Tight junctions (35 Ergebnisse)

Zustand: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.

Zustand: New. pp. xi + 224 48 Illus. (2 Col.).

Taschenbuch. Zustand: Neu. Analysis of tight junctions and chemical synapse in Nervous System | Tight junctions and chemical synapse structure and function in the Nervous System of human beings | Jose O'Daly | Taschenbuch | Englisch | LAP Lambert Academic Publishing | EAN 9786204203935 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu.…

Hardcover. Zustand: Brand New. 262 pages. 11.00x8.50x0.63 inches. In Stock.

Hardcover. Zustand: Brand New. 265 pages. 11.00x8.50x11.00 inches. In Stock.

Zustand: New. In English.

Zustand: New. In English.

Zustand: New. In English.

Buch. Zustand: Neu. Neuware - Tight junctions (TJ) close the gap between endothelial and epithelial cells against undesirable passage of water and solutes. The major protein families of the TJs include junctional adhesion molecules (JAM), claudins, angulins, and TJ-associated MARVEL proteins such as tricellulin and occludin. The majority of these proteins are related to the cytoskeleton through adapters such as zonula occludens (ZO) proteins. TJ proteins not only act as barriers but some of them also create water channels or paracellular ion channels. They are engaged in a variety of processes aside from barrier and channel functions. They may act as pathogen receptors and mediate immunological responses. TJ proteins are involved in a variety of inflammatory disorders as well as bacterial infections. They act as targets in the diagnostics and treatment of cancer tumor and they can also facilitate epithelial-mesenchymal transition, enabling metastasis and tumorigenesis. This book provides significant information to help develop a good understanding of tight junctions and its functions. It will serve as a reference to a broad spectrum of readers.…

Taschenbuch. Zustand: Neu. Tight Junctions | Lorenza González-Mariscal | Taschenbuch | Molecular Biology Intelligence Unit | xi | Englisch | 2010 | Springer | EAN 9781441941152 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu. …

Taschenbuch. Zustand: Neu. Tight Junctions in Cancer Metastasis | Tracey A. Martin (u. a.) | Taschenbuch | viii | Englisch | 2015 | Springer | EAN 9789400798069 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.…

Buch. Zustand: Neu. Neuware - Tight junctions (TJ) close the gap between endothelial and epithelial cells against undesirable passage of water and solutes. The major protein families of the TJs include junctional adhesion molecules (JAM), claudins, angulins, and TJ-associated MARVEL proteins such as tricellulin and occludin. The majority of these proteins are related to the cytoskeleton through adapters such as zonula occludens (ZO) proteins. TJ proteins not only act as barriers but some of them also create water channels or paracellular ion channels. They are engaged in a variety of processes aside from barrier and channel functions. They may act as pathogen receptors and mediate immunological responses. TJ proteins are involved in a variety of inflammatory disorders as well as bacterial infections. They act as targets in the diagnostics and treatment of cancer tumor and they can also facilitate epithelial-mesenchymal transition, enabling metastasis and tumorigenesis. This book provides significant information to help develop a good understanding of tight junctions and its functions. It will serve as a reference to a broad spectrum of readers.…

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - There has been a dramatic increase in knowledge of tight junctions in the past decade. The molecular structure of tight junctions, cellular functions and the pathophysiological roles of tight junctions are becoming clear. Of the most important functions, the role of the cellular structure in cancer spread and drug delivery are increasingly realised. It is now clear that there are fundamental changes to tight junctions during the process of cancer development. Tight junctions are also critical to the metastatic process of cancer cells. The cellular structure is also crucial in drug therapies, namely, the permeability and bioavailability of the drugs, penetration of barriers such as the blood brain barrier. This current volume aims to summarise the current knowledge of tight junctions, their role in cancer and cancer metastasis and is of interest to scientists and clinicians.…

Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - There has been a dramatic increase in knowledge of tight junctions in the past decade. The molecular structure of tight junctions, cellular functions and the pathophysiological roles of tight junctions are becoming clear. Of the most important functions, the role of the cellular structure in cancer spread and drug delivery are increasingly realised. It is now clear that there are fundamental changes to tight junctions during the process of cancer development. Tight junctions are also critical to the metastatic process of cancer cells. The cellular structure is also crucial in drug therapies, namely, the permeability and bioavailability of the drugs, penetration of barriers such as the blood brain barrier. This current volume aims to summarise the current knowledge of tight junctions, their role in cancer and cancer metastasis and is of interest to scientists and clinicians.…

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - ight junctions (TJs) are cell-ceil adhesion belts that encircle epithelial and endothelial cells at the limit between the apical and the lateral Tmembrane. These junctions are crucial for the establishment of separate compartments in multicellular organisms and for the exchange of substances between the internal milieu and the external environment. The perception of TJs has changed over the years. From being regarded as static paracellular seals, they have come to be perceived as dynamic structures that adjust their morphol ogy and function in response to physiological, pharmacological and pathologi cal challenges. The roles that TJs play in epithelial and endothelial cells has also widened, and nowadays this structure is regarded not only as a fence that limits within the membrane, the movement of proteins and lipids between the apical and basolateral membranes, or as a gate that regulates in a size and charge selec tive manner the transit of ion and molecules through the paracellular pathway, but also as a structure integrated by molecules that participate in the control of cell proliferation. These observations highlight the importance of understand ing TJ physiology in order to develop effective strategies for the treatment of pathological conditions such as cancer and autoimmune diseases. This broader perception of TJs is reflected in all the chapters of the book and has been attained thanks to the identification in recent years of a wide array of proteins that constitute TJs in epithelial and endothelial cells as well as in central nervous system myelin.…

Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - ight junctions (TJs) are cell-ceil adhesion belts that encircle epithelial and endothelial cells at the limit between the apical and the lateral Tmembrane. These junctions are crucial for the establishment of separate compartments in multicellular organisms and for the exchange of substances between the internal milieu and the external environment. The perception of TJs has changed over the years. From being regarded as static paracellular seals, they have come to be perceived as dynamic structures that adjust their morphol ogy and function in response to physiological, pharmacological and pathologi cal challenges. The roles that TJs play in epithelial and endothelial cells has also widened, and nowadays this structure is regarded not only as a fence that limits within the membrane, the movement of proteins and lipids between the apical and basolateral membranes, or as a gate that regulates in a size and charge selec tive manner the transit of ion and molecules through the paracellular pathway, but also as a structure integrated by molecules that participate in the control of cell proliferation. These observations highlight the importance of understand ing TJ physiology in order to develop effective strategies for the treatment of pathological conditions such as cancer and autoimmune diseases. This broader perception of TJs is reflected in all the chapters of the book and has been attained thanks to the identification in recent years of a wide array of proteins that constitute TJs in epithelial and endothelial cells as well as in central nervous system myelin.…

Zustand: New. In English.

Zustand: New. In English.

Zustand: New. In English.

Taschenbuch. Zustand: Neu. Tight Junctions | Lorenza González-Mariscal | Taschenbuch | xii | Englisch | 2023 | Springer | EAN 9783030972066 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.

Paperback. Zustand: Brand New. reprint edition. 235 pages. 9.00x6.00x0.57 inches. In Stock.

Hardcover. Zustand: Brand New. 1st edition. 224 pages. 9.25x6.25x0.50 inches. In Stock.

Hardcover. Zustand: Brand New. 1st edition. 313 pages. 9.25x6.25x1.00 inches. In Stock.

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This volume explores the dynamic topic of tight junctions. The book focuses on tight junctions' role in sealing adjacent epithelial cells in a narrow band just beneath their apical surface. The book explains how tight junctions consist of a network of claudins and other proteins, and delves into how they hold cells together and form functional and protective barriers, regulating the passage of molecules and ions through the space between cells.The book opens with a discussion of the evolution of research on tight junctions, discussing a range of primary areas of growth, including the current knowledge on the particular physiological function of different claudins due to the development of an array of knock out mice.The chaptersalso explore in-depth studies of tight junctions in specific tissues (gut, lung and endothelia).This book offers a comprehensive understanding on post-translational modifications of occludin and its impact on tight junction function, as well as the molecular composition and function of tricellular tight junctions. This volume isparticularly relevant to students and scientists in neuroscience, cell biology, physiology, cell differentiation, and cancer research.…

Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This volume explores the dynamic topic of tight junctions. The book focuses on tight junctions' role in sealing adjacent epithelial cells in a narrow band just beneath their apical surface. The book explains how tight junctions consist of a network of claudins and other proteins, and delves into how they hold cells together and form functional and protective barriers, regulating the passage of molecules and ions through the space between cells.The book opens with a discussion of the evolution of research on tight junctions, discussing a range of primary areas of growth, including the current knowledge on the particular physiological function of different claudins due to the development of an array of knock out mice.The chaptersalso explore in-depth studies of tight junctions in specific tissues (gut, lung and endothelia).This book offers a comprehensive understanding on post-translational modifications of occludin and its impact on tight junction function, as well as the molecular composition and function of tricellular tight junctions. This volume isparticularly relevant to students and scientists in neuroscience, cell biology, physiology, cell differentiation, and cancer research.…

Taschenbuch. Zustand: Neu. Tight Junctions in Inflammation and Cancer | Ajaz A. Bhat (u. a.) | Taschenbuch | xiii | Englisch | 2024 | Springer | EAN 9789819924172 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.…

Zustand: New. In English.

Zustand: Hervorragend. Zustand: Hervorragend | Seiten: 348 | Sprache: Englisch | Produktart: Bücher | This volume explores the dynamic topic of tight junctions. The book focuses on tight junctions' role in sealing adjacent epithelial cells in a narrow band just beneath their apical surface. The book explains how tight junctions consist of a network of claudins and other proteins, and delves into how they hold cells together and form functional and protective barriers, regulating the passage of molecules and ions through the space between cells. The book opens with a discussion of the evolution of research on tight junctions, discussing a range of primary areas of growth, including the current knowledge on the particular physiological function of different claudins due to the development of an array of knock out mice. The chapters also explore in-depth studies of tight junctions in specific tissues (gut, lung and endothelia). This book offers a comprehensive understanding on post-translational modifications of occludin and its impact on tight junction function, as well as the molecular composition and function of tricellular tight junctions. This volume is particularly relevant to students and scientists in neuroscience, cell biology, physiology, cell differentiation, and cancer research.…

Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This book provides an updated account of tight junctions of different epithelia and endothelia and addresses their anatomy, biochemistry, physiology, synthesis, assembly, and modulation. It also discusses the relationship between molecular structure, function, regulation, posttranslational modifications of tight junction proteins and their role in gut microbiota maintenance, epithelial-mesenchymal transition, and intestinal barrier dysfunction-associated disorders important for the progression of human cancers. This book presents the pathological alterations of tight junctions at the blood-brain barrier that intensify or even initiate neurological dysfunction. Further, it reviews the significance of tight junctions and tight junction proteins in cancer development, infectious diseases, allergic reactions, and autoimmune disorders. Lastly, it highlights strategies for modulating tight junctions to enhance drug availability and organ deposition. This book is immensely useful for basic, translational, clinical, and interdisciplinary cancer researchers, practicing oncologists, and immunologists.…

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This book provides an updated account of tight junctions of different epithelia and endothelia and addresses their anatomy, biochemistry, physiology, synthesis, assembly, and modulation. It also discusses the relationship between molecular structure, function, regulation, posttranslational modifications of tight junction proteins and their role in gut microbiota maintenance, epithelial-mesenchymal transition, and intestinal barrier dysfunction-associated disorders important for the progression of human cancers. This book presents the pathological alterations of tight junctions at the blood-brain barrier that intensify or even initiate neurological dysfunction. Further, it reviews the significance of tight junctions and tight junction proteins in cancer development, infectious diseases, allergic reactions, and autoimmune disorders. Lastly, it highlights strategies for modulating tight junctions to enhance drug availability and organ deposition. This book is immensely useful for basic, translational, clinical, and interdisciplinary cancer researchers, practicing oncologists, and immunologists.…