Zustand: good. Gently used with minimal wear on the corners and cover. A few pages may contain light highlighting or writing, but the text remains fully legible. Dust jacket may be missing, and supplemental materials like CDs or codes may not be included. May be ex-library with library markings. Ships promptly!
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Anbieter: Revaluation Books, Exeter, Vereinigtes Königreich
EUR 16,39
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In den WarenkorbPaperback. Zustand: Brand New. 194 pages. 9.00x6.00x0.44 inches. In Stock.
Anbieter: Books From California, Simi Valley, CA, USA
hardcover. Zustand: Fine.
Anbieter: Revaluation Books, Exeter, Vereinigtes Königreich
EUR 177,44
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In den WarenkorbHardcover. Zustand: Brand New. 1st edition. 246 pages. 11.00x8.50x0.75 inches. In Stock.
Anbieter: Majestic Books, Hounslow, Vereinigtes Königreich
EUR 241,29
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In den WarenkorbZustand: New.
Sprache: Englisch
Verlag: Foster Academics Sep 2023, 2023
ISBN 10: 1646465598 ISBN 13: 9781646465590
Anbieter: AHA-BUCH GmbH, Einbeck, Deutschland
Buch. Zustand: Neu. Neuware - Mitochondria are double-membrane-bound organelles found in eukaryotic cells. They build cable-like structures and deliver energy to cells with the help of oxidative phosphorylation (OXPHOS) process. Aging causes a wide range of interrelated conditions and is also a leading cause of various human diseases. The age-associated changes in mitochondria are linked with deterioration in mitochondrial function. The accumulation of oxidative damage and mutations caused by reactive oxygen species (ROS), mitochondrial functionality, and DNA volume and integrity decline with age. Mitochondrial dysfunction includes an increase in oxidative damage and a reduction in oxidative capacity, and plays a significant role in biological aging. The accumulation of dysfunctional mitochondria occurs in all the tissues with aging, including brain, liver and skeletal muscle. These dysfunctional mitochondria are marked and removed through an autophagic process named mitophagy. Mitochondrial dysfunction occurs in many neurodegenerative diseases such as Huntington's disease (HD), amyotrophic lateral sclerosis (ALS), Parkinson's disease (PD), Friedreich's ataxia (FRDA) and Alzheimer's disease (AD). This book explores all the important aspects of mitochondrial dysfunction and its impact on aging and diseases. Experts and students actively engaged in researches on mitochondrial dysfunction will find it full of crucial and unexplored concepts.