scientific publications.The patient model results from a mostly automatic procedure for the segmentation of puncture-relevant organs and structures. For increased realism, the influence of simulated respiratory movement extracted and modeled from 4D-CT images was also taken into account. Based on these modeling steps, innovative, efficient GPU algorithms for volume-based visuo-haptic simulation and the direct volume rendering of physiological processes of the patient model were proposed. For a time-invariant patient model, the local consideration of space bending mathematically introduced by an inverted movement model leads to efficient visuo-haptic rendering methods: Simulated imaging of ultrasound, fluoroscopy, the stereoscopic two-eye perspective and haptics are elaborated. This approach eventually allowed the immersive interaction of the ultrasound probe and puncture needle with breathing virtual patients.The methods were developed in cooperation with clinical partners and successfully applied and evaluated in a user study. The medical potential of the methods presented in this work lies in the future in the pre-operative and personalized preparation of interventions. Specifically, for the described application of liver punctures, the number of needle repositionings could be significantly reduced, relieving the patient and saving treatment costs.BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt 196 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -Additive manufacturing, often referred to as 3D printing, has long since proven its suitability for everyday use. However, many questions remain unanswered for use in medicine. Complex melting and hardening processes take place during the layer-by-layer construction of medical devices from liquid or solid materials, the physical-chemical modelling of which is often still pending, so that a discussion forum is to be given at AMMM on topics relating to the achievable precision and the expected technical properties of the medical devices produced in this way. Questions about the precision and interaction of the printed materials with their future application matrix are important for all industries. However, these requirements are of particular interest in the medical environment, where biological compatibility and long-term stability are of particular importance. Medical technology companies are also faced with the question of whether this modern manufacturing technology should only be used in prototype and individualized sample development or also in series production. Costs and benefits have to be assessed very individually. AMMM 2019 will focus on these questions, with particular emphasis on the medical device regulation of patient-specific devices.BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt 236 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -This volume shows how new approaches and methods in medical engineering and medical informatics can advance medicine, health, and health care. The Student Conference is an annual event at the BioMedTec Science Campus Lübeck. The Congress is organized by the Universität zu Lübeck and the University of Applied Science Lübeck. Master students of programs related to medical engineering science, medical informatics, biomedical engineering, and auditory technology present results of their recent research projects.Books on Demand GmbH, Überseering 33, 22297 Hamburg 548 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -This volume shows how new approaches and methods in medical engineering and medical informatics can advance medicine, health, and health care. The Student Conference is an annual event at the BioMedTec Science Campus Lübeck. The Congress is organized by the Universität zu Lübeck and the University of Applied Science Lübeck. Master students of programs related to medical engineering science, medical informatics, biomedical engineering, and auditory technology present results of their recent research projects.Books on Demand GmbH, Überseering 33, 22297 Hamburg 556 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -This volume shows how new approaches and methods in medical engineering and medical informatics can advance medicine, health, and health care. The Student Conference is an annual event at the BioMedTec Science Campus Lübeck. The Congress is organized by the Universität zu Lübeck and the University of Applied Science Lübeck. Master students of programs related to medical engineering science, medical informatics, biomedical engineering, and auditory technology present results of their recent research projects.Books on Demand GmbH, Überseering 33, 22297 Hamburg 556 pp. Englisch.