Epigenetics brain behavior (17 Ergebnisse)
Sprache: Englisch
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Sprache: Englisch
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Taschenbuch. Zustand: Neu. Epigenetics, Brain and Behavior | Paolo Sassone Corsi (u. a.) | Taschenbuch | Research and Perspectives in Neurosciences | x | Englisch | 2014 | Springer | EAN 9783642441080 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[…dot]com | Anbieter: preigu.
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Verlag: Springer, 2014
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Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Recent years have seen spectacular advances in the filed of epigenetics. These have attracted the interest of researchers in many fields and evidence connecting epigentic regulation to brain functions has been accumulationg. Neurons daily convert a v…ariety of external stimuli into rapid or long-lasting changes in gene expression. A variety of studies have centered on the molcular mechanisms implicated in epigentic control and how these may operte in concert. It will be critical to unravel how specifity is achieved. The focus of this volume is on critical epigenetic regulation and chromatin remodeling events that occur in the nervous system and on the presumed mechanisms that operate within neurons to translate them into long-lasting neuronal responses.
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Sprache: Englisch
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Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - What lies at the heart of neuronal plasticity Accumulating evidence points to epigenetics. This word originally indicated potentially heritable modifications in gene expression that do not involve changes in DNA sequence. Today this definition is much less…strict, and epigenetic control is thought to include DNA methylation, histone modifications, histone variants, microRNA metabolic pathways and non-histone proteins modifications. Thus, while neuronal plasticity is rightly thought to be intimately associated to genomic control, it is critical to appreciate that there is much more to the genome than DNA sequence.Recent years have seen spectacular advances in the field of epigenetics. These have attracted the interest of researchers in many fields and evidence connecting epigenetic regulation to brain functions has been accumulating. Neurons daily convert a variety of external stimuli into rapid or long-lasting changes in gene expression. A variety of studies have centered on the molecular mechanisms implicated in epigenetic control and how these may operate in concert. It will be critical to unravel how specificity is achieved. Importantly, specific modifications seem to mediate both developmental processes and adult brain functions, such as synaptic plasticity and memory. Many aspects of the research in neurosciences and endocrinology during the upcoming decade will be dominated by the deciphering of epigenetic control. This book constitutes a compendium of the most updated views in the field.
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Zustand: Sehr gut. Zustand: Sehr gut | Sprache: Englisch | Produktart: Bücher | Recent years have seen spectacular advances in the filed of epigenetics. These have attracted the interest of researchers in many fields and evidence connecting epigentic regulation to brain functions has been accumulationg. Neurons daily convert a v…ariety of external stimuli into rapid or long-lasting changes in gene expression. A variety of studies have centered on the molcular mechanisms implicated in epigentic control and how these may operte in concert. It will be critical to unravel how specifity is achieved. The focus of this volume is on critical epigenetic regulation and chromatin remodeling events that occur in the nervous system and on the presumed mechanisms that operate within neurons to translate them into long-lasting neuronal responses.
Sprache: Englisch
Verlag: Springer Verlag, 2014
Serie: Buch 5 von 14 - Research and Perspectives in Neurosciences
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Paperback. Zustand: Brand New. 2012 edition. 176 pages. 9.25x6.10x0.40 inches. In Stock.
Sprache: Englisch
Verlag: Springer Verlag, 2012
Serie: Buch 5 von 14 - Research and Perspectives in Neurosciences
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Taschenbuch. Zustand: Neu. Brain, Behavior and Epigenetics | Arturas Petronis (u. a.) | Taschenbuch | Epigenetics and Human Health | xvi | Englisch | 2013 | Springer | EAN 9783642268328 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbie…ter: preigu.
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Zustand: Sehr gut. Zustand: Sehr gut | Seiten: 336 | Sprache: Englisch | Produktart: Bücher | Biomedical research in the first decade of the 21st century has been marked by a rapidly growing interest in epigenetics. The reasons for this are numerous, but primarily it stems from the mounting realization that research programs foc…used solely on DNA sequence variation, despite their breadth and depth, are unlikely to address all fundamental aspects of human biology. Some questions are evident even to non-biologists. How does a single zygote develop into a complex multicellular organism composed of dozens of different tissues and hundreds of cell types, all genetically identical but performing very different functions? Why do monozygotic twins, despite their stunning external similarities, often exhibit significant differences in personality and predisposition to disease? If environmental factors are solely the cause of such variation, why are similar differences also observed between genetically identical animals housed in a uniform environment? Over the last couple of decades, epigenetics has undergone a significant metamorphosis from an abstract developmental theory to a very dynamic and rapidly developing branch of molecular biology. This volume represents a compilation of our current understanding about the key aspects of epigenetic processes in the brain and their role in behavior. The chapters in this book bring together some of the leading researchers in the field of behavioral epigenetics. They explore many of the epigenetic processes which operate or may be operating to mediate neurobiological functions in the brain and describe how perturbations to these systems may play a key role in mediating behavior and the origin of brain diseases.
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Sprache: Englisch
Verlag: Springer Berlin Heidelberg, Springer Berlin Heidelberg, 2011
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Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Epigenetic processes can explain some of the epidemiological associations between environmental exposure and disease, particularly when the exposure occurs at a critical delopmental stage.Epigenetics, a cellular mechanism once considered to be stable after…development, has now been found to be a dynamic process that occurs in fully differentiated, post-mitotic cells of central nervous system in response to environmental signals. Epigenetic mechanisms regulate the structure of the chromatin through post-translational modifications of histone proteins and covalent DNA modifications. Though the mechanisms through which these effects are achieved likely involve diverse cellular and molecular pathways, there is emerging evidence supporting the hypothesis that epigenetic changes, such as DNA methylation and histone modifications, may mediate the effects of early-life variations in the social interactions between mothers and infants.
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Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Biomedical research in the first decade of the 21st century has been marked by a rapidly growing interest in epigenetics. The reasons for this are numerous, but primarily it stems from the mounting realization that research programs focused solely on… DNA sequence variation, despite their breadth and depth, are unlikely to address all fundamental aspects of human biology. Some questions are evident even to non-biologists. How does a single zygote develop into a complex multicellular organism composed of dozens of different tissues and hundreds of cell types, all genetically identical but performing very different functions Why do monozygotic twins, despite their stunning external similarities, often exhibit significant differences in personality and predisposition to disease If environmental factors are solely the cause of such variation, why are similar differences also observed between genetically identical animals housed in a uniform environment Over the last couple of decades, epigenetics has undergone a significant metamorphosis from an abstract developmental theory to a very dynamic and rapidly developing branch of molecular biology. This volume represents a compilation of our current understanding about the key aspects of epigenetic processes in the brain and their role in behavior. The chapters in this book bring together some of the leading researchers in the field of behavioral epigenetics. They explore many of the epigenetic processes which operate or may be operating to mediate neurobiological functions in the brain and describe how perturbations to these systems may play a key role in mediating behavior and the origin of brain diseases.
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