9798903628186 - fundamentals of computer aided drug design von girija sastry vedula; suresh chinthakindi; ramana hechhu (2 Ergebnisse)
- Hardcover
Anbieter: PBShop.store UK, Fairford, GLOS, Vereinigtes KönigreichPBShop.store UK
Verkäufer/-in kontaktierenVerkäufer/-in mit 5 SternenZustand: Neu
EUR 29,54
EUR 5,88 VersandVersand von Vereinigtes Königreich nach USAAnzahl: Mehr als 20 verfügbar
HRD. Zustand: New. New Book. Shipped from UK. Established seller since 2000.
- Weitere Bilder
- Hardcover
Anbieter: AHA-BUCH GmbH, Einbeck, DeutschlandAHA-BUCH GmbH
Verkäufer/-in kontaktierenVerkäufer/-in mit 5 SternenZustand: Neu
EUR 42,50
EUR 63,04 VersandVersand von Deutschland nach USAAnzahl: 2 verfügbar
Buch. Zustand: Neu. Neuware - The integration of computational methods into drug discovery has reshaped how molecular design, analysis, and optimization are performed in pharmaceutical research. This text presents a structured treatment of the principles governing the prediction of biological activity from molecular structure.Th…e content progresses from physicochemical foundations to quantitative modeling, explaining how electronic, steric, and hydrophobic factors influence drug-receptor interactions. Quantitative Structure-Activity Relationships are addressed through both two-dimensional and three-dimensional approaches, supported by statistical interpretation and validation.Molecular modeling techniques, including molecular mechanics, quantum chemical methods, energy minimization, and conformational analysis, are discussed with emphasis on structural accuracy and biological relevance. Molecular docking is examined through rigid and flexible approaches, along with scoring functions and validation protocols.Key Features- Coverage of physicochemical principles in drug design- 2D-QSAR and 3D-QSAR with validation approaches- Molecular modeling and conformational analysis- Molecular docking methods and scoring functions- ADMET prediction and toxicity assessment- Pharmacophore modeling and virtual screeningExclusively written for M.Pharm students as per PCI Syllabus.
