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Buch. Zustand: Neu. Neuware -In September 1997, the Working Week on Resolution of Singularities was held at Obergurgl in the Tyrolean Alps. Its objective was to manifest the state of the art in the field and to formulate major questions for future research. The four courses given during this week were written up by the speakers and make up part I of this volume. They are complemented in part II by fifteen selected contributions on specific topics and resolution theories. The volume is intended to provide a broad and accessible introduction to resolution of singularities leading the reader directly to concrete research problems.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 628 pp. Englisch.

Buch. Zustand: Neu. Neuware -Gene therapy for inflammatory diseases is a new , burgeoning field ofmedicine. Edited by the undisputed pioneers of this area of researchthis volume is the first devoted to its topic. It contains thirteenchapters, each written by leaders in their respective fields, thatsummarize the state of the art in developing novel, gene basedtreatments for inflammatory diseases. As well as providing anintroduction to the basic concepts of gene therapy and the use of nakedDNA approaches, the book describes the advances that have been made inapplying them to arthritis, lupus, multiple sclerosis, diabetesSjogren`s syndrome and transplantation.One chapter is devoted todiscussing the first human clinical trials that apply gene therapy tothe treatment of an inflammatory disease. As well as providing noveltherapeutic approaches, gene therapy facilitates the development of newand improved animal models of disease; a chapter describing theseadvances is also included. As an up-to-date, timely book written by th 276 pp. Englisch.

Buch. Zustand: Neu. Neuware -Over the past ten years, a number of cytokines and growth factors haveproven to be as effective therapeutics. While these products havecertainly established recombinant biologics as a major pharmaceuticalgrowth sector, the continued interest in this class of drugs arises fromthe fact that today we have a far better understanding of the humanimmune response, both at a cellular and molecular level.This has resulted in a more methodical characterisation of these factorswhich has given clinical researchers an opportunity to plan Phase 1clinical trials that can provide substantial information on the activityof the cytokine in humans. Currently, a great deal of effort is alsobeing channelled into identifying cytokines from the various DNAdatabases.Our major objective for this book is to profile cytokines that have beenrecently identified. The therapeutic potential of these cytokines basedon their known properties will be discussed by the authors. The main aimof this book is to provide.Springer Nature c/o IBS, Benzstrasse 21, 48619 Heek 156 pp. Englisch.