antibody engineering protocols (29 Ergebnisse)

Hardcover. Zustand: As New. No Jacket. Pages are clean and are not marred by notes or folds of any kind. ~ ThriftBooks: Read More, Spend Less.

Hardcover. Zustand: Very Good. No Jacket. Former library book; May have limited writing in cover pages. Pages are unmarked. ~ ThriftBooks: Read More, Spend Less.

Zustand: New. Brand New. Soft Cover International Edition. Different ISBN and Cover Image. Priced lower than the standard editions which is usually intended to make them more affordable for students abroad. The core content of the book is generally the same as the standard edition. The country selling restrictions may be printed on the book but is no problem for the self-use. This Item maybe shipped from US or any other country as we have multiple locations worldwide.

Zustand: New. In.

Spiralbuch. Zustand: Gut. 450 Seiten Der Erhaltungszustand des hier angebotenen Werks ist trotz seiner Bibliotheksnutzung sehr sauber. Es befindet sich neben dem Rückenschild lediglich ein Bibliotheksstempel im Buch; ordnungsgemäß entwidmet. In ENGLISCHER Sprache. Sprache: Englisch Gewicht in Gramm: 600.

Zustand: Sehr gut. Zustand: Sehr gut | Seiten: 576 | Sprache: Englisch | Produktart: Bücher | The exquisite binding specificity of antibodies has made them valuable tools from the laboratory to the clinic. Since the description of the murine hybridoma technology by Köhler and Milstein in 1975, a phenomenal number of mo- clonal antibodies have been generated against a diverse array of targets. Some of these have become indispensable reagents in biomedical research, while others were developed for novel therapeutic applications. The attractiveness of an- bodies in this regard is obvious¿high target specificity, adaptability to a wide range of disease states, and the potential ability to direct the host¿s immune s- tem for a therapeutic response. The initial excitement in finding Paul Ehrlich¿s ¿magic bullet,¿ however, was met with widespread disappointment when it was demonstrated that murine antibodies frequently elicit the human anti-murine an- body (HAMA) response, thus rendering them ineffective and potentially unsafe in humans. Despite this setback, advances in recombinant DNA techniques over the last 15¿20 years have empowered the engineering of recombinant antibodies with desired characteristics, including properties to avoid HAMA. The ability to p- duce bulk quantities of recombinant proteins from bacterial fermentation also fueled the design of numerous creative antibody constructs. To date, the United States Food and Drug Administration has approved more than 10 recombinant antibodies for human use, and hundreds more are in the development pipeline. The recent explosion in genomic and proteomic information appears ready to deliver many more disease targets amenable to antibody-based therapy.

Zustand: New. This collection of developed methods for producing new antibody reagents by immunization and recombinant DNA techniques contains ready-to-use protocols that illuminate current areas of research on antibody structure. It aims to minimize extensive literature and methodology searches. Series: Methods in Molecular Biology. Num Pages: 450 pages, biography. BIC Classification: MJCM; PSD; TCB. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 23. Weight in Grams: 661. . 1995. Paperback. . . . . Books ship from the US and Ireland.

Zustand: Fair. This is an ex-library book and may have the usual library/used-book markings inside.This book has hardback covers. In fair condition, suitable as a study copy. No dust jacket. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,1300grams, ISBN:9781493986477.

Zustand: Good. Your purchase helps support Sri Lankan Children's Charity 'The Rainbow Centre'. Ex-library, so some stamps and wear, but in good overall condition. Our donations to The Rainbow Centre have helped provide an education and a safe haven to hundreds of children who live in appalling conditions.

Kartoniert / Broschiert. Zustand: New. SEQHUNT: A Program to Screen Aligned Nucleotide and Amino Acid Sequences. Molecular Modeling of Antibody-Combining Sites. Structure and Properties of Human Immunoglobulin Light-Chain Dimers. Crystallographic and Chromatographic Methods for Study of Antibody.

Zustand: Very Good. 2. Very Good; Hardcover; 2nd Edition; Light wear to the covers; Unblemished textblock edges; The endpapers and all text pages are clean and unmarked; The binding is excellent with a straight spine; This book will be shipped in a sturdy cardboard box with foam padding; Medium Format (8.5" - 9.75" tall); 3.3 lbs; Dark green covers with title in white lettering; 2010, Springer-Verlag Publishing; 788 pages; "Antibody Engineering Volume 1 (Springer Protocols)," by Roland E. Kontermann & Stefan Dübel.

Zustand: New. In.

Zustand: Very Good. 2. Very Good++; Hardcover; Close to new condition; Covers are still glossy with "straight" edge-corners; Unblemished textblock edges; The endpapers and all text pages are bright and unmarked; Binding is tight with a straight spine; This book will be stored and delivered in a sturdy cardboard box with foam padding; Medium Format (8.5" - 9.75" tall); Dark green covers with title in white lettering; 2nd Edition; 2010, Springer-Verlag Publishing; 788 pages; "Antibody Engineering Volume 1 (Springer Protocols)," by Roland E. Kontermann & Stefan Dübel.

Zustand: New. In.

Zustand: New. In.

Taschenbuch. Zustand: Neu. Antibody Engineering | Methods and Protocols | Damien Nevoltris (u. a.) | Taschenbuch | xvi | Englisch | 2019 | Humana | EAN 9781493993536 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.

Taschenbuch. Zustand: Neu. Neuware - Antibodies are the instraments of immune defense and attack. They can bind small atomic arrays as well as large epitopes with high affinity. Antibody Engineering Protocols presents advanced protocols in the field of antibody engineering, reviews of basic principles and methodology, and a historical perspective on the development of cur rently held beliefs about antibody structure-function relationships. The topics cover analysis of antibody sequences, three-dimensional structure, delineation of antibody characteristics in polyclonal mixtures, phage display of natural and synthetic antibodies, and antibody catalysis. Ligand recognition by antibodies occurs primarily at a subset of amino acid residues located in the complementarity determining regions (CDRs) found in the light (L) and heavy (H) chain subunits. Specific antibodies are developed by immunization with molecules identical to or related in structure to the target ligand. The immune repertoire from nonimmunized individuals also contains pre-existing specificities that can be selected by screening libraries composed of hybridoma cells or phage particles displaying F domains or indi vidual variable domains of the light (VJ and heavy (V^^) chains. Ran dom or site-directed mutagenesis in vitro can be used to refine the pre-existing specificities or produce new specificities de novo. Another level at which new specificities may be generated in vitro is V^ and V^ domain-swapping and CDR-swapping. The former procedure embodies a variation of natural mechanisms of generating antibody diversity. The latter procedure produces new intramolecular CDR combinations not found in nature.

Zustand: New. In.

Zustand: Hervorragend. Zustand: Hervorragend | Seiten: 560 | Sprache: Englisch | Produktart: Bücher | This detailed new edition provides complete and easy access to a variety of antibody engineering techniques. The volume explores topics such as the generation of native, synthetic, or immune antibody libraries, the selection of lead candidates via the different powerful and innovative display technologies, Fc engineering, as well as their production, characterization, and optimization of antibodies. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Antibody Engineering: Methods and Protocols, Third Edition presents the reader with an extensive toolbox to create the powerful molecules of tomorrow.

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This detailed new edition provides complete and easy access to a variety of antibody engineering techniques. The volume explores topics such as the generation of native, synthetic, or immune antibody libraries, the selection of lead candidates via the different powerful and innovative display technologies, Fc engineering, as well as their production, characterization, and optimization of antibodies. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and up-to-date, Antibody Engineering: Methods and Protocols, Third Edition presents the reader with an extensive toolbox to create the powerful molecules of tomorrow.

Taschenbuch. Zustand: Neu. Antibody Engineering | Methods and Protocols, Second Edition | Patrick Chames | Taschenbuch | xvi | Englisch | 2016 | Humana | EAN 9781493959440 | Verantwortliche Person für die EU: Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.

Zustand: New. In English.

Paperback. Zustand: Brand New. 3rd reprint edition. 559 pages. 9.25x6.10x1.26 inches. In Stock.

Paperback. Zustand: Brand New. 2nd reprint edition. 734 pages. 10.00x7.01x1.50 inches. In Stock.

Zustand: New. 2016. Paperback. . . . . . Books ship from the US and Ireland.

Hardcover. Zustand: Brand New. 2nd edition. 734 pages. 10.25x7.25x1.75 inches. In Stock.

Zustand: New. In.

Hardcover. Zustand: Brand New. 3rd edition. 543 pages. 10.50x7.25x7.50 inches. In Stock.

Zustand: New. 2018. Third Edition 2018. hardcover. . . . . . Books ship from the US and Ireland.