Ion channels structure function (16 Ergebnisse)

Hardcover. Zustand: Fair. Unbekannte Unterschrift / Widmung; Leichte Gebrauchsspuren. This compilation of articles features talks from the Centro de Estudios Cientificos (CECS) in Valdivia, celebrating the 60th birthdays of Ramon Latorre and Enrico Stefani. Ramon Latorre, a prominent figure in channel Biophysics, initially trained as a Biochemist but transitioned to biophysics under the mentorship of Guayo (Eduardo) Rojas during his Ph.D. at the Laboratorio de Fisiologia Celular in Montemar. His influential work at the N.I.H. with Gerald Ehrenstein and Harold Lecar marked a significant milestone in single ion channel Biophysics. This foundational research, conducted in planar bilayers, laid the groundwork for understanding voltage-dependent conductances through single channel studies, predating the later patch clamping techniques. Latorre was among the first to identify the significance of calcium-activated potassium channels and to investigate their properties in detail. He advanced the understanding of voltage and calcium modulation of open probability and conducted thorough studies on gating and its modulation by other ions. Additionally, he explored permeation and selectivity, producing seminal studies on water molecules within channels and barium occupancy. His findings have gained renewed attention with the recent description of the KcSa structure.…

Zustand: Good. Volume 46. This is an ex-library book and may have the usual library/used-book markings inside.This book has hardback covers. In good all round condition. No dust jacket. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,950grams, ISBN:0121533468. …

Hardcover. Zustand: Like New. First Edition. Publisher's hardback in nearly new condition: firm and square, strong joints, sharp corners, no bumps. Contents crisp, tight and clean; no pen-marks. Not from a library so no such stamps or labels. Looks and appears unread. Thus a tidy book in very presentable condition.…

Zustand: Fair. This is an ex-library book and may have the usual library/used-book markings inside.This book has hardback covers. In fair condition, suitable as a study copy. No dust jacket. Library sticker on front cover. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,1800grams, ISBN:9780199296750.…

HRD. Zustand: New. New Book. Shipped from UK. Established seller since 2000.

Zustand: New. pp. 476.

Paperback. Zustand: Brand New. reprint edition. 182 pages. 9.76x6.50x0.45 inches. In Stock.

Buch. Zustand: Neu. Neuware - This book discusses voltage-gated ion channels and their importance in drug discovery and development. The book includes reviews of the channel genome, the physiological bases of targeting ion channels in disease, the unique technologies developed for ion channel drug discovery, and the increasingly important role of ion channel screening in cardiac risk assessment. It provides an important reference for research scientists and drug discovery companies.…

Zustand: New. In English.

Hardcover. Zustand: gut. 2005. Series of the Centro de Estudios Científicos: Pumps, Transporters, and Ion Channels: Studies on Their Structure, Function, and Cell Biology In englischer Sprache. pages.

Hardcover. Zustand: Brand New. 1st edition. 475 pages. 9.29x6.06x1.10 inches. In Stock.

Zustand: New. VALENTIN K. GRIBKOFF, PHD, is the Chief Scientific Officer and Senior Vice President of Discovery Research at Knopp Neurosciences. He is also an Adjunct Associate Professor in the Department of Pharmacology at Yale University School of Medicine. Dr. Gribkof.

Zustand: New. This book discusses voltage-gated ion channels and their importance in drug discovery and development. Editor(s): Gribkoff, Valentin K.; Kaczmarek, Leonard K. Num Pages: 476 pages, Illustrations. BIC Classification: UN. Category: (P) Professional & Vocational. Dimension: 241 x 161 x 29. Weight in Grams: 806. . 2009. 1st Edition. Hardcover. . . . . Books ship from the US and Ireland.…

Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Unraveling the intricate mechanisms underlying ion channel structure and function requires a multifaceted approach. In this context, the synergistic integration of experimental and computational approaches is exceptionally powerful. However, it is only in the past decade that computational tools have garnered sufficient power to play a prominent role alongside experimental techniques. This volume highlights cutting-edge approaches for studying ion channel structure and function, providing methodological advances with broad applications and offering targeted insights into various channels, organized into two sections. The first section presents fundamental computational and experimental approaches central to ion channel research, including theoretical frameworks for delineating the forces that govern ion selectivity, molecular dynamics simulations for elucidating ion channel gating, advanced structural and fluorescence-based techniques, and mutagenesis-centered integrative methods. The second section explores the structure and function of a wide array of channel types, including the voltage-gated hERG potassium channel, two-pore domain potassium channels, the ryanodine receptorintracellular calcium channel, transient receptor potential vanilloid (TRPV) channels, pentameric ligand-gated ion channels, and aquaporin ion channels.Together, these chapters demonstrate how contemporary experimental and computational methods advance our understanding of ion channel structure and function. Showcasing these advances, this book is an invaluable resource for researchers and professionals in the ion channel field and the pharmaceutical industry.…

Buch. Zustand: Neu. Structure, Function, and Modulation of Neuronal Voltage-Gated Ion Channels | Valentin K Gribkoff (u. a.) | Buch | Preface.[.] 1 NEURONAL VOLTAGE-GATED ION CHANNEL FUNCTIONS.1 Neuronal L-Type Voltage-Gated Calcium Channels (Alexander Scriabine and David J. Triggle).2 Voltage-Gated N-Type and T-Type Calcium Channels and Excitability Disorders (Elizabeth | Englisch | 2009 | Wiley | EAN 9780471930136 | Verantwortliche Person für die EU: Libri GmbH, Europaallee 1, 36244 Bad Hersfeld, gpsr[at]libri[dot]de | Anbieter: preigu.…

Hardcover. Zustand: Brand New. 450 pages. 10.00x7.00x10.00 inches. In Stock.