9783642366475 - programmed cells from basic neuroscience to therapy (research and perspectives in neurosciences, 20, band 20) (5 Ergebnisse)
Sprache: Englisch
Verlag: Springer 03 J, 2013
Serie: Buch 10 von 14 - Research and Perspectives in Neurosciences
- Hardcover
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Hardcover. Zustand: Very Good. Programmed Cells from Basic Neuroscience to Therapy: 20 (Research and Perspectives in Neurosciences, 20) This book is in very good condition and will be shipped within 24 hours of ordering. The cover may have some limited signs of wear but the pages are clean, intact and the spine remains undamaged…. This book has clearly been well maintained and looked after thus far. Money back guarantee if you are not satisfied. See all our books here, order more than 1 book and get discounted shipping. .
Sprache: Englisch
Verlag: Springer 01/n /03 J, 2013
Serie: Buch 10 von 14 - Research and Perspectives in Neurosciences
- Hardcover
Anbieter: Bahamut Media, Reading, Vereinigtes KönigreichBahamut Media
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Hardcover. Zustand: Very Good. Shipped within 24 hours from our UK warehouse. Clean, undamaged book with no damage to pages and minimal wear to the cover. Spine still tight, in very good condition. Remember if you are not happy, you are covered by our 100% money back guarantee.
Sprache: Englisch
Verlag: Berlin, Springer Berlin., 2013
Serie: Buch 10 von 14 - Research and Perspectives in Neurosciences
- Hardcover
Anbieter: Universitätsbuchhandlung Herta Hold GmbH, Berlin, DeutschlandUniversitätsbuchhandlung Herta Hold GmbH
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XII, 132 p. Hardcover. Versand aus Deutschland / We dispatch from Germany via Air Mail. Einband bestoßen, daher Mängelexemplar gestempelt, sonst sehr guter Zustand. Imperfect copy due to slightly bumped cover, apart from this in very good condition. Stamped. Stamped. Research and Perspectives in Neurosciences ; 20. Sprache: Engl…isch.
Sprache: Englisch
Verlag: Springer-Verlag GmbH, 2013
Serie: Buch 10 von 14 - Research and Perspectives in Neurosciences
- Hardcover
Anbieter: Buchpark, Trebbin, DeutschlandBuchpark
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Zustand: Hervorragend. Zustand: Hervorragend | Sprache: Englisch | Produktart: Bücher | Keine Beschreibung verfügbar.
Sprache: Englisch
Verlag: Springer, Berlin, Springer Berlin Heidelberg, Springer, 2013
Serie: Buch 10 von 14 - Research and Perspectives in Neurosciences
- Hardcover
Anbieter: AHA-BUCH GmbH, Einbeck, DeutschlandAHA-BUCH GmbH
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EUR 162,91
EUR 61,75 VersandVersand von Deutschland nach USAAnzahl: 2 verfügbar
Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The recent advances in Programming Somatic Cell (PSC) including induced Pluripotent Stem Cells (iPS) and Induced Neuronal phenotypes (iN), has changed our experimental landscape and opened new possibilities. The advances in PSC have provided an important to…ol for the study of human neuronal function as well as neurodegenerative and neurodevelopmental diseases in live human neurons in a controlled environment. For example, reprogramming cells from patients with neurological diseases allows the study of molecular pathways particular to specific subtypes of neurons such as dopaminergic neurons in Parkinson's Disease, Motor neurons for Amyolateral Sclerosis or myelin for Multiple Sclerosis. Detecting disease-specific molecular signatures in live human brain cells, opens possibilities for early intervention therapies and new diagnostic tools. Importantly, once the neurological neural phenotype is detected in vitro, the so-called 'disease-in-a-dish' approach allows for the screening of drugs that can ameliorate the disease-specific phenotype. New therapeutic drugs could either act on generalized pathways in all patients or be patient-specific and used in a personalized medicine approach. However, there are a number of pressing issues that need to be addressed and resolved before PSC technology can be extensively used for clinically relevant modeling of neurological diseases. Among these issues are the variability in PSC generation methods, variability between individuals, epigenetic/genetic instability and the ability to obtain disease-relevant subtypes of neurons . Current protocols for differentiating PSC into specific subtypes of neurons are under development, but more and better protocols are needed. Understanding the molecular pathways involved in human neural differentiation will facilitate the development of methods and tools to enrich and monitor the generation of specific subtypes of neurons that would be more relevant in modeling differentneurological diseases.
