elsevier bv jun 1996 (7 Ergebnisse)

Buch. Zustand: Neu. Neuware - This series provides a variety of different discussions on topics within the field of growth factors and cytokines in health and disease.

Buch. Zustand: Neu. Neuware - This volume deals with aspects of the cytoskeleton in different cell types and also describe examples of changes in the cytoskeleton which occur during various pathological states. These studies bring the exciting area of cytoskeleton research into the domain of medical science.

Buch. Zustand: Neu. Neuware - This volume is intended to complete the Cell Chemistry and physiology module. It is about how the traditional boundaries of cell chemistry and physiology are being erased by molecular biology. We do not think it necessary to elaborate on this theme, particularly since the body of core knowledge found in this volume brings us a stage closer to answering the question, 'what makes cell biology into a new discipline 'The first part of the volume deals with the chemistry of actin and myosin and is followed by chapters on cell motility, ATP synthesis in muscle, and contraction in smooth and skeletal muscle. Here the reader is immediately made aware of the contributions molecular biology is making to our understanding of the molecular mechanisms underlying muscle contraction. It is perhaps enough to point out that Huxley's concept of the cross-bridge cycle and generation of force can now be explained in molecular terms. Topics such as muscle fatigue and muscle disorders, as well as malignant hyperthermia are bound to arouse active learning in the student and set the stage for problem-based learning.Most medical students look askance at thermobiology. We think this is a mistake; hence, we have included a section dealing with this subject. This brings us to the chapter on the heat shock response, which at the very outset makes clear that many stressors besides heat are known to result in heat shock gene expression. Many of the heat shock proteins occur in unstressed cells and some of them behave as chaperones. These proteins also reach high levels in a wide range of diseases including neurodegenerative disorders. Whether certain diseases are the result of mutations in the heat shock genes is not yet known. As will be appreciated, much of the work done in this field involved the use of cultured cells. Animal cells in culture are the subject of the last chapter.

Buch. Zustand: Neu. Neuware - Part of a series which covers areas of organic synthesis ranging from the latest developments in enantioselective methodologies, to reviews of updated chemical methods. The volumes are written by experts, who describe their own area of expertise, as well as those of their peers.

Buch. Zustand: Neu. Neuware - One of the mysteries of mammalian reproduction is the physiologic process that determines the length of gestation. The proper timing of birth ensures that the young individual is sufficiently developed to survive and adapt in the extrauterine environment, and that the mother is capable to provide nutrition and protection to the newborn. This volume summarizes new knowledge obtained by many researchers seeking to unravel the compile mechanisms that contribute to the maintenance and termination of pregnancy. The most important common goal of these efforts is to reduce the incidence of preterm birth, which is the leading cause of perinatal morbidity and mortality in numerous countries. Separate chapters are devoted to the best-studied animal models of parturition. In sheep, the fetus is in control of the timing of its own birth, while in avian species, oviposition is evidently determined by the female laying the feritlized egg. In humans and non-human primates, the roles of the fetus and the mother are more balanced, and involve a complicated and poorly understood interplay between the mother, the fetus, and the placenta. Some major aspects of these interactions, such as trophoblast function, myometrial contractility, and the endocrine-paracrine systems, are discussed in further chapters.

Buch. Zustand: Neu. Neuware - Interest in the concept of time has a long history and has been a topic of study for a wide range of investigators. No change can take place without specification of time. While philosophers and physicists have been intrigued by the concept of subjective perception of time and its relationship to real time, natural scientists have been concerned mainly with investigating time as a factor in understanding the behaviour of animals from the migratory habits of birds to the periodical breeding cycles. The immense bulk of temporal perception studies, the variety of approaches, methods of measurement and even terminology has led to a difficulty in reaching a global interpretation of the results.This book aims to give an integrative approach of time sense and to focus the analysis on temporal factors in the processing of movement, trying to link temporal perception studies in the final common pathway, that is motion. To give some clues of human brain integrative processes at higher levels. And, finally, to clarify the neurophysiological substrate of these operations.

Buch. Zustand: Neu. Neuware - Volume XXXV contains six review articles.The first article is a discussion on transverse light patterns in non-linear media, lasers and wide aperture interferometers. The next article deals with the detection and spectroscopic studies of single molecules in transparent solids at low temperature. The isolated spectral line of a single molecule makes it possible to perform basic quantum measurements, and allows probing in unprecedented detail of the surrounding solid matrix. The article also includes some suggestions for future research in this field.The next article reviews interferometric techniques for retrieving multispectral images with a large number of spectral channels. Special attention is paid to the theory of interferometric multispectral imaging which unifies the theories of coherence based image retrieval and spectrum recovery. Various techniques are compared, especially in terms of signal-to-noise-ratio.