Non protein coding rnas (13 Ergebnisse)
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Taschenbuch. Zustand: Neu. NON-PROTEIN-CODING RNAS MEDIATE FINE-TUNED GENE EXPRESSION | VOLUME ONE: REGULATORY ROLES OF NATURAL ANTISENSE TRANSCRIPTS | Mohammad Ali Faghihi | Taschenbuch | 128 S. | Englisch | 2010 | LAP LAMBERT Academic Publishing | EAN 9783838323947 | Verantwortliche Person für die EU: BoD - Books on Demand, In… de Tarpen 42, 22848 Norderstedt, info[at]bod[dot]de | Anbieter: preigu.
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Zustand: Sehr gut. Zustand: Sehr gut | Seiten: 412 | Sprache: Englisch | Produktart: Bücher | The 2006 Nobel Prize in Physiology or Medicine was awarded to the discoverers of RNA interference, Andrew Fire and Craig Mello. This prize, which follows ¿RNA¿ Nobels for splicing and RNA catalysis, highlights just one class of recently… discovered non-protein coding RNAs. Remarkably, non-coding RNAs are thought to outnumber protein coding genes in mammals by perhaps as much as four-fold. In fact, it appears that the complexity of an organism correlates with the fraction of its genome devoted to non-protein coding RNAs. Essential biological processes as diverse as cell differentiation, suppression of infecting viruses and parasitic tra- posons, higher-level organization of eukaryotic chromosomes, and gene expression are found to be largely directed by non-protein coding RNAs. Currently, bioinformatic, high-throughput sequencing, and biochemical approaches are identifying an increasing number of these RNAs. Unfortunately, our ability to characterize the molecular details of these RNAs is significantly lacking. The biophysical study of these RNAs is an emergent field that is unraveling the molecular underpinnings of how RNA fulfills its multitude of roles in sustaining cellular life. The resulting understanding of the physical and chemical processes at the molecular level is critical to our ability to harness RNA for use in biotechnology and human therapy, a prospect that has recently spawned a multi-billion dollar industry.
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Taschenbuch. Zustand: Neu. Non-Protein Coding RNAs | Nils Walter (u. a.) | Taschenbuch | xi | Englisch | 2010 | Springer | EAN 9783642089800 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.
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Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This book explores the intricate world of epigenetics and its pivotal role in precision medicine and the identification of epigenetic biomarkers for patient stratification, highlighting the importance of non-coding RNAs (ncRNAs), DNA methylation and histone… modifications. The book discusses various epigenetic drugs, such as HDAC inhibitors and DNA methyltransferase inhibitors, targeting specific pathways to provide new therapeutic avenues.An important part in each chapter is dedicated to in silico analysis in epigenetics, including genome-wide association studies to identify correlations between genetic variations and epigenetic changes. It also covers computational models that simulate the effects of epigenetic modifications on cellular behaviour, providing insights into clinical trials with prodrugs in various types of cancer.The book focuses on the crucial role of gut microorganisms in hormone metabolism, synthesis of bioactive compounds and maintenance of the immune response, influencing endocrine homeostasis. It explores the interplay between gut microbiota, ncRNAs and endocrine regulation, focusing on endocrine-related cancers. The impact of the gut microbiome on host health through epigenetic changes is examined in depth, with a particular focus on the role of ncRNAs in host-microbe interactions.Advances in liver cell epigenetics are discussed, showing how epigenetic changes contribute to liver disorders and the potential for epigenetic-based therapeutic approaches. The book also addresses the impact of epigenetic modifications in colorectal cancer and breast cancer highlighting their role in inflammation, vascular function and lipid metabolism.Special attention is given to the importance of epigenetics and precision medicine in the context of rare cancers, blood disorders and immune-related diseases. The book reviews current literature, clinical trials and case studies, providing an overview of therapeutic potentials and innovations. It emphasises the importance of patient-centred approaches, collaborative research networks and ethical considerations in advancing the field.This book synthesises findings on the contributions of epigenetics and precision medicine to the treatment of various diseases, advocating interdisciplinary research and continuing education to improve patient care and outcomes.
Sprache: Englisch
Verlag: Springer Berlin Heidelberg, Springer Berlin Heidelberg 2008
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Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The 2006 Nobel Prize in Physiology or Medicine was awarded to the discoverers of RNA interference, Andrew Fire and Craig Mello. This prize, which follows 'RNA' Nobels for splicing and RNA catalysis, highlights just one class of recently discovered non-prote…in coding RNAs. Remarkably, non-coding RNAs are thought to outnumber protein coding genes in mammals by perhaps as much as four-fold. In fact, it appears that the complexity of an organism correlates with the fraction of its genome devoted to non-protein coding RNAs. Essential biological processes as diverse as cell differentiation, suppression of infecting viruses and parasitic tra- posons, higher-level organization of eukaryotic chromosomes, and gene expression are found to be largely directed by non-protein coding RNAs. Currently, bioinformatic, high-throughput sequencing, and biochemical approaches are identifying an increasing number of these RNAs. Unfortunately, our ability to characterize the molecular details of these RNAs is significantly lacking. The biophysical study of these RNAs is an emergent field that is unraveling the molecular underpinnings of how RNA fulfills its multitude of roles in sustaining cellular life. The resulting understanding of the physical and chemical processes at the molecular level is critical to our ability to harness RNA for use in biotechnology and human therapy, a prospect that has recently spawned a multi-billion dollar industry.
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Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The 2006 Nobel Prize in Physiology or Medicine was awarded to the discoverers of RNA interference, Andrew Fire and Craig Mello. This prize, which follows 'RNA' Nobels for splicing and RNA catalysis, highlights just one class of recently discovered no…n-protein coding RNAs. Remarkably, non-coding RNAs are thought to outnumber protein coding genes in mammals by perhaps as much as four-fold. In fact, it appears that the complexity of an organism correlates with the fraction of its genome devoted to non-protein coding RNAs. Essential biological processes as diverse as cell differentiation, suppression of infecting viruses and parasitic tra- posons, higher-level organization of eukaryotic chromosomes, and gene expression are found to be largely directed by non-protein coding RNAs. Currently, bioinformatic, high-throughput sequencing, and biochemical approaches are identifying an increasing number of these RNAs. Unfortunately, our ability to characterize the molecular details of these RNAs is significantly lacking. The biophysical study of these RNAs is an emergent field that is unraveling the molecular underpinnings of how RNA fulfills its multitude of roles in sustaining cellular life. The resulting understanding of the physical and chemical processes at the molecular level is critical to our ability to harness RNA for use in biotechnology and human therapy, a prospect that has recently spawned a multi-billion dollar industry.
From Epigenetics-to-precision E2p: Non-protein Coding Rnas Ncrnas a Step-toward Precision Medicine
M. Hamdy , Nadia (Editor)/ S. Sultan, Ahmed (Editor)/ Kennedy, John Frederick (Editor)
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Non-Protein Coding RNAs
Batey, Robert T. (Editor) / Walter, Nils (Editor) / Woodson, Sarah A. (Editor)
- Softcover
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Paperback. Zustand: Brand New. 409 pages. 9.00x6.00x0.97 inches. In Stock.
