9783540749653 - Retrotransposition, Diversity and the Brain (Research and Perspectives in Neurosciences) (8 Ergebnisse)

Hardcover. Zustand: Bon. Ancien livre de bibliothèque. Légères traces d'usure sur la couverture. Couverture différente. Edition 2007. Ammareal reverse jusqu'à 15% du prix net de cet article à des organisations caritatives. ENGLISH DESCRIPTION Book Condition: Used, Good. Former library book. Slight signs of wear on the cover. Different cover. Edition 2007. Ammareal gives back up to 15% of this item's net price to charity organizations.

Zustand: New. pp. xii + 123.

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Zustand: Used. pp. xii + 123.

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Zustand: Sehr gut. Zustand: Sehr gut | Sprache: Englisch | Produktart: Bücher | The human brain is remarkably complex, permitting sophisticated behavioural rep- toires, such as languages, tool use, self-awareness, symbolic thought, cultural learning and consciousness. Each human being is different, due in part to the uniqueness of the neuronal heterogeneity and interconnections in our brains. Brain complexity and neuronal diversity are strongly related. The diversity of single neurons provides the underpinnings for how neuronal circuits operate. How and when neuronal diversity is generated, both in embryonic and adult neurogenesis, remain unknown. In the immune system, the highly diverse array of antigen receptors can be - tributed to the stochastic nature of the recombination process in somatic precursor cells, causing permanent changes in DNA and gene expression. This diverse population is then the target of selective processes that favor the correct antigen-receptor match and eliminate those with inadequate speci?cities, accounting for the rapid kinetics and immense diversity observed in vivo. Evidence for a possible similarity between the nervous and immune systems came from studies with mice de?cient in DNA double strand break (DSB) repair. Lessons learned from the discovery of the mechanism for diversityinthe immune system maybe usefultothe investigation ofthe mechanism of diversity in neurons.

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Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The human brain is remarkably complex, permitting sophisticated behavioural rep- toires, such as languages, tool use, self-awareness, symbolic thought, cultural learning and consciousness. Each human being is different, due in part to the uniqueness of the neuronal heterogeneity and interconnections in our brains. Brain complexity and neuronal diversity are strongly related. The diversity of single neurons provides the underpinnings for how neuronal circuits operate. How and when neuronal diversity is generated, both in embryonic and adult neurogenesis, remain unknown. In the immune system, the highly diverse array of antigen receptors can be - tributed to the stochastic nature of the recombination process in somatic precursor cells, causing permanent changes in DNA and gene expression. This diverse population is then the target of selective processes that favor the correct antigen-receptor match and eliminate those with inadequate speci cities, accounting for the rapid kinetics and immense diversity observed in vivo. Evidence for a possible similarity between the nervous and immune systems came from studies with mice de cient in DNA double strand break (DSB) repair. Lessons learned from the discovery of the mechanism for diversityinthe immune system maybe usefultothe investigation ofthe mechanism of diversity in neurons.