Complement health disease (22 Ergebnisse)
Sprache: Englisch
Verlag: New York Academy, 1961
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In den WarenkorbBroschiert. Zustand: Gut. 335 Seiten; Das hier angebotene Buch stammt aus einer teilaufgelösten Bibliothek und kann die entsprechenden Kennzeichnungen aufweisen (Rückenschild, Instituts-Stempel.); der Buchzustand ist ansonsten ordentlich und dem Alter entsprechend gut. Neben dem oben aufgeführten Aufsatz befinden sich auch weite…re Beiträge auch anderer Autoren in dem Werk. In ENGLISCHER Sprache. Sprache: Englisch Gewicht in Gramm: 560.
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Zustand: Good. This is an ex-library book and may have the usual library/used-book markings inside.This book has hardback covers. In good all round condition. No dust jacket. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,750grams, ISBN:0852009542.
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Cloth/Laminated Boards. Zustand: Very Good. Zustand des Schutzumschlags: No d/j as Published. Second Edition. Type: Book The complement system plays a major role in the host's defence against infections and in immune complex diseases. Although it is known to consist of a number of serum and membrane proteins that interact throug…h a cascade, there is still a poor understanding of the exact nature of the components and their complex interaction. Many of the biological consequences of complement activation also await elucidation. This fully revised edition of "Complement in Health and Disease" provides an up-to-date account of how the system works and its effects on the host. Key topics covered include the history, phylogeny and evolution of the system; genetics and biochemistry; deficiency states and infection; immune complex diseases; complement and angioedema; anaphylatoxins; and diseases of the nervous system. The book is valuable both for those wanting an introduction to this complex area of immunology as well as those requiring a more detailed update on developments in specific topics.383pp.
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Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The complement system plays a major role in the host's defence against infections and in immune complex diseases. Although it is known to consist of a number of serum and membrane proteins that interact through a cascade, there is still a poor understanding… of the exact nature of the components and their complex interaction. Many of the biological consequences of complement activation also await elucidation. This fully revised edition of Complement in Health and Disease provides an up-to-date account of how the system works and its effects on the host. Key topics covered include the history, phylogeny and evolution of the system; genetics and biochemistry; deficiency states and infection; immune complex diseases; complement and angioedema; anaphylatoxins; and diseases of the nervous system. The book is valuable both for those wanting an introduction to this complex area of immunology as well as those requiring a more detailed update on developments in specific topics.
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Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Since the first edition of Complement in Health and Disease was published in 1986, significant advances have been made. The cDNAs for all of the components and some of the receptors have been cloned and sequenced. The chromosomal localization and the… structural organization of a number of these genes have now been determined. These advances are now facilitating research into the structure of the complement proteins, the nature of the complement deficiency syndromes, the regulation of complement gene expression and the role of complement in different diseases. This edition contains contributions from both basic and clinical scientists in a format which we hope will appeal to both immunologists and physicians who wish to know more about this fascinating and important host defence system. The introductory chapter by John Weiler presents a historical background to research on the complement system and describes the biochemical events occurring during activation of the system. In Chapter 2 Alastair Dodds and Tony Day discuss the phylogeny and evolution of the complement system. The techniques of protein chemistry and molecular biology have provided powerful insights into the modular structure of complement proteins and the evolution of the complement system. The structure and organisation of the complement genes is described in Chapter 3 by Ken Reid and Duncan Campbell. This chapter describes the modular structure of the complement proteins and some of the mutations which are responsible for deficiencies of individual components.
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Gebunden. Zustand: New. The complement system plays a major role in the host s defence against infections and in immune complex diseases. Although it is known to consist of a number of serum and membrane proteins that interact through a cascade, there is still a poor understanding.
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Buch. Zustand: Neu. Neuware - The part of the immune system, which improves the abilities of antibodies and phagocytic cells that eliminate microbes and destroyed cells from an organism, is known as the complement system. It also promotes inflammation and damages the pathogen's cell membrane. It is a continuous process and hence… belongs to the innate immune system. It is non-adaptive and has a lifelong presence. The complement system can be used by antibodies, which are produced by the adaptive immune system. Various small proteins are included in the complement system which synthesize through the liver and circulate as inactive precursors in the blood. There are three biochemical pathways which contribute in the activation of complement system, namely, the alternative complement pathway, the classical complement pathway and the lectin pathway. Such selected concepts that redefine the study of the human complement system have been presented in this book. It aims to serve as a resource guide for students and experts alike and contribute to the growth of research in this area of study. Those in search of information to further their knowledge will be greatly assisted by this book.
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Taschenbuch. Zustand: Neu. The Complement System | Novel Roles in Health and Disease | Janos Szebeni | Taschenbuch | xxi | Englisch | 2013 | Springer | EAN 9781475779288 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.
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Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - As a phylogenetically old system complement is now regarded as a part of innate immunity. But it is much more than that. It bridges innate and adapted immunity, participates not only in host defense but also in many essential physiological processes,… old and new diseases and adverse conditions. Indeed, complement became a term that almost defies categorization. What was for a long time a subject for a limited number of specialists has now moved into the mainstream of experimental and clinical immunology. In 1973 I visited the Basel Institute of Immunology and met its director, the eminent scientist and Nobel laureate Nils Jerne. When I entered his office he greeted me with the following words: 'Complement, does that really exist ' I was never certain whether he wanted only to tease me or whether he sincerely believed that the complement system was an unimportant biological curiosity, a misstep of evolution. But, of course, missteps do not survive the evolutionary process. Little did I foresee the dramatic developments of recent years when Hans J. Müller-Eberhard and I started to unravel the specifics of the action of the cobra venom factor on the complement system in 1968 and defined a new pathway to its activation. An elucidation of the role of the system in diseases and its control for therapeutic reasons is now getting closer to actual realization in the clinic although many problems, in particular those of highly specificinhibition free of side effects, have still to be resolved.
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Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - As a phylogenetically old system complement is now regarded as a part of innate immunity. But it is much more than that. It bridges innate and adapted immunity, participates not only in host defense but also in many essential physiological processes, old an…d new diseases and adverse conditions. Indeed, complement became a term that almost defies categorization. What was for a long time a subject for a limited number of specialists has now moved into the mainstream of experimental and clinical immunology. In 1973 I visited the Basel Institute of Immunology and met its director, the eminent scientist and Nobel laureate Nils Jerne. When I entered his office he greeted me with the following words: 'Complement, does that really exist ' I was never certain whether he wanted only to tease me or whether he sincerely believed that the complement system was an unimportant biological curiosity, a misstep of evolution. But, of course, missteps do not survive the evolutionary process. Little did I foresee the dramatic developments of recent years when Hans J. Müller-Eberhard and I started to unravel the specifics of the action of the cobra venom factor on the complement system in 1968 and defined a new pathway to its activation. An elucidation of the role of the system in diseases and its control for therapeutic reasons is now getting closer to actual realization in the clinic although many problems, in particular those of highly specificinhibition free of side effects, have still to be resolved.
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Buch. Zustand: Neu. Neuware - This authoritative, single-source reference provides comprehensive examinations of the complement system-offering recent findings in basic science on the structure, biology, physiology, and pathophysiology of complement proteins and the latest therapeutic approaches towards the control of complement…-mediated diseases. Written by over 40 international experts from North America, Europe, and Asia, The Human Complement System in Health and Disease- describes the molecular architecture of the complement system - details the structure of complement genes - discusses gene organization as well as the topology and chemistry of ligand-binding sites and catalytic centers of complement proteins - analyzes complement organization and activation, including phylogeny and the newly discovered lectin pathway - elucidates the regulation of complement gene expression and the structure and function of bioactive peptides - explicates opsonic and immunoregulatory properties of complement fragments, endothelial responses, and interactions with viruses and bacteria - and more.
Verlag: MTP Press/ Kluwer Academic, 1987., 1987
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In den WarenkorbHardcover. Ex-library, o/wise good (no markings to text). No dj. 326pp. ISBN 0852009542. 11436.
