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In den WarenkorbZustand: New. pp. 540 Illus.
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In den WarenkorbTaschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This book stems from a conference held at Magdeburg-Herrenkrug, Germany, in November 1996 on 'Cellular Peptidases in Immune Functions and Diseases. ' This sympo sium was designed to bring together scientists from diverse areas of expertise to discuss issues of newly identified relevance of proteolytic processes and their role as molecular regulators in the immune system and in diseases. The meeting was organized by the Son derforschungsbereich 387 of the Deutsche Forschungsgemeinschaft 'ZelluHire Proteasen, Bedeutung fiir Immunmechanismen und entziindliche Erkrankungen,' which links re search groups from the Otto von Guericke University Magdeburg and the Martin Luther University Halle. It has become clear during the last decade that proteolysis, the processing and degrada tion of peptides and proteins, has to be considered as a special level of epigenetic control of practically all processes of life and-an understanding dating from the last three years or so--also of cell death or apoptosis. There is also increasing evidence that proteolysis does play a crucial role in all areas of immune functions as well as in inflammatory and neoplastic diseases. Cellular proteases have central functions in natural (nonspecific) as well as acquired in the cognitive phase (antigen processing and presen (specific) immunity. They are involved tation), in the activation phase (e. g. , generation and processing of cytokines, function of CD26, CD 13, processing of transcription factors) as well as in the effector phase of the im mune response (e. g. , complement system, granzymes, elastase, proteinase 3.
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In den WarenkorbGebunden. Zustand: New. Proceedings of an international conference held in Magdeburg, Germany, November 3-5, 1996 Membrane Peptidases in Immune Functions and Inflammation: Membrane Metalloendopeptidases in Immune Function and Disease J.S. Bond, W. Jiang. Structural Studies.
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In den WarenkorbTaschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Of the many special roles played by proteolytic enzymes in immune reactions, this book addresses different aspects of membrane peptidases, signal transduction via ligation of membrane peptidases (especially of dipeptidyl peptidase IV/CD26 and aminopeptidase N/CD13), and regulation of membrane peptidases in vivo and in vitro. A number of newly discovered peptidases (including cathepsin F, W and X, carboxypeptidase X, attractin) are described, with special emphasis given to the role of peptidases in immune and defense reactions and in the pathogenesis of inflammatory and other diseases, including rheumatoid arthritis, pancreatitis, multiple sclerosis, Alzheimer's disease and tumours of various origins. The focus on the involvement of a selection of proteolytic enzymes in immune reactions and diseases is a unique feature of this multifaceted work , which combines biochemical, immunological and clinical research reports with literary reviews of the field.
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In den WarenkorbBuch. Zustand: Neu. Neuware - This book stems from a conference held at Magdeburg-Herrenkrug, Germany, in November 1996 on 'Cellular Peptidases in Immune Functions and Diseases. ' This sympo sium was designed to bring together scientists from diverse areas of expertise to discuss issues of newly identified relevance of proteolytic processes and their role as molecular regulators in the immune system and in diseases. The meeting was organized by the Son derforschungsbereich 387 of the Deutsche Forschungsgemeinschaft 'ZelluHire Proteasen, Bedeutung fiir Immunmechanismen und entziindliche Erkrankungen,' which links re search groups from the Otto von Guericke University Magdeburg and the Martin Luther University Halle. It has become clear during the last decade that proteolysis, the processing and degrada tion of peptides and proteins, has to be considered as a special level of epigenetic control of practically all processes of life and-an understanding dating from the last three years or so--also of cell death or apoptosis. There is also increasing evidence that proteolysis does play a crucial role in all areas of immune functions as well as in inflammatory and neoplastic diseases. Cellular proteases have central functions in natural (nonspecific) as well as acquired in the cognitive phase (antigen processing and presen (specific) immunity. They are involved tation), in the activation phase (e. g. , generation and processing of cytokines, function of CD26, CD 13, processing of transcription factors) as well as in the effector phase of the im mune response (e. g. , complement system, granzymes, elastase, proteinase 3.
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In den WarenkorbBuch. Zustand: Neu. Neuware - Of the many special roles played by proteolytic enzymes in immune reactions, this book addresses different aspects of membrane peptidases, signal transduction via ligation of membrane peptidases (especially of dipeptidyl peptidase IV/CD26 and aminopeptidase N/CD13), and regulation of membrane peptidases in vivo and in vitro. A number of newly discovered peptidases (including cathepsin F, W and X, carboxypeptidase X, attractin) are described, with special emphasis given to the role of peptidases in immune and defense reactions and in the pathogenesis of inflammatory and other diseases, including rheumatoid arthritis, pancreatitis, multiple sclerosis, Alzheimer's disease and tumours of various origins. The focus on the involvement of a selection of proteolytic enzymes in immune reactions and diseases is a unique feature of this multifaceted work , which combines biochemical, immunological and clinical research reports with literary reviews of the field.