Development vertebrate retina (7 Ergebnisse)
Sprache: Englisch
Verlag: Springer, 1982
Serie: Buch 43 von 173 - Advances in Anatomy, Embryology and Cell Biology
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Sprache: Englisch
Verlag: Springer Berlin Heidelberg, 1982
Serie: Buch 43 von 173 - Advances in Anatomy, Embryology and Cell Biology
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Zustand: Gut. Zustand: Gut | Seiten: 282 | Sprache: Englisch | Produktart: Bücher | Keine Beschreibung verfügbar.
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Sprache: Englisch
Verlag: Springer, Springer, 1982
Serie: Buch 43 von 173 - Advances in Anatomy, Embryology and Cell Biology
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Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The mature vertebrate retina is a highly complicated array of several kinds of cells, capable of receiving light impulses, transforming them into neuronal membrane currents, and transmitting these in a meaningful way to central processing. Before it…starts to develop, it is a small sheet of unconspicuous cells, which do not differ from other cells of the central nervous system. The chain of events which lead to the trans formation from this stage into that of highly specialized cells ready to fulfll a specific task, is usually called 'differentiation. ' Originally, this word indicated firstly the proc ess of divergence from other cells which were previously alike, and secondly, the change from an earlier stage of the same cello lt has become widespread practice to imply by the word 'differentiation' also the acquisition of specific properties and capacities which are characteristic of a mature, Le. , specifically active, cello Every cell is active at any stage of development, but certain activities are shared by most cells (e. g. , the activities of preparing and accomplishing proliferation, that of initiating development, that of maintaining a certain level of metabolism), while there are others which are shared by only a small number of - originally relate- cells. In most cases these latter activities are acquired by the fmal steps of cellular development, the terminal 'differentiation. ' In the context of the present paper, the word 'function' will refer to this latter type of specific activity.
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Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The vertebrate retina has a form that is closely and clearly linked to its func tion. Though its fundamental cellular architecture is conserved across verte brates, the retinas of individual species show variations that are also of clear and direct f…unctional utility. Its accessibility, readily identifiable neuronal types, and specialized neuronal connectivity and morphology have made it a model system for researchers interested in the general questions of the genet ic, molecular, and developmental control of cell type and shape. Thus, the questions asked of the retina span virtually every domain of neuroscientific inquiry-molecular, genetic, developmental, behavioral, and evolutionary. Nowhere have the interactions of these levels of analysis been more apparent and borne more fruit than in the last several years of study of the develop ment of the vertebrate retina. Fields of investigation have a natural evolution, rdoving through periods of initial excitement, of framing of questions and controversy, to periods of synthesis and restatement of questions. The study of the development of the vertebrate retina appeared to us to have reached such a point of synthesis. Descriptive questions of how neurons are generated and deployed, and ques tions of mechanism about the factors that control the retinal neuron's type and distribution and the conformation of its processes have been posed, and in good part answered. Moreover, the integration of cellular accounts of development with genetic, molecular, and whole-eye and behavioral accounts has begun.
