9783659937583 - Synthetic Methodologies ~ Biologically Relevant "Privileged Scaffold" von Botta, Lorenzo (3 Ergebnisse)

Paperback. Zustand: Brand New. 128 pages. 8.66x5.87x0.39 inches. In Stock.

Taschenbuch. Zustand: Neu. Synthetic Methodologies ~ Biologically Relevant "Privileged Scaffold" | Lorenzo Botta | Taschenbuch | 128 S. | Englisch | 2019 | LAP LAMBERT Academic Publishing | EAN 9783659937583 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu.

Zustand: Hervorragend. Zustand: Hervorragend | Sprache: Englisch | Produktart: Bücher | Privileged structures are molecular scaffolds with versatile binding properties, such that a single scaffold is able to provide potent and selective ligands for a range of different biological targets through the simple manipulation of the functional groups. In addition, privileged structures typically exhibit good drug-like properties, which in turn leads to more drug-like compound libraries and leads. In this book the possibility to develop a versatile methodology for the syntheis of biologically relevant privileged scaffolds is deeply explored. The first part of the book is focused on the development of a multicomponent approach for the synthesis of Dihydropirans and Sugars. The second part of the book is focused on the synthesis and the biological evaluation, against HIV virus, of derivatives with a rhodaninc structure. Finally, the third part regards the attemps to synthesize the indenic privileged structure as a strategy to obtain the natural product Cyanosporoside.