elsevier science publishing co inc jun 2023 (12 Ergebnisse)

Taschenbuch. Zustand: Neu. Neuware - Up and Running with AutoCADª 2024 presents a combination of step-by-step instructions, examples and insightful explanations. The book emphasizes core concepts and practical application of AutoCAD in engineering, architecture and design. Written with the user in mind, this book is equally useful in instructor-led classroom training, self-study or as a professional reference.

Taschenbuch. Zustand: Neu. Neuware - Partial Differential Equations and Applications: A Bridge for Students and Researchers in Applied Sciences offers a unique approach to this key subject by connecting mathematical principles to the latest research advances in select topics. Beginning with very elementary PDEs, such as classical heat equations, wave equations and Laplace equations, the book focuses on concrete examples. It gives students basic skills and techniques to find explicit solutions for partial differential equations. As it progresses, the book covers more advanced topics such as the maximum principle and applications, Green's representation, Schauder's theory, finite-time blowup, and shock waves. By exploring these topics, students gain the necessary tools to deal with research topics in their own fields, whether proceeding in math or engineering areas.

Buch. Zustand: Neu. Neuware - Advances in Applied Microbiology, Volume 123 continues the comprehensive reach of this widely read and authoritative review source in microbiology. Users will find invaluable references and information on a variety of areas relating to the topics of microbiology.

Taschenbuch. Zustand: Neu. Neuware - Linear Algebra: Algorithms, Applications, and Techniques, Fourth Edition offers a modern and algorithmic approach to computation while providing clear and straightforward theoretical background information. The book guides readers through the major applications, with chapters on properties of real numbers, proof techniques, matrices, vector spaces, linear transformations, eigen values, and Euclidean inner products. Appendices on Jordan canonical forms and Markov chains are included for further study. This useful textbook presents broad and balanced views of theory, with key material highlighted and summarized in each chapter. To further support student practice, the book also includes ample exercises with answers and hints.

Taschenbuch. Zustand: Neu. Neuware - pH Deregulation as the Eleventh Hallmark of Cancer presents key concepts about pH deregulation in a concise and straight-forward manner. The book discusses topics such as pH regulation and metabolism, sodium hydrogen exchanger, monocarboxylate transporter, V-ATPase proton pump, carbonic anhydrases, and voltage gated sodium channels. In addition, it covers clinical and therapeutic implications and future perspectives. This is a valuable resource for researchers, oncologists, students and members of the biomedical and medical fields who want to learn more about the role of pH deregulation in cancer treatment. pH deregulation can improve the outcome of classical treatments without adding toxicity to them, and the book shows that treating the pH peculiarities of cancer is simple and can be performed with existing drugs. Based on the classification of tumor malignancy in ten hallmarks, the authors put pH deregulation at the spotlight and separated from metabolic reprogramming due to its impact on all other hallmarks, proposing it as an additional characteristic to evaluate and fight cancer.

Taschenbuch. Zustand: Neu. Neuware - Overexpression of receptor tyrosine kinases (RTKs) has been implicated in cancer. Increasing evidence suggests that dysregulation of RTKs is reported in many neurodegenerative and psychiatric disorders. Receptor Tyrosine Kinases in Neurodegenerative and Psychiatric Disordersprovides a fundamental, pragmatic map of RTKs structure, activation, functions, mechanism of action, gene regulation, and signaling pathways in developing central nervous system (CNS), adult normal CNS, neurodegenerative and psychiatric disorders. Additionally, the structure, function, activation, and therapeutic potential of many growth factors have been covered. Here, international experts in the field offer a comprehensive discussion of results of pre-clinical and clinical studies of repositioning of anti-cancer receptor tyrosine kinase inhibitors(RTKIs) and other promising protein kinase inhibitors in various neurodegenerative disorders including, Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, Huntington's disease, and multiple sclerosis, and psychiatric disorders including, anxiety, depression, alcohol use disorder, and schizophrenia. In addition, the book discusses the obstacles and opportunities for the potential repositioning of kinase inhibitors in neurodegenerative and psychiatric disorders.

Taschenbuch. Zustand: Neu. Neuware - Genomic Surveillance and Pandemic Preparedness offers practical, in-depth instruction in where, how, and why genomic surveillance may be applied. Drawing heavily from the learnings during the COVID-19 pandemic, this book covers different aspects of microbes with a focus on viral genome sequencing and analysis, implementation and inference of genomic surveillance, and global data sharing best practices for future pandemic preparedness. Here, more than a dozen international authors consider host and pathogen genome interaction, population-level prevalence, individual disease susceptibility and gene protection, pathogen mutation evolutionary dynamics, RNA modulation of infection, pathogen diversity, and the role of coinfections and comorbidities in disease severity. A wide range of examples, from bacterial pathogens to fungal and viral infections, with an emphasis on recent COVID-19 analysis, are discussed. Finally, the authors provide step-by-step instruction in experimental and computational approaches for genomic surveillance, including nucleic acid isolation, sequencing library preparation, functional sequencing analysis, and bioinformatics pipelines. Throughout this book, importance is placed on inference-moving from genomic sequencing to meaningful genomic surveillance that bolsters pandemic preparedness.

Taschenbuch. Zustand: Neu. Neuware - Pharmacogenomics: From Discovery to Clinical Implementation is a complete reference aimed at building a solid foundation of the key concepts in this fast-moving knowledge area. The book's chapters over the foundational aspects of pharmacogenomics, including drug metabolism, drug discovery, development, and testing, and then detail studies of key health conditions and the potential therapeutic applications of pharmacogenomics. Diseases covered include diabetes, cardiovascular diseases, psychiatric disease, cancer, pulmonary and respiratory diseases, viral diseases, gastroenterology, autoimmune diseases, immunosuppressants, and, finally, an overview of computational resources. This is the perfect resource for pharmaceutical science graduate students to learn the key concepts of the area. However, researchers and graduate students in the related fields of genetics, pharmacoepidemiology, molecular biology, and medicinal chemistry will also benefit from the structured approach of the book.

Taschenbuch. Zustand: Neu. Neuware - Handbook of Metaheuristic Algorithms: From Fundamental Theories to Advanced Applications provides a brief introduction to metaheuristic algorithms from the ground up, including basic ideas and advanced solutions. Although readers may be able to find source code for some metaheuristic algorithms on the Internet, the coding styles and explanations are generally quite different, and thus requiring expanded knowledge between theory and implementation. This book can also help students and researchers construct an integrated perspective of metaheuristic and unsupervised algorithms for artificial intelligence research in computer science and applied engineering domains. Metaheuristic algorithms can be considered the epitome of unsupervised learning algorithms for the optimization of engineering and artificial intelligence problems, including simulated annealing (SA), tabu search (TS), genetic algorithm (GA), ant colony optimization (ACO), particle swarm optimization (PSO), differential evolution (DE), and others. Distinct from most supervised learning algorithms that need labeled data to learn and construct determination models, metaheuristic algorithms inherit characteristics of unsupervised learning algorithms used for solving complex engineering optimization problems without labeled data, just like self-learning, to find solutions to complex problems.

Buch. Zustand: Neu. Neuware - Pancreatic Cancer: Basic Mechanisms and Therapies, Volume 159 in the Advances in Cancer Research, presents the latest release in this ongoing, well-regarded serial with invaluable information on the exciting and fast-moving field of cancer research.

Taschenbuch. Zustand: Neu. Neuware - Textile reinforcement forms (preforms) play an important role in determining the properties of the final composite and product. The preform formation process provides precise control of the fiber architecture and orientation using a suitable textile manufacturing technique. While the techniques employed for preparing glass and carbon preforms are well-known, there is still a gap in understanding on how to prepare natural preforms for composite reinforcements. Multiscale Textile Preforms and Structures for Natural Fiber Composites will bridge this gap by presenting unified knowledge on the relevant preform preparation techniques and resulting fiber architectures. Emphasis is on the structural parameters of each preform and their effect on the final composite properties. This book assembles information and knowledge on natural fiber reinforcement forms, including conventional forms, such as spun yarn, woven, knitted, nonwoven, braided, and comingled. These are illustrated and classified into one-, two-, and three-dimensional reinforcements. This book also includes information on nonconventional preform formation techniques such as unidirectional tapes, pre-impregnated preforms, spread tows, and tailored fiber placement.

Taschenbuch. Zustand: Neu. Neuware - Sustainable Biodiesel: Real-World Designs, Economics, and Applications offers a unique, integrated approach that combines cutting-edge research results and the day-to-day aspects of biodiesel production at the industrial level. It brings together experienced academics and recognized industry experts to explore the most practical elements of research and discuss the limitations and future needs of the industry. The book critically reviews strategies for implementing biodiesel-based biorefineries, feedstock supply chains, reactor technologies, processes for biodiesel production, and biodiesel combustion, including advanced fuel formulations containing biodiesel. The authors examine biodiesel plants from the point of view of design, operation, quality control, and sustainability, including life cycle assessment (LCA) and life cycle costing (LCC). Policy and regulatory constraints in biodiesel production and commercialization as well as future trends and needs of the industry are also covered.