Intrinsically disordered proteins disease (11 Ergebnisse)

hardcover. Zustand: Sehr gut. 248 Seiten; 9781646475407.2 Gewicht in Gramm: 1.

Gebundene Ausgabe. Zustand: Sehr gut. Gebraucht - Sehr gut - ungelesen,als Mängelexemplar gekennzeichnet, mit leichten Mängeln an Schnitt oder Umschlag durch Lager- oder Transportschaden -'Dancing protein clouds: Intrinsically disordered proteins in the norm and pathology' represents a set of selected studies on a variety of research topics related to intrinsically disordered proteins. Topics in this update include structural and functional characterization of several important intrinsically disordered proteins, such as 14-3-3 proteins and their partners, as well as proteins from muscle sarcomere; representation of intrinsic disorder-related concept of protein structure-function continuum; discussion of the role of intrinsic disorder in phenotypic switching; consideration of the role of intrinsically disordered proteins in the pathogenesis of neurodegenerative diseases and cancer; discussion of the roles of intrinsic disorder in functional amyloids; demonstration of the usefulness of the analysis of translational diffusion of unfolded and intrinsically disordered proteins; consideration of various computational tools for evaluation of functions of intrinsically disordered regions; and discussion of the role of shear stress in the amyloid formation of intrinsically disordered regions in the brain. 424 pp. Englisch.…

Hardcover. Zustand: Brand New. 256 pages. 10.75x8.25x0.75 inches. In Stock.

Zustand: New. In English.

Zustand: New. In English.

Buch. Zustand: Neu. Neuware - An intrinsically disordered protein (IDP) is a protein in which the fixed or ordered three-dimensional structure is absent, generally when its macromolecular interaction partners, such as other proteins or RNA are absent. The flexible structure of these proteins allows them to accomplish their biological functions. IDPs play an important role in DNA regulation and cell signaling owing to their ability to participate in weak multivalent interactions that are highly cooperative and dynamic. There are various IDPs that can adopt a fixed three-dimensional structure after they bind themselves to other macromolecules. IDPs are associated with numerous diseases such as cancer, cardiovascular disease, amyloidoses, neurodegenerative diseases and diabetes. This book includes some of the vital pieces of works being conducted across the world, on various topics related to the relationship between intrinsically disordered proteins and diseases. Its extensive content provides the readers with a thorough understanding of the subject.…

Zustand: gut. 2023. Intrinsically Disordered Proteins and Disease In englischer Sprache. pages.

Zustand: New. In English.

Zustand: New. Provides some recent studies on the intrinsically disordered proteins and their functions, as well as on the involvement of intrinsically disordered proteins in pthogenesis of various diseases Contains numerous illustrative materials (colo.

Zustand: New. Offers an in-depth exploration of the relationship between osmolytes and intrinsically disordered proteins (IDPs), spanning from basic functional regulation to roles in the pathogenesis of various diseaseFeatures chapters written by leading.

Buch. Zustand: Neu. Neuware - Osmolytes and Intrinsically Disordered Proteins: From Functional Regulation to Disease Pathogenesis, Volume 112 delves into the fascinating interplay between osmolytes and intrinsically disordered proteins (IDPs), exploring their pivotal roles in cellular function and disease mechanisms. This volume brings together experts to present cutting-edge research on how osmolytes regulate functional behavior of IDPs and ensure cellular stability and adaptability under stress conditions. Specific chapters cover Functional diversity of IDPs and their structural heterogeneity: Protein structure-function continuum, Osmolytes as structure-function regulators of intrinsically disordered casein, Synergism of the effects of osmolytes and crowders on structure and function of IDPs/IDRs: The natural habitat, and more.Additional chapters delve into Osmolyte-IDP Interactions during Desiccation, Modulation of aggregation/fibrillation propensity of IDPs by osmolytes, Osmolytes in modulating the structural and functional integrity of -synuclein: a study based on Parkinson's disease, Regulation of the structural dynamics, aggregation, and pathogenicity of polyQ-expanded Huntingtin by osmolytes, Aggregation and inhibitory strategies of amyloid fibrillation, and much more.…