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Verlag: Berlin, Springer, 2009
ISBN 10: 3540690360ISBN 13: 9783540690368
Anbieter: Antiquariat Bookfarm, Löbnitz, Deutschland
Buch
Hardcover. 331 S. Ehem. Bibliotheksexemplar mit Signatur und Stempel. GUTER Zustand, ein paar Gebrauchsspuren. Ex-library with stamp and library-signature. GOOD condition, some traces of use. 9783540690368 Sprache: Englisch Gewicht in Gramm: 550.
Verlag: Springer Berlin Heidelberg, 2014
ISBN 10: 3642435947ISBN 13: 9783642435942
Anbieter: AHA-BUCH GmbH, Einbeck, Deutschland
Buch
Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - reviews. The SAR data are discussed in light of the structural information available for each agent. The second chapter focuses on the total synthesis of the marine sponge-derived polyketide discodermolide. A comprehensive survey of the synthetic chemistry efforts of several groups over a 14-year period is provided together with a compa- son of the different approaches. The third chapter describes a comprehensive study of the mechanisms of activity of microtubules stabilizing drugs. Thermodynamic, kinetic, structural and fu- tional data on microtubules stabilizing drugs are discussed in an interdisciplinary manner to generate a time-resolved picture of the interaction of the drugs with different tubulin forms. The fourth and fifth chapters review the efforts and achievements made in the characterization of the structure of the complexes of tubulin with microtubules stabilizing agents by NMR (Chapter 4) and EM (Chapter 5). Especially evident is the discrepancy of the results obtained for epothilones, where the two techniques deliver radically different structures of the bound drug. Both NMR and EM models are, however, able to explain a consistent set of SAR data. The authors of the two chapters discuss critically the advantages and limitations of each methodology.
Verlag: Springer, 2009
ISBN 10: 3642435947ISBN 13: 9783642435942
Anbieter: Anybook.com, Lincoln, Vereinigtes Königreich
Buch
Zustand: Good. Volume 286. This is an ex-library book and may have the usual library/used-book markings inside.This book has soft covers. Clean from markings. In good all round condition. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,650grams, ISBN:9783642435942.
Verlag: Springer, 2009
ISBN 10: 3540690360ISBN 13: 9783540690368
Anbieter: Studibuch, Stuttgart, Deutschland
Buch
hardcover. Zustand: Sehr gut. 342 Seiten; 9783540690368.2 Sprache: Deutsch Gewicht in Gramm: 1.