9783764366001 - Combination Therapy of AIDS (Milestones in Drug Therapy) (6 Ergebnisse)

Hardcover. Zustand: Wie neu. XI, 243 S.; Ill. Like new. Shrink wrapped. Sprache: Englisch Gewicht in Gramm: 855.

2004th ed. 15 x 23 cm. 254 pages. HC Versand aus Deutschland / We dispatch from Germany via Air Mail. Einband bestoßen, daher Mängelexemplar gestempelt, sonst sehr guter Zustand. Imperfect copy due to slightly bumped cover, apart from this in very good condition. Stamped. Sprache: Englisch.

Zustand: New. In.

Zustand: New. pp. 260 Illus.

Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - HIV infection has been a greater challenge to current medicine than any other viral disease ofmodem times. HIV leads to a persistent infection and the virus has an immense genetic flexibility under selective pressure. During its replica tive cycle in patients, HIV accumulates mutations at such a high rate that the selective pressure inflicted on the immune system, or generated by antiviral drugs rapidly triggers the appearance of escape mutants. Currently available drugs, when used singly, are not capable of suppressing virus replication in patients to such a level that the generation of mutations, from which a variant resistant to immune attack or antiviral drugs can be selected, is prevented. This is the main reason why combination therapy, usually of three drugs, has become the standard procedure for the treatment ofAIDS. It is obvious that virus eradication will not readily be achievable, so that drugs have to be taken for a prolonged time or even lifelong so as to keep the viral load as low as possible. Whether the currently used drug combinations will be able to control virus replication in a particular patient for such a pro longed period of time depends on many factors, most of which are addressed in the different chapters of this book. The aim of antiviral drug combination therapy for AIDS is ultimately to restore full function of the immune system.

Zustand: New. Offers an extensive assessment of combination therapy of AIDS. In this book, the main focus is put on the Highly Active Antiretroviral Therapy (HAART) but other therapies like salvage therapy are also discussed. It also includes chapters that cover efficacy, treatment, causes of treatment failure, clinical care, guidelines, pharmacology. Editor(s): De Clercq, Erik; Vandamme, Anne-Mieke. Series: Milestones in Drug Therapy. Num Pages: 254 pages, biography. BIC Classification: MJCJ2. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 235 x 163 x 22. Weight in Grams: 532. . 2003. Hardback. . . . . Books ship from the US and Ireland.