9783642425448 - glycoscience and microbial adhesion (topics in current chemistry, band 288) (2 Ergebnisse)
Sprache: Englisch
Verlag: Springer, 2014
- Softcover
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Zustand: New. In.
Sprache: Englisch
Verlag: Springer Vieweg, 2014
- Softcover
Anbieter: AHA-BUCH GmbH, Einbeck, DeutschlandAHA-BUCH GmbH
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Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - bacterial carbohydrate recognition are conveyed, covering Gram-positive as well as Gram-negative bacteria, in Chapter 4 Streptococci and Staphylococci, and in Chapter 5, carbohydrate binding specificities of Helicobacter pylori. In Chapter 6, Bitter…sweetness of complexity, the collected reflections on mic- bial adhesion are expanded by a perspective on a broader impact of glycosylation on cellular adhesion, motility and regulatory processes, paralleling the complexity of N-glycan structures on cell surfaces. It highlights particularly how structural details of N-glycans have been causally related to pathological scenarios, with a focus on (1,6)-N-acetylglucosaminyltransferase. In the final chapter, biofilm formation is reviewed, covering knowledge about structure and biosynthesis of polysaccharide intercellular adhesins (PIAs) which are central to biofilm formation. This comprehensive chapter explains all PIA-related principles of medical device-associated infections. It is our hope, that this collection of expert articles, ranging from structural ch- istry and structural biology to biochemistry and medicine, will be a stimulation and motivation for our colleagues in the life sciences. At the same time, we hope that these reflections on microbial adhesion will awake interest in and promote und- standing of the complex processes associated with the glycocalyx and the multif- eted interactions between the host cell and its guest, as well as the biological consequences resulting from this mutual interplay.
