Verlag: LAP LAMBERT Academic Publishing Nov 2011, 2011
ISBN 10: 3846540528 ISBN 13: 9783846540527
Sprache: Englisch
Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland
Taschenbuch. Zustand: Neu. Neuware -Alopecia areata is a T-cell mediated autoimmune disease which mainly affects the anagen stage hair follicles, the most effective way of treating alopecia areata is the application of contact sensitizers which induces a mild chronic eczema (delayed type hypersensitivity). The curative effect of chronic eczema relies on the expansion of myeloid derived suppressor cells (MDSC) which can suppress the autoreactive T-cells and induces apoptosis of these via mitochondrial apoptotic pathway. Alternatively, a blockade of accessory molecules in T-cell activation could possibly be of therapeutic benefit. CD44 and CD49d being candidate accessory molecules since association of CD44 with CD49d plays an important role in homing of lymphocytes and blockade of these bystander pathways could be a therapeutic approach in alopecia areata.Books on Demand GmbH, Überseering 33, 22297 Hamburg 216 pp. Englisch.
Verlag: LAP LAMBERT Academic Publishing, 2011
ISBN 10: 3846540528 ISBN 13: 9783846540527
Sprache: Englisch
Anbieter: Revaluation Books, Exeter, Vereinigtes Königreich
EUR 148,60
Anzahl: 1 verfügbar
In den WarenkorbPaperback. Zustand: Brand New. 216 pages. 8.66x5.91x0.49 inches. In Stock.
Verlag: LAP LAMBERT Academic Publishing, 2011
ISBN 10: 3846540528 ISBN 13: 9783846540527
Sprache: Englisch
Anbieter: Revaluation Books, Exeter, Vereinigtes Königreich
EUR 158,29
Anzahl: 1 verfügbar
In den WarenkorbPaperback. Zustand: Brand New. 216 pages. 8.66x5.91x0.49 inches. In Stock.