elsevier science publishing co inc jun 2024 (22 Ergebnisse)

Taschenbuch. Zustand: Neu. Neuware - Chromatin: Structure, Function, and History brings the reader up to date on the remarkable progress made in chromatin research over the course of the past 50 years. Coverage includes the basics of chromatin biology, beginning with the discoveries that culminated in the recognition of the nucleosome as the basic subunit of chromatin. Chromatin folding, nucleosome positioning, and histone variants are discussed, as well as research on chromatin modifications and remodeling, which exploded in the early to mid-1990s and led to widespread interest in epigenetics. Considerable attention is given to methods and experiments that led to key insights, and recent developments such as the use of genome-wide approaches and innovations in imaging approaches are also emphasized. By providing historical background together with detailed discussion of contemporary studies, the book aims to instill in the reader an appreciation not only of our current knowledge of chromatin structure and function, but also of the remarkable path that has taken chromatin to the forefront of modern research.

Taschenbuch. Zustand: Neu. Neuware - Advanced Calculus for Mathematical Modeling in Engineering and Physics: With Discrete and Numerical Analogies introduces the principles and methods of advanced calculus for mathematical modeling through a balance of theory and application using a state space approach with elementary functional analysis. This framework facilitates a deeper understanding of the nature of mathematical models, and of the behavior of their solutions. The work provides a variety of advanced calculus models for mathematical, physical science, and engineering audiences, with discussions on how calculus-based models and their discrete analogies are generated. This valuable textbook offers scientific computations driven by Octave/MATLAB script.

Taschenbuch. Zustand: Neu. Neuware - Human Nutrition: From Molecular Biology to Everyday Life presents an integrated approach on how nutrients and non-nutrients affect cellular biochemistry, and how, in turn, they shape human physiology. Over the course of 8 chapters, and covering topics ranging from the importance of diet on health to nutrigenetics and nutrigenomics, this book debunks myths and provides readers with the knowledge they need to critically interpret and navigate nutrition information. Intended for nutritionists, dieticians, pharmacists, public health professionals, and others working in related fields, this book provides a comprehensive source on advances in human nutrition.

Taschenbuch. Zustand: Neu. Neuware - Revealing Uncharted Biology with Single Cell Multiplex Proteomic Technologies: ApplicationsHealthy tissues and organs rely on the precise coordination of diverse cell types, each responding to external and internal signals. Disease disrupts this coordination. Since proteins drive cellular function, analyzing their abundance and activation states in single cells helps identify key cell populations in health and disease. Bulk protein analyses mask critical differences between individual cells. Additionally, the arrangement of cells into neighborhoods through cell-cell interactions is essential for tissue function. Over the last decade, single-cell proteomic phenotyping combined with positional information has become crucial for understanding biology in health and disease. This has led to the development of multiple technology platforms, profoundly impacting fields including developmental biology, cancer biology, immunology, neuroscience, and drug discovery. This book focuses on the application of single-cell multiplex proteomic platforms to various biological systems. These platforms have proved to be essential in biomedical research, advancing our understanding of complex biological systems at the cellular level. Compelling studies where authors use these technologies to answer previously unanswerable questions are featured. Exploring this 'Uncharted Biology' opens new avenues for scientific inquiry and clinical translation, covering areas including oncology, immunology, metabolomics, stem cell research, preclinical models, and translational research. The initial chapters discuss incorporating these technologies into core facilities and consortia, providing access for multiple users and integrating datasets from other omics technologies. The following chapters cover applications in diverse areas such as muscle stem cell function in skeletal muscle regeneration, metabolic regulome profiling, translational studies, developing predictive biomarkers for patients receiving immune checkpoint inhibitors, and pre-clinical studies of lung cancer. These applications demonstrate how advanced single cell proteomic technologies are reshaping our understanding of complex biological systems and enhancing clinical translation. Revealing Uncharted Biology with Single Cell Multiplex Proteomic Technologies: Applications highlights the transformative benefits of single-cell proteomics, offering insights into cellular mechanisms underlying health and disease and inspiring further exploration into 'Uncharted Biology.' It is an essential resource for researchers, clinicians, and students aiming to advance biomedical science and improve therapeutic outcomes.

Taschenbuch. Zustand: Neu. Neuware - Intelligent Fractal-Based Image Analysis: Application in Pattern Recognition and Machine Vision provides insights into the current strengths and weaknesses of different applications as well as research findings on fractal graphics in engineering and science applications. The book aims to improve the exchange of ideas and coherence between various core computing methods and highlights the relevance of related application areas for advanced as well as novice-user application. The book presents core concepts, methodological aspects, and advanced feature opportunities, focusing on major, real-time applications in engineering and health science. It will appeal to researchers, data scientists, industry professionals, and graduate students. Fractals are infinite, complex patterns used in modeling physical and dynamic systems. Fractal theory research has increased across different fields of applications including engineering science, health science, and social science. Recent literature shows the vital role fractals play in digital image analysis, specifically in biomedical image processing. Fractal graphics is an interdisciplinary field that deals with how computers can be used to gain high-level understanding from digital images. Integrating artificial intelligence with fractal characteristics has resulted in new interdisciplinary research in the fields of pattern recognition and image processing analysis.

Taschenbuch. Zustand: Neu. Neuware - Bio-inoculants in Horticultural Crops, Volume Three in the Advances in Bio-inoculant series, focuses on real-time application of novel microbes that have been proven to enhance and improve plant health and productivity. The book provides comprehensive information on a range of biological approaches and mechanisms for the improvement of horticultural crops being practiced in different production systems. Covering the subject from historical developments to recent advances in microbial interventions, it addresses the potential role and bio-mechanism of bio-inoculants for challenges including stress tolerance, production, commercialization, application methodology, challenges and future roadmap for sustainable production system of horticultural crops. This volume will be useful to scientists, academicians, and students of horticulture, agriculture microbiology, plant protection, and other related subjects.

Taschenbuch. Zustand: Neu. Neuware - Advancement of Phenolic Acids in Drug Discovery: Fundamental and Applications offers comprehensive coverage of the ADMET profiles of phenolic acids, their extraction method and prospects for drug design and development. Chapters overview phenolic acids and their characterization, discuss the role of phenolic acids in plant systems, present sources and detailed extraction methods of phenolic acids, and cover phenolic acid mechanisms of action as it relates to several key diseases and health conditions, including their role as antioxidant agents, anti-inflammatory and analgesic drugs, anti-microbial drugs, anti-viral drugs, anti-cancer drugs, diabetes and metabolic dysfunctions, neurological disorders, cardiovascular diseases. The book's final chapters cover nanoscience aspects of phenolic acids, biomedical applications, and concludes with challenges and opportunities presented by phenolic acids. This is the ideal reference for researchers in the fields of drug development, both in academia and corporate settings. Researchers of related areas like food science and medicinal chemistry will also benefit from this in-depth profiling of therapeutical properties of phenolic acids.

Buch. Zustand: Neu. Neuware.

Buch. Zustand: Neu. Neuware.

Taschenbuch. Zustand: Neu. Neuware - Implementing sustainability solutions in Information Technology (IT) or broader - in Information Communications Technology (ICT) - is a challenge but it is essential. The goal of Making IT Sustainable: Techniques and Applications is to show how it has been done, strategies, various solutions, tool sets, and best practices. Various IT areas are investigated - from data center technologies and operations to cloud computing, to green software, to cryptocurrency, to the transformative AI role in making IT sustainable, to quantum and adiabatic computing. The adoption of sustainable IT practices reduces the environmental footprint of IT by advocating for the utilization of renewable energy sources, electronic waste reduction, the design of energy-efficient IT devices, innovative cooling technologies, and circular economy. Sustainable IT is a complex and challenging field. As a result, there are many questions and uncertainties about how to implement sustainable practices across various scenarios. Making IT Sustainable: Techniques and Applications asks several insightful questions: How can environmentally sustainable data centers be built How do we compare the carbon footprint of data centers versus public cloud, and cloud-focused IT sustainability standards As growth in data traffic such as video streaming requires additional internet infrastructure, leading to higher emissions, how is this challenge being addressed and how can we improve energy efficiency in IT such as Adiabatic Reversible Computing, use of direct current, and dematerialization are discussed Readers of Making IT Sustainable: Techniques and Applications will be a very diverse group. First, the readers include IT professionals who are responsible for managing and maintaining IT infrastructure and systems. The book can provide them with knowledge and guidance on how to reduce the environmental impact of their IT operations. Second, business leaders making decisions about the use of IT will find guidance in the book on how to implement sustainable IT practices in their organizations. Academics and researchers interested in the field of sustainable IT will find information and data helping them develop new ideas and innovative approaches to IT sustainability. The goal of IT sustainability is to contribute to making our planet better. Therefore, students who are interested in pursuing careers in IT or sustainability are the most important members of the book audience. The book helps them understand the key role of sustainability in IT and develop skills and knowledge in this field. Overall, everyone who is interested in reducing the environmental impact of IT can benefit from this book on sustainable IT, regardless of their professional background or level of expertise. Making IT Sustainable: Techniques and Applications is written by an IT practitioner actively working in the field of sustainable IT. The author has firsthand knowledge of the challenges and opportunities of implementing sustainable practices in IT operations. Readers will find practical solutions with examples of their implementations.

Buch. Zustand: Neu. Neuware.

Taschenbuch. Zustand: Neu. Neuware - Joint Replacement in the Human Body provides a comprehensive exploration of artificial joint designs. The book's primary focus is to introduce readers to the diverse landscape of artificial joint technologies while offering insights into their historical development. This book is divided into three sections, each addressing specific aspects of joint replacements. The first section delves into artificial joints of the lower limb, including the hip, knee, and ankle. In the subsequent section, the book explores upper limb replacements, covering joints such as the shoulder, elbow, wrist, finger, and thumb.The third section tackles broader themes like biotribology, regulatory aspects of joint replacements, examines noteworthy case studies like metal-on-metal hips, and addresses joint replacements not easily categorized in the previous sections, such as spinal total disc replacements. This book offers a critical assessment of the diverse and evolving design concepts currently in use, ranging from established metal-on-polymer joints to innovative biomimetic solutions. This book is designed to swiftly equip readers with a deep understanding of contemporary joint replacements and the immediate and long-term challenges they present.

Buch. Zustand: Neu. Neuware.

Taschenbuch. Zustand: Neu. Neuware - Federated Learning for Digital Healthcare Systems critically examines the key factors that contribute to the problem of applying machine learning in healthcare systems and investigates how federated learning can be employed to address the problem. The book discusses, examines, and compares the applications of federated learning solutions in emerging digital healthcare systems, providing a critical look in terms of the required resources, computational complexity, and system performance. In the first section, chapters examine how to address critical security and privacy concerns and how to revamp existing machine learning models. In subsequent chapters, the book's authors review recent advances to tackle emerging efficient and lightweight algorithms and protocols to reduce computational overheads and communication costs in wireless healthcare systems. Consideration is also given to government and economic regulations as well as legal considerations when federated learning is applied to digital healthcare systems.

Taschenbuch. Zustand: Neu. Neuware - Biochar Production for Green Economy: Agricultural and Environmental Perspectives addresses the advancements and developments for the efficient diversification of biochar toward achieving improved agricultural and environmental benefits. This comprehensive and cohesive volume is the first to address the potential multi-and transdisciplinary opportunities of effective biochar production and use. Including the potential applicability of not only crop waste biochar but weeds, agroforestry, agroindustry, municipal waste, as well chapters explore surface modified, enriched or tailored biochar for soil amendment, GHGs mitigation, bioremediation of organic, inorganic, metals and other emerging pollutants, as well as soil remediation. It also covers the trending multidisciplinary approaches of nanotechnology, surface chemistry and thermal decomposition advancements being adopted for capacity enhancement and versatile applicability in the field of agriculture, environment science and green energy synthesis. Composition and characteristics of tailored biochar, their interactions, and transformation into the soil and water ecosystem are illustrated. This book is a valuable resource for those pursuing biochar related areas as well as those seeking environmentally sustainable solutions to crop, soil or water issues.

Taschenbuch. Zustand: Neu. Neuware - Handbook of Stretchable and Elastomeric Textiles is a comprehensive guide to everything you need to know about elastomeric textiles, including manufacturing techniques, physical properties, processing methods, and in-use care. All types of stretchable textiles are covered, including polymers, fibers, yarns, fabrics and composites. Starting with the fundamentals of the synthesis, properties and processing of elastomeric materials, this book goes on to help the reader choose the most appropriate parameters for manufacturing and processing, as well as the best elastomeric material according to specific end use applications. In general, elastomeric textiles are difficult to handle. During the manufacturing of elastomeric fabric, the handling of yarns is complicated. In addition, the processing stage is also challenging due to the heat sensitivity of the materials that affects how they are dyed, printed, washed and dried. The specific techniques required to produce a successful elastomeric textile have been developed over many years, hence this expertise is hard to come by.

Buch. Zustand: Neu. Neuware.

Taschenbuch. Zustand: Neu. Neuware - Functionalization of 2D Materials and Their Applications reviews the synthesis and characterization of nanopatterned 2D materials and how to modify different substrates with these materials. Each chapter emphasizes fabrication, including the fabrication of different morphologies of graphene and transition metal dichalcogenides (TMDCs), the fabrication of different composites and the surface modification of different nanopatterned graphene and TMDCs, and the effects of these nanostructures on the different properties of the modified substrates, such as the electrical, thermal and optical properties, and more. The applications of graphene and TMDCs in the enhancement of Raman spectroscopy, solar cells, fuel cells, supercapacitors, biosensors, chemical sensors, water treatment, water desalination, perovskite photodetectors, energy storage devices, environmental applications and cell-based chips are also reviewed.

Taschenbuch. Zustand: Neu. Neuware - Fused Pyranones: Multifaceted Building Blocks for Molecular Diversity covers the synthesis and chemical reactivity of fused pyranone ring systems, such as coumarin, isocoumarin, chromonone, chroman-4-one, and others, as well as their applications in the fields of drug discovery and material sciences. Mechanisms of the chemical reactions are covered, along with the steps to formation of final products. This book is ideal for organic, medicinal and material chemists and researchers working to build target compounds for pharmaceuticals and materials, as well as those working in food supplements, perfumery, and cell and animal imaging.

Taschenbuch. Zustand: Neu. Neuware - Functionalized Nanomaterials for Biosensing and Bioelectronics Applications: Trends and Challenges describes current and future opportunities for integrating the unique properties of two-dimensional nanomaterials with bioelectronic interfaces. Sections focus on background information and fundamental concepts, review the available functionalized nanomaterials and their properties, explore the integration of functionalized nanomaterials with bioelectronics, including available fabrication and characterization methods, electrical behavior at the interface, and design and synthesis guidelines, and review examples of microsystems where functionalized nanomaterials are being integrated with bioelectronics. This book is suitable for researchers and practitioners in academia and R&D working in materials science and engineering, analytical chemistry, and related fields.

Buch. Zustand: Neu. Neuware.

Taschenbuch. Zustand: Neu. Neuware - Medical Modelling: The Application of Advanced Design and Rapid Prototyping Techniques in Medicine, Third Edition¿provides readers with a thorough update of the core contents, along with key information on innovative imaging techniques, additive manufacturing technologies, and a range of applied case studies. This comprehensive new edition includes new coverage of advanced technologies, such as selective laser melting, electron beam melting, multi jet fusion, and more. The extensive section of peer-reviewed case studies is thoroughly updated and includes additional clinical examples, describing the practical applications of advanced design technologies in surgical, prosthetic, orthotic, dental and research applications.Finally, the book explores the future potential of medical modeling, such as in simulations for training, the development of new medical devices, and more.