elsevier science technology jan 2000 (7 Ergebnisse)

Taschenbuch. Zustand: Neu. Neuware - Security Investigations is a comprehensive book that covers the full spectrum of investigative issues. It contains practical self-evaluation exercises that can be applied in both a formal or informal training environment. Corporate security supervisors will find it helpful in establishing policies and procedures for conducting investigations. It is a guide also for those responsible for the security function without prior experience. ie. Director of Human Resources. Forms in the book will assist an organization in standardizing the means to conduct investigations as well as reporting the outcome in a way that ensures that nothing was missed during the investigation. The real worth of an investigator is their ability to adapt to ever changing circumstances. This text gives the investigator a quick reference manual that can be used to: develop the investigation plan, take effective and accurate field notes, conduct an interview, perform surveillance and finally write the report, all within the legal guidelines outlined in the book. As an additional bonus to the reader, the book will include information on how to select and use the proper surveillance equipment.

Taschenbuch. Zustand: Neu. Neuware - In 1999 the IFAC/IFIP Workshop on Real Time Programming (WRTP) joined forces with the Workshop on Active and Real-Time Database Systems (ARTDB). Both series of workshops provide an excellent forum for exchanging information on recent scientific and technological advances and practices in real time computing, a field that is becoming an essential enabling discipline of both control engineering and computer science and engineering.

Taschenbuch. Zustand: Neu. Neuware - This is a no-nonsense, practical book for helping organizations rid their workplaces of drug abuse and its serious and costly consequences. The book draws upon the collective experiences of hundreds of organizations that have said no more, not here and have grown stronger as a result. The path to a drug-free working environment is straight but narrow. The Drug-Free Workplace: How to Get There and Stay There delineates the path, always with a view toward avoiding missteps that can lead to trouble.

Buch. Zustand: Neu. Neuware - Genetic Aberrancies and Neurodegenerative Disorders presents critical reviews and emerging findings concerning the roles of genetic mutations and polymorphisms in the pathogenesis of a range of neurological disorders including Alzheimer's and Parkinson's diseases, trinucleotide repeat disorders, stroke, epilepsy and others. This volume, written by leading experts, brings together fundamental information concerning the roles of inherited traits in the pathogenesis of different neurodegenerative disorders. In addition to providing a catalogue of the known genetic alterations that are linked to specific neurodegenerative disorders, the chapters detail the current state of understanding of the cellular and biochemical mechanisms whereby the genetic aberrancies lead to neuronal dysfunction and degeneration. The emerging picture of each disorder, painted by pathological, biochemical and molecular brushes, suggests that they share key mechanisms including increased levels of oxidative stress, perturbed ion homeostasis, mitochondrial dysfunction and apoptotic proteolytic cascades. The existence of specific molecular defects provides the opportunity to design experiments that can establish the precise pathogenic mechanism of a specific mutation or genetic risk factor. The value of this approach is exemplified by recent studies of how mutations in Cu/Zn-superoxide dismutase cause amyotrophic lateral sclerosis and how presenilin mutations result in early-onset Alzheimer's disease. A theme developed among the different chapters is that events that occur during aging predispose neurons to genetic aberrancies that promote degenerative cascades, and that specific genetic defects exert their influence on particular populations of neurons in a disorder-specific manner. The chapters in this volume will stimulate readers to generate new hypotheses concerning the pathogenic mechanisms of genetic aberrancies that can be experimentally tested.

Buch. Zustand: Neu. Neuware - The present volume focuses on microbial invasion strategies of pathogen uptake. An accompanying volume (Vol. 5) in the series presents the phagocytic process from the viewpiont of the host cell. This field of study is growing rapidly after a somewhat slow start over recent decades. This collection of invited chapters attempts to reflect current research and brings together cell biologists, microbiologists, and immunologists wiht disthemes, hopefully like a symphony rather than a boring catalogue. It will be evident that editorial bias favors intracellular parasitism and medically important organisms. The neutrophil is far more than a supporting player to the macrophage and some attempt is made to remind the reader of some of its unique skills. To retain a manageable size, the emphasis is on relatively early events such as mutual recognition, cell entry, and response, rather than on longterm changes in gene expression by either host cell or pahtogen. Viruses are excluded not because of lack of importance but because of somewhat different research approaches, although it is becoming increasingly clear that large viruses (e.g. Vaccinia) and Listeria monocytogenes, share common strategies in invasion and intercellular spread.

Buch. Zustand: Neu. Neuware - This volume presents work from six different groups working on various aspects of cycloaddition chemistry. José Mascareñas gives us a very interesting account of the chemistry of &Bgr;-alkoxy-&ggr;-pyrones and related species. Al Padwa and Chris Staub discuss further advances in rhodium carbenoid chemistry and the unusual cycloaddition processes possible with these intermediates. Higher order cycloadditions mediated by transition metals highlight Jim Rigby's update on his group's efforts in this area. Lily Lee and John Snyder present us with a detailed account of the indole ring as a dienophile, challenging us to consider the untapped potential in this area. Brian Keay and Ian Hunt discuss the intramolecular Diels-Alder reactions of furan; a report that is both top-notch science, and what could be a great learning tool for students who need to see how fundamental chemical principles can and should be applied to synthetic problems. Finally, Kay Brummond introduces us to a new version of the Pauson-Khand reactions, one that will no doubt be further exploited in productive ways by her group well into the future.

Buch. Zustand: Neu. Neuware - The International Conference on Mechanical Design and Production has over the years established itself as an excellent forum for the exchange of ideas in these established fields. The first of these conferences was held in 1979. The seventh, and most recent, conference in the series was held in Cairo during February 15-17, 2000.