Techniques prion research (10 Ergebnisse)
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Zustand: New. There is an acceleration in prion disease research because of the spread of mad cow disease. This book covers in vitro, cellular, and animal models adapted for the study of TSEs. It includes bio-saftey procedures. Editor(s): Lehmann, Sylvain; Grassi, Jacques. Series: Methods and Tools in Biosciences and Medicine. N…um Pages: 221 pages, 8 black & white tables, biography. BIC Classification: MJN. Category: (P) Professional & Vocational. Dimension: 254 x 178 x 12. Weight in Grams: 448. . 2004. Softcover reprint of the original 1st ed. 2004. Paperback. . . . . Books ship from the US and Ireland.
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Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Prion diseases, also known as Transmissible Spongiform Encephalopathies (TSEs), exist in both humans (Creutzfeldt-Jakob disease (CJD)) and animals (scrapie, bovine spongiform encephalopathy (BSE), chronic wasting disease) and have the unique property… of being infectious, sporadic or genetic in origin.Although the precise nature of the infectious agent responsible for TSEs is not definitely identified, it is now clearly demonstrated that a protein named PrP (for Prion Protein) plays a critical role in the transmission and pathogenesis of TSEs.This book provides the general description as well as the details of the techniques currently used for the study of prion diseases. Taking into account the pivotal role played by PrP it is not surprising that many Chapters of this book deal with the purification, the detection and the characterization of the different forms of this protein. In addition, in vitro, cellular and animal models specifically adapted to the study of TSEs, as well as bio-safety procedures are described. Each Chapter is written by scientists involved for many years in their respective domain of prion biology who give the best of their knowledge in this technical document. This volume is a very useful tool for any laboratory which recently decided to contribute to the study of TSEs as well as for teams already engaged in this field for many years but interested in extending their technical capacity toward new methods.Features:Purification of PrPC and the Pathological Isoform of Prion Protein (PrPsc or PrP-res)Animal Models of TSEsCell Culture Models of TSEsPrPsc ImmunohistochemistryWestern Immunoblotting TechniquesAntibody Production and ELISATSE Strain Typing in MiceBiosafety and Decontamination ProceduresCell-free Conversion of Prion ProteinsCytotoxicity of PrP PeptidesCyclic Amplification of Prion Protein MisfoldingOf interest to:Researchers and clinicians in the fields of cell biology, biomedicine, neuroscience/neuropathology, veterinary medicine and biochemistry.
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Taschenbuch. Zustand: Neu. Techniques in Prion Research | Jacques Grassi (u. a.) | Taschenbuch | x | Englisch | 2004 | Birkhäuser Basel | EAN 9783764322243 | Verantwortliche Person für die EU: Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin, juergen[dot]hartmann[at]springer[dot]com | An…bieter: preigu.
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Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Prion diseases, also known as Transmissible Spongiform Encephalopathies (TSEs), exist in both humans (Creutzfeldt-Jakob disease (CJD)) and animals (scrapie, bovine spongiform encephalopathy (BSE), chronic wasting disease) and have the unique property of bei…ng infectious, sporadic or genetic in origin.Although the precise nature of the infectious agent responsible for TSEs is not definitely identified, it is now clearly demonstrated that a protein named PrP (for Prion Protein) plays a critical role in the transmission and pathogenesis of TSEs.This book provides the general description as well as the details of the techniques currently used for the study of prion diseases. Taking into account the pivotal role played by PrP it is not surprising that many Chapters of this book deal with the purification, the detection and the characterization of the different forms of this protein. In addition, in vitro, cellular and animal models specifically adapted to the study of TSEs, as well as bio-safety procedures are described. Each Chapter is written by scientists involved for many years in their respective domain of prion biology who give the best of their knowledge in this technical document. This volume is a very useful tool for any laboratory which recently decided to contribute to the study of TSEs as well as for teams already engaged in this field for many years but interested in extending their technical capacity toward new methods.Features:Purification of PrPC and the Pathological Isoform of Prion Protein (PrPsc or PrP-res)Animal Models of TSEsCell Culture Models of TSEsPrPsc ImmunohistochemistryWestern Immunoblotting TechniquesAntibody Production and ELISATSE Strain Typing in MiceBiosafety and Decontamination ProceduresCell-free Conversion of Prion ProteinsCytotoxicity of PrP PeptidesCyclic Amplification of Prion Protein MisfoldingOf interest to:Researchers and clinicians in the fields of cell biology, biomedicine, neuroscience/neuropathology, veterinary medicine and biochemistry.
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Hardcover. Zustand: Brand New. 1st edition. 219 pages. German language. 9.50x6.75x0.50 inches. In Stock.
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Zustand: New. 2004. Hardcover. . . . . . Books ship from the US and Ireland.
