Anbieter: Universitätsbuchhandlung Herta Hold GmbH, Berlin, Deutschland
35 Figs., 8 Tabs., VII, 391 p. Hardcover. Versand aus Deutschland / We dispatch from Germany via Air Mail. Einband bestoßen, daher Mängelexemplar gestempelt, sonst sehr guter Zustand. Imperfect copy due to slightly bumped cover, apart from this in very good condition. Stamped. Current Topics in Microbiology and Immunology, Vol. 316. Sprache: Englisch.
Anbieter: Romtrade Corp., STERLING HEIGHTS, MI, USA
Zustand: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.
Anbieter: Majestic Books, Hounslow, Vereinigtes Königreich
EUR 182,69
Anzahl: 1 verfügbar
In den WarenkorbZustand: Used. pp. viii + 392.
Anbieter: Biblios, Frankfurt am main, HESSE, Deutschland
Zustand: Used. pp. viii + 392.
Sprache: Englisch
Verlag: Springer Berlin Heidelberg, 2007
ISBN 10: 354071328X ISBN 13: 9783540713289
Anbieter: moluna, Greven, Deutschland
EUR 180,07
Anzahl: Mehr als 20 verfügbar
In den WarenkorbGebunden. Zustand: New.
Sprache: Englisch
Verlag: Springer Berlin Heidelberg, Springer Berlin Heidelberg, 2007
ISBN 10: 354071328X ISBN 13: 9783540713289
Anbieter: AHA-BUCH GmbH, Einbeck, Deutschland
Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Over the last half of century interferon (IFN), originally discovered as an antiviral protein, has developed from an inhibitor of viral replication to a major force in the antiviral response. Initially studied only by few virologists, IFN was generally considered as a poorly defined protein of limited importance. The development of molecular techniques lead to the identification of a family of IFN genes and has shown an unexpected complexity of type I IFN genes and their expression. Presently, some aspects of the of the pathogen mediated induction of IFN gene expression are understood at molecular level, while others are still at the stage of description. Both Toll like receptors and cytoplasmic RNA helicases were shown to recognize viral nucleic acids and the basis of a distinct recognition of viral nucleic acids from the cellular ones are emerging. Important insights on the virus recognition entity, leading to the expression of interferon and interferon induced genes, have been made in the recent year, which are challenging the accepted concept of the critical role of dsRNA in IFN induction. The availability of genetically modified mice that are lacking either essential components of the interferon inducing pathway, or interferon signaling pathway fully confirmed the original idea, made soon after its discovery, that interferon is the first cellular defense against viral infection.