9789401067492 - clinical application of radiolabelled platelets (developments in nuclear medicine, band 17) (3 Ergebnisse)
Sprache: Englisch
Verlag: Springer, 2011
Serie: Developments in Nuclear Medicine, Buch 14 von 33. Buch 14 von 33 - Developments in Nuclear Medicine
- Softcover
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Clinical Application of Radiolabelled Platelets
Kessler, C. (Editor)/ Henningsen, H. (Editor)/ Petrovici, J. (Editor)/ Hardeman, M.R. (Editor)
Sprache: Englisch
Verlag: Kluwer Academic Publisher, 2013
Serie: Developments in Nuclear Medicine, Buch 14 von 33. Buch 14 von 33 - Developments in Nuclear Medicine
- Softcover
Anbieter: Revaluation Books, Exeter, Vereinigtes KönigreichRevaluation Books
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Paperback. Zustand: Brand New. 312 pages. 9.25x6.10x0.71 inches. In Stock.
Sprache: Englisch
Verlag: Springer Netherlands, 2011
Serie: Developments in Nuclear Medicine, Buch 14 von 33. Buch 14 von 33 - Developments in Nuclear Medicine
- Softcover
Anbieter: AHA-BUCH GmbH, Einbeck, DeutschlandAHA-BUCH GmbH
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Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - AIMS OF THE COLOGNE-SYMPOSIUM ON RADIOLABELLED PLATELETS In 1976, M. Thakur et al (1) were the first to publish a paper concerning the in vivo thrombus detection with 111- In-labelled platelets. Previous attempts at scintigraphic thrombus localisatio…n had been disappointing because of the unspecific binding of a number of the isotopes used, as well as the poor labelling efficiency or an insufficient low gamma-emitting property. Because of its physical characteristics (2.8 days half-life, 94% gamma emission) 111 Indium turned out to be the best isotope for platelet kinetic studies as well as for the measurement of platelet incorporation by Thrombi to be used up until now. The lipophile complexes of Ill-In (8-hydroxyquinoline, acetylacetone, tropolone) diffuse passively into the platelets without altering the function or the life span of the platelets. This advantage has let to an increase in the clinical applications of 1211-In labelled platelets. Today, radiolabelled platelets are used for thrombus detection in several different medical areas such as cardiology, nephrology. angiology or neurology. Even though many scientists and hospital doctors now routinely use radiolabelled platelet as a diagnostic tool, there is as yet not a standardized labelling method. In addition to this, there are neither standardized image procedures for the different clinical applications nor an agreement about specificity and sensitivity of the method. In 1983, a symposium on Radiolabelled Cellular Blood Elements was organized by M.Thakur, M.R.Hardeman and M.D.
