Crc press dez 2011 (6 Ergebnisse)

Taschenbuch. Zustand: Neu. Neuware - This Rapid Review is a concise, evidence-based guide to the diagnosis and treatment of rheumatological and musculoskeletal disorders. Covering the basic principles of joint examination and key clinical skills, the book describes more than 100 clinical cases especially chosen to illustrate both commonly occurring and more unusual conditions. Each case presentation replicates a real-life situation in the busy world of a typical clinic and is illustrated with superb quality colour clinical photographs. Following the case presentation, a series of questions are posed to simulate the diagnosis process along with answers to the questions and a final diagnosis. Tables with lab values supplement the photos and text. Following the case presentations, the book discusses the top ten rheumatological disease categories including rheumatoid arthritis, spondyloarthropathies, lupus, vascultis and other miscellaneous conditions. The book will become an essential 'go to' text for all trainee rheumatologists and general medical practitioners, including specialist nurses, manual therapists and related health professionals.Key Features: - Presents clinicians with a series of both common and challenging case presentations that depict the investigation and management of patients with rheumatological and musculoskeletal conditions - Covers basic principles as well as the necessary clinical skills - Includes more than 100 case presentations with numerous colour illustrations of the highest quality - Features a concise format ideal for rapid revision and exam preparation.…

Taschenbuch. Zustand: Neu. Neuware - Whatever your type of business, this practical handbook will help you to manage your premises effectively. Whether you are a tenant or an owner-occupier, it will enable you to take an informed approach to commercial property, helping you to negotiate successful transactions, deal with ongoing management issues effectively and get the most from advisers and agents. The handbook takes a practical approach using worked examples and checklists. It provides a step-by-step guide to all the stages of occupation with comprehensive coverage of all the relevant legal and technical information, including: - strategic property management - financial analysis and decision making - negotiating strategy - valuation - accounting - tax and business rates - acquisitions - purchase and lease terms - rent reviews - service charges - insurance - repairs alterations and use - planning and environmental issues - disposal of surplus space - lease expiries and renewals - compulsory purchase.…

Taschenbuch. Zustand: Neu. Neuware - Accurate predictions of storm surge are of importance in many coastal areas in the world to avoid and mitigate its destructive impacts. For this purpose the physically-based (process) numerical models are typically utilized. However, in data-rich cases, one may use data-driven methods aiming at reconstructing the internal patterns of the modelled processes and relationships between the observed descriptive variables. This book focuses on data-driven modelling using methods of nonlinear dynamics and chaos theory. First, some fundamentals of physical oceanography, nonlinear dynamics and chaos, computational intelligence and European operational storm surge models are covered. After that a number of improvements in building chaotic models are presented: nonlinear time series analysis, multi-step prediction, phase space dimensionality reduction, techniques dealing with incomplete time series, phase error correction, finding true neighbours, optimization of chaotic model, data assimilation and multi-model ensemble prediction. The major case study is surge prediction in the North Sea, with some tests on a Caribbean Sea case. The modelling results showed that the enhanced predictive chaotic models can serve as an efficient tool for accurate and reliable short and mid-term predictions of storm surges in order to support decision-makers for flood prediction and ship navigation.…

Buch. Zustand: Neu. Neuware - Richly illustrated in color, Statistics and Data Analysis for Microarrays Using R and Bioconductor, Second Edition provides a clear and rigorous description of powerful analysis techniques and algorithms for mining and interpreting biological information. Omitting tedious details, heavy formalisms, and cryptic notations, the text takes a hands-on, example-based approach that teaches students the basics of R and microarray technology as well as how to choose and apply the proper data analysis tool to specific problems.New to the Second EditionCompletely updated and double the size of its predecessor, this timely second edition replaces the commercial software with the open source R and Bioconductor environments. Fourteen new chapters cover such topics as the basic mechanisms of the cell, reliability and reproducibility issues in DNA microarrays, basic statistics and linear models in R, experiment design, multiple comparisons, quality control, data pre-processing and normalization, Gene Ontology analysis, pathway analysis, and machine learning techniques. Methods are illustrated with toy examples and real data and the R code for all routines is available on an accompanying downloadable resource.With all the necessary prerequisites included, this best-selling book guides students from very basic notions to advanced analysis techniques in R and Bioconductor. The first half of the text presents an overview of microarrays and the statistical elements that form the building blocks of any data analysis. The second half introduces the techniques most commonly used in the analysis of microarray data.…

Buch. Zustand: Neu. Neuware - The basal ganglia are involved in complex brain functions, from voluntary movement control to learning and reward processing, and they are implicated in numerous neurological and psychiatric disorders. Information from the cerebral cortex and thalamus is conveyed to basal ganglia nuclei via glutamate release, while dopamine from the midbrain is released in close proximity to glutamate. At the heart of both function and dysfunction of basal ganglia circuits is the interaction of these two neurotransmitters, dopamine and glutamate.Elucidating the relationship between their molecular and cellular effects and behavioural significance has been challenging, but in the past 5-10 years, improved labeling, imaging, recording, and genetic manipulation approaches have yielded new information on how dopamine and glutamate interact to generate the circuit activity underpinning basal ganglia function. Dopamine-Glutamate Interactions in the Basal Ganglia synthesizes this recent research from the level of receptor molecules all the way to complex behaviours and disease. Current insights from research on individual neurons and synapses, detailed circuit analysis, and learning and action functions of the basal ganglia are presented against a historical perspective. The book also discusses compromised dopamine-glutamate interaction in disorders of basal ganglia function, including Parkinson's disease, Huntington's disease, and drug addiction.…

Buch. Zustand: Neu. Neuware - With multicore processors now in every computer, server, and embedded device, the need for cost-effective, reliable parallel software has never been greater. By explaining key aspects of multicore programming, Fundamentals of Multicore Software Development helps software engineers understand parallel programming and master the multicore challenge. Accessible to newcomers to the field, the book captures the state of the art of multicore programming in computer science. It covers the fundamentals of multicore hardware, parallel design patterns, and parallel programming in C++, .NET, and Java. It also discusses manycore computing on graphics cards and heterogeneous multicore platforms, automatic parallelization, automatic performance tuning, transactional memory, and emerging applications.As computing power increasingly comes from parallelism, software developers must embrace parallel programming. Written by leaders in the field, this book provides an overview of the existing and up-and-coming programming choices for multicores. It addresses issues in systems architecture, operating systems, languages, and compilers.…