Crc press dez 2021 (10 Ergebnisse)

Taschenbuch. Zustand: Neu. Neuware - Developed over previous editions by the Royal College of Surgeons in Ireland to support students attending the three RCSI universities, this convenient handbook provides pragmatic guidance to the principles and practice of surgery that students can expect to encounter during undergraduate studies. Spanning the full range of surgical specialties, information is presented in a convenient and clinically relevant format that takes the students through the patient journey from presenting symptoms and aetiology to investigations, management and follow-up. The text, written as easy-to-read and easy-to-remember bullet lists, is supplemented throughout by tables, management algorithms and colour illustrations. Key Features:¿ Concise - specifically for the undergraduate medical student by a highly experienced team of surgical educators¿ Accessible - bullet text ideal for rapid reference¿ Flexible - for use when on the ward and during finals revision¿ Complete - print book supplemented by video clips, online question and answer material and an image library for the full learning and revision packageThoroughly updated, this fifth edition has enhanced pedagogy and, for the first time, is accompanied by video clips and questions for self-testing. Covering the core surgical knowledge needed to become a safe and competent doctor, the book will be an invaluable companion for clinical placements and during the critical run-up to final examinations.…

Taschenbuch. Zustand: Neu. Neuware - Reliably optimizing a new treatment in humans is a critical first step in clinical evaluation since choosing a suboptimal dose or schedule may lead to failure in later trials. At the same time, if promising preclinical results do not translate into a real treatment advance, it is important to determine this quickly and terminate the clinical evaluation process to avoid wasting resources. Bayesian Designs for Phase I-II Clinical Trials describes how phase I-II designs can serve as a bridge or protective barrier between preclinical studies and large confirmatory clinical trials. It illustrates many of the severe drawbacks with conventional methods used for early-phase clinical trials and presents numerous Bayesian designs for human clinical trials of new experimental treatment regimes.Written by research leaders from the University of Texas MD Anderson Cancer Center, this book shows how Bayesian designs for early-phase clinical trials can explore, refine, and optimize new experimental treatments. It emphasizes the importance of basing decisions on both efficacy and toxicity.…

Taschenbuch. Zustand: Neu. Neuware - Pharmaceutical product development is a multidisciplinary activity involving extensive efforts in systematic product development and optimization in compliance with regulatory authorities to ensure the quality, efficacy and safety of resulting products.Pharmaceutical Product Development equips the pharmaceutical formulation scientist with extensive and up-to-date knowledge of drug product development and covers all steps from the beginning of product conception to the final packaged form that enters the market and lifecycle management thereof.Applications of core scientific principles for product development are also thoroughly discussed in conjunction with the latest approaches involving design of experiment and quality by design with comprehensive illustrations based on practical case studies of several dosage forms.The book presents pharmaceutical product development information in an easy-to-read mode with simplified theories, case studies and guidelines for students, academicians and professionals in the pharmaceutical industry. It is an invaluable resource and hands-on guide covering managerial, regulatory and practical aspects of pharmaceutical product lifecycle management.…

Taschenbuch. Zustand: Neu. Neuware - In today's hyper-competitive, global marketplace, a manufacturing company needs a competitive edge if it is to survive and grow. That edge could be anything from superior manufacturing technology to innovative product design; from patent protection to solid, well-established customer relationships. One competitive edge available to all manufacturers, but realized by only a few, is the ability to accurately measure, control, and optimize costs throughout a product's entire life cycle. The lack of a methodology to engineer cost optimization into every product makes attaining and maintaining profitability all that the more difficult.Cost Engineering provides a means for a manufacturer to achieve and sustain profitability by designing and manufacturing products to specific cost requirements. It incorporates a variety of proven methodologies including cost estimating, cost control, and cost optimization. Features:¿ Describes the components and organization of an effective cost optimization process¿ Provides detailed explanations of cost estimating techniques for many of the most common manufacturing processes¿ Explains the selection and use of appropriate cost allocation methods¿ Presents the fundamentals of cost-based negotiation¿ Includes both proper and improper executions of cost engineering principlesThe details presented in this book are important to design engineers, manufacturing engineers, buyers, accountants, cost estimators, cost optimization specialists, and their managers and provides CEOs, COOs, general managers, product line managers, and plant managers with guidance on improving and sustaining profitability. …

Taschenbuch. Zustand: Neu. Neuware - Atlas of Terrestrial Mammal Limbs is the first comprehensive and detailed anatomy book on a broad phylogenetic and ecological range of mammals. This extraordinary new work features more than 400 photographs and illustrations visualizing the limb musculature of 28 different species. Standardized views of the dissected bodies and concise text descriptions make it easy to compare the anatomy across different taxa. It provides tables of nomenclature and comparative muscle maps (schematic drawings on the origins and insertions of the muscles onto bones) in a diversity of animals. Atlas of Terrestrial Mammal Limbs is a reliable reference and an indispensable volume for all students and professional researchers in biology, paleontology, and veterinary medicine.Key Features: - Provides an overview of the anatomy of the mammalian limb - Includes osteological correlates of the limb muscles - Illustrates anatomy in 2D - Guides dissection - Documents anatomical diversity in mammalian limbs Related Titles:D. L. France. Human and Nonhuman Bone Identification: A Color Atlas. (ISBN 978-1-4200-6286-1)S. N. Byers. Forensic Anthropology Laboratory Manual, 4th Edition (ISBN 978-1-1386-9073-8)S. N. Byers. Introduction to Forensic Anthropology, 5th Edition (ISBN 978-1-1381-8884-6)R. Diogo, et al. Muscles of Chordates: Development, Homologies, and Evolution (ISBN 978-1-1385-7116-7).…

Taschenbuch. Zustand: Neu. Neuware - Apley & Solomon's Concise System of Orthopaedics and Trauma is firmly established as the leading introductory textbook of orthopaedic practice and the principles of fracture and trauma management. Praised in previous editions for the systematic approach, balanced content and easy-to-read style, this fifth edition has been brought fully up to date under the direction of the new and distinguished authorial team, while remaining true to the teaching principles of Alan Apley and his successor Louis Solomon.Key features: - Focused - on diseases and clinical signs with additional detail on anatomy where appropriate - International - enhanced coverage of 'global orthopaedics' reflect the changing pattern of musculoskeletal disease and trauma around the world - Relevant - provides helpful guidance on simple procedures without unnecessary operative detail - Readable - increased emphasis on concise presentation - Current - updates reflect developments in molecular biology, genetics and imaging technology This fifth edition remains the first choice for medical students, trainee surgeons and other health professionals seeking a convenient introduction to this large and complex subject and is a natural precursor to the more detailed coverage offered by its larger parent, Apley & Solomon's System of Orthopaedics and Trauma.…

Taschenbuch. Zustand: Neu. Neuware - The first edition of Bioactive Compounds from Natural Sources was published in a period of renewed attention to biologically active compounds of natural origin. This trend has continued and intensified-natural products are again under the spotlight, in particular for their possible pharmacological applications. Largely focusing on natural products as lead compounds in drug discovery, Bioactive Compounds from Natural Sources, Second Edition: Natural Products as Lead Compounds in Drug Discovery is actually a completely new volume containing surveys of selected recent advances in an interdisciplinary area covering chemistry of natural products, medicinal chemistry, biochemistry, and other related topics.Written by some of the most reputed scientists in the field, this second edition includes new chapters from authors who contributed to the first edition as well as many chapters compiled by new authors. Introducing the reader to strategies and methods in the search for bioactive natural products, this book covers topics including: - Natural sources of bioactive compounds such as aquatic cyanobacteria, filamentous fungi, and tropical plants, - The tremendous potentiality of metabolic engineering of natural products biosynthesis - The contribution of emerging or developing technologies to the study of bioactive natural compounds, namely computational methods and circular dichroism - The potential of natural or natural-derived compounds for specific therapeutic applications: treatment of viral diseases, regulation of hypoxia-inducible factor, antimalarials, modulation of angiogenesis, and antitumor and wound-healing activity - Selected examples of natural product families and related synthetic analogues, namely polyphenols and campthotecins Compiled for researchers and Ph.D. students working in interdisciplinary fields, this book will also be appreciated by readers without a background in chemistry interested in bioactive natural products, their biological and pharmacological properties, and their possible use as chemopreventive or chemotherapeutic agents. Conversely, the biological and pharmacological data and methods are accessible by chemists.…

Taschenbuch. Zustand: Neu. Neuware - To succeed in the lab, it is crucial to be comfortable with the math calculations that are part of everyday work. This accessible introduction to common laboratory techniques focuses on the basics, helping even readers with good math skills to practice the most frequently encountered types of problems. Basic Laboratory Calculations for Biotechnology, Second Edition discusses very common laboratory problems, all applied to real situations. It explores multiple strategies for solving problems for a better understanding of the underlying math. Primarily organized around laboratory applications, the book begins with more general topics and moves into more specific biotechnology laboratory techniques at the end. This book features hundreds of practice problems, all with solutions and many with boxed, complete explanations; plus hundreds of 'story problems' relating to real situations in the lab. Additional features include: - Discusses common laboratory problems with all material applied to real situations - Presents multiple strategies for solving problems help students to better understand the underlying math - Provides hundreds of practice problems and their solutions - Enables students to complete the material in a self-paced course structure with little teacher assistance - Includes hundreds of 'story problems'that relate to real situations encountered in the laboratory.…

Taschenbuch. Zustand: Neu. Neuware - Cutaneous Cryosurgery is an invaluable practical guide for the management of benign, premalignant, and malignant skin lesions. The book provides practitioners with all the information needed to add cryosurgery to their surgical repertoire. For practitioners already using cryosurgery, many pearls are provided to expand the use of cryosurgery for new indications along with helpful tips for the use of cutting-edge cryosurgical equipment.This new edition of an established reference uses an evidence-based approach, including a chapter reviewing the evidence for using cryosurgery to treat viral warts, actinic keratosis, and basal cell carcinoma. It also discusses patient consent, aftercare, side effects, and complications. In addition, the book reviews other low-temperature systems used for therapeutic tissue destruction.With nearly 300 clinical color photographs, the book is an outstanding resource for dermatologists, family physicians, other primary care physicians, nurse practitioners, physician assistants, podiatrists, plastic surgeons, head and neck surgeons, and oculoplastic surgeons alike.…

Buch. Zustand: Neu. Neuware - Basic Laboratory Methods for Biotechnology, Third Edition is a versatile textbook that provides students with a solid foundation to pursue employment in the biotech industry and can later serve as a practical reference to ensure success at each stage in their career. The authors focus on basic principles and methods while skillfully including recent innovations and industry trends throughout. Fundamental laboratory skills are emphasized, and boxed content provides step by step laboratory method instructions for ease of reference at any point in the students' progress. Worked through examples and practice problems and solutions assist student comprehension. Coverage includes safety practices and instructions on using common laboratory instruments.Key Features: - Provides a valuable reference for laboratory professionals at all stages of their careers - Focuses on basic principles and methods to provide students with the knowledge needed to begin a career in the Biotechnology industry - Describes fundamental laboratory skills - Includes laboratory scenario-based questions that require students to write or discuss their answers to ensure they have mastered the chapter content - Updates reflect recent innovations and regulatory requirements to ensure students stay up to date - Tables, a detailed glossary, practice problems and solutions, case studies and anecdotes provide students with the tools needed to master the content. …