removal diffusible substances circulating von abel john (2 Ergebnisse)

Taschenbuch. Zustand: Neu. Neuware.

J. Pharm. exp. Ther., 5/3. - 1914, pp.275-316, orig. Broschur. PRECURSOR TO THE MODERN DAY DIALYSIS MACHINE! Rare Offprint "Reprinted from The Journal of Pharmacology and Experimental Therapeutics."! "Received for publication, December 18, 1913". "Together with Leonard George Rowntree (1883-1859) and Benjamin Bernard Turner 1971-1945), John Jacob Abel (1857-1938) devised what they called a "vividiffusion" apparatus, consisting of a series of tubes surrounded by fluid. They first demonstrated the apparatus at the Physiological Congress in Groningen in 1914. By allowing arterial blood to enter at one end of the connection, and later return to circulation through the venous connection after dialysis, they were able to demonstrate the existence of free amino acids in blood. By isolating these amino acids from blood circulation, Abel conducted various subsequent researches on the structure of proteins in the blood. Not only did Abel use the apparatus for his research work, he also realized the great clinical potential such dialysis machine would have on managing the damaging effects of renal failure. The vividiffusion apparatus Abel devised is the precursor to the modern day dialysis machine." He summarized his work in a paper published in 1913, "On the Removal of Diffusable Substances from the Circulating Blood by Means of Dialysis" by Transfusion Science. John Jacob Abel (1857-1938) was an American biochemist and pharmacologist. He established the pharmacology department at Johns Hopkins University School of Medicine in 1893, and then became America's first full-time professor of pharmacology. During his time at Hopkins, he made several important medical advancements, especially in the field of hormone extraction. In addition to his laboratory work, he founded several significant scientific journals such as the Journal of Biological Chemistry and the Journal of Pharmacology and Experimental Therapeutics. Garrison & Morton No. 741.2.