Hit lead profiling identification (1 Ergebnisse)
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Hardcover. Zustand: Very Good. Hit and Lead Profiling: Identification and Optimization of Drug-like Molecules by Bernard Faller & Laszlo Urban eds.Includes inscription to 'Humphrey' by Laszlo UrbanMethods and Principles in Medicinal Chemistry, Vol. 43The only reference on current methods to generate pharmacokinetic and safety pr…ofiles of drug candidates, as well as how they must be balanced against one other for the best selection of candidates for further development. Following a brief introduction to the necessities of filtering and risk assessment of potential new drug molecules before actual drug development, the two equally important aspects of pharmacological (ADME) and safety (toxicity) profiling are covered in sep.
